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Journal Articles

Pharmacokinetics, Biodistribution and Anti-CD19 CAR Expression Kinetics in Vitro and after In Vivo Delivery of a CD8-Targeted Fusosome in NSG Mice

Shalu Sharma Sharma, Vishal Khatri, Vasily Vagin, Prasanna Baskar, Paige Chung, Salvatore Iovino, Joohwan Kim, Chiderah Abani, Samantha Crocker, Anna Liang, Shannon Joyce, Jenny Migliaccio, Gauri Oza, Kerrie Enger, Alicia Sabbio, Hemant Chavan, Justine Cunningham, Trevor McGill, Boris Gorovits, Bindu Varghese, Donna Dambach
Journal: Blood
Blood (2022) 140 (Supplement 1): 12976–12977.
https://doi.org/10.1182/blood-2022-169422
Published: 2022
Journal Articles

In Vivo Delivery of a CD20 CAR Using a CD8-Targeted Fusosome in Southern Pig-Tail Macaques ( M. nemestrina ) Results in B Cell Depletion

Justine Cunningham, Sundeep Chandra, Akinola Emmanuel, Allyse Mazzarelli, Carmela Passaro, Paige Baldwin, Michelle Nguyen-McCarty, Carrie Rocca, Shannon Joyce, Joohwan Kim, Vasily Vagin, James Kaczmarek, Hemant Chavan, Heather Jewell, Yonatan Lipsitz, Misha Shamashkin, Kelan Hlavaty, Jason Rodriguez, Carl Co, Pattie Cruite, Hanane Ennajdaoui, Victoria Duback, Jess Elman, Shirisha Amatya, Caspian Harding, Sergey Lyubinetsky, Vidur Patel, Lauren Pepper, Albert Ruzo, Salvatore Iovino, Bindu Varghese, Aaron E. Foster, Boris Gorovits, Kutlu Elpek, Michael Laska, Trevor McGill, Jagesh V Shah, Terry J. Fry, Donna Dambach
Journal: Blood
Blood (2021) 138 (Supplement 1): 2769.
https://doi.org/10.1182/blood-2021-148709
Published: 2021
Journal Articles

CD20xCD3 Bispecific Fully Human Antibody Induces Potent Anti-Tumor Activity Against CD20-Expressing Tumors in Immune Competent Mice Humanized for CD20 and CD3

Bindu Varghese, PhD, Jayanthi Menon, Luis Rodriguez, Kara Olson, Pamela Krueger, Tammy Huang, PhD, Eric Smith, PhD, Gavin Thurston, PhD, Jessica R. Kirshner, PhD
Journal: Blood
Blood (2015) 126 (23): 818.
https://doi.org/10.1182/blood.V126.23.818.818
Published: 2015
Journal Articles

A Novel CD20xCD3 Bispecific Fully Human Antibody Induces Potent Anti-Tumor Effects Against B Cell Lymphoma in Mice

Bindu Varghese, PhD, Jayanthi Menon, Luis Rodriguez, Lauric Haber, Kara Olson, Paurene Duramad, PhD, Adelekan Oyejide, Eric Smith, PhD, Gavin Thurston, PhD, Jessica Kirshner, PhD
Journal: Blood
Blood (2014) 124 (21): 4501.
https://doi.org/10.1182/blood.V124.21.4501.4501
Published: 2014
Journal Articles

A CpG-loaded tumor cell vaccine induces antitumor CD4 + T cells that are effective in adoptive therapy for large and established tumors

Matthew J. Goldstein, Bindu Varghese, Joshua D. Brody, Ranjani Rajapaksa, Holbrook Kohrt, Debra K. Czerwinski, Shoshana Levy, Ronald Levy
Journal: Blood
Blood (2011) 117 (1): 118–127.
https://doi.org/10.1182/blood-2010-06-288456
Published: 2011
Includes: Supplemental data
Journal Articles

CD137 Identifies a Population of Regulatory T Cells That Inhibit Anti-Tumor Immune Responses In Adoptive Immunotherapy

Matthew J Goldstein, BA, Holbrook E Kohrt, MD, Roch Houot, MD/PhD, Bindu Varghese, PhD, Jack T Lin, PhD, Erica Swanson, BA, Ronald Levy, MD
Journal: Blood
Blood (2010) 116 (21): 2093.
https://doi.org/10.1182/blood.V116.21.2093.2093
Published: 2010
Journal Articles

Adoptive Cell Therapy for Lymphoma: Use of CpG-Loaded Tumor Cells to Generate Potent Anti-Tumor CD4 T Cell Immunity.

Matthew J Goldstein, Bindu Varghese, PhD, Ranjani Rajapaksa, PhD, Joshua Brody, MD, Shoshana Levy, PhD, Ronald Levy, MD
Journal: Blood
Blood (2009) 114 (22): 929.
https://doi.org/10.1182/blood.V114.22.929.929
Published: 2009
Journal Articles

Therapeutic Antibody Targeting of CD47 Synergizes with Rituximab to Completely Eradicate Human B-Cell Lymphoma Xenografts.

Mark P. Chao, BA, Ash A Alizadeh, MD, PhD, Chad Z. Tang, MS, June Helen Myklebust, PhD, Bindu Varghese, PhD, Max Jan, BA, Ronald Levy, MD, Irving L. Weissman, MD, Ravindra Majeti, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2716.
https://doi.org/10.1182/blood.V114.22.2716.2716
Published: 2009
Journal Articles

Generation of CD8 + T cell–mediated immunity against idiotype-negative lymphoma escapees

Bindu Varghese, Adam Widman, James Do, Behnaz Taidi, Debra K. Czerwinski, John Timmerman, Shoshana Levy, Ronald Levy
Journal: Blood
Blood (2009) 114 (20): 4477–4485.
https://doi.org/10.1182/blood-2009-05-223263
Published: 2009
Journal Articles

Folate Receptor Saturation, Recycling, and Release Kinetics in Activated Macrophages

Bindu Varghese, PhD, Erina Vlashi, PhD, Philip S. Low, PhD
Journal: Blood
Blood (2008) 112 (11): 4655.
https://doi.org/10.1182/blood.V112.11.4655.4655
Published: 2008
Journal Articles

Generation of CD8 T Cell-Mediated Protective Immunity against Tumor Escapees

Bindu Varghese, PhD, Behnaz Taidi, Adam Widman, James Do, R. Levy
Journal: Blood
Blood (2008) 112 (11): 2623.
https://doi.org/10.1182/blood.V112.11.2623.2623
Published: 2008