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Brian J Philips
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Journal Articles

Daprodustat Induces Fetal Hemoglobin and Erythropoietic Drive in an in Vitro and In Vivo Model of Sickle Cell Disease

Malini Sharma, Fabliha Ahmed Chowdhury, Stefanie Taiclet, Brian J Philips, Katherine C Wood, Adam C Straub, Julia Xu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1111.
https://doi.org/10.1182/blood-2024-209205
Published: 2024
Journal Articles

Higher Hemoglobin Level Correlates with Increased Tissue Oxygenation in a Comprehensive Profile of Hemorheology in Sickle Cell Disease

Christine Saber, Elizabeth Meinert-Spyker, Lara Abdelmohsen, Brian J Philips, Joel Dzidzorvi Kwame Disu, Nahom Mossazghi, Nelly Kiriza, Seyed Mehdi Nouraie, Olubusola Oluwole, Laura M. DeCastro, Adam C Straub, Enrico M Novelli, Sossena Wood, Julia Xu
Journal: Blood
Blood (2024) 144 (Supplement 1): 294.
https://doi.org/10.1182/blood-2024-203346
Published: 2024
Journal Articles

A Phase 1b/2 Study of the Efficacy and Safety of Combination Hydroxyurea and Dose-Escalated Erythropoietin for Treatment of Anemia in Sickle Cell Disease (ACHiEvE-SCD)

Titilope A Adeyemo, Nelly Kiriza, Feyisayo T. Oluwole, Mark Jelinek, Jude Jonassaint, Olubusola Oluwole, Christine Saber, Brian J Philips, Olusegun-Joseph D Akinsanya, Vincent O Osunkalu, Laura M. DeCastro, Enrico M Novelli, Julia Z Xu
Journal: Blood
Blood (2024) 144 (Supplement 1): 178.
https://doi.org/10.1182/blood-2024-205261
Published: 2024
Journal Articles

Inhibition of Purine Nucleoside Phosphorylase Is a Promising Anti-Sickling Approach for Sickle Cell Disease

Adekunle Emmanuel Alagbe, Lynda Little-Ihrig, Brian J Philips, Stephanie M Mutchler, Julia Z Xu, Edwin K Jackson, Stevan Tofovic, Enrico M Novelli
Journal: Blood
Blood (2024) 144 (Supplement 1): 3861.
https://doi.org/10.1182/blood-2024-199595
Published: 2024
Journal Articles

Inhibition of Hypoxia Inducible Factor Prolyl Hydroxylase By FG-4592 (Roxadustat) Increases Erythropoietic Stimulation in a Mouse Model of Sickle Cell Disease

Malini Sharma, Timothy Lequang, Brian J Philips, Fabliha A Chowdhury, Katherine C Wood, Adam C Straub, Julia Z Xu
Journal: Blood
Blood (2022) 140 (Supplement 1): 5391–5392.
https://doi.org/10.1182/blood-2022-164803
Published: 2022