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Journal Articles

A Human Fibrinogen Variant with Impaired Staphylococcus Aureus Binding Function Promotes Host Survival during Septicemia in Mice

Oscar Negron, Jaap Koopman, PhD, Miranda Weggeman, PhD, Linda Huisman, PhD, Amanda Stang, Matthew J. Flick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3775.
https://doi.org/10.1182/blood-2018-99-118491
Published: 2018
Journal Articles

Fibrin(ogen)-Pathogen Interactions Support Antimicrobial Host Defense Following Staphylococcus Aureus Peritonitis Infection

Oscar Negron, Carolina Cruz, Matthew J. Flick, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2350.
https://doi.org/10.1182/blood.V130.Suppl_1.2350.2350
Published: 2017
Journal Articles

Extracellular Nucleosome Levels in the Etiopathogenesis of Sepsis Associated Coagulopathy

Amanda Walborn, BS, Priya Patel, BS, Debra Hoppensteadt, PhD, Michael Mosier, MD, Matthew T. Rondina, MD, Jawed Fareed, PhD
Journal: Blood
Blood (2016) 128 (22): 564.
https://doi.org/10.1182/blood.V128.22.564.564
Published: 2016
Journal Articles

Staphylococcus Aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes

Andras Spaan, Tamara Reyes-Robles, Cédric Badiou, Sylvie Cochet, Kristina Boguslawski, Pauline Yoong, Christopher J. Christopher J. Day, Carla J.C de Haas, Kok P.M. van Kessel, François Vandenesch, Michael P. Jennings, Caroline Le Van Kim, Yves Colin Aronovicz, Jos A.G van Strijp, Thomas Henry, Victor J. Torres
Journal: Blood
Blood (2015) 126 (23): 162.
https://doi.org/10.1182/blood.V126.23.162.162
Published: 2015
Journal Articles

Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia

Matthew J. Flick, XinLi Du, Joni M. Prasad, Harini Raghu, Joseph S. Palumbo, Emanuel Smeds, Magnus Höök, Jay L. Degen
Journal: Blood
Blood (2013) 121 (10): 1783–1794.
https://doi.org/10.1182/blood-2012-09-453894
Published: 2013
Journal Articles

Protective T-Cell Responses to Several Recombinant Aspergillus Antigens May Be Detected Since the Onset of the Infection in Patients with Invasive Aspergillosis, and May Be Exploