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Issue Archive

Volume 9, Issue 12
June 24 2025
Blood Advances Cover Image for Volume 9, Issue 12

Table of Contents

INSIDE BLOOD ADVANCES

Extracellular vesicles for CAR T-cell therapy immunomonitoring
Marion Klea Pinheiro,Benoît Vingert
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Long-term data needed for SCD gene therapy
Alexis Leonard
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REVIEW ARTICLES

Venous thrombosis unchained: Pandora’s box of noninflammatory mechanisms
Sophie R. M. Smith,Neil V. Morgan,Alexander Brill
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Current developments in T-cell receptor therapy for acute myeloid leukemia
Sayali Gore,Emily Blyth,Marie Bleakley,Koon Lee,Kenneth Micklethwaite,Kavitha Gowrishankar
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A road map for uniform, comprehensive long-term follow-up after curative therapy for sickle cell disease
Shalini Shenoy,Julie Kanter,Adetola Kassim,Courtney Fitzhugh,Elizabeth Stenger,Monica Bhatia,Lydia Pecker,Lakshmanan Krishnamurti,Allison A. King
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Supplemental data
Long-term data needed for SCD gene therapy
Alexis Leonard
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CLINICAL TRIALS AND OBSERVATIONS

Prognostic role of interim PET in follicular lymphoma: a post hoc study of FOLL12 trial by Fondazione Italiana Linfomi
Clinical Trials & Observations
Rexhep Durmo,Stephane Chauvie,Federico Fallanca,Fabrizio Bergesio,Antonio Pinto,Ilaria Del Giudice,Marta Coscia,Paolo Corradini,Emanuele Angelucci,Patrizia Tosi,Roberto Freilone,Filippo Ballerini,Alessia Bari,Domenico Pastore,Pier Luigi Zinzani,Silvia Bolis,Leonardo Flenghi,Arcangelo Liso,Jacopo Olivieri,Luigi Marcheselli,Michele Merli,Annibale Versari,Luca Guerra,Stefano Luminari
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Supplemental data
Gene therapy for hemophilia B: results from the phase 1/2 101HEMB01/02 studies
Clinical Trials & Observations
Steven Pipe,Allen Poma,Anita Rajasekhar,Tamara Everington,Serap Sankoh,Jack Allen,Jason Cataldo,Eric Crombez
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Neurocognitive gains among Ugandan children with sickle cell anemia on hydroxyurea: 18-month interim trial results
Clinical Trials & Observations Global Advances
Shubaya K. Naggayi,Dennis Kalibbala,Vincent Mboizi,John Ssenkusu,Zhezhen Jin,Caterina Rosano,Deogratias Munube,Bill Wambaka,Ruth Namazzi,Phillip Kasirye,Maxencia Kabatabaazi,Grace Nambatya,Susan Murungi,Catherine Nabaggala,Maria Nakafeero,Ian R. Troidl,Robert Opoka,Richard Idro,Paul Bangirana,Nancy S. Green
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HEALTH SERVICES AND OUTCOMES

Changes in acute care use among people with sickle cell disease after adoption of a prescription drug monitoring program
Blake T. McGee,Brandon K. Attell,James Marton,Adrienne Harris,Brett Alfrey,Lindsey L. Cohen,Angela B. Snyder
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IMMUNOBIOLOGY AND IMMUNOTHERAPY

