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Issue Archive

Volume 1, Issue 25
November 28 2017
Issue Cover

Table of Contents

POINT-COUNTERPOINT

Disease control should be the goal of therapy for WM patients
Clinical Trials & Observations
Efstathios Kastritis,Meletios A. Dimopoulos
View Articletitled, Disease control should be the goal of therapy for WM patients
What should be the goal of therapy for Waldenström macroglobulinemia patients? Complete response should be the goal of therapy
Clinical Trials & Observations
Steven P. Treon,Jorge J. Castillo
View Articletitled, What should be the goal of therapy for Waldenström macroglobulinemia patients? Complete response should be the goal of therapy

EXCEPTIONAL CASE REPORT

Buccal epithelial cells display somatic, bone marrow–derived CALR mutation
Clinical Trials & Observations
Scott R. Gilles,Linda B. Baughn,Matthew L. Schomaker,Elizabeth L. Courville,Andrew C. Nelson,Zohar Sachs
View Articletitled, Buccal epithelial cells display somatic, bone marrow–derived <em>CALR</em> mutation
Supplemental data

STIMULUS REPORT

Changes in bone marrow innate lymphoid cell subsets in monoclonal gammopathy: target for IMiD therapy
Clinical Trials & Observations
Jithendra Kini Bailur,Sameet Mehta,Lin Zhang,Natalia Neparidze,Terri Parker,Noffar Bar,Tara Anderson,Mina L. Xu,Kavita M. Dhodapkar,Madhav V. Dhodapkar
View Articletitled, Changes in bone marrow innate lymphoid cell subsets in monoclonal gammopathy: target for IMiD therapy
Supplemental data

REVIEW ARTICLES

Mature lymphoid malignancies: origin, stem cells, and chronicity
Simon Husby,Kirsten Grønbæk
View Articletitled, Mature lymphoid malignancies: origin, stem cells, and chronicity
Supplemental data
Minimal residual disease in adult ALL: technical aspects and implications for correct clinical interpretation
Monika Brüggemann,Michaela Kotrova
View Articletitled, Minimal residual disease in adult ALL: technical aspects and implications for correct clinical interpretation
Maintenance of telomere length in AML
Peter M. Lansdorp
View Articletitled, Maintenance of telomere length in AML
Pharmacologic agents to prevent and treat relapse after allogeneic hematopoietic cell transplantation
Robert J. Soiffer,Yi-Bin Chen
View Articletitled, Pharmacologic agents to prevent and treat relapse after allogeneic hematopoietic cell transplantation

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs
Joseph R. Francica,Daniel E. Zak,Caitlyn Linde,Emilio Siena,Carrie Johnson,Michal Juraska,Nicole L. Yates,Bronwyn Gunn,Ennio De Gregorio,Barbara J. Flynn,Nicholas M. Valiante,Padma Malyala,Susan W. Barnett,Pampi Sarkar,Manmohan Singh,Siddhartha Jain,Margaret Ackerman,Munir Alam,Guido Ferrari,Andres Salazar,Georgia D. Tomaras,Derek T. O’Hagan,Alan Aderem,Galit Alter,Robert A. Seder
View Articletitled, Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs
Supplemental data

LYMPHOID NEOPLASIA

CD86 regulates myeloma cell survival
Catherine M. Gavile,Benjamin G. Barwick,Scott Newman,Paola Neri,Ajay K. Nooka,Sagar Lonial,Kelvin P. Lee,Lawrence H. Boise
View Articletitled, CD86 regulates myeloma cell survival
Supplemental data
Blockade of CD7 expression in T cells for effective chimeric antigen receptor targeting of T-cell malignancies
Yi Tian Png,Natasha Vinanica,Takahiro Kamiya,Noriko Shimasaki,Elaine Coustan-Smith,Dario Campana
View Articletitled, Blockade of CD7 expression in T cells for effective chimeric antigen receptor targeting of T-cell malignancies
Supplemental data

Professional illustration by Patrick Lane, ScEYEnce Studios.

Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice
Tomasz Sewastianik,Meng Jiang,Kumar Sukhdeo,Sanjay S. Patel,Kathryn Roberts,Yue Kang,Ahmad Alduaij,Peter S. Dennis,Brian Lawney,Ruiyang Liu,Zeyuan Song,Jessie Xiong,Yunyu Zhang,Madeleine E. Lemieux,Geraldine S. Pinkus,Jeremy N. Rich,David M. Weinstock,Charles G. Mullighan,Norman E. Sharpless,Ruben D. Carrasco
View Articletitled, Constitutive Ras signaling and <em>Ink4a/Arf</em> inactivation cooperate during the development of B-ALL in mice
Supplemental data
The impact of prior malignancies on second malignancies and survival in MM patients: a population-based study
Clinical Trials & Observations
Gudbjörg Jonsdottir,Sigrún H. Lund,Magnus Björkholm,Ingemar Turesson,Malin Hultcrantz,Anna Porwit,Yogesh S. Jethava,Ola Landgren,Sigurdur Y. Kristinsson
View Articletitled, The impact of prior malignancies on second malignancies and survival in MM patients: a population-based study
Early progression of disease as a predictor of survival in chronic lymphocytic leukemia
Clinical Trials & Observations
Inhye E. Ahn,Charles M. Farber,Matthew S. Davids,David L. Grinblatt,Neil E. Kay,Nicole Lamanna,Anthony Mato,Chadi Nabhan,Pavel Kiselev,Arlene S. Swern,E. Dawn Flick,Kristen Sullivan,Jeff P. Sharman,Christopher R. Flowers
View Articletitled, Early progression of disease as a predictor of survival in chronic lymphocytic leukemia
Supplemental data

MYELOID NEOPLASIA

Mesenchymal stem cells expressing osteoprotegerin variants inhibit osteolysis in a murine model of multiple myeloma
Jerome T. Higgs,Joo Hyoung Lee,Hong Wang,Vishnu C. Ramani,Diptiman Chanda,Cherlene Y. Hardy,Ralph D. Sanderson,Selvarangan Ponnazhagan
View Articletitled, Mesenchymal stem cells expressing osteoprotegerin variants inhibit osteolysis in a murine model of multiple myeloma
Supplemental data

THROMBOSIS AND HEMOSTASIS

Recurrent thrombosis in patients with antiphospholipid antibodies and arterial thrombosis on antithrombotic therapy
Clinical Trials & Observations
William G. Jackson,on behalf of the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking,Clara Oromendia,on behalf of the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking,Ozan Unlu,on behalf of the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking,Doruk Erkan,on behalf of the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking,Maria T. DeSancho,on behalf of the Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking
View Articletitled, Recurrent thrombosis in patients with antiphospholipid antibodies and arterial thrombosis on antithrombotic therapy
A clinical audit of thrombophilia testing in pediatric patients with acute thromboembolic events: impact on management
Clinical Trials & Observations
Chakri Gavva,Ravindra Sarode,Ayesha Zia
View Articletitled, A clinical audit of thrombophilia testing in pediatric patients with acute thromboembolic events: impact on management
The lipid peroxidation product 4-hydroxy-2-nonenal induces tissue factor decryption via ROS generation and the thioredoxin system
Shabbir A. Ansari,Usha R. Pendurthi,L. Vijaya Mohan Rao
View Articletitled, The lipid peroxidation product 4-hydroxy-2-nonenal induces tissue factor decryption via ROS generation and the thioredoxin system
Supplemental data
Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry
Clinical Trials & Observations
Donald M. Arnold,Ishac Nazy,Rumi Clare,Anushka M. Jaffer,Brandon Aubie,Na Li,John G. Kelton
View Articletitled, Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry
Supplemental data

TRANSPLANTATION

Allogeneic bone marrow transplant in the absence of cytoreductive conditioning rescues mice with β-thalassemia major
Yongliang Huo,Jonathan R. Lockhart,Shanrun Liu,Suean Fontenard,Mike Berlett,Thomas M. Ryan
View Articletitled, Allogeneic bone marrow transplant in the absence of cytoreductive conditioning rescues mice with β-thalassemia major
Supplemental data

COMMENTARY

Empiric antibiotic use in allogeneic hematopoietic cell transplantation: should we avoid anaerobe coverage?
Clinical Trials & Observations
Yusuke Shono,Marcel R. M. van den Brink
View Articletitled, Empiric antibiotic use in allogeneic hematopoietic cell transplantation: should we avoid anaerobe coverage?
All Issues

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Time to revisit reduced-dose radiotherapy for PCNSL?
Lin A, Brown S, Chinapen S, et al. Patterns of CMV infection after letermovir withdrawal in recipients of posttransplant cyclophosphamide–based transplant. Blood Adv. 2023;7(23):7153-7160.
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Epigenetic features support the diagnosis of B-cell prolymphocytic leukemia and identify 2 clinicobiological subtypes
Retreatment of multiple myeloma with previously refractory drugs

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