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Volume 7, Issue 9

May 9 2023

In this Issue

INSIDE BLOOD ADVANCES
CLINICAL TRIALS AND OBSERVATIONS
HEALTH SERVICES AND OUTCOMES
IMMUNOBIOLOGY AND IMMUNOTHERAPY
LYMPHOID NEOPLASIA
MYELOID NEOPLASIA
PLATELETS AND THROMBOPOIESIS
RED CELLS, IRON, AND ERYTHROPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
RESEARCH LETTERS
ERRATUM

INSIDE BLOOD ADVANCES

Cord blood power and the definition of success after BMT
Clinical Trials & Observations

Jaap Jan Boelens,Andromachi Scaradavou

View Articletitled, Cord blood power and the definition of success after BMT

Curing CLL: one clone at a time
Clinical Trials & Observations

Burcu Aslan,Shady I. Tantawy,Varsha Gandhi

View Articletitled, Curing CLL: one clone at a time

CLINICAL TRIALS AND OBSERVATIONS

Cord blood transplantation for nonmalignant disorders: early functional immunity and high survival
Clinical Trials & Observations

Caridad Martinez,Paibel Aguayo-Hiraldo,Natalia Chaimowitz,Lisa Forbes,Nicholas Rider,Sarah Nicholas,Filiz Seeborg,Javier Chinen,Ivan Chinn,Carla Davis,Howard Roseblatt,Lenora Noroski,Bilal Omer,Tami John,Khaled Yassine,Swati Naik,John Craddock,Saleh Bhar,Carl Allen,Nabil Ahmed,Ghadir Sasa,David Steffin,Erin Doherty,Anil George,Baheyeldin Salem,Brian Friend,Meenakshi Hegde,Malcolm K. Brenner,Helen E. Heslop,Ann Leen,Amanda Peña,Mengfen Wu,I. Celine Hanson,Robert A. Krance

View Articletitled, Cord blood transplantation for nonmalignant disorders: early functional immunity and high survival

Cord blood power and the definition of success after BMT
Clinical Trials & Observations

Jaap Jan Boelens,Andromachi Scaradavou

View Articletitled, Cord blood power and the definition of success after BMT

Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML
Clinical Trials & Observations

Stéphane de Botton,Thomas Cluzeau,Carlos Vigil,Rachel J. Cook,Philippe Rousselot,David A. Rizzieri,Jane L. Liesveld,Pierre Fenaux,Thorsten Braun,Anne Banos,Joseph G. Jurcic,Mikkael A. Sekeres,Michael R. Savona,Gail J. Roboz,Dale Bixby,Kate Madigan,Angela Volkert,Kristin Stephens,Qing Kang-Fortner,Kristen Baker,Sofia Paul,Michael McKeown,John Carulli,Matthew Eaton,Graeme Hodgson,Christopher Fiore,Michael J. Kelly,David A. Roth,Eytan M. Stein

View Articletitled, Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML

Supplemental data

Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones
Clinical Trials & Observations

Afaf E. G. Osman,Nuria Mencia-Trinchant,Caner Saygin,Luke Moma,Aelin Kim,Genevieve Housman,Matthew Pozsgai,Eti Sinha,Pooja Chandra,Duane C. Hassane,Andrea Sboner,Kishan Sangani,Nick DiNardi,Christopher Johnson,Sara S. Wallace,Bana Jabri,Hue Luu,Monica L. Guzman,Pinkal Desai,Lucy A. Godley

View Articletitled, Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones

Supplemental data

HEALTH SERVICES AND OUTCOMES

Health following recovery from immune thrombotic thrombocytopenic purpura: the patient’s perspective

Rachel A. Kelley,Marshall K. Cheney,Clare M. Martin,Spero Cataland,Lauren B. Quick,San Keller,Sara K. Vesely,Amanda J. Llaneza,Mohamad O. Khawandanah,Janna M. Journeycake,Julie A. Panepinto,Deirdra R. Terrell

View Articletitled, Health following recovery from immune thrombotic thrombocytopenic purpura: the patient’s perspective

