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Journal Articles

AML typical mutations ( CEBPA , FLT3 , NPM1 ) identify a high-risk chronic myelomonocytic leukemia independent of CPSS molecular

Clinical Trials & Observations
Sandra Castaño-Díez, Mònica López-Guerra, Inés Zugasti, Xavier Calvo, Felicitas Isabel Schulz, Alejandro Avendaño, Elvira Mora, José Falantes, Gemma Azaceta, Mariam Ibáñez, Tzu Chen, Cristina Notario, Neus Amer, Laura Palomo, Helena Pomares, Jordi Vila, Teresa Bernal del Castillo, Carlos Jiménez-Vicente, Daniel Esteban, Francesca Guijarro, José Álamo, Albert Cortés-Bullich, Víctor Torrecillas-Mayayo, Ana Triguero, Lucía Mont-de Torres, Ester Carcelero, Aina Cardús, Ulrich Germing, Beate Betz, Maria Rozman, Leonor Arenillas, Lurdes Zamora, María Díez-Campelo, Blanca Xicoy, Jordi Esteve, Marina Díaz-Beyá
Journal: Blood Advances
Blood Adv (2025) 9 (1): 39–53.
https://doi.org/10.1182/bloodadvances.2024013648
Published: 2025
Includes: Supplemental data
Journal Articles

CD37 in acute myeloid leukemia: a novel surface target for drug delivery

Erin Jeremy, Esthela Artiga, Sara Elgamal, Carolyn Cheney, Dalen Eicher, Kevan Zalponik, Shelley Orwick, Charlene Mao, Ronni Wasmuth, Bonnie Harrington, Allison Mustonen, Peter Beshay, Patrick Halley, Carlos Castro, Katie Williams, Zachary Hing, Timothy Chen, Christopher Lucas, Nicholas J. Vantangoli, Rosa Lapalombella, Nicole Grieselhuber, Xiaokui Mo, Erin Hertlein, Natarajan Muthusamy, Bethany L. Mundy-Bosse, John C. Byrd, Karilyn T. Larkin
Journal: Blood Advances
Blood Adv (2025) 9 (1): 1–14.
https://doi.org/10.1182/bloodadvances.2024013590
Published: 2025
Includes: Supplemental data
Journal Articles

Development of iPSC-derived human bone marrow organoid for autonomous hematopoiesis and patient-derived HSPC engraftment

Kehan Ren, Ermin Li, Inci Aydemir, Yijie Liu, Xu Han, Honghao Bi, Pan Wang, Kara Tao, Amy Ji, Yi-Hua Chen, Jing Yang, Madina Sukhanova, Peng Ji
Journal: Blood Advances
Blood Adv (2025) 9 (1): 54–65.
https://doi.org/10.1182/bloodadvances.2024013361
Published: 2025
Includes: Supplemental data
Journal Articles

Genome-wide CRISPR screen identifies AraC-Dauno-Eto (ADE) response modulators that predicts outcome in pediatric AML

Nam HK Nguyen, Roya Rafiee, Phani Krishan Parcha, Abderrahmane Tagmount, Jeffrey Rubnitz, Raul C. Ribeiro, Xueyuan Cao, Stanley B Pounds, Christopher D Vulpe, Jatinder Kaur Lamba
Journal: Blood Advances
Blood Adv bloodadvances.2024014157.
https://doi.org/10.1182/bloodadvances.2024014157
Published: 2024
Includes: Supplemental data
Journal Articles

G3BP1::CSF1R: a new and actionable gene fusion in acute megakaryoblastic leukemia

Xi Luo, Chi Keung Cheng, Hoi-Yun Chan, Kam Tong Leung, Chi-kong Li, Yuk-Fei Chung, Herbert Augustus Pitts, Ke Tian, Yuet-Fong Kam, Margaret Heung Ling Ng
Journal: Blood Advances
Blood Adv bloodadvances.2024014354.
https://doi.org/10.1182/bloodadvances.2024014354
Published: 2024
Includes: Supplemental data
Journal Articles

Double mutant DNMT3A AML: a unique subtype experiencing increased DNA damage and poor prognosis

Emma L. Boertjes, Sanne Massaar, Annelieke Zeilemaker, Jolinda Konijnenburg, Melissa Rijken, François G. Kavelaars, Tim Grob, Jurjen Versluis, Bob Löwenberg, Peter J.M. Valk, Mathijs Arnoud Sanders
Journal: Blood Advances
Blood Adv bloodadvances.2024014698.
https://doi.org/10.1182/bloodadvances.2024014698
Published: 2024
Includes: Supplemental data
Journal Articles

