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James S. O'Donnell
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Journal Articles

O-glycan determinants regulate VWF trafficking to Weibel-Palade bodies

Ellie Karampini, Dearbhla Doherty, Petra E. Bürgisser, Massimiliano Garre, Ingmar Schoen, Stephanie Elliott, Ruben Bierings, James S. O’Donnell
Journal: Blood Advances
Blood Adv (2024) 8 (12): 3254–3266.
https://doi.org/10.1182/bloodadvances.2023012499
Published: 2024
Journal Articles

VWF–ADAMTS13 axis dysfunction in children with sickle cell disease treated with hydroxycarbamide vs blood transfusion

Helen Fogarty, Azaz Ahmad, Ferdows Atiq, Dearbhla Doherty, Soracha Ward, Ellie Karampini, Aisling Rehill, Gemma Leon, Ciara Byrne, Rosena Geoghegan, Helena Conroy, Mary Byrne, Ulrich Budde, Sonja Schneppenheim, Ciara Sheehan, Noel Ngwenya, Ross I. Baker, Roger J. S. Preston, Emma Tuohy, Corrina McMahon, James S. O’Donnell
Journal: Blood Advances
Blood Adv (2023) 7 (22): 6974–6989.
https://doi.org/10.1182/bloodadvances.2023010824
Published: 2023
Includes: Supplemental data
Journal Articles

Enhanced VWF clearance in low VWF pathogenesis: limitations of the VWFpp/VWF:Ag ratio and clinical significance

Dearbhla Doherty, Michelle Lavin, Mary Byrne, Margaret Nolan, Jamie M. O’Sullivan, Kevin Ryan, Niamh M. O’Connell, Sandra L. Haberichter, Pamela A. Christopherson, Jorge Di Paola, Paula D. James, James S. O’Donnell
Journal: Blood Advances
Blood Adv (2023) 7 (3): 302–308.
https://doi.org/10.1182/bloodadvances.2022007340
Published: 2023
Includes: Supplemental data
Journal Articles

Laboratory assays of VWF activity and use of desmopressin trials in the diagnosis of VWD: a systematic review and meta-analysis

Clinical Trials & Observations
Mohamad A. Kalot, Nedaa Husainat, Omar Abughanimeh, Osama Diab, Abdallah El Alayli, Sammy Tayiem, Bader Madoukh, Ahmad Dimassi, Aref Qureini, Barbara Ameer, Jeroen Eikenboom, Nicolas Giraud, Sandra Haberichter, Vicky Jacobs-Pratt, Barbara A. Konkle, Simon McRae, Robert Montgomery, James S. O’Donnell, Romina Brignardello-Petersen, Veronica Flood, Nathan T. Connell, Paula James, Reem A. Mustafa
Journal: Blood Advances
Blood Adv (2022) 6 (12): 3735–3745.
https://doi.org/10.1182/bloodadvances.2021005431
Published: 2022
Includes: Supplemental data
Journal Articles

von Willebrand factor levels in the diagnosis of von Willebrand disease: a systematic review and meta-analysis

Clinical Trials & Observations
Mohamad A. Kalot, Nedaa Husainat, Abdallah El Alayli, Omar Abughanimeh, Osama Diab, Sammy Tayiem, Bader Madoukh, Ahmad B. Dimassi, Aref Qureini, Barbara Ameer, Jeroen C.J. Eikenboom, Nicolas Giraud, Claire McLintock, Simon McRae, Robert R. Montgomery, James S. O’Donnell, Nikole Scappe, Robert F. Sidonio, Jr, Romina Brignardello-Petersen, Veronica H. Flood, Nathan T. Connell, Paula D. James, Reem A. Mustafa
Journal: Blood Advances
Blood Adv (2021) 6 (1): 62–71.
https://doi.org/10.1182/bloodadvances.2021005430
Published: 2021
Includes: Supplemental data
Journal Articles

Bleeding assessment tools in the diagnosis of VWD in adults and children: a systematic review and meta-analysis of test accuracy