CD19.CAR T-cell–derived extracellular vesicles express CAR and kill leukemic cells, contributing to antineoplastic therapy
Paola Lanuti,Francesco Guardalupi,Giulia Corradi,Rosalba Florio,Davide Brocco,Serena Veschi,Elsa Pennese,Domenico De Bellis,Francesca D’Ascanio,Anna Piro,Laura De Lellis,Pasquale Simeone,Maria Concetta Cufaro,Serena Pilato,Isabella D’Amario,Ida Villanova,Barbara Di Francesco,Lucia Di Re,Fabio Verginelli,Damiana Pieragostino,Prassede Salutari,Fabrizia Colasante,Annalisa Natale,Maria Vittoria Mattoli,Simone Vespa,Antonella Fontana,Raffaella Giancola,Bianca Fabi,Stefano Baldoni,Stella Santarone,Francesco Restuccia,Nicola Tinari,Piero Del Boccio,Alessandro Cama,Mauro Di Ianni
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Supplemental data
Extracellular vesicles for CAR T-cell therapy immunomonitoring
Marion Klea Pinheiro,Benoît Vingert
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LYMPHOID NEOPLASIA

Comparative efficacy of Bruton tyrosine kinase inhibitors in high-risk relapsed/refractory CLL: a network meta-analysis
Mazyar Shadman,Jennifer R. Brown,Leyla Mohseninejad,Keri Yang,Heather Burnett,Binod Neupane,Rhys Williams,Nicole Lamanna,Susan M. O'Brien,Alessandra Tedeschi,Constantine S. Tam
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Spatial transcriptomics of progression gene signature and tumor microenvironment leading to progression in mycosis fungoides
Myoung Eun Choi,Gyeonghoon Kim,Hwa-Jeong Shin,Chong Hyun Won,Sung Eun Chang,Mi Woo Lee,Woo Jin Lee
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The role of miR-150-5p/E2F3/survivin axis in the pathogenesis of plasmablastic lymphoma and its therapeutic potential
Miriam Verdú-Bou,Maria Joao Baptista,Marcelo Lima Ribeiro,Aleix Méndez-López,Núria Profitós-Pelejà,Fabian Frontzek,Gaël Roué,José Luís Mate,Mireia Pellicer,Pau Abrisqueta,Josep Castellví,Mariana Bastos-Oreiro,Javier Menárguez,Miguel Alcoceba,Eva González-Barca,Fina Climent,Antonio Salar,Juan-Manuel Sancho,Annette M. Staiger,German Ott,Ioannis Anagnostopoulos,Manel Esteller,Georg Lenz,Gustavo Tapia,José-Tomás Navarro
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Supplemental data
Binding of RHOA G17V to p300 enhances its HAT activity: a new mechanism of epigenetic deregulation in TFH lymphoma
David Vallois,Mélanie Juilland,Kalliopi Ioannidou,François Lemonnier,Edoardo Missiaglia,Bettina Bisig,Margot Thome,Laurence de Leval
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MYELOID NEOPLASIA

Distinct routes of clonal progression in SF3B1-mutant myelodysplastic syndromes
Martina Sarchi,Courtnee A. Clough,Anna Gallì,Cristina Picone,Beatrice Ferrari,Edie I. Crosse,Laura D. Baquero Galvis,Claudia Fiducioso,Nelli Aydinyan,J. Philip Creamer,Sara Pozzi,Elisabetta Molteni,Chiara Elena,Robert K. Bradley,Luca Malcovati,Sergei Doulatov
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RED CELLS, IRON, AND ERYTHROPOIESIS

Triaging acute chest syndrome clinical decision-making using bedside SaO2/FiO2 ratio
Austin Wesevich,Megan Woelkers,Ayodeji Adegunsoye,Adam J. Wesevich,Mark J. Ratain,Gabrielle Lapping-Carr
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Neuroprotective, anti-inflammatory, and analgesic activity of palmitoylethanolamide in sickle cell mice
Donovan A. Argueta,Bryant Avalos,Yugal Goel,Huy Tran,Yannick Fotio,Daniele Piomelli,Nicholas V. DiPatrizio,Kalpna Gupta
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THROMBOSIS AND HEMOSTASIS

Cooperative effect between anti-PF4/H and anti-PF4 antibodies increases cell activation and thrombotic risk in HIT
Sandra Billy,Caroline Vayne,Ophélie Bertin,Elodie Miquelestorena-Standley,Noémie Charuel,Annabelle Dupont,Loïs Coënon,Claire Pouplard,Yotis A. Senis,Yves Gruel,Jérôme Rollin
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TRANSFUSION MEDICINE