Lower-intensity CPX-351 plus venetoclax induction for adults with newly diagnosed AML unfit for intensive chemotherapy

Clinical Trials & Observations
Geoffrey L. Uy, Vinod Pullarkat, Praneeth Baratam, Robert K. Stuart, Roland B. Walter, Eric S. Winer, Qi Wang, Stefan Faderl, Divya Chakravarthy, Diane Menno, Ronald S. Cheung, Tara L. Lin
Journal: Blood Advances
Blood Adv (2024) 8 (24): 6248–6256.
https://doi.org/10.1182/bloodadvances.2024013687
Published: 2024
Includes: Supplemental data
Journal Articles

Identification of factors predicting low-risk febrile neutropenia admissions in adults with acute myeloid leukemia

Khushboo V. Pal, Megan Othus, Zahra Ali, Katherine Russell, Carole Shaw, Mary-Elizabeth M. Percival, Paul C. Hendrie, Jacob S. Appelbaum, Roland B. Walter, Anna B. Halpern
Journal: Blood Advances
Blood Adv (2024) 8 (24): 6161–6170.
https://doi.org/10.1182/bloodadvances.2024014291
Published: 2024
Includes: Supplemental data
Journal Articles

JAK2 p.R564 germ line variants associated with hereditary thrombocythemia and hematologic neoplasms

Brittany L Stewart, Hetty E Carraway, Adriana L Alvarez, Harry Lesmana, John C Molina, Zheng Jin Tu, David S Bosler, Aaron T. Gerds, Babal K Jha, Emilia Calvaresi, Joy Nakitandwe, Abhay Singh
Journal: Blood Advances
Blood Adv bloodadvances.2024013661.
https://doi.org/10.1182/bloodadvances.2024013661
Published: 2024
Journal Articles

Risk of bleeding in patients with essential thrombocythemia and extreme thrombocytosis

Rathnam K. Venkat, Robert A. Redd, Amyah C. Harris, Martin J. Aryee, Anna E. Marneth, Baransel Kamaz, Chulwoo J. Kim, Mohammed Wazir, Lachelle D. Weeks, Maximilian Stahl, Daniel J. DeAngelo, R. Coleman Lindsley, Marlise R. Luskin, Gabriela S. Hobbs, Joan How
Journal: Blood Advances
Blood Adv (2024) 8 (23): 6043–6054.
https://doi.org/10.1182/bloodadvances.2024013777
Published: 2024
Includes: Supplemental data
Journal Articles

Advantages of a genomic DNA-based NGS assay for detection of mutant NPM1 measurable residual disease in AML

Christian M Vonk, Tim Grob, Melissa Rijken, François G. Kavelaars, Jolinda Konijnenburg, Gert J Ossenkoppele, Markus G. Manz, Yngvar Floisand, Bob Löwenberg, Peter J.M. Valk
Journal: Blood Advances
Blood Adv bloodadvances.2024014490.
https://doi.org/10.1182/bloodadvances.2024014490
Published: 2024
Includes: Supplemental data
Journal Articles

Venetoclax-Proteasome inhibitor-Dexamethasone for unfit patients with Blastic Plasmacytoid Dendritic Cell Neoplasm

Sabine Khalife-Hachem, Arnaud Pages, Elie Akoury, Sarah Bonnet, Rudy Birsen, Clemence Busquet, Adrien Contejean, Alina Danu, Stéphane De Botton, Marie De Charette, Pierre-Yves Dumas, Arnaud Jaccard, Anne Marfaing-Koka, Christophe Willekens, Eric Deconinck, David Ghez
Journal: Blood Advances
Blood Adv bloodadvances.2024014590.
https://doi.org/10.1182/bloodadvances.2024014590
Published: 2024
Journal Articles

Impact of Measurable Residual Disease Clearance Kinetics in Patients with AML Undergoing Intensive Chemotherapy

Wei Ying Jen, Koji Sasaki, Farhad Ravandi, Tapan M. Kadia, Sa A. Wang, Wei Wang, Sanam Loghavi, Naval G. Daver, Courtney D. DiNardo, Ghayas C. Issa, Hussein A. Abbas, Cedric Nasnas, Alex Bataller, Samuel Urrutia, Omer S. Karrar, Sherry A Pierce, Hagop M Kantarjian, Nicholas J. Short
Journal: Blood Advances
Blood Adv bloodadvances.2024013826.
https://doi.org/10.1182/bloodadvances.2024013826
Published: 2024
Includes: Supplemental data
Journal Articles