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Shared graft-versus-leukemia minor histocompatibility antigens in DISCOVeRY-BMT

Kelly S. Olsen,Othmane Jadi,Sarah Dexheimer,Dante S. Bortone,Steven P. Vensko, II,Sarah Bennett,Hancong Tang,Marisa Diiorio,Tanvi Saran,David Dingfelder,Qianqian Zhu,Yiwen Wang,Christopher A. Haiman,Loreall Pooler,Xin Sheng,Amy Webb,Marcelo C. Pasquini,Philip L. McCarthy,Stephen R. Spellman,Eric Weimer,Theresa Hahn,Lara Sucheston-Campbell,Paul M. Armistead,Benjamin G. Vincent

View Articletitled, Shared graft-versus-leukemia minor histocompatibility antigens in DISCOVeRY-BMT

Supplemental data

Characteristics of circulating KSHV-infected viroblasts during active KSHV⁺ multicentric Castleman disease

Gregoire Martin de Frémont,Anthony Vanjak,Zineb Sbihi,Silene Knapp,Margaux Garzaro,Marwa Chbihi,Benjamin Fournier,Justine Poirot,Antoine Dossier,Marc-Antoine Silvestrini,Juliette Villemonteix,Véronique Meignin,Lionel Galicier,Rémi Bertinchamp,Jerome Le Goff,Maud Salmona,Edouard Flamarion,Charles Cassius,Celeste Lebbé,Anne Marie Ronchetti,Sylvain Latour,Eric Oksenhendler,Guislaine Carcelain,David Boutboul

View Articletitled, Characteristics of circulating KSHV-infected viroblasts during active KSHV+ multicentric Castleman disease

Supplemental data

Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells

Ilaria M. Michelozzi,Eduardo Gomez-Castaneda,Ruben V. C. Pohle,Ferran Cardoso Rodriguez,Jahangir Sufi,Pau Puigdevall Costa,Meera Subramaniyam,Efstratios Kirtsios,Ayad Eddaoudi,Si Wei Wu,Aleks Guvenel,Jonathan Fisher,Sara Ghorashian,Martin A. Pule,Christopher J. Tape,Sergi Castellano,Persis J. Amrolia,Alice Giustacchini

View Articletitled, Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells

Supplemental data

Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment

Silvia Panetti,Nicola McJannett,Livingstone Fultang,Sarah Booth,Luciana Gneo,Ugo Scarpa,Charles Smith,Ashley Vardon,Lisa Vettore,Celina Whalley,Yi Pan,Csilla Várnai,Hitoshi Endou,Jonathan Barlow,Daniel Tennant,Andrew Beggs,Francis Mussai,Carmela De Santo

View Articletitled, Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment

Supplemental data

TCRvβ-CART therapy mediates high-precision targeting of malignant T-cell clones

Lauren C. Shaw,Mathilde Poussin,Alba Rodriguez-Garcia,Joshua Eggold,Nicholas G. Minutolo,Jie Wang,Alain H. Rook,Stephen J. Schuster,Daniel J. Powell, Jr

View Articletitled, TCRvβ-CART therapy mediates high-precision targeting of malignant T-cell clones

Supplemental data

LYMPHOID NEOPLASIA

AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity

Timon A. Bloedjes,Guus de Wilde,Gerarda H. Khan,Timothy C. Ashby,John D. Shaughnessy, Jr.,Fenghuang Zhan,Riekelt H. Houtkooper,Richard J. Bende,Carel J. M. van Noesel,Marcel Spaargaren,Jeroen E. J. Guikema

View Articletitled, AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity

Supplemental data

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

Aishath Naeem,Filippo Utro,Qing Wang,Justin Cha,Mauno Vihinen,Stephen Martindale,Yinglu Zhou,Yue Ren,Svitlana Tyekucheva,Annette S. Kim,Stacey M. Fernandes,Gordon Saksena,Kahn Rhrissorrakrai,Chaya Levovitz,Brian P. Danysh,Kara Slowik,Raquel A. Jacobs,Matthew S. Davids,James A. Lederer,Rula Zain,C. I. Edvard Smith,Ignaty Leshchiner,Laxmi Parida,Gad Getz,Jennifer R. Brown

