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Issue Archive

Volume 7, Issue 1
January 10 2023
Issue Cover

Table of Contents

STIMULUS REPORT

Longitudinal study of 2 patients with cyclic thrombocytopenia, STAT3 and MPL mutations
Haiyu Zhang,May Chien,Yu Hou,William Shomali,Rondeep S. Brar,Chandler Ho,Panpan Han,Danfei Xu,Bing M. Zhang,Xiangqian Guo,Lorna L. Tolentino,Nancy C. Wu,Albert G. Tsai,Jing Jin,Wesley H. Witteles,Zhenping Chen,Parveen Abidi,Diwash Jangam,Madison S. Krieger,Morgan Craig,James B. Bussel,Jason R. Gotlib,James L. Zehnder
View Articletitled, Longitudinal study of 2 patients with cyclic thrombocytopenia, <em>STAT3</em> and <em>MPL</em> mutations
Supplemental data

SYSTEMATIC REVIEWS

Interventions to reduce infections in patients with hematological malignancies: a systematic review and meta-analysis
Khai Li Chai,Jonathan Wong,Robert Weinkove,Anastazia Keegan,Philip Crispin,Simon Stanworth,C. Orla Morrissey,Erica M. Wood,Zoe K. McQuilten
View Articletitled, Interventions to reduce infections in patients with hematological malignancies: a systematic review and meta-analysis
Supplemental data
Toxicity and efficacy of CAR T-cell therapy in primary and secondary CNS lymphoma: a meta-analysis of 128 patients
Michael R. Cook,C. Scott Dorris,Kepher H. Makambi,Yutong Luo,Pashna N. Munshi,Michelle Donato,Scott Rowley,Ayman Saad,Andre Goy,Kieron Dunleavy,Alaa Ali
View Articletitled, Toxicity and efficacy of CAR T-cell therapy in primary and secondary CNS lymphoma: a meta-analysis of 128 patients
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Targets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study
Clinical Trials & Observations
Olga Oleshko,Sonja Werwitzke,Annika Klingberg,Torsten Witte,Hermann Eichler,Robert Klamroth,Katharina Holstein,Christina Hart,Christian Pfrepper,Paul Knöbl,Richard Greil,Peter Neumeister,Birgit M. Reipert,Andreas Tiede
View Articletitled, Targets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study

HEMATOPOIESIS AND STEM CELLS

Integrated flow cytometry and sequencing to reconstruct evolutionary patterns from dysplasia to acute myeloid leukemia
Catia Simoes,Maria-Carmen Chillon,David Martínez-Cuadrón,Maria-José Calasanz,María-Belén Vridiales,Iria Vazquez,Montserrat Hernández-Ruano,Beñat Ariceta,Paula Aguirre-Ruiz,Leire Burgos,Diego Alignani,Sarai Sarvide,Sara Villar,Ana Alfonso Pierola,Felipe Prosper,Rosa Ayala,Joaquin Martínez-López,Juan Miguel Bergua Burgues,Susana Vives,Jose A. Perez-Simon,Maria Garcia-Fortes,Teresa Bernal del Castillo,Mercedes Colorado,Mayte Olave,Juan I. Rodríguez-Gutiérrez,Jorge Labrador,Marcos González,Jesús F. San-Miguel,Miguel Ángel Sanz,Pau Montesinos,Bruno Paiva,on behalf of the Programa para Tratamientos en Hematologia (PETHEMA) Cooperative Study Group
View Articletitled, Integrated flow cytometry and sequencing to reconstruct evolutionary patterns from dysplasia to acute myeloid leukemia
Supplemental data

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15
Rafael Alonso Fernandez,Jessica Encinas Mayoral,Laetitia Pierre-Louis,Yao Yao,Yan Xu,Shidai Mu,Joaquin Martinez-Lopez,Daniel Primo,Takahiro Miyazaki,Rao Prabhala,Kenneth C. Anderson,Willem W. Overwijk,Nikhil C. Munshi,Mariateresa Fulciniti
View Articletitled, Improving NK cell function in multiple myeloma with NKTR-255, a novel polymer-conjugated human IL-15
Supplemental data
Granulocytic myeloid-derived suppressor cells to prevent and treat murine immune-mediated bone marrow failure
Xingmin Feng,Jisoo Kim,Gladys Gonzalez-Matias,Nidhi Aggarwal,Ash Lee Manley,Zhijie Wu,Sabrina Solorzano,Sai Batchu,Shouguo Gao,Jichun Chen,Neal S. Young
View Articletitled, Granulocytic myeloid-derived suppressor cells to prevent and treat murine immune-mediated bone marrow failure
Supplemental data

