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Adam C Straub
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Journal Articles

Daprodustat Induces Fetal Hemoglobin and Erythropoietic Drive in an in Vitro and In Vivo Model of Sickle Cell Disease

Malini Sharma, Fabliha Ahmed Chowdhury, Stefanie Taiclet, Brian J Philips, Katherine C Wood, Adam C Straub, Julia Xu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1111.
https://doi.org/10.1182/blood-2024-209205
Published: 2024
Journal Articles

Higher Hemoglobin Level Correlates with Increased Tissue Oxygenation in a Comprehensive Profile of Hemorheology in Sickle Cell Disease

Christine Saber, Elizabeth Meinert-Spyker, Lara Abdelmohsen, Brian J Philips, Joel Dzidzorvi Kwame Disu, Nahom Mossazghi, Nelly Kiriza, Seyed Mehdi Nouraie, Olubusola Oluwole, Laura M. DeCastro, Adam C Straub, Enrico M Novelli, Sossena Wood, Julia Xu
Journal: Blood
Blood (2024) 144 (Supplement 1): 294.
https://doi.org/10.1182/blood-2024-203346
Published: 2024
Journal Articles

Role of CYB5R3 in Erythropoiesis-Associated Heme Biosynthesis

Fabliha Ahmed Chowdhury, Malini Sharma, Katherine C Wood, Megan P Miller, Shuai Yuan, Adam C Straub
Journal: Blood
Blood (2024) 144 (Supplement 1): 2471.
https://doi.org/10.1182/blood-2024-198248
Published: 2024
Journal Articles

Obesity-Induced Platelet Mitofusin-1 Expression Causes Vascular Dysfunction

Gowtham K Annarapu, Stefanie Taiclet, Scott Hahn, Deirdre Nolfi-Donegan, Michael Jurczak, Adam C Straub, Sruti Shiva
Journal: Blood
Blood (2023) 142 (Supplement 1): 2571.
https://doi.org/10.1182/blood-2023-187693
Published: 2023
Journal Articles

Inhibition of Hypoxia Inducible Factor Prolyl Hydroxylase By FG-4592 (Roxadustat) Increases Erythropoietic Stimulation in a Mouse Model of Sickle Cell Disease

Malini Sharma, Timothy Lequang, Brian J Philips, Fabliha A Chowdhury, Katherine C Wood, Adam C Straub, Julia Z Xu
Journal: Blood
Blood (2022) 140 (Supplement 1): 5391–5392.
https://doi.org/10.1182/blood-2022-164803
Published: 2022
Journal Articles

Preclinical Development and Screening of a Quinone-Nitroalkene Molecule for Sickle Cell Anemia

Fabliha A Chowdhury, Megan P Miller, Katherine C Wood, Malini Sharma, Shuai Yuan, Stefanie N Taiclet, Derek J Sinchar, Elizabeth R Rochon, Francisco J Schopfer, Bruce A Freeman, Adam C Straub
Journal: Blood
Blood (2022) 140 (Supplement 1): 957–958.
https://doi.org/10.1182/blood-2022-160188
Published: 2022
Journal Articles

Loss of Cyb5R3 Function Silences Fetal Hemoglobin and Hematocrit Responses to Hydroxyurea in Patients with Sickle Cell Anemia

Katherine C Wood, Fabliha A Chowdhury, Seyed M Nouraie, Mark T. Gladwin, Adam C Straub
Journal: Blood
Blood (2022) 140 (Supplement 1): 455–456.
https://doi.org/10.1182/blood-2022-165388
Published: 2022
Journal Articles

SOD2 V16A amplifies vascular dysfunction in sickle cell patients by curtailing mitochondria complex IV activity

Brief Report
Atinuke Dosunmu-Ogunbi, Shuai Yuan, Michael Reynolds, Luca Giordano, Subramaniam Sanker, Mara Sullivan, Donna Beer Stolz, Brett A. Kaufman, Katherine C. Wood, Yingze Zhang, Sruti Shiva, Seyed Mehdi Nouraie, Adam C. Straub
Journal: Blood
Blood (2022) 139 (11): 1760–1765.
https://doi.org/10.1182/blood.2021013350
Published: 2022
Includes: Supplemental data
Journal Articles

The Role of Endothelial Superoxide Dismutase 2 in Modulating Sickle Pathology

Atinuke Dosunmu-Ogunbi, Shuai Yuan, Adam C Straub
Journal: Blood
Blood (2021) 138 (Supplement 1): 190.
https://doi.org/10.1182/blood-2021-152988
Published: 2021
Journal Articles

Xanthine Oxidase Has a Protective Role during Heme Crisis By Binding and Degrading Heme

Heidi M Schmidt, Scott Hahn, MS, Gowtham K Annarapu, PhD, Mara Carreño, Francisco Schopfer, Sruti Shiva, PhD, Dario A. Vitturi, PhD, Eric Kelley, PhD, Adam C Straub, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12.
https://doi.org/10.1182/blood-2020-137185
Published: 2020
Journal Articles

The T117S Variant of Cytochrome b5 Reductase 3 Increases the Risk for Ischemic Stroke with Enhanced Anemia in Mice with Sickle Cell Disease

Katherine C Wood, PhD, Heidi M Schmidt, Scott Hahn, MS, Subramaniam Sanker, PhD, Samit Ghosh, PhD, Solomon Fiifi Ofori-Acquah, PhD, Seyed Mehdi Nouraie, MD PhD, Mark T Gladwin, MD, Adam C Straub, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-142076
Published: 2020
Journal Articles

Nrf2 Activation Attenuates Hemolysis but Promotes Pulmonary Vascular Dysfunction in Sickle Mice

Chibueze A. Ihunnah, PhD, Samit Ghosh, PhD, Scott A. Hahn, MS, Adam C Straub, PhD, Solomon F Ofori-Acquah, PhD
Journal: Blood
Blood (2016) 128 (22): 1296.
https://doi.org/10.1182/blood.V128.22.1296.1296
Published: 2016