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Journal Articles

The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRβ and FIP1L1-PDGFRα in vitro and in vivo

Elizabeth H. Stover, Jing Chen, Benjamin H. Lee, Jan Cools, Elizabeth McDowell, Jennifer Adelsperger, Dana Cullen, Allison Coburn, Sandra A. Moore, Rachel Okabe, Doriano Fabbro, Paul W. Manley, James D. Griffin, D. Gary Gilliland
Journal: Blood
Blood (2005) 106 (9): 3206–3213.
https://doi.org/10.1182/blood-2005-05-1932
Published: 2005
Journal Articles

PKC412 Effectively Inhibits Constitutively Activated FGFR3 Mutants in Murine Leukemia Models and t(4;14) Myeloma Cell Lines.

Jing Chen, Ph.D., Benjamin H. Lee, M.D., Ph.D., Ifor R. Williams, M.D., Ph.D., Jeffery L. Kutok, M.D., Ph.D., Nicole Duclos, Sarah Cohen, Jennifer Adelsperger, Rachel Okabe, Allison Coburn, Sandra Moore, Brian J.P. Huntly, M.D., Ph.D., Constantine S. Mitsiades, M.D., Kenneth C. Anderson, M.D., James D. Griffin, M.D., Doriano Fabbro, Ph.D., D. Gary Gilliland, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2448.
https://doi.org/10.1182/blood.V104.11.2448.2448
Published: 2004
Journal Articles

PKC412 Inhibits the ZNF198-FGFR1 Fusion Tyrosine Kinase and Is Efficacious in Treatment of t(8;13)(p11;q12) Associated Stem Cell Myeloproliferative Disease.

Jing Chen, Ph.D., Daniel J. DeAngelo, M.D., Jeffery L. Kutok, M.D., Ph.D., Ifor R. Williams, M.D., Ph.D., Benjamin H. Lee, M.D., Ph.D., Martha Wadleigh, M.D., Nicole Duclos, Sarah Cohen, Jennifer Adelsperger, Rachel Okabe, Allison Coburn, Ilene Galinsky, Brian J.P. Huntly, M.D., Ph.D., Pamela Cohen, Ph.D., Thomas Meyer, Ph.D., Doriano Fabbro, Ph.D., Lolita Banerji, Ph.D., James D. Griffin, M.D., Sheng Xiao, M.D., Jonathan A. Fletcher, M.D., Richard M. Stone, M.D., D. Gary Gilliland, M.D., Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2549.
https://doi.org/10.1182/blood.V104.11.2549.2549
Published: 2004