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Journal Articles

Comprehensive CRISPR-Cas9 screens identify genetic determinants of drug responsiveness in multiple myeloma

Stephan R. Bohl, Laura K. Schmalbrock, Imke Bauhuf, Tatjana Meyer, Anna Dolnik, Martin Szyska, Tamara J. Blätte, Sarah Knödler, Linda Röhner, Denise Miller, Miriam Kull, Christian Langer, Hartmut Döhner, Anthony Letai, Frederik Damm, Dirk Heckl, Lars Bullinger, Jan Krönke
Journal: Blood Advances
Blood Adv (2021) 5 (9): 2391–2402.
https://doi.org/10.1182/bloodadvances.2020003541
Published: 2021
Includes: Supplemental data
Journal Articles

Genome-wide interference of ZNF423 with B-lineage transcriptional circuitries in acute lymphoblastic leukemia

Pablo Iglesias, Ann-Christin Puller, Marcos Seoane, Michael Spohn, Sabine Raasch, Marianne Klokow, Jürgen Müller, Lia Burkhardt, Daniela Indenbirken, Martin A. Horstmann
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1209–1223.
https://doi.org/10.1182/bloodadvances.2020001844
Published: 2021
Includes: Supplemental data
Journal Articles

Large-scale GMP-compliant CRISPR-Cas9–mediated deletion of the glucocorticoid receptor in multivirus-specific T cells

Rafet Basar, May Daher, Nadima Uprety, Elif Gokdemir, Abdullah Alsuliman, Emily Ensley, Gonca Ozcan, Mayela Mendt, Mayra Hernandez Sanabria, Lucila Nassif Kerbauy, Ana Karen Nunez Cortes, Li Li, Pinaki P. Banerjee, Luis Muniz-Feliciano, Sunil Acharya, Natalie W. Fowlkes, Junjun Lu, Sufang Li, Stephan Mielke, Mecit Kaplan, Vandana Nandivada, Mustafa Bdaiwi, Alexander D. Kontoyiannis, Ye Li, Enli Liu, Sonny Ang, David Marin, Lorenzo Brunetti, Michael C. Gundry, Rolf Turk, Mollie S. Schubert, Garrett R. Rettig, Matthew S. McNeill, Gavin Kurgan, Mark A. Behlke, Richard Champlin, Elizabeth J. Shpall, Katayoun Rezvani
Journal: Blood Advances
Blood Adv (2020) 4 (14): 3357–3367.
https://doi.org/10.1182/bloodadvances.2020001977
Published: 2020
Includes: Supplemental data
Journal Articles

The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells

Xianjiang Lan, Eugene Khandros, Peng Huang, Scott A. Peslak, Saurabh K. Bhardwaj, Jeremy D. Grevet, Osheiza Abdulmalik, Hongxin Wang, Cheryl A. Keller, Belinda Giardine, Josue Baeza, Emily R. Duffner, Osama El Demerdash, Xiaoli S. Wu, Christopher R. Vakoc, Benjamin A. Garcia, Ross C. Hardison, Junwei Shi, Gerd A. Blobel
Journal: Blood Advances
Blood Adv (2019) 3 (10): 1586–1597.
https://doi.org/10.1182/bloodadvances.2019032318
Published: 2019
Includes: Supplemental data
Journal Articles

Gene editing rescue of a novel MPL mutant associated with congenital amegakaryocytic thrombocytopenia

Cédric Cleyrat, Romain Girard, Eun H. Choi, Éric Jeziorski, Thierry Lavabre-Bertrand, Sylvie Hermouet, Serge Carillo, Bridget S. Wilson
Journal: Blood Advances
Blood Adv (2017) 1 (21): 1815–1826.
https://doi.org/10.1182/bloodadvances.2016002915
Published: 2017
Includes: Supplemental data
Journal Articles

Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells

Erik Pittermann, Nico Lachmann, Glenn MacLean, Stephan Emmrich, Mania Ackermann, Gudrun Göhring, Brigitte Schlegelberger, Karl Welte, Axel Schambach, Dirk Heckl, Stuart H. Orkin, Tobias Cantz, Jan-Henning Klusmann
Journal: Blood Advances
Blood Adv (2017) 1 (14): 903–914.
https://doi.org/10.1182/bloodadvances.2016003798
Published: 2017
Includes: Supplemental data