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Journal Articles

Planned Interim Safety Analysis of the Phase 3 Randomized Trial of Selinexor and Lenalidomide Versus Lenalidomide Maintenance Post Autologous Stem Cell Transplant for Patients with Newly Diagnosed Multiple Myeloma (ALLG MM23; Sealand)

Hang Quach, Masa Lasica, Michael Low, Peter Mollee, Hock Choong Lai, Nicole Wong Doo, Jay Hocking, Philip Campbell, Nicholas E. Murphy, M Hasib Sidiqi, David Routledge, Jessica Heenan, Noemi Horvath, Richard Eek, William E. P. Renwick, Douglas Stuart Lenton, Lauren J Child, Georgia McCaughan, Belinda E Butcher, Deepmala Mazumdar, Anna Kalff
Journal: Blood
Blood (2023) 142 (Supplement 1): 2023.
https://doi.org/10.1182/blood-2023-185169
Published: 2023
Journal Articles

Secondary Analysis of the MM21 Trial: Response Adaptive Salvage Treatment with Daratumumab-Lenalidomide-Dexamethasone (DRd) for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients Failing Front-Line Bortezomib-Based Induction Therapy

Sueh-li Lim, John Reynolds, Hang Quach, Anna Hutchinson, Ian H Kerridge, Jane Estell, Craig wallington-Gates, Anna Kalff, Flora Yuen, Andrew Spencer
Journal: Blood
Blood (2022) 140 (Supplement 1): 10174–10176.
https://doi.org/10.1182/blood-2022-170697
Published: 2022
Journal Articles

Preliminary Analysis of the MM21 Trial: Response Adaptive Salvage Treatment with Daratumumab-Lenalidomide-Dexamethasone (DRd) for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients Failing Front-Line Bortezomib-Based Induction Therapy

Sueh-li Lim, John Reynolds, Hang Quach, Anna Hutchinson, Ian H Kerridge, Jane Estell, Wojt Janowski, Craig Thomas Wallington-Beddoe, Anna Kalff, Flora Yuen, Andrew Spencer
Journal: Blood
Blood (2021) 138 (Supplement 1): 1665.
https://doi.org/10.1182/blood-2021-152102
Published: 2021
Journal Articles

Response Adaptive Salvage Treatment with Carfilzomib-Thalidomide-Dexamethasone for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients Failing Front-Line Bortezomib-Based Induction Therapy - Final Analysis from the Australasian Leukemia and Lymphoma Group (ALLG) MM17 Trial

Rose Turner, Hang Quach, Noemi Horvath, Ian H Kerridge, Flora Yuen, Edwin Sze-Hung Lee, Edward S. Morris, Anna Kalff, Krystal Bergin, Shreerang Sridesai, Malgorzata Gorniak, Sridurga Mithraprabhu, Tiffany Khong, John Reynolds, Andrew Spencer
Journal: Blood
Blood (2021) 138 (Supplement 1): 1663.
https://doi.org/10.1182/blood-2021-152034
Published: 2021
Journal Articles

Immune Cell Profiles in Patients Treated with Lenalidomide and Alternate Day Prednisolone Maintenance Post Upfront ASCT for Multiple Myeloma (LEOPARD Trial)

Anna Kalff, MBBS (Hons) FRACP FRCPA, Sam Norton, PhD, Tiffany Khong, BSc, PhD, Malarmathy Ramachandran, Mary H. Young, PhD, William Pierceall, Anjan Thakurta, Udo Oppermann, PhD, Manman Guo, John Reynolds, PhD, Andrew Spencer
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-141746
Published: 2020
Journal Articles

Phase 1, First-in-Human Study of MEDI2228, a BCMA-Targeted ADC in Patients with Relapsed/Refractory Multiple Myeloma

Shaji K. Kumar, MD, Magdalini Migkou, Manisha Bhutani, MD, Andrew Spencer, Sikander Ailawadhi, Anna Kalff, MBBS (Hons) FRACP FRCPA, Farzana Walcott, Nabendu Pore, Diana Gibson, Fujun Wang, Lily Cheng, Ioannis Kagiampakis, Marna Williams, Krista Kinneer, Yu Jiang, Jeffrey Zonder, Jeremy Larsen, Shreerang Sirdesai, Andrew J. Yee, Meletios A Dimopoulos
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-136375
Published: 2020
Journal Articles