LYMPHOID NEOPLASIA

Orally bioavailable BTK PROTAC active against wild-type and C481 mutant BTKs in human lymphoma CDX mouse models
Ye Seul Lim,Sun-Mi Yoo,Vineet Patil,Han Wool Kim,Hyun-Hwi Kim,Beomseon Suh,Ji Youn Park,Na-rae Jeong,Chi Hoon Park,Je Ho Ryu,Byung-Hoon Lee,Pilho Kim,Song Hee Lee
View Articletitled, Orally bioavailable BTK PROTAC active against wild-type and C481 mutant BTKs in human lymphoma CDX mouse models
Supplemental data
The immune microenvironment shapes transcriptional and genetic heterogeneity in chronic lymphocytic leukemia
Clare Sun,Yun-Ching Chen,Aina Martinez Zurita,Maria Joao Baptista,Stefania Pittaluga,Delong Liu,Daniel Rosebrock,Satyen Harish Gohil,Nakhle S. Saba,Theresa Davies-Hill,Sarah E. M. Herman,Gad Getz,Mehdi Pirooznia,Catherine J. Wu,Adrian Wiestner
View Articletitled, The immune microenvironment shapes transcriptional and genetic heterogeneity in chronic lymphocytic leukemia
Supplemental data
Genetic and immunohistochemical profiling of NK/T-cell lymphomas reveals prognostically relevant BCOR-MYC association
Naoki Oishi,Akira Satou,Masashi Miyaoka,Ichiro Kawashima,Takahiro Segawa,Kunio Miyake,Kunio Mochizuki,Keita Kirito,Andrew L. Feldman,Naoya Nakamura,Tetsuo Kondo
View Articletitled, Genetic and immunohistochemical profiling of NK/T-cell lymphomas reveals prognostically relevant <em>BCOR</em>-MYC association
Supplemental data

MYELOID NEOPLASIA

U2AF1 and EZH2 mutations are associated with nonimmune hemolytic anemia in myelodysplastic syndromes
Rami Komrokji,Luis E. Aguirre,Najla Al Ali,Mohamad Hussaini,David Sallman,Dana Rollison,Eric Padron
View Articletitled, U2AF1 and EZH2 mutations are associated with nonimmune hemolytic anemia in myelodysplastic syndromes

PLATELETS AND THROMBOPOIESIS

Treatment of congenital thrombocytopenia and decreased collagen reactivity in G6b-B–deficient mice
Alexandra Mazharian,Blandine Maître,Alicia Bornert,Desline Hennequin,Marc Lourenco-Rodrigues,Mitchell J. Geer,Christopher W. Smith,Silke Heising,Michaela Walter,Florian Montel,Lucy S. K. Walker,Henri de la Salle,Steve P. Watson,Christian Gachet,Yotis A. Senis
View Articletitled, Treatment of congenital thrombocytopenia and decreased collagen reactivity in G6b-B–deficient mice
Supplemental data
ADAMTS13 conformation and immunoprofiles in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura
Kazuya Sakai,Masanori Matsumoto,Laure De Waele,Charlotte Dekimpe,Eriko Hamada,Masayuki Kubo,Claudia Tersteeg,Simon F. De Meyer,Karen Vanhoorelbeke
View Articletitled, ADAMTS13 conformation and immunoprofiles in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura
Supplemental data

THROMBOSIS AND HEMOSTASIS

Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells
Christopher V. Carman,Dessislava N. Nikova,Yumiko Sakurai,Jialan Shi,Valerie A. Novakovic,Jan T. Rasmussen,Wilbur A. Lam,Gary E. Gilbert
View Articletitled, Membrane curvature and PS localize coagulation proteins to filopodia and retraction fibers of endothelial cells
Supplemental data

TRANSPLANTATION

Dual inhibition of the MEK/ERK and PI3K/AKT pathways prevents pulmonary GVHD suppressing perivenulitis and bronchiolitis
Hiroyuki Muranushi,Takero Shindo,Toyofumi F Chen-Yoshikawa,Akihiko Yoshizawa,Huong Thi Ngo,Fumiaki Gochi,Hiroshi Date,Akifumi Takaori-Kondo
View Articletitled, Dual inhibition of the MEK/ERK and PI3K/AKT pathways prevents pulmonary GVHD suppressing perivenulitis and bronchiolitis
Supplemental data

