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Journal Articles

CRISPR-edited megakaryocytes for rapid screening of platelet gene functions

Emilie Montenont, Seema Bhatlekar, Shancy Jacob, Yasuhiro Kosaka, Bhanu K. Manne, Olivia Lee, Ivan Parra-Izquierdo, Emilia Tugolukova, Neal D. Tolley, Matthew T. Rondina, Paul F. Bray, Jesse W. Rowley
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2362–2374.
https://doi.org/10.1182/bloodadvances.2020004112
Published: 2021
Includes: Supplemental data
Journal Articles

Transfer to the clinic: refining forward programming of hPSCs to megakaryocytes for platelet production in bioreactors

Amanda L. Evans, Amanda Dalby, Holly R. Foster, Daniel Howard, Amie K. Waller, Momal Taimoor, Moyra Lawrence, Souradip Mookerjee, Marcus Lehmann, Annie Burton, Jorge Valdez, Jonathan Thon, Joseph Italiano, Thomas Moreau, Cedric Ghevaert
Journal: Blood Advances
Blood Adv (2021) 5 (7): 1977–1990.
https://doi.org/10.1182/bloodadvances.2020003236
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Platelet-derived extracellular vesicles infiltrate and modify the bone marrow during inflammation

Shauna L. French, Kirill R. Butov, Isabelle Allaeys, Jorge Canas, Golnaz Morad, Patricia Davenport, Audrée Laroche, Natalia M. Trubina, Joseph E. Italiano, Jr., Marsha A. Moses, Martha Sola-Visner, Eric Boilard, Mikhail A. Panteleev, Kellie R. Machlus
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3011–3023.
https://doi.org/10.1182/bloodadvances.2020001758
Published: 2020
Includes: Supplemental data
Journal Articles

Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1

Isabelle C. Becker, Inga Scheller, Lou M. Wackerbarth, Sarah Beck, Tobias Heib, Katja Aurbach, Georgi Manukjan, Carina Gross, Markus Spindler, Zoltan Nagy, Walter Witke, Pekka Lappalainen, Markus Bender, Harald Schulze, Irina Pleines, Bernhard Nieswandt
Journal: Blood Advances
Blood Adv (2020) 4 (10): 2124–2134.
https://doi.org/10.1182/bloodadvances.2019001303
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensing

Hira Niazi, Nesrine Zoghdani, Ludovic Couty, Alexandre Leuci, Anja Nitzsche, Maria L. Allende, Boubacar Mariko, Rameez Ishaq, Yetki Aslan, Pierre Hadrien Becker, Salomé L. Gazit, Sonia Poirault-Chassac, Benoit Decouture, Veronique Baudrie, Erica De Candia, Mari Kono, Ammar Benarab, Pascale Gaussem, Pierre-Louis Tharaux, Jerold Chun, Sylvain Provot, Najet Debili, Patrice Therond, Richard L. Proia, Christilla Bachelot-Loza, Eric Camerer
Journal: Blood Advances
Blood Adv (2019) 3 (11): 1702–1713.
https://doi.org/10.1182/bloodadvances.2019031948
Published: 2019
Includes: Supplemental data
Journal Articles

Dysregulated megakaryocyte distribution associated with nestin + mesenchymal stem cells in immune thrombocytopenia

Min Wang, Ru Feng, Jia-min Zhang, Lin-lin Xu, Fei-er Feng, Chen-cong Wang, Qian-ming Wang, Xiao-lu Zhu, Yun He, Jing Xue, Hai-xia Fu, Meng Lv, Yuan Kong, Ying-jun Chang, Lan-ping Xu, Kai-yan Liu, Xiao-jun Huang, Xiao-hui Zhang
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1416–1428.
https://doi.org/10.1182/bloodadvances.2018026690
Published: 2019
Includes: Supplemental data
Journal Articles

Infused factor VIII–expressing platelets or megakaryocytes as a novel therapeutic strategy for hemophilia A

Randolph B. Lyde, Hyun Sook Ahn, Karen K. Vo, Danuta J. Jarocha, John Tkaczynski, Elsa Treffeisen, Spencer K. Sullivan, Rodney M. Camire, Denise E. Sabatino, Deborah L. French, Mortimer Poncz
Journal: Blood Advances
Blood Adv (2019) 3 (9): 1368–1378.
https://doi.org/10.1182/bloodadvances.2017007914
Published: 2019
Includes: Supplemental data
Journal Articles

Dynamins 2 and 3 control the migration of human megakaryocytes by regulating CXCR4 surface expression and ITGB1 activity

Praveen K. Suraneni, Seth J. Corey, Michael J. Hession, Rameez Ishaq, Arinola Awomolo, Shirin Hasan, Chirag Shah, Hui Liu, Amittha Wickrema, Najet Debili, John D. Crispino, Elizabeth A. Eklund, Yolande Chen
Journal: Blood Advances
Blood Adv (2018) 2 (23): 3540–3552.
https://doi.org/10.1182/bloodadvances.2018021923
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

A unique microenvironment in the developing liver supports the expansion of megakaryocyte progenitors

Nathalie Brouard, Camille Jost, Nadine Matthias, Camille Albrecht, Sébastien Egard, Poojabahen Gandhi, Catherine Strassel, Tomoko Inoue, Daisuke Sugiyama, Paul J. Simmons, Christian Gachet, Francois Lanza
Journal: Blood Advances
Blood Adv (2017) 1 (21): 1854–1866.
https://doi.org/10.1182/bloodadvances.2016003541
Published: 2017
Includes: Supplemental data
Journal Articles

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets

Anne Zufferey, Edwin R. Speck, Kellie R. Machlus, Rukhsana Aslam, Li Guo, Mark J. McVey, Michael Kim, Rick Kapur, Eric Boilard, Joseph E. Italiano, Jr, John W. Semple
Journal: Blood Advances
Blood Adv (2017) 1 (20): 1773–1785.
https://doi.org/10.1182/bloodadvances.2017007021
Published: 2017
Includes: Supplemental data
Journal Articles

Platelet dense granules begin to selectively accumulate mepacrine during proplatelet formation

Hayley A. Hanby, Jialing Bao, Ji-Yoon Noh, Danuta Jarocha, Mortimer Poncz, Mitchell J. Weiss, Michael S. Marks
Journal: Blood Advances
Blood Adv (2017) 1 (19): 1478–1490.
https://doi.org/10.1182/bloodadvances.2017006726
Published: 2017
Includes: Supplemental data
Journal Articles

Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells

Ayako Aihara, Tomo Koike, Natsuki Abe, Sou Nakamura, Akira Sawaguchi, Takanori Nakamura, Naoshi Sugimoto, Hiromitsu Nakauchi, Taito Nishino, Koji Eto
Journal: Blood Advances
Blood Adv (2017) 1 (7): 468–476.
https://doi.org/10.1182/bloodadvances.2016000844
Published: 2017
Includes: Supplemental data