Trends in Outcomes in Australia and New Zealand in Autologous Stem Cell Transplantation in Older Patients with Multiple Myeloma: An Australasian Bone Marrow Transplant Recipient Registry Study

Georgia J McCaughan, MBBS, Steven Tran, BEng MBiomedE, Simon Durrant, MBBS FRCP FRCPath, Simon J Harrison, MBBS MRCP (UK) PhDFRCPath (UK) FRACP, James Morton, MBBS BSci (MD FRACP FRCPA GAICD, Noemi Horvath, MB ChB FRACP FRCPA, Andrew Spencer, Ian H. Kerridge, FRACP FRCPA MPhil BA, Jeremy An Ke Er, MBBS, Luani Barge, MChD, BSc, Adam Bryant, MBBS (Hon) PhDFRACP FRCPA, Robin J Filshie, MBChB, PhD FRACP, FRCPA, Emily Choong, BSc MBBS, Hock Choong Lai, MBBS, FRACP, FRCPA, Campbell Tiley, MBBS FRACP, Anthony K Mills, MBBS FRACP FRCPA, Andrew Butler, MB ChB(Edin), MRCP, MRCPath, John Moore, MB.BS, MD FRACP, FRCPA, Mark Hertzberg, MBBS PhDFRACP FRCPA, Glen A Kennedy, MBBS FRACP FRCPA, P. Joy Ho, MB.BS. (Hons), D.Phil (Oxon), FRACP, FRCPA, FFSc(RCPA), M Hasib Sidiqi, MBBS, John Bashford, BSc MBBS FRACP FRCPA, David Routledge, BSc (Hons) MBChB MSc PGCert MRCP FRCPath UK RACP, Kerry Taylor, MBBS(Hons) FRACP FRCPA, Cindy H. Lee, MBBS FRACP FRCPA, Anna Kalff, MBBS (Hons) FRACP FRCPA, Wei Xia, MBBS PhD, Nada Hamad, MBBS,BSc,MSc,FRACP FRCPA
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-138991
Published: 2020
Journal Articles

A Longitudinal Evaluation of Euroflow and Combined Quantitative Immunoprecipitation (QIP) and Free Light Chain (FLC) Mass Spectometry (MS) in Functional High Risk Multiple Myeloma

Andrew Spencer, DM, Tiffany Khong, BSc, PhD, Flora Yuen, BBiomedSc, Hannah Victoria Giles, FRCPath, MRCP, Malgorzata Gorniak, BSc, Hang Quach, MBBS, FRACP, FRCPA, MD, Noemi Horvath, MBBS FRACP FRCPA, Ian H. Kerridge, FRACP,FRCPA,MPhil,BA, Edwin Sze-Hung Lee, MD FRACP, FRCP, FRCPA, FRCPath, Krystal Bergin, Shreerang Sridesai, MBBS, FRACP, FRCPA, Anna Kalff, MBBS, John Reynolds, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3090.
https://doi.org/10.1182/blood-2019-129760
Published: 2019
Journal Articles

Identification of Novel Immune Cell Populations in Lenalidomide Refractory Relapsed Multiple Myeloma Patients Treated with Pomalidomide and Low Dose Dexamethasone

Anna Kalff, MBBS, Tiffany Khong, BSc, PhD, Malarmathy Ramachandran, Sam Norton, PhD, Andrew Mitchell, PhD, John Reynolds, PhD, Hang Quach, MBBS, FRACP, FRCPA, MD, P Joy Ho, MBBS(Syd) DPhil(Oxon) FRACP FRCPA FFSc(RCPA), Noemi Horvath, MBBS FRACP FRCPA, Peter Mollee, MBBS, MMSc, FRACP, FRCPA, Nola Kennedy, Roslyn Kemp, Andrew Spencer, DM
Journal: Blood
Blood (2019) 134 (Supplement_1): 3186.
https://doi.org/10.1182/blood-2019-130154
Published: 2019
Journal Articles

A Sequential Cohort Study Comparing Kappamab Alone to Kappamab, Lenalidomide and Low Dose Dexamethasone in Kappa-Restricted Relapsed Refractory Multiple Myeloma (AMaRC 01-16)

