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Journal Articles

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53 - or ATM -defective chronic lymphocytic leukemia cells

Marwan Kwok, Nicholas Davies, Angelo Agathanggelou, Edward Smith, Ceri Oldreive, Eva Petermann, Grant Stewart, Jeff Brown, Alan Lau, Guy Pratt, Helen Parry, Malcolm Taylor, Paul Moss, Peter Hillmen, Tatjana Stankovic
Journal: Blood
Blood (2016) 127 (5): 582–595.
https://doi.org/10.1182/blood-2015-05-644872
Published: 2016
Includes: Supplemental data
Journal Articles

ATR Inhibition Exacerbates Replication Stress in TP53 or ATM Deficient CLL Cells and Enhances Sensitivity to Chemotherapy and Targeted Therapy

Marwan Kwok, MB ChB, MRCP, Nicholas Davies, PhD, Angelo Agathanggelou, PhD, Edward Smith, BSc, Eva Petermann, PhD, Eliot Yates, BMedSc, Jeffrey Brown, PhD, Alan Lau, PhD, Tatjana Stankovic, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3340.
https://doi.org/10.1182/blood.V124.21.3340.3340
Published: 2014
Journal Articles

Synthetic Lethality In CLL With DNA Damage Response Defect By Targeting ATR Pathway

Tatjana Stankovic, MD, PhD, Davies Nicholas, Marwan Kwok, Edward Smith, Eliot Yates, Angelo Agathanggelou, Brown Jeff, Alan Lau
Journal: Blood
Blood (2013) 122 (21): 120.
https://doi.org/10.1182/blood.V122.21.120.120
Published: 2013
Journal Articles

A Potential Epigenetic Bookmarking Function for the Hematopoietic Transcription Factor GATA-1.

Stephan Kadauke, Janine M Lamonica, Alan Lau, PhD, Margaret Chou, Ph.D., Gerd Blobel, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2601.
https://doi.org/10.1182/blood.V116.21.2601.2601
Published: 2010
Journal Articles

Enhanced MDR1 Gene Expression in Human T-Cell Leukemia Virus-I–Infected Patients Offers New Prospects for Therapy

Alan Lau, Simon Nightingale, Graham P. Taylor, Timothy W. Gant, Alan J. Cann
Journal: Blood
Blood (1998) 91 (7): 2467–2474.
https://doi.org/10.1182/blood.V91.7.2467
Published: 1998