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Alexander Hoellein
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Journal Articles

Myc Commands an Aurora Kinase – Sumoylation Circuit Required for B Cell Lymphoma Growth and Survival

Alexander Hoellein, MD, Stephanie Schoeffmann, Fallahi Mohammad, PhD, John L Cleveland, PhD, Johannes Gloeckner, PhD, Marius Ueffing, PhD, Martina Rudelius, MD, Christian Peschel, MD, Ulrich Keller, MD
Journal: Blood
Blood (2014) 124 (21): 3107.
https://doi.org/10.1182/blood.V124.21.3107.3107
Published: 2014
Journal Articles

Myc-induced SUMOylation is a therapeutic vulnerability for B-cell lymphoma

Alexander Hoellein, Mohammad Fallahi, Stephanie Schoeffmann, Sabine Steidle, Franz X. Schaub, Martina Rudelius, Iina Laitinen, Lisa Nilsson, Andrei Goga, Christian Peschel, Jonas A. Nilsson, John L. Cleveland, Ulrich Keller
Journal: Blood
Blood (2014) 124 (13): 2081–2090.
https://doi.org/10.1182/blood-2014-06-584524
Published: 2014
Includes: Supplemental data
Journal Articles

Activated Sumoylation Is a Hallmark Of Burkitt's Lymphoma and MYC Driven Cancer Leading To Synthetic Lethal Interactions With Sumoylation Inhibitors

Alexander Hoellein, MD, Sabine Steidle, MD, Mohammad Fellahi, PhD, Stephanie Schoeffmann, Martina Rudelius, MD, Christian Peschel, John L Cleveland, Ulrich Keller
Journal: Blood
Blood (2013) 122 (21): 3783.
https://doi.org/10.1182/blood.V122.21.3783.3783
Published: 2013
Journal Articles

A case of paroxysmal nocturnal hemoglobinuria caused by a germline mutation and a somatic mutation in PIGT

Brief Report
Peter M. Krawitz, Britta Höchsmann, Yoshiko Murakami, Britta Teubner, Ulrike Krüger, Eva Klopocki, Heidemarie Neitzel, Alexander Hoellein, Christina Schneider, Dmitri Parkhomchuk, Jochen Hecht, Peter N. Robinson, Stefan Mundlos, Taroh Kinoshita, Hubert Schrezenmeier
Journal: Blood
Blood (2013) 122 (7): 1312–1315.
https://doi.org/10.1182/blood-2013-01-481499
Published: 2013
Includes: Supplemental data
Journal Articles

Geminin Is a Newly Identified Cks1 Interaction Partner and Overexpressed in a Murine Model During Lymphomagenesis

Alexander Hoellein, MD, Florian Bassermann, Stephanie Schoeffmann, Steffi Graf, Christian Peschel, MD, Johannes Gloeckner, PhD, Marius Ueffing, PhD, Ulrich Keller, MD
Journal: Blood
Blood (2012) 120 (21): 1328.
https://doi.org/10.1182/blood.V120.21.1328.1328
Published: 2012
Journal Articles

Phase I/II Study of Myeloablative Anti-CD20+ Radioimmunotherapy with I-131-Rituximab in High-Risk CD20-Positive Non Hodgkin Lymphoma

Kathleen Schwarz, MD, Wagner Julia, MD, Susanne Schreiber, MD, Burkhard Schmidt, MD, Alexander Hoellein, MD, Mareike Verbeek, MD, Markus Schwaiger, MD, Christian Peschel, MD, Klemens Scheidhauer, MD, Christoph von Schilling, MD, Ulrich Keller, MD
Journal: Blood
Blood (2012) 120 (21): 3700.
https://doi.org/10.1182/blood.V120.21.3700.3700
Published: 2012
Journal Articles

Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state

Jürgen den Hollander, Sara Rimpi, Joanne R. Doherty, Martina Rudelius, Andreas Buck, Alexander Hoellein, Marcus Kremer, Nikolas Graf, Markus Scheerer, Mark A. Hall, Andrei Goga, Nikolas von Bubnoff, Justus Duyster, Christian Peschel, John L. Cleveland, Jonas A. Nilsson, Ulrich Keller
Journal: Blood
Blood (2010) 116 (9): 1498–1505.
https://doi.org/10.1182/blood-2009-11-251074
Published: 2010
Includes: Supplemental data