Anna Kalff, MBBS, Jake Shortt, MBBS FRACP FRCPA PhD, Flora Yuen, BBiomedSc, John Reynolds, PhD, Hang Quach, MBBS, FRACP, FRCPA, MD, Craig Thomas Wallington-Beddoe, BSc,MBBS,PhDFRACP,FRCPA, Patricia Walker, MBBS, BMedSci, FRACP, FRCPA, Simon Harrison, MBBS, MRCP, FRCPath, FRACP, PhD, Rosanne Dunn, PhD, Andrew Spencer, DM
Journal: Blood
Blood (2019) 134 (Supplement_1): 3144.
https://doi.org/10.1182/blood-2019-130084
Published: 2019
Journal Articles

Phase 2 Trial of the Combination of Ixazomib, Thalidomide and Dexamethasone (ITD) in Relapsed/Refractory Myeloma: Planned Preliminary Analysis

Krystal Bergin, Flora Yuen, BBiomedSc, Craig Thomas Wallington-Beddoe, BSc, MBBS, PhD FRACP, FRCPA, Anna Kalff, MBBS, Shreerang Sirdesai, MBBS, FRACP, FRCPA, John Reynolds, PhD, Andrew Spencer, MBBS, MD FRACP, FRCPA
Journal: Blood
Blood (2018) 132 (Supplement 1): 3265.
https://doi.org/10.1182/blood-2018-99-118172
Published: 2018
Journal Articles

Pomalidomide Alone or in Combination with Low Dose Dexamethasone As Maintenance Following Induction with Pomalidomide and Low Dose Dexamethasone in Relapsed and Refractory Myeloma (ALLG MM14)

Anna Kalff, MBBS, Nola Kennedy, John Reynolds, PhD, Hang Quach, MDFRACP,FRCPA,MBBS, Phoebe Joy Ho, MBBS, Noemi Horvath, MBBS FRACP FRCPA, Peter Mollee, FRACP, FRCPA, MBBS, MMSc, James M. D'Rozario, MBBS, FRACP, FRCPA, Kerry Taylor, FRACP,FRCPA,MBBS, Jane Estell, FRACP, Andrew Spencer, MBBS, MD FRACP, FRCPA
Journal: Blood
Blood (2018) 132 (Supplement 1): 1986.
https://doi.org/10.1182/blood-2018-99-118231
Published: 2018
Journal Articles

Preliminary Analysis of the Australasian Leukaemia and Lymphoma Group (ALLG) MM17 Trial: Response Adaptive Salvage Treatment with Carfilzomib-Thalidomide-Dexamethasone (KTd) for Newly Diagnosed Transplant Eligible Multiple Myeloma Patients Failing Front-Line Bortezomib-Based Induction Therapy

Andrew Spencer, MBBS, FRACP, FRCPA, DM, Hang Quach, MD FRACP, FRCPA, MBBS, Noemi Horvath, MBBS FRACP FRCPA, Ian H. Kerridge, FRACP, FRCPA, MPhil, BA, Flora Yuen, BBiomedSc, Edwin Sze-Hung Lee, MD FRACP, FRCP, FRCPA, FRCPath, Edward S. Morris, BMBS, DM, Anna Kalff, MBBS, Krystal Bergin, Shreerang Sirdesai, MBBS, FRACP, FRCPA, Malgorzata Gorniak, BSc, Sridurga Mithraprabhu, PhD MSc, Tiffany Khong, BSc, PhD, John Reynolds, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3279.
https://doi.org/10.1182/blood-2018-99-113982
Published: 2018
Journal Articles

Identification of Acetylation, Immune Cell Alterations and Gene Signature As Dynamic Biomarkers of Response to Panobinostat Treatment in Multiple Myeloma Patients

Sridurga Mithraprabhu, PhD MSc, Ioanna Savvidou, MD, Malarmathy Ramachandran, Anna Kalff, MBBS, Tiffany T. Khong, BSc,PhD, Kate Reed, John Reynolds, PhD, Andrew Spencer, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1823.
https://doi.org/10.1182/blood.V130.Suppl_1.1823.1823
Published: 2017
Journal Articles

High Risk Multiple Myeloma: Better Outcomes with Upfront Tandem Autologous- Non-Myelo Ablative Allogeneic Stem Cell Transplantation Compared to Upfront Autologous Stem Cell Transplantation