View Articletitled, Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

Supplemental data

Curing CLL: one clone at a time
Clinical Trials & Observations

Burcu Aslan,Shady I. Tantawy,Varsha Gandhi

View Articletitled, Curing CLL: one clone at a time

MYELOID NEOPLASIA

CNL and aCML should be considered as a single entity based on molecular profiles and outcomes
Clinical Trials & Observations

Gonzalo Carreño-Tarragona,Alberto Álvarez-Larrán,Claire Harrison,José Carlos Martínez-Ávila,Juan Carlos Hernández-Boluda,Francisca Ferrer-Marín,Deepti H. Radia,Elvira Mora,Sebastian Francis,Teresa González-Martínez,Kathryn Goddard,Manuel Pérez-Encinas,Srinivasan Narayanan,José María Raya,Vikram Singh,Xabier Gutiérrez,Peter Toth,Paula Amat-Martínez,Louisa Mcilwaine,Magda Alobaidi,Karan Mayani,Andrew McGregor,Ruth Stuckey,Bethan Psaila,Adrián Segura,Caroline Alvares,Kerri Davidson,Santiago Osorio,Robert Cutting,Caroline P. Sweeney,Laura Rufián,Laura Moreno,Isabel Cuenca,Jeffery Smith,María Luz Morales,Rodrigo Gil-Manso,Ioannis Koutsavlis,Lihui Wang,Adam J. Mead,María Rozman,Joaquín Martínez-López,Rosa Ayala,Nicholas C. P. Cross

View Articletitled, CNL and aCML should be considered as a single entity based on molecular profiles and outcomes

Supplemental data

Mast cell leukemia: clinical and molecular features and survival outcomes of patients in the ECNM Registry

Vanessa E. Kennedy,Cecelia Perkins,Andreas Reiter,Mohamad Jawhar,Johannes Lübke,Hanneke C. Kluin-Nelemans,William Shomali,Cheryl Langford,Justin Abuel,Olivier Hermine,Marek Niedoszytko,Aleksandra Gorska,Andrzej Mital,Patrizia Bonadonna,Roberta Zanotti,Ilaria Tanasi,Mattias Mattsson,Hans Hagglund,Massimo Triggiani,Akif Selim Yavuz,Jens Panse,Deborah Christen,Marc Heizmann,Khalid Shoumariyeh,Sabine Müller,Chiara Elena,Luca Malcovati,Nicolas Fiorelli,Friederike Wortmann,Vladan Vucinic,Knut Brockow,Christos Fokoloros,Sotirios G. Papageorgiou,Christine Breynaert,Dominique Bullens,Michael Doubek,Anja Ilerhaus,Irena Angelova-Fischer,Oleksii Solomianyi,Judit Várkonyi,Vito Sabato,Axel Rüfer,Tanja Daniela Schug,Maud A. W. Hermans,Anna Belloni Fortina,Francesca Caroppo,Horia Bumbea,Theo Gulen,Karin Hartmann,Hanneke Oude Elberink,Juliana Schwaab,Michel Arock,Peter Valent,Wolfgang R. Sperr,Jason Gotlib

View Articletitled, Mast cell leukemia: clinical and molecular features and survival outcomes of patients in the ECNM Registry

Supplemental data

Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML

Nam H. K. Nguyen,Roya Rafiee,Abderrahmane Tagmount,Amin Sobh,Alex Loguinov,Angelica K. de Jesus Sosa,Abdelrahman H. Elsayed,Mohammed Gbadamosi,Nathan Seligson,Christopher R. Cogle,Jeffery Rubnitz,Raul Ribeiro,James Downing,Xueyuan Cao,Stanley B. Pounds,Christopher D. Vulpe,Jatinder K. Lamba

View Articletitled, Genome-wide CRISPR/Cas9 screen identifies etoposide response modulators associated with clinical outcomes in pediatric AML