Anxiety and Depression in Patients with Histiocytic Neoplasms and their Associated Clinical Features

Anne S. Reiner, Yesne Alici, Denise D Correa, Dana Bossert, Allison M Sigler, Deanna Fournier, Kathleen Brewer, Gaurav Goyal, Thomas M Atkinson, Priya H Marathe, Jun Mao, Katherine S Panageas, Eli L Diamond
Journal: Blood Advances
Blood Adv bloodadvances.2024014850.
https://doi.org/10.1182/bloodadvances.2024014850
Published: 2024
Includes: Supplemental data
Journal Articles

TIFAB Modulates Metabolic Pathways in KMT2A::MLLT3-Induced AML Through HNF4A

Yang Wang, Yan Xiu, Qianze Dong, Jinming Zhao, Kelao Neumbo, Masaru Miyagi, Nicholas Borcherding, Lin Fu, Havana Ray De Celis, Nicolas Giuseppe Pintozzi, Daniel T Starczynowski, Chen Zhao
Journal: Blood Advances
Blood Adv bloodadvances.2024013446.
https://doi.org/10.1182/bloodadvances.2024013446
Published: 2024
Includes: Supplemental data
Journal Articles

Measurable residual disease monitoring in AML with FLT3 -ITD treated with intensive chemotherapy plus midostaurin

Frank G. Rücker, Lars Bullinger, Sibylle Cocciardi, Sabrina Skambraks, Tamara J. Luck, Daniela Weber, Julia Krzykalla, Ema Pozek, Isabelle Schneider, Andrea Corbacioglu, Verena I. Gaidzik, Annika Meid, Sophia Aicher, Frank Stegelmann, Anika Schrade, Frauke Theis, Walter Fiedler, Helmut R. Salih, Gerald Wulf, Hans Salwender, Thomas Schroeder, Katharina S. Götze, Michael W. M. Kühn, Michael Lübbert, Richard F. Schlenk, Axel Benner, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Konstanze Döhner
Journal: Blood Advances
Blood Adv (2024) 8 (23): 6067–6080.
https://doi.org/10.1182/bloodadvances.2024013758
Published: 2024
Includes: Supplemental data
Journal Articles

RAPID-CRISPR: Highly Sensitive Diagnostic Assay for Detection of PML-RARA Isoforms in Acute Promyelocytic Leukemia

Akash Maity, Amritha Sathyanarayanan, Rohit Kumar, Jesal Vora, Jitendra Gawde, Hasmukh Jain, Dr., Bhausaheb Bagal, Papagudi G Subramanian, Manju Sengar, MD, DM, Navin Khattry, Nikhil Patkar, Syed Khizer Hasan
Journal: Blood Advances
Blood Adv bloodadvances.2024014539.
https://doi.org/10.1182/bloodadvances.2024014539
Published: 2024
Includes: Supplemental data
Journal Articles

Diabetes mellitus, metformin, and the risk of MPN

Ivan Krecak, Sanja Klobucar, Josipa Budimir, Marko Skelin, Marko Lucijanic
Journal: Blood Advances
Blood Adv (2024) 8 (22): 5929–5931.
https://doi.org/10.1182/bloodadvances.2024013772
Published: 2024
Journal Articles

The use of metformin and risk of myeloproliferative neoplasms among patients with no registered markers of diabetes

Clinical Trials & Observations
Daniel Tuyet Kristensen, Andreas Kiesbye Øvlisen, Tarec Christoffer El-Galaly, Anne Stidsholt Roug
Journal: Blood Advances
Blood Adv (2024) 8 (22): 5932–5934.
https://doi.org/10.1182/bloodadvances.2024014173
Published: 2024
Journal Articles

Chronic Inflammation Deters Natural Killer Cell Fitness and Cytotoxicity in Myeloid Leukemia

Valeriya Kuznetsova, Vaidehi Krishnan, Amanda Costa, Xi Ren, Tiffany D. Ricketts, Sweta B Patel, Ashley N Connelly, Paran Goel, Joshua P Knapp, Alana M. Franceski, Francesca Luca, Lorena Lobo de Figueiredo-Pontes, Ravi Bhatia, Shyam Prabhakar, S. Tiong Ong, Robert S. Welner
Journal: Blood Advances
Blood Adv bloodadvances.2024014592.
https://doi.org/10.1182/bloodadvances.2024014592
Published: 2024
Includes: Supplemental data