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Andrea Santoni
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Journal Articles

Targeting DNA2 Overcomes Myeloma Cells' Metabolic Reprogramming in Response to DNA Damage

Natthakan Thongon, Andrea Santoni, Jintan Liu, Natalia Baran, Feiyang Ma, Christopher Jackson, Pamela Lockyer, Irene Ganan-Gomez, Vera Adema, Ashley Rose, Matteo Marchesini, Yun Qing, Min Jin Ha, Caleb Class, Matteo Pellegrini, Lin Tan, Philip Lorenzi, Marina Konopleva, Simona Colla
Journal: Blood
Blood (2021) 138 (Supplement 1): 1573.
https://doi.org/10.1182/blood-2021-148992
Published: 2021
Journal Articles

SF3B1 -Mutant Myelodysplastic Syndrome with Ringed Sideroblasts (MDS-RS) at the Single-Cell Level

Rashmi Kanagal-Shamanna, MD, Vera Adema, PhD, Feiyang Ma, Bs, Andrea Santoni, PhD, Hui Yang, MD PhD, Irene Ganan-Gomez, PhD, Natthakan Thongon, PhD, Guillermo Montalban-Bravo, MD, Matteo Pellegrini, PhD, Carlos E. Bueso-Ramos, MD PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50–51.
https://doi.org/10.1182/blood-2020-141928
Published: 2020
Journal Articles

ILF2 Antisense Oligonucleotide Therapy and a CRISPR/Cas9-Based Screening for DNA Repair Effectors Identify Synthetic Lethal Approaches Enhancing Myeloma Cells Sensitivity to DNA Damage

Natthakan Thongon, PhD, Christopher Jackson, BS, Pamela Lockyer, MS, Jintan Liu, Andrea Santoni, PhD, Ashley Rose, BS, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 685.
https://doi.org/10.1182/blood-2019-129286
Published: 2019
Journal Articles

Telomere Damage Maintains Hematopoietic Stem Cells (HSCs) in an Activated Metabolic State, Which Compromises Their Self-Renewal Capability

Andrea Santoni, PhD, Elena Fiorini, MS, Fides D Lay, PhD BSc, Matteo Marchesini, PhD, Yamini Ogoti, Christopher Jackson, Ashley Rose, Karen Clise-Dwyer, PhD, Irene Ganan-Gomez, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 174.
https://doi.org/10.1182/blood-2018-174
Published: 2018
Journal Articles

Cell-Type Specific Mechanisms of Hematopoietic Stem Cell (HSC) Expansion Underpin Progressive Disease in Myelodysplastic Syndromes (MDS) and Provide a Rationale for Targeted Therapies

Irene Ganan-Gomez, PhD, Ana Alfonso, MD PhD, Hui Yang, PhDMD, Andrea Santoni, PhD, Valentina Marchica, MS, Elena Fiorini, MS, Guillermo Montalban-Bravo, MD, Yamini Ogoti, Ganiraju Manyam, Shan Jiang, Naran Bao, Christopher Jackson, Ashley Rose, Rashmi Kanagal-Shamanna, MD, Carlos E. Bueso-Ramos, MD PhD, Benedetta Cambò, MD, Nicola Giuliani, MD PhD, Monica Crugnola, MD, Marina Y. Konopleva, MD PhD, Karen Clise-Dwyer, PhD, Guillermo Garcia-Manero, MD, Simona Colla, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1798.
https://doi.org/10.1182/blood-2018-99-116881
Published: 2018