Supplemental data

Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms
Clinical Trials & Observations

Jack Chovanec,Ilker Tunc,Jason Hughes,Joseph Halstead,Allyson Mateja,Yihui Liu,Michael P. O’Connell,Jiwon Kim,Young Hwan Park,Qinlu Wang,Quang Le,Mehdi Pirooznia,Neil N. Trivedi,Yun Bai,Yuzhi Yin,Amy P. Hsu,Joshua McElwee,Sheryce Lassiter,Celeste Nelson,Judy Bandoh,Thomas DiMaggio,Julij Šelb,Matija Rijavec,Melody C. Carter,Hirsh D. Komarow,Vito Sabato,Joshua Steinberg,Kurt M. Hafer,Elizabeth Feuille,Christopher S. Hourigan,Justin Lack,Paneez Khoury,Irina Maric,Roberta Zanotti,Patrizia Bonadonna,Lawrence B. Schwartz,Joshua D. Milner,Sarah C. Glover,Didier G. Ebo,Peter Korošec,George H. Caughey,Erica H. Brittain,Ben Busby,Dean D. Metcalfe,Jonathan J. Lyons

View Articletitled, Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms

Supplemental data

Adaptation of Serious Illness Care Program to be delivered via telehealth for older patients with hematologic malignancy
Clinical Trials & Observations

Marissa LoCastro,Chandrika Sanapala,Jason H. Mendler,Sally Norton,Rachelle Bernacki,Thomas Carroll,Heidi D. Klepin,Erin Watson,Jane Liesveld,Eric Huselton,Kristen O’Dwyer,Andrea Baran,Marie Flannery,Benzi Kluger,Kah Poh Loh

View Articletitled, Adaptation of Serious Illness Care Program to be delivered via telehealth for older patients with hematologic malignancy

Supplemental data

Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia

Curtis A. Lachowiez,Nicola Long,Jennifer Saultz,Arpita Gandhi,Laura F. Newell,Brandon Hayes-Lattin,Richard T. Maziarz,Jessica Leonard,Daniel Bottomly,Shannon McWeeney,Jennifer Dunlap,Richard Press,Gabrielle Meyers,Ronan Swords,Rachel J. Cook,Jeffrey W. Tyner,Brian J. Druker,Elie Traer

View Articletitled, Comparison and validation of the 2022 European LeukemiaNet guidelines in acute myeloid leukemia

Supplemental data

PLATELETS AND THROMBOPOIESIS

Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model

Angelina J. Lay,Alexander Dupuy,Lejla Hagimola,Jessica Tieng,Mark Larance,Yunwei Zhang,Jean Yang,Yvonne Kong,Joyce Chiu,Emilia Gray,Zihao Qin,Diana Schmidt,Jessica Maclean,Benjamin Hofma,Marc Ellis,Maggie Kalev-Zylinska,Yair Argon,Shaun P. Jackson,Philip Hogg,Freda H. Passam

View Articletitled, Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model

Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Kindlin-3 deficiency leads to impaired erythropoiesis and erythrocyte cytoskeleton

Dorota Szpak,Chloe Turpin,Utku Goreke,Katarzyna Bialkowska,Kamila M. Bledzka,Dmitriy Verbovetskiy,Narla Mohandas,Umut A. Gurkan,Jun Qin,Edward F. Plow,Elzbieta Pluskota

View Articletitled, Kindlin-3 deficiency leads to impaired erythropoiesis and erythrocyte cytoskeleton

Supplemental data

THROMBOSIS AND HEMOSTASIS

Venous thromboembolism prophylaxis in sickle cell disease: a multicenter cohort study of adolescent inpatients

Jennifer Davila,Joseph Stanek,Sarah H. O'Brien

View Articletitled, Venous thromboembolism prophylaxis in sickle cell disease: a multicenter cohort study of adolescent inpatients

Supplemental data

Prospective Hemophilia Inhibitor PUP Study reveals distinct antibody signatures during FVIII inhibitor eradication

