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Ahmed Abdelbaset-Ismail
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Journal Articles

Novel Evidence That Intracellular Complement Network (complosome) Is Expressed in Hematopoietic Stem Cells (HSPCs) and Regulates Their Trafficking, Metabolism, and Proliferation in an Intracrine-Dependent Manner By Engaging Pattern Recognition Receptor Nlrp3 Inflammasome

Vira Chumak, Andrzej Ciechanowicz, Mateusz Adamiak, Arjun Thapa, Ahmed Abdelbaset-Ismail, Kamila Bujko, Janina Ratajczak, Magda Kucia, Mariusz Z Ratajczak
Journal: Blood
Blood (2022) 140 (Supplement 1): 1987–1988.
https://doi.org/10.1182/blood-2022-158573
Published: 2022
Journal Articles

Novel Evidence That Pineal Gland Hormone Melatonin Inhibits Migration of Hematopoietic Stem/Progenitor Cells (HSPCs) By Inhibiting Nlrp3 Inflammasome and Upregulating Heme Oxygenase-1 (HO-1) - Implications to Understand Better Diurnal Trafficking of HSPCs and Anti-Inflammatory Effects of Melatonin

Ahmed Abdelbaset-Ismail, Arjun Thapa, Janina Ratajczak, Magda Kucia, Mariusz Z Ratajczak
Journal: Blood
Blood (2022) 140 (Supplement 1): 2842–2843.
https://doi.org/10.1182/blood-2022-158581
Published: 2022
Journal Articles

Novel Evidence That NADPH Oxidase 2 (Nox-2) Enhances Trafficking of Hematopoietic Stem Progenitor Cells (HSPCs) By Involving ROS Mediated Activation of Nlrp3 Inflammasome

Kamila Bujko, Mateusz Adamiak, Ahmed Abdelbaset-Ismail, Janina Ratajczak, Magda Kucia, Mariusz Z. Ratajczak
Journal: Blood
Blood (2022) 140 (Supplement 1): 11397.
https://doi.org/10.1182/blood-2022-159672
Published: 2022
Journal Articles

Novel Observation That Trafficking of Hematopoietic Stem Progenitor Cells (HSPCs) Involves Activation of Nlrp3 Inflammasome That Provides Cholesterol and Sphingolipids for the Formation of Lipid Rafts on the Outer Cell Membrane That Are Crucial for Proper Responsiveness of HSPCs to Chemoattractant and Hematopoietic Cytokines/Growth Factors

Andrzej Ciechanowicz, Ahmed Abdelbaset-Ismail, Magda Kucia, Mariusz Z Ratajczak
Journal: Blood
Blood (2022) 140 (Supplement 1): 4470–4471.
https://doi.org/10.1182/blood-2022-158560
Published: 2022
Journal Articles

The Effect of Bioactive Phospholipids on Normal and Malignant Hematopoiesis—Modulation of Their Effects By Downregulating the Activities of Heme Oxygenase 1 (HO-1) and Inducible Nitric Oxygenase Synthase (iNOS)

Ahmed Abdelbaset-Ismail, PhD, Magdalena Kucia, PhD DSci, Janina Ratajczak, MD PhD DSci, Mariusz Z Ratajczak, MD PhD DSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 3803.
https://doi.org/10.1182/blood.V130.Suppl_1.3803.3803
Published: 2017
Journal Articles

Novel Evidence That the Mannan-Binding Lectin (MBL) Pathway of Complement Activation Plays a Pivotal Role in Triggering Mobilization of Hematopoietic Stem/Progenitor Cells By Activation of Both the Complement and Coagulation Cascades

Mateusz Adamiak, Malwina Suszynska, PhD, Ahmed Abdel-Latif, MD PhD, Ahmed Abdelbaset-Ismail, PhD, Janina Ratajczak, MD PhD, Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3371.
https://doi.org/10.1182/blood.V128.22.3371.3371
Published: 2016
Journal Articles

Unexpected Evidence That Inducible Nitric Oxide Synthase (iNOS) Is a Negative Regulator of Hematopoietic Stem/Progenitor Cell Mobilization

Mateusz Adamiak, MS, Ahmed Abdelbaset-Ismail, PhD, Marcin Wysoczynski, PhD, Ahmed Abdel-Latif, MD PhD, Joseph B Moore, IV, MS, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3372.
https://doi.org/10.1182/blood.V128.22.3372.3372
Published: 2016
Journal Articles

Novel Evidence That Hematopoietic-Specific PLC-β2 Is Required for Normal Homing and Engraftment of Hematopoietic Stem Cells

Mateusz Adamiak, MS, Ahmed Abdelbaset Ismail, PhD, Ahmed Abdel-Latif, MD PhD, Janina Ratajczak, MD PhD, Magdalena Kucia, PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3342.
https://doi.org/10.1182/blood.V128.22.3342.3342
Published: 2016
Journal Articles

Heme Oxygenase 1 (HO-1) Is a Novel Negative Regulator of Normal and Malignant Hematopoietic Cell Trafficking

Mateusz Adamiak, MS, Ahmed Abdelbaset-Ismail, PhD, Joseph B Moore, IV, MS, Ahmed Abdel-Latif, MD PhD, Marcin Wysoczynski, PhD, Magdalena Kucia, PhD, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2150.
https://doi.org/10.1182/blood.V128.22.2150.2150
Published: 2016
Journal Articles

Human Hematopoietic Stem/Progenitor Cells (HSPCs) and Mesenchymal Stromal Cells (MSCs) Express Several Functional Pituitary and Gonadal Sex Hormone Receptors - Identification of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) As New Growth Factors for HSPCs and MSCs

Ahmed Abdelbaset-Ismail, PhD, Malwina Suszynska, PhD, Sylwia Julita Borkowska, PhD, Mateusz Adamiak, MS, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2393.
https://doi.org/10.1182/blood.V126.23.2393.2393
Published: 2015
Journal Articles

Novel Evidence That a Lipolytic Enzyme - Hematopoietic-Specific Phospholipase C Beta 2 - Promotes Mobilization of Hematopoietic Stem Cells By Decreasing Their Lipid Raft-Mediated Bone Marrow Retention and Increasing the Pro-Mobilizing Effects of Granulocytes

Mateusz Adamiak, MS, Agata Poniewierska-Baran, PhD, Gabriela Schneider, PhD, Ahmed Abdelbaset-Ismail, PhD, Malwina Suszynska, PhD, Ahmed Abdel-Latif, MD PhD, Magdalena Kucia, PhD, Janina Ratajczak, MD PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1896.
https://doi.org/10.1182/blood.V126.23.1896.1896
Published: 2015
Journal Articles

Transient Ex Vivo Inhibition of Heme Oxygenase 1 (HO-1) in Hematopoietic Stem/Progenitor Cells (HSPCs) By Small-Molecule Inhibitors Enhances Their Migratory Responsiveness to Bone Marrow (BM)-Secreted Chemoattractants a Novel and Simple Strategy to Improve Homing of HSPCs

Mateusz Adamiak, MS, Joseph B Moore IV, PhD, John Zhao, BS, Ahmed Abdelbaset-Ismail, PhD, Marcin Wysoczynski, PhD, Mariusz Z Ratajczak, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4272.
https://doi.org/10.1182/blood.V126.23.4272.4272
Published: 2015