Mohamad A. Kalot, Nedaa Husainat, Sammy Tayiem, Abdallah El Alayli, Ahmad B. Dimassi, Osama Diab, Omar Abughanimeh, Bader Madoukh, Aref Qureini, Barbara Ameer, Jorge Di Paola, Jeroen C.J. Eikenboom, Vicky Jacobs-Pratt, Claire McLintock, Robert Montgomery, James S. O’Donnell, Robert Sidonio, Jr., Romina Brignardello-Petersen, Veronica Flood, Nathan T. Connell, Paula D. James, Reem A. Mustafa
Journal: Blood Advances
Blood Adv (2021) 5 (23): 5023–5031.
https://doi.org/10.1182/bloodadvances.2021004368
Published: 2021
Includes: Supplemental data
Journal Articles

von Willebrand disease: proposing definitions for future research

Clinical Trials & Observations
Nathan T. Connell, Paula D. James, Romina Brignardello-Petersen, Rezan Abdul-Kadir, Barbara Ameer, Alice Arapshian, Susie Couper, Jorge Di Paola, Jeroen Eikenboom, Nicolas Giraud, Jean M. Grow, Sandra Haberichter, Vicki Jacobs-Pratt, Barbara A. Konkle, Peter Kouides, Michael Laffan, Michelle Lavin, Frank W. G. Leebeek, Claire McLintock, Simon McRae, Robert Montgomery, Sarah H. O'Brien, James S. O'Donnell, Margareth C. Ozelo, Nikole Scappe, Robert Sidonio, Jr, Alberto Tosetto, Angela C. Weyand, Mohamad A. Kalot, Nedaa Husainat, Reem A. Mustafa, Veronica H. Flood
Journal: Blood Advances
Blood Adv (2021) 5 (2): 565–569.
https://doi.org/10.1182/bloodadvances.2020003620
Published: 2021
Journal Articles

ASH ISTH NHF WFH 2021 guidelines on the diagnosis of von Willebrand disease

Paula D. James, Nathan T. Connell, Barbara Ameer, Jorge Di Paola, Jeroen Eikenboom, Nicolas Giraud, Sandra Haberichter, Vicki Jacobs-Pratt, Barbara Konkle, Claire McLintock, Simon McRae, Robert R. Montgomery, James S. O’Donnell, Nikole Scappe, Robert Sidonio, Jr, Veronica H. Flood, Nedaa Husainat, Mohamad A. Kalot, Reem A. Mustafa
Journal: Blood Advances
Blood Adv (2021) 5 (1): 280–300.
https://doi.org/10.1182/bloodadvances.2020003265
Published: 2021
Includes: Supplemental data
Journal Articles

Low VWF: insights into pathogenesis, diagnosis, and clinical management

James S. O’Donnell
Journal: Blood Advances
Blood Adv (2020) 4 (13): 3191–3199.
https://doi.org/10.1182/bloodadvances.2020002038
Published: 2020
Journal Articles

Parasite histones are toxic to brain endothelium and link blood barrier breakdown and thrombosis in cerebral malaria

Christopher A. Moxon, Yasir Alhamdi, Janet Storm, Julien M. H. Toh, Dagmara McGuinness, Joo Yeon Ko, George Murphy, Steven Lane, Terrie E. Taylor, Karl B. Seydel, Sam Kampondeni, Michael Potchen, James S. O’Donnell, Niamh O’Regan, Guozheng Wang, Guillermo García-Cardeña, Malcolm Molyneux, Alister G. Craig, Simon T. Abrams, Cheng-Hock Toh
Journal: Blood Advances
Blood Adv (2020) 4 (13): 2851–2864.
https://doi.org/10.1182/bloodadvances.2019001258
Published: 2020
Includes: Supplemental data
Journal Articles

Apolipoprotein A-I enhances activated protein C cytoprotective activity

Eimear M. Gleeson, Aisling M. Rehill, Orla Willis Fox, Fionnuala Ni Ainle, Cormac J. McDonnell, Hannah J. Rushe, Seán McCluskey, James S. O’Donnell, Roger J. S. Preston
Journal: Blood Advances
Blood Adv (2020) 4 (11): 2404–2408.
https://doi.org/10.1182/bloodadvances.2019001316
Published: 2020
Includes: Supplemental data
Journal Articles

Significant gynecological bleeding in women with low von Willebrand factor levels

Clinical Trials & Observations
Michelle Lavin, Sonia Aguila, Niall Dalton, Margaret Nolan, Mary Byrne, Kevin Ryan, Barry White, Niamh M. O’Connell, Jamie M. O’Sullivan, Jorge Di Paola, Paula D. James, James S. O’Donnell
Journal: Blood Advances
Blood Adv (2018) 2 (14): 1784–1791.
https://doi.org/10.1182/bloodadvances.2018017418
Published: 2018
Includes: Supplemental data