Helmut Paul,Verena Berg,Bagirath Gangadharan,Joel Bowen,Petra LeBeau,Jan Blatný,Christoph Male,Vlad C. Radulescu,Rosa Diaz,Maria Elisa Mancuso,Deborah L. Brown,Birgit M. Reipert

View Articletitled, Prospective Hemophilia Inhibitor PUP Study reveals distinct antibody signatures during FVIII inhibitor eradication

Supplemental data

A novel mouse whole blood thrombin generation assay sensitive to FXI- and FIX-mediated amplification of coagulation

Jun Wan,Pansakorn Tanratana,Mark Roest,Andras Gruber,Rafal Pawlinski,Alisa S. Wolberg,Nigel Mackman,Steven P. Grover

View Articletitled, A novel mouse whole blood thrombin generation assay sensitive to FXI- and FIX-mediated amplification of coagulation

Supplemental data

TRANSPLANTATION

Levofloxacin prophylaxis vs no prophylaxis in patients with neutropenia within an endemic country for carbapenem-resistant GNB

Daniela Clerici,Laura Galli,Raffaella Greco,Anna P. Lugli,Federico Erbella,Marco Ripa,Chiara Tassan Din,Rosamaria Nitti,Fabio Giglio,Sara Mastaglio,Francesca Lorentino,Elisabetta Xue,Francesca Farina,Carmine Liberatore,Andrea Poli,Silvia Carletti,Maria T. Lupo Stanghellini,Matteo G. Carrabba,Andrea A. Assanelli,Annalisa Ruggeri,Massimo Bernardi,Consuelo Corti,Jacopo Peccatori,Nicasio Mancini,Paolo Scarpellini,Fabio Ciceri,Antonella Castagna,Chiara Oltolini

View Articletitled, Levofloxacin prophylaxis vs no prophylaxis in patients with neutropenia within an endemic country for carbapenem-resistant GNB

Supplemental data

Sickle cell disease is a risk factor for transplant-associated thrombotic microangiopathy in children

Michelle Schoettler,Elizabeth Stenger,Kathleen Spencer,Deborah Lutterman,Savanah Rumbika,Jayre Jones,Ann Haight,Suhag Parikh,Muna Qayed,Benjamin Watkins,Lakshmanan Krishnamurti,Kirsten M. Williams,Satheesh Chonat

View Articletitled, Sickle cell disease is a risk factor for transplant-associated thrombotic microangiopathy in children

Supplemental data

RESEARCH LETTERS

Preclinical studies targeting CD74 with STRO-001 antibody-drug conjugate in acute leukemia

Quy Le,Thao Tang,Amanda Leonti,Sommer Castro,Cyd Nourigat McKay,LaKeisha Perkins,Laura Pardo,Danielle Kirkey,Tiffany Hylkema,Lindsey Call,Makia Manselle,Cristina Abrahams,Kristin Bedard,Arturo Molina,Lisa Eidenshinck Brodersen,Michael R. Loken,Katherine Tarlock,Soheil Meshinchi,Keith R. Loeb

View Articletitled, Preclinical studies targeting CD74 with STRO-001 antibody-drug conjugate in acute leukemia

Supplemental data

Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

Justin S. Trory,Attila Munkacsi,Kamila M. Śledź,Jordan Vautrinot,Lucy J. Goudswaard,Molly L. Jackson,Kate J. Heesom,Samantha F. Moore,Alastair W. Poole,Behnam Nabet,Varinder K. Aggarwal,Ingeborg Hers

View Articletitled, Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

Supplemental data

Humoral and cellular responses to SARS-CoV-2 vaccines before and after chimeric antigen receptor–modified T-cell therapy
Clinical Trials & Observations

Michael A. Gonzalez,Atif M. Bhatti,Kristin Fitzpatrick,Jim Boonyaratanakornkit,Meei-Li Huang,Victoria L. Campbell,Jessica Hecht,Sarah Ibrahimi,Shera N. Wanner,Damian J. Green,David G. Maloney,Jordan Gauthier,Andrew J. Cowan,Alexander L. Greninger,Elizabeth M. Krantz,David M. Koelle,Joshua A. Hill

