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Journal Articles

Crowdsourced High-Risk Classifiers for Multiple Myeloma Patients Commonly Identify PHF19 As a Robust Progression Biomarker

Michael J Mason, PhD, Carolina D. Schinke, MD, Christine Eng, PhD, Fadi Towfic, PhD, Fred Gruber, PhD, Brian S. White, Yi Cui, PhD, Bailiang Li, PhD, Thomas Yu, BS, William S. Dalton, PhDMD, Hartmut Goldschmidt, MD, Herve Avet-Loiseau, MD PhD, Mehmet Samur, PhD, Maria Ortiz, Matthew Trotter, PhD, Boris Hayete, PhD, Andrew Dervan, Erin Flynt, Hongyue Dai, PhD, Douglas Bassett, PhD, Pieter Sonneveld, Kenneth H. Shain, MD PhD, Nikhil C. Munshi, MD, Daniel Auclair, Dirk Hose, MD, Gareth Morgan, MDPhDFRCP, Jonathan Göke, PhD, Brian A Walker, PhD, Anjan Thakurta, Justin Guinney, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4370.
https://doi.org/10.1182/blood-2019-127362
Published: 2019
Journal Articles

Preclinical Validation Studies Support Causal Machine Learning Based Identification of Novel Drug Targets for High-Risk Multiple Myeloma

Arnold Bolomsky, Fred Gruber, PhD, Kathrin Stangelberger, MSc, Leon Furchtgott, PhD, Dominik Arnold, Puja Raut, Diane Wuest, PhD, Karl Runge, Iya Khalil, Niklas Zojer, MD, Nikhil Munshi, MD, Boris Hayete, PhD, Heinz Ludwig, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3210.
https://doi.org/10.1182/blood-2018-99-117886
Published: 2018
Journal Articles

Multiple Myeloma Drivers of High Risk and Response to Stem Cell Transplantation Identified By Causal Machine Learning: Out-of-Cohort and Experimental Validation

Leon Furchtgott, PhD, Arnold Bolomsky, PhD, Fred Gruber, PhD, Mehmet Kemal Samur, PhD, Jonathan J. Keats, PhD, Jennifer Yesil, MS, Kathrin Stangelberger, MSc, Michel Attal, MD PhD, Philippe Moreau, MDPhD, Hervé Avet-Loiseau, MD PhD, Karl Runge, PhD, Diane Wuest, PhD, Kelly Rich, Iya Khalil, PhD, Boris Hayete, PhD, Heinz Ludwig, MD, Nikhil Munshi, MD, Daniel Auclair, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3029.
https://doi.org/10.1182/blood.V130.Suppl_1.3029.3029
Published: 2017
Journal Articles

Bayesian Network Models of Multiple Myeloma: Drivers of High Risk and Durable Response

Fred Gruber, PhD, Jonathan J Keats, PhD, Kyle McBride, MS, Karl Runge, PhD, Diane Wuest, Tiffany Hadzi, Mary Derome, MS, Sagar Lonial, MD FACP, Iya Khalil, PhD, Boris Hayete, Daniel Auclair, PhD
Journal: Blood
Blood (2016) 128 (22): 4406.
https://doi.org/10.1182/blood.V128.22.4406.4406
Published: 2016
Journal Articles

Investigation of Mechanisms of Response in Multiple Myeloma Via Bayesian Causal Inference: An Early Analysis of the Commpass Study Data

Fred Gruber, PhD, Boris Hayete, PhD, Jonathan J Keats, PhD, Kyle McBride, MS, Runge Karl, PhD, Mary Derome, MS, Sagar Lonial, MD, Iya Khalil, PhD, Daniel Auclair, PhD
Journal: Blood
Blood (2015) 126 (23): 1794.
https://doi.org/10.1182/blood.V126.23.1794.1794
Published: 2015