RESEARCH LETTERS

Distinguishing STAT3/STAT5B-mutated large granular lymphocyte leukemia from myeloid neoplasms by genetic profiling
Mark Kavesh,Maedeh Mohebnasab,Marcela Riveros Angel,Wei Xie,Philipp W. Raess,Wei Cui,Richard D. Press,Guang Yang,Peng Li
View Articletitled, Distinguishing <em>STAT3/STAT5B</em>-mutated large granular lymphocyte leukemia from myeloid neoplasms by genetic profiling
Supplemental data
Postibrutinib relapse outcomes for patients with marginal zone lymphoma
Narendranath Epperla,Qiuhong Zhao,Sayan Mullick Chowdhury,Lauren Shea,Tamara K. Moyo,Nishitha Reddy,Julia Sheets,David M. Weiner,Praveen Ramakrishnan Geethakumari,Malathi Kandarpa,Ximena Jordan Bruno,Colin Thomas,Michael C. Churnetski,Andrew Hsu,Luke Zurbriggen,Xiao-wei Cherie Tan,Kathryn Lindsey,Joseph Maakaron,Paolo F. Caimi,Pallawi Torka,Celeste Bello,Sabarish Ayyappan,Timothy S. Oh,Reem Karmali,Seo-Hyun Kim,Anna Kress,Shalin Kothari,Yazeed Sawalha,Beth Christian,Kevin A. David,Irl Brian Greenwell,Murali Janakiram,Vaishalee P. Kenkre,Adam J. Olszewski,Jonathon B. Cohen,Neil Palmisiano,Elvira Umyarova,Ryan A. Wilcox,Farrukh T. Awan,Juan Pablo Alderuccio,Stefan K. Barta,Natalie S. Grover,Nilanjan Ghosh,Nancy L. Bartlett,Alex F. Herrera,Geoffrey Shouse
View Articletitled, Postibrutinib relapse outcomes for patients with marginal zone lymphoma
Supplemental data
Risk of posthospital venous thromboembolism in patients with COVID-19 varies by SARS-CoV-2 period and vaccination status
Clinical Trials & Observations
Nareg H. Roubinian,David R. Vinson,Tess Knudson-Fitzpatrick,Dustin G. Mark,Jacek Skarbinski,Catherine Lee,Vincent X. Liu,Ashok P. Pai
View Articletitled, Risk of posthospital venous thromboembolism in patients with COVID-19 varies by SARS-CoV-2 period and vaccination status
First description of the t(3;17)(q27;q21)/IGF2BP2::LSM12 translocation in marginal zone lymphoma
Ramón Diez-Feijóo,Concepción Fernández-Rodríguez,Marta Lafuente,Nieves García-Gisbert,Ana Ferrer,Luis Colomo,Marta Salido,Antonio Salar
View Articletitled, First description of the t(3;17)(q27;q21)/<em>IGF2BP2::LSM12</em> translocation in marginal zone lymphoma
Supplemental data
Reduced FVIII recovery associated with anti-FVIII PEG antibodies after BNT162b2 SARS-CoV-2 vaccination
Carla Valsecchi,Roberta Gualtierotti,Sara Arcudi,Alessandro Ciavarella,Lucia Schiavone,Cristina Novembrino,Simona Maria Siboni,Pier Mannuccio Mannucci,Flora Peyvandi
View Articletitled, Reduced FVIII recovery associated with anti-FVIII PEG antibodies after BNT162b2 SARS-CoV-2 vaccination

ERRATA

Seidizadeh O, Baronciani L, Pagliari MT, et al. Phenotypic and genetic characterizations of the Milan cohort of von Willebrand disease type 2. Blood Adv. 2022; 6(13):4031-4040.
View Articletitled, Seidizadeh O, Baronciani L, Pagliari MT, et al. Phenotypic and genetic characterizations of the Milan cohort of von Willebrand disease type 2. <em>Blood Adv</em>. 2022; 6(13):4031-4040.
Bruscaggin A, Terzi di Bergamo L, Spina V, et al. Circulating tumor DNA for comprehensive noninvasive monitoring of lymphoma treated with ibrutinib plus nivolumab. Blood Adv. 2021;5(22):4674-4685.
View Articletitled, Bruscaggin A, Terzi di Bergamo L, Spina V, et al. Circulating tumor DNA for comprehensive noninvasive monitoring of lymphoma treated with ibrutinib plus nivolumab. <em>Blood Adv</em>. 2021;5(22):4674-4685.
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