Red blood cells with reduced deformability are selectively cleared from circulation in a mouse model
Emel Islamzada,Kerryn Matthews,Erik S. Lamoureux,Simon P. Duffy,Mark D. Scott,Hongshen Ma
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TRANSPLANTATION

AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling
Alexander Zähringer,Inês Morgado,Daniel Erny,Florian Ingelfinger,Jana Gawron,Sangya Chatterjee,Valentin Wenger,Dominik Schmidt,Lennard Schwöbel,Rachael C. Adams,Marlene Langenbach,Alina Hartmann,Natascha Osswald,Julian Wolf,Günther Schlunck,Priscilla S. Briquez,Kathleen Grueter,Dietrich A. Ruess,Ian Frew,Ann-Cathrin Burk,Verena Holzmüller,Bodo Grimbacher,David Michonneau,Geoffroy Andrieux,Gérard Socié,Julia Kolter,Melanie Boerries,Marie Follo,Franziska Blaeschke,Lisa Sevenich,Marco Prinz,Robert Zeiser,Janaki Manoja Vinnakota
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VASCULAR BIOLOGY

Endothelial cell activation enhances thromboinflammation in vaccine-induced immune thrombotic thrombocytopenia
Alexander Dupuy,Xiaoming Liu,Yvonne Kong,Miao Qi,Jose Perdomo,Jemma Fenwick,Jessica Tieng,Bede Johnston,Qiyu Sara Shi,Mark Larance,Yingqi Zhang,Lining Arnold Ju,Paul Coleman,Jennifer Gamble,Elizabeth E. Gardiner,Mortimer Poncz,Huyen Tran,Vivien Chen,Freda H. Passam
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RESEARCH LETTERS

Nitrated fatty acids protect against acute kidney injury in sickle cell disease
Mara Carreño,Diane Lenhart,Rajat Pant,Paritosh Mondal,Sonia R. Salvatore,Maria F. Pires,Enrico M. Novelli,Francisco J. Schopfer,Samit Ghosh,Dario A. Vitturi
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Hematopoietic progenitor kinase-1 inhibition improves the in vitro efficacy of bispecific antibodies in CLL
Yamit Shorer Arbel,Liron Yitzhak,Ben-Zion Katz,Yair Herishanu
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Supplemental data
The impact of CMV reactivation on mortality after chimeric antigen receptor T-cell therapy
Clinical Trials & Observations
Eleftheria Kampouri,Patrick Flaherty,Hu Xie,Mandeep K. Sekhon,Clementine Chalal,Terry L. Stevens-Ayers,Damian J. Green,Jordan Gauthier,Mazyar Shadman,Ailyn C. Pérez-Osorio,Keith R. Jerome,Wendy M. Leisenring,Michael J. Boeckh,Joshua A. Hill
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Impact of clonal hematopoiesis on clinical outcomes to BCMA CAR-T in multiple myeloma
Clinical Trials & Observations
Joshua N. Gustine,Andrew R. Branagan,Diana D. Cirstea,Farah Rexha,Ryan Han,Andrew J. Yee,Marcela V. Maus,Matthew J. Frigault,Noopur S. Raje
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COMMENTARY

Estimating rare genetic disease prevalence: a challenging task
Koichi Kokame
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RESPONSE

Clarifying the role of p.Gln723Lys in hTTP prevalence
Omid Seidizadeh,Andrea Cairo,Ilaria Mancini,James N. George,Flora Peyvandi
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  • Cover Image

    Cover Image

    issue cover

    Immunostaining of human umbilical vein endothelial cells for spike protein (red) after incubation with ChAdOx1 nCOV-19 adenoviral vaccine for 16 hours. Nuclei were stained in blue. See the article by Dupuy et al.

All Issues

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