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Journal Articles

Systemic bevacizumab for refractory bleeding and transfusion-dependent anemia in Heyde syndrome

Clinical Trials & Observations
Andrew B. Song, Rahul Sakhuja, Nancy M. Gracin, Ronald Weinger, Raj S. Kasthuri, Hanny Al-Samkari
Journal: Blood Advances
Blood Adv (2021) 5 (19): 3850–3854.
https://doi.org/10.1182/bloodadvances.2021004810
Published: 2021
Journal Articles

Canonical Wnt: a safeguard and threat for erythropoiesis

Rosa A. Krimpenfort, Micha Nethe
Journal: Blood Advances
Blood Adv (2021) 5 (18): 3726–3735.
https://doi.org/10.1182/bloodadvances.2021004845
Published: 2021
Journal Articles

Peripheral blood cytopenias in the aging general population and risk of incident hematological disease and mortality

Clinical Trials & Observations
Isabelle A. van Zeventer, Aniek O. de Graaf, Melanie M. van der Klauw, Edo Vellenga, Bert A. van der Reijden, Jan Jacob Schuringa, Arjan Diepstra, Luca Malcovati, Joop H. Jansen, Gerwin Huls
Journal: Blood Advances
Blood Adv (2021) 5 (17): 3266–3278.
https://doi.org/10.1182/bloodadvances.2021004355
Published: 2021
Includes: Supplemental data
Journal Articles

Final results of a phase 2 clinical trial of LCL161, an oral SMAC mimetic for patients with myelofibrosis

Clinical Trials & Observations
Naveen Pemmaraju, Bing Z. Carter, Prithviraj Bose, Nitin Jain, Tapan M. Kadia, Guillermo Garcia-Manero, Carlos E. Bueso-Ramos, Courtney D. DiNardo, Sharon Bledsoe, Naval G. Daver, Uday Popat, Marina Y. Konopleva, Lingsha Zhou, Sherry Pierce, Zeev E. Estrov, Gautam M. Borthakur, Maro Ohanian, Wei Qiao, Lucia Masarova, Xuemei Wang, Po Yee Mak, Jorge Cortes, Elias Jabbour, Srdan Verstovsek
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3163–3173.
https://doi.org/10.1182/bloodadvances.2020003829
Published: 2021
Journal Articles

A predictive algorithm using clinical and laboratory parameters may assist in ruling out and in diagnosing MDS

Howard S. Oster, Simon Crouch, Alexandra Smith, Ge Yu, Bander Abu Shrkihe, Shoham Baruch, Albert Kolomansky, Jonathan Ben-Ezra, Shachar Naor, Pierre Fenaux, Argiris Symeonidis, Reinhard Stauder, Jaroslav Cermak, Guillermo Sanz, Eva Hellström-Lindberg, Luca Malcovati, Saskia Langemeijer, Ulrich Germing, Mette Skov Holm, Krzysztof Madry, Agnes Guerci-Bresler, Dominic Culligan, Laurence Sanhes, Juliet Mills, Ioannis Kotsianidis, Corine van Marrewijk, David Bowen, Theo de Witte, Moshe Mittelman
Journal: Blood Advances
Blood Adv (2021) 5 (16): 3066–3075.
https://doi.org/10.1182/bloodadvances.2020004055
Published: 2021
Journal Articles

Wild-type HIV infection after treatment with lentiviral gene therapy for β-thalassemia

Suradej Hongeng, Usanarat Anurathapan, Duantida Songdej, Angsana Phuphuakrat, Kesinee Jongrak, Geoffrey Parsons, Briana Deary, Melissa Bonner, Gabor Veres, Mohammed Asmal
Journal: Blood Advances
Blood Adv (2021) 5 (13): 2701–2706.
https://doi.org/10.1182/bloodadvances.2020003680
Published: 2021
Journal Articles

