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Andrea Annoni
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Journal Articles

Poisoning of Healthy Hematopoiesis Is an Unanticipated Mechanism Driving Clonal Dominance in Vexas Syndrome

Martina Fiumara, Raffaella Molteni, Corrado Campochiaro, Roberta Alfieri, Guido Pacini, Alessandro Tomelleri, Elisa Diral, Angelica Varesi, Alessandra Weber, Pamela Quaranta, Luisa Albano, Chiara Gaddoni, Luca Basso-Ricci, Davide Stefanoni, Gregorio Maria Bergonzi, Andrea Annoni, Maddalena Panigada, Eleonora Cantoni, Daniele Canarutto, Stephanie Z Xie, Angelo D'Alessandro, Raffaella Di Micco, Alessandro Aiuti, Fabio Ciceri, Giacomo De Luca, Lorenzo Dagna, Marco Matucci-Cerinic, Ivan Merelli, Simone Cenci, Serena Scala, Giulio Cavalli, Luigi Naldini, Samuele Ferrari
Journal: Blood
Blood (2024) 144 (Supplement 1): 4050.
https://doi.org/10.1182/blood-2024-207200
Published: 2024
Journal Articles

Lipid nanoparticles allow efficient and harmless ex vivo gene editing of human hematopoietic cells

Valentina Vavassori, Samuele Ferrari, Stefano Beretta, Claudia Asperti, Luisa Albano, Andrea Annoni, Chiara Gaddoni, Angelica Varesi, Monica Soldi, Alessandro Cuomo, Tiziana Bonaldi, Marina Radrizzani, Ivan Merelli, Luigi Naldini
Journal: Blood
Blood (2023) 142 (9): 812–826.
https://doi.org/10.1182/blood.2022019333
Published: 2023
Includes: Supplemental data
Journal Articles

Liver-Directed Gene Therapy for Hemophilia B with Immune Stealth Lentiviral Vectors

Alessio Cantore, Michela Milani, Andrea Annoni, Tongyao Liu, Sara Bartolaccini, Mauro Biffi, Fabio Russo, Robert Peters, PhD, Angelo Lombardo, Timothy C. Nichols, MD, Eduard Ayuso, Luigi Naldini
Journal: Blood
Blood (2017) 130 (Supplement 1): 605.
https://doi.org/10.1182/blood.V130.Suppl_1.605.605
Published: 2017
Journal Articles

In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance

Andrea Annoni, Brian D. Brown, Alessio Cantore, Lucia Sergi Sergi, Luigi Naldini, Maria-Grazia Roncarolo
Journal: Blood
Blood (2009) 114 (25): 5152–5161.
https://doi.org/10.1182/blood-2009-04-214569
Published: 2009
Journal Articles

A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice

Brian D. Brown, Alessio Cantore, Andrea Annoni, Lucia Sergi Sergi, Angelo Lombardo, Patrizia Della Valle, Armando D'Angelo, Luigi Naldini
Journal: Blood
Blood (2007) 110 (13): 4144–4152.
https://doi.org/10.1182/blood-2007-03-078493
Published: 2007
Includes: Supplemental data
Journal Articles

The immune response to lentiviral-delivered transgene is modulated in vivo by transgene-expressing antigen-presenting cells but not by CD4 + CD25 + regulatory T cells

Andrea Annoni, Manuela Battaglia, Antonia Follenzi, Angelo Lombardo, Lucia Sergi-Sergi, Luigi Naldini, Maria-Grazia Roncarolo
Journal: Blood
Blood (2007) 110 (6): 1788–1796.
https://doi.org/10.1182/blood-2006-11-059873
Published: 2007
Includes: Supplemental data
Journal Articles

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance

Brian D. Brown, Giovanni Sitia, Andrea Annoni, Ehud Hauben, Lucia Sergi Sergi, Anna Zingale, Maria Grazia Roncarolo, Luca G. Guidotti, Luigi Naldini
Journal: Blood
Blood (2006) 109 (7): 2797–2805.
https://doi.org/10.1182/blood-2006-10-049312
Published: 2006
Includes: Supplemental data
Journal Articles

Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice

Antonia Follenzi, Manuela Battaglia, Angelo Lombardo, Andrea Annoni, Maria Grazia Roncarolo, Luigi Naldini
Journal: Blood
Blood (2004) 103 (10): 3700–3709.
https://doi.org/10.1182/blood-2003-09-3217
Published: 2004