Anish Puliyayil Nair, MD DM, FRACP, Cindy Lee, FRACP, FRCPA, Anna Kalff, MBBS, FRACP, FRCPA, Patricia A. Walker, MBBS, FRACP, FRCPA, Krystal Bergin, Jay Hocking, MD PhDstudent, Sue Morgan, FRACP, FRCPA, MBBS, Daniela Klarica, RN, Jenny Muirhead, Andrew Spencer, Oi Lin Lee, Noemi Horvath, MB, ChB, FRACP, FRCPA
Journal: Blood
Blood (2016) 128 (22): 4684.
https://doi.org/10.1182/blood.V128.22.4684.4684
Published: 2016
Journal Articles

A 2-Stage Phase II Study of Panobinostat Consolidation in Multiple Myeloma (MM) Patients with < CR Following Single High-Dose Chemotherapy (HDT) Conditioned Autologous Stem Cell Transplantation (ASCT) As Part of First Line Therapy

Anna Kalff, MBBS, FRACP, FRCPA, Sridurga Mithraprabhu, PhD, Tiffany T. Khong, PhD, Malarmathy Ramachandran, Kate Reed, Hang Quach, MBBS (Hons), FRACP, FRCPA, MD, Patricia A. Walker, MBBS, FRACP, FRCPA, Krystal Bergin, Andrew Spencer
Journal: Blood
Blood (2016) 128 (22): 4515.
https://doi.org/10.1182/blood.V128.22.4515.4515
Published: 2016
Journal Articles

Roar: A Phase Ib Trial of Oral Azacitidine (CC-486) in Combination with Lenalidomide and Dexamethasone (Rd) for Patients with Relapsed and/or Refractory (R/R) Multiple Myeloma Who Have Failed a Prior Lenalidomide-Containing Regimen

Anna Kalff, MBBS, FRACP, FRCPA, Kate Reed, Tiffany T. Khong, PhD, Sridurga Mithraprabhu, PhD, Malarmathy Ramachandran, John Reynolds, Krystal Bergin, Anjan Thakurta, PhD, Maria Wang, PhD, Andrew Spencer, Roberto Guzman, Suzana Cuoto, Yan Ren, MD
Journal: Blood
Blood (2016) 128 (22): 2121.
https://doi.org/10.1182/blood.V128.22.2121.2121
Published: 2016
Journal Articles

Mutational Characterisation and Tracking Disease Progression Using Circulating Cell-Free Tumor DNA in Multiple Myeloma Patients

Sridurga Mithraprabhu, PhD, Tiffany Khong, BSc, PhD, Malarmathy Ramachandran, Annie W.S. Chow, Daniela Klarica, RN, Laura Mai, Stephanie Walsh, David Broemeling, Andre Marziali, Matthew Wiggin, Jay Hocking, MD PhDstudent, Anna Kalff, MBBS, FRACP, FRCPA, Brian G.M. Durie, MD, Andrew Spencer
Journal: Blood
Blood (2016) 128 (22): 3280.
https://doi.org/10.1182/blood.V128.22.3280.3280
Published: 2016
Journal Articles

Evaluation of Circulating Tumour DNA for the Mutational Characterisation of Multiple Myeloma

Andrew Spencer, Sridurga Mithraprabhu, Post doc, Malarmathy Ramachandran, Daniela Klarica, RN, Jay Hocking, MD, Laura Mai, Stephanie Walsh, David Broemeling, Andre Marziali, Anna Kalff, MD, Matthew Wiggin, Brian G. M. Durie, MD, Tiffany T. Khong, PhD
Journal: Blood
Blood (2015) 126 (23): 368.
https://doi.org/10.1182/blood.V126.23.368.368
Published: 2015
Journal Articles

Autologous Stem Cell Transplantation (ASCT) Followed By Outpatient-Based Non-Myeloblative Allogeneic (NMA) Stem Cell Transplantation (Tandem Auto-Allo) for Biologically Adverse Multiple Myeloma (MM). a Single Centre Experience from Australia

Anish Puliyayil Nair, MD DM, Patricia A. Walker, MBBS, FRACP, FRCPA, Anna Kalff, MBBS, FRACP, FRCPA, Krystal Bergin, MBBS, Sharon Avery, MBBS (Hons), FRACP, FRCPA, David J. Curtis, MD, PhD, Sushrut S. Patil, FRACP, FRCPA, Jenny Muirhead, Tongted Phomoonna, Daniela Klarica, RN, Andrew Spencer
Journal: Blood
Blood (2015) 126 (23): 2030.
https://doi.org/10.1182/blood.V126.23.2030.2030
Published: 2015