View Articletitled, Humoral and cellular responses to SARS-CoV-2 vaccines before and after chimeric antigen receptor–modified T-cell therapy

Supplemental data

Soluble urokinase-type plasminogen activator receptor in sickle cell disease–associated chronic kidney disease

Nowah Afangbedji,Namita Kumari,Sharmin Diaz,Fayuan Wen,James G. Taylor,Sergei Nekhai,Marina Jerebtsova

View Articletitled, Soluble urokinase-type plasminogen activator receptor in sickle cell disease–associated chronic kidney disease

Supplemental data

ERRATUM

Schünemann HJ, Cushman M, Burnett AE, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients. Blood Adv. 2018;2(22):3198-3225.

View Articletitled, Schünemann HJ, Cushman M, Burnett AE, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients. Blood Adv. 2018;2(22):3198-3225.

Supplemental data

Cover Image

Cover Image

Immunostaining of mouse bone marrow shows that endoplasmic reticulum protein 5 (ERp5)–deficient megakaryocytes (green, anti-CD42c Dylight 488) have increased expression of endoplasmic reticulum protein 57 (ERp57) (red, anti-ERp57 + anti-rabbit IgG Alexa 647). Nuclei are stained with Hoechst 33342. ERp5 serves to preserve ER homeostasis in murine megakaryocytes and platelets. See the article by Lay et al.
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Issue Archive

Table of Contents

INSIDE BLOOD ADVANCES

Cord blood power and the definition of success after BMT Clinical Trials & Observations

Curing CLL: one clone at a time Clinical Trials & Observations

CLINICAL TRIALS AND OBSERVATIONS

Cord blood transplantation for nonmalignant disorders: early functional immunity and high survival Clinical Trials & Observations

Cord blood power and the definition of success after BMT Clinical Trials & Observations

Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML Clinical Trials & Observations

Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones Clinical Trials & Observations

HEALTH SERVICES AND OUTCOMES

IMMUNOBIOLOGY AND IMMUNOTHERAPY

LYMPHOID NEOPLASIA

Curing CLL: one clone at a time Clinical Trials & Observations

MYELOID NEOPLASIA

CNL and aCML should be considered as a single entity based on molecular profiles and outcomes Clinical Trials & Observations

Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms Clinical Trials & Observations

Adaptation of Serious Illness Care Program to be delivered via telehealth for older patients with hematologic malignancy Clinical Trials & Observations

PLATELETS AND THROMBOPOIESIS

RED CELLS, IRON, AND ERYTHROPOIESIS

THROMBOSIS AND HEMOSTASIS

TRANSPLANTATION

RESEARCH LETTERS

Humoral and cellular responses to SARS-CoV-2 vaccines before and after chimeric antigen receptor–modified T-cell therapy Clinical Trials & Observations

ERRATUM

Cover Image

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ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Cord blood power and the definition of success after BMT
Clinical Trials & Observations

Curing CLL: one clone at a time
Clinical Trials & Observations

Cord blood transplantation for nonmalignant disorders: early functional immunity and high survival
Clinical Trials & Observations

Cord blood power and the definition of success after BMT
Clinical Trials & Observations

Targeting RARA overexpression with tamibarotene, a potent and selective RARα agonist, is a novel approach in AML
Clinical Trials & Observations

Paired bone marrow and peripheral blood samples demonstrate lack of widespread dissemination of some CH clones
Clinical Trials & Observations

Curing CLL: one clone at a time
Clinical Trials & Observations

CNL and aCML should be considered as a single entity based on molecular profiles and outcomes
Clinical Trials & Observations

Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms
Clinical Trials & Observations

Adaptation of Serious Illness Care Program to be delivered via telehealth for older patients with hematologic malignancy
Clinical Trials & Observations

Humoral and cellular responses to SARS-CoV-2 vaccines before and after chimeric antigen receptor–modified T-cell therapy
Clinical Trials & Observations