Zanubrutinib for the treatment of relapsed or refractory mantle cell lymphoma

Clinical Trials & Observations
Constantine S. Tam, Stephen Opat, David Simpson, Gavin Cull, Javier Munoz, Tycel J. Phillips, Won Seog Kim, Simon Rule, Siminder Kaur Atwal, Rachel Wei, William Novotny, Jane Huang, Michael Wang, Judith Trotman
Journal: Blood Advances
Blood Adv (2021) 5 (12): 2577–2585.
https://doi.org/10.1182/bloodadvances.2020004074
Published: 2021
Includes: Supplemental data
Journal Articles

Development of luspatercept to treat ineffective erythropoiesis

Clinical Trials & Observations
Anne Sophie Kubasch, Pierre Fenaux, Uwe Platzbecker
Journal: Blood Advances
Blood Adv (2021) 5 (5): 1565–1575.
https://doi.org/10.1182/bloodadvances.2020002177
Published: 2021
Journal Articles

ACVR1/JAK1/JAK2 inhibitor momelotinib reverses transfusion dependency and suppresses hepcidin in myelofibrosis phase 2 trial

Clinical Trials & Observations
Stephen T. Oh, Moshe Talpaz, Aaron T. Gerds, Vikas Gupta, Srdan Verstovsek, Ruben Mesa, Carole B. Miller, Candido E. Rivera, Angela G. Fleischman, Swati Goel, Mark L. Heaney, Casey O’Connell, Murat O. Arcasoy, Yafeng Zhang, Jun Kawashima, Tomas Ganz, Mark Kowalski, Carrie Baker Brachmann
Journal: Blood Advances
Blood Adv (2020) 4 (18): 4282–4291.
https://doi.org/10.1182/bloodadvances.2020002662
Published: 2020
Includes: Supplemental data
Journal Articles

Iron deficiency following bariatric surgery: a retrospective cohort study

Clinical Trials & Observations
Zachary Gowanlock, Anastasiya Lezhanska, Maeve Conroy, Mark Crowther, Maria Tiboni, Lawrence Mbuagbaw, Deborah M. Siegal
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3639–3647.
https://doi.org/10.1182/bloodadvances.2020001880
Published: 2020
Includes: Supplemental data
Journal Articles

Clinical characteristics and treatment outcomes of newly diagnosed multiple myeloma with chromosome 1q abnormalities

Clinical Trials & Observations
Nadine Abdallah, Patricia Greipp, Prashant Kapoor, Morie A. Gertz, Angela Dispenzieri, Linda B. Baughn, Martha Q. Lacy, Suzanne R. Hayman, Francis K. Buadi, David Dingli, Ronald S. Go, Yi L. Hwa, Amie Fonder, Miriam Hobbs, Yi Lin, Nelson Leung, Taxiarchis Kourelis, Rahma Warsame, Mustaqeem Siddiqui, John Lust, Robert A. Kyle, Leif Bergsagel, Rhett Ketterling, S. Vincent Rajkumar, Shaji K. Kumar
Journal: Blood Advances
Blood Adv (2020) 4 (15): 3509–3519.
https://doi.org/10.1182/bloodadvances.2020002218
Published: 2020
Includes: Supplemental data
Journal Articles

Safety and efficacy of the combination of sonidegib and ruxolitinib in myelofibrosis: a phase 1b/2 dose-finding study

Clinical Trials & Observations
Vikas Gupta, Denise Wolleschak, Hans Hasselbalch, Alessandro Maria Vannucchi, Steffen Koschmieder, Francisco Cervantes, Yang Li, Tuochuan Dong, Monika Wroclawska, Savita Bharathy, Claire Harrison
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3063–3071.
https://doi.org/10.1182/bloodadvances.2019001212
Published: 2020
Includes: Supplemental data
Journal Articles

Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias

Clinical Trials & Observations
Xing Fan, Ronan Desmond, Thomas Winkler, David J. Young, Bogdan Dumitriu, Danielle M. Townsley, Fernanda Gutierrez-Rodrigues, Jennifer Lotter, Janet Valdez, Stephanie E. Sellers, Ma Evette Barranta, Ruba N. Shalhoub, Colin O. Wu, Maher Albitar, Katherine R. Calvo, Neal S. Young, Cynthia E. Dunbar
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1700–1710.
https://doi.org/10.1182/bloodadvances.2020001657
Published: 2020
Includes: Supplemental data
Journal Articles

