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Journal Articles

Identification of Healthy Donor Phenotypic and Functional Signatures That Predict Allogeneic, Hypoimmune CD19-Directed CAR T Cell Potency

Darin Salloum, Kavita Tundwal, Kwang Bom Choi, Ashley Ranere, Jaclyn Lock, Ben Lam, Jasmin Kristianto, John Yu, Jessica Li, John Lam, Pascal Beauchesne, Allison O'Rourke, Ouwen Liang, Aaron Lampano, Neal van Hoeven, Hosein Kouros-Mehr, Dave Shivak, Weidong Zhang, Tiffany Wan, Lisa Arjes, Christina Chaivorapol, Athena Wong, Adam Johnson, Paul Brunetta, Terry Fry
Journal: Blood
Blood (2023) 142 (Supplement 1): 6810.
https://doi.org/10.1182/blood-2023-188264
Published: 2023
Journal Articles

Hypoimmune, Allogeneic CD22-Directed CAR T Cells That Evade Innate and Adaptive Immune Rejection for the Treatment of Large B Cell Lymphoma Patients That Are Relapsed/Refractory to CD19-Directed CAR T Cell Therapy

Adam Johnson, Hallee Wright, Xiaomeng Hu, Jeremy Kinder, Neal van Hoeven, Ouwen Liang, Brian Granger, Tori Duback, Chris Baldeviano, Sundeep Chandra, Trevor McGill, Boris Gorovits, Shannon Joyce, Sam Crocker, Anna Liang, Carrie Rocca, Jenny Migliaccio, Prasanna Kumar, Vasily Vagin, Kerrie Enger, Chi Young, Andrew McAlister, Sonja Schrepfer, Terry J. Fry
Journal: Blood
Blood (2023) 142 (Supplement 1): 3437.
https://doi.org/10.1182/blood-2023-187096
Published: 2023
Journal Articles

A Dual-Antigen Targeting, Hypoimmune Allogeneic CAR T to Evade Innate and Adaptive Immune Rejection and Overcome Antigen Escape

Adam Johnson, Hallee Wright, Xiaomeng Hu, Neal van Hoeven, PhD, Brian Granger, Ouwen Liang, Jesus Moreno, Meghan Lamba, Chi Young, Andrew McAlister, Terry J. Fry, Sonja Schrepfer, Aaron Foster
Journal: Blood
Blood (2022) 140 (Supplement 1): 4552–4553.
https://doi.org/10.1182/blood-2022-168251
Published: 2022
Journal Articles

Functional T Cell Assays Are Predictive of Pre-Clinical Potency to Generate Allogeneic, Hypoimmune CD19 CAR T Cells

Darin Salloum, PhD, Kavita Tundwal, Divy Kangeyan, PhD, Adam Johnson, Neal van Hoeven, PhD, Brian Granger, Jesus Moreno, Ouwen Liang, Pascal Beauchesne, Terry J. Fry, Aaron Foster
Journal: Blood
Blood (2022) 140 (Supplement 1): 4524–4525.
https://doi.org/10.1182/blood-2022-168372
Published: 2022
Journal Articles

BCMA-Targeted, Hypoimmune Allogeneic CAR T Cells Exhibit Potent Anti-Tumor Activity Together with the Ability to Evade Innate and Adaptive Immune Rejection in Pre-Clinical Tumor Models

Jeremy M. Kinder, Chanel Athena-Estrada, Danyal Malik, Xiaomeng Hu, Meghan Lamba, Chi Young, Neal Van Hoeven, Brian Granger, Vandana Chaturvedi, Ouwen Liang, Jesus Moreno, Aaron Lampano, Garrett Zipp, Adam Johnson, Terry Fry, Sonja Schrepfer, Aaron Foster
Journal: Blood
Blood (2022) 140 (Supplement 1): 7120–7121.
https://doi.org/10.1182/blood-2022-166845
Published: 2022
Journal Articles

CD8-Targeted, Integrating Viral Vectors Transduce Resting T Cells and Enable Extracorporeal Delivery (ECD) for Rapid CAR T Cell Therapies

Jesse Green, Adam Johnson, Brian Granger, Ouwen Liang, Jesus Moreno, Andrew Tucker, Hallee Wright, Brian Dolinski, Hanane Ennajdaoui, Semih Tareen, Neal van Hoeven, PhD, Jagesh Shah, Kutlu Elpek, Aaron Foster, Terry J. Fry
Journal: Blood
Blood (2022) 140 (Supplement 1): 7768–7769.
https://doi.org/10.1182/blood-2022-162705
Published: 2022
Journal Articles

CD4-Targeted Fusosomes Are Capable of Transducing Resting T Helper Cells to Generate Highly Potent CAR-T Cells

Christie Ciarlo, Zach Frye, Andre DeGroot, Walter Flores, Kutlu Elpek, Lauren Pepper, Adam Johnson, Jagesh V Shah, Aaron E. Foster, Terry J. Fry
Journal: Blood
Blood (2021) 138 (Supplement 1): 2942.
https://doi.org/10.1182/blood-2021-148469
Published: 2021
Journal Articles

Novel CD19t T-Antigen Presenting Cells Expand CD19 CAR T Cells In Vivo

Colleen Annesley, MD, Rebecca Gardner, MD, Ashley Wilson, PhD, Corinne Summers, MD, Adam J. Lamble, MD, Julie Rivers, MD, Qian Vicky Wu, PhD, Adam Brand, Adam Johnson, PhD, Karen Spratt, PhD, Stephanie Mgebroff, Christopher Brown, Catherine Lindgren, Julie R. Park, MD, Michael C. Jensen, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 223.
https://doi.org/10.1182/blood-2019-131346
Published: 2019
Journal Articles

Novel CD19t T-Antigen Presenting Cells Designed to Re-Activate and Expand CD19 CAR T Cells In Vivo: Early Demonstration of Feasibility and Safety

Colleen Annesley, MD, Rebecca Gardner, MD, Olivia Finney, PhD, Corinne Summers, MD, Adam J. Lamble, MD, Julie Rivers, MD, Adam Johnson, PhD, Karen Spratt, PhD, Stephanie Mgebroff, Christopher Brown, Catherine Lindgren, Julie R. Park, MD, Michael C. Jensen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4021.
https://doi.org/10.1182/blood-2018-99-112285
Published: 2018
Journal Articles

Early Clinical Experience of CD19 x CD22 Dual Specific CAR T Cells for Enhanced Anti-Leukemic Targeting of Acute Lymphoblastic Leukemia

Rebecca Gardner, MD, Colleen Annesley, MD, Olivia Finney, PhD, Corinne Summers, MD, Adam J. Lamble, MD, Julie Rivers, MD, Kaelin Crews, Lauren Huang, Christopher Brown, Stephanie Mgebroff, Catherine Lindgren, Karen Spratt, PhD, Josh Gustafson, PhD, Adam Johnson, PhD, Julie R. Park, MD, Michael C. Jensen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 278.
https://doi.org/10.1182/blood-2018-99-113126
Published: 2018