A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease

Clinical Trials & Observations
Mark A. Schroeder, H. Jean Khoury, Madan Jagasia, Haris Ali, Gary J. Schiller, Karl Staser, Jaebok Choi, Leah Gehrs, Michael C. Arbushites, Ying Yan, Peter Langmuir, Nithya Srinivas, Michael Pratta, Miguel-Angel Perales, Yi-Bin Chen, Gabrielle Meyers, John F. DiPersio
Journal: Blood Advances
Blood Adv (2020) 4 (8): 1656–1669.
https://doi.org/10.1182/bloodadvances.2019001043
Published: 2020
Includes: Supplemental data
Journal Articles

Inhibition of complement C1s in patients with cold agglutinin disease: lessons learned from a named patient program

Clinical Trials & Observations
Georg Gelbenegger, Christian Schoergenhofer, Ulla Derhaschnig, Nina Buchtele, Christian Sillaber, Michael Fillitz, Thomas M. Schenk, Shirley D’Sa, Ronwyn Cartwright, James C. Gilbert, Bernd Jilma, Ulrich Jaeger
Journal: Blood Advances
Blood Adv (2020) 4 (6): 997–1005.
https://doi.org/10.1182/bloodadvances.2019001321
Published: 2020
Includes: Supplemental data
Journal Articles

Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche

Siyang Hao, Jie Xiang, Dai-Chen Wu, James W. Fraser, Baiye Ruan, Jingwei Cai, Andrew D. Patterson, Zhi-Chun Lai, Robert F. Paulson
Journal: Blood Advances
Blood Adv (2019) 3 (14): 2205–2217.
https://doi.org/10.1182/bloodadvances.2019000375
Published: 2019
Includes: Supplemental data
Journal Articles

The splicing factor Sf3b1 regulates erythroid maturation and proliferation via TGFβ signaling in zebrafish

Adriana De La Garza, Rosannah C. Cameron, Varun Gupta, Ellen Fraint, Sara Nik, Teresa V. Bowman
Journal: Blood Advances
Blood Adv (2019) 3 (14): 2093–2104.
https://doi.org/10.1182/bloodadvances.2018027714
Published: 2019
Includes: Supplemental data
Journal Articles

Long-term safety of single-agent ibrutinib in patients with chronic lymphocytic leukemia in 3 pivotal studies

Clinical Trials & Observations
Steven E. Coutre, John C. Byrd, Peter Hillmen, Jacqueline C. Barrientos, Paul M. Barr, Stephen Devereux, Tadeusz Robak, Thomas J. Kipps, Anna Schuh, Carol Moreno, Richard R. Furman, Jan A. Burger, Michael O’Dwyer, Paolo Ghia, Rudolph Valentino, Stephen Chang, James P. Dean, Danelle F. James, Susan M. O’Brien
Journal: Blood Advances
Blood Adv (2019) 3 (12): 1799–1807.
https://doi.org/10.1182/bloodadvances.2018028761
Published: 2019
Includes: Supplemental data
Journal Articles

Mutations in the zebrafish hmgcs1 gene reveal a novel function for isoprenoids during red blood cell development

Jose A. Hernandez, Victoria L. Castro, Nayeli Reyes-Nava, Laura P. Montes, Anita M. Quintana
Journal: Blood Advances
Blood Adv (2019) 3 (8): 1244–1254.
https://doi.org/10.1182/bloodadvances.2018024539
Published: 2019
Includes: Supplemental data
Journal Articles

Management of cancer-associated anemia with erythropoiesis-stimulating agents: ASCO/ASH clinical practice guideline update

Julia Bohlius, Kari Bohlke, Roberto Castelli, Benjamin Djulbegovic, Maryam B. Lustberg, Massimo Martino, Giannis Mountzios, Namrata Peswani, Laura Porter, Tiffany N. Tanaka, Gianluca Trifirò, Hushan Yang, Alejandro Lazo-Langner
Journal: Blood Advances
Blood Adv (2019) 3 (8): 1197–1210.
https://doi.org/10.1182/bloodadvances.2018030387
Published: 2019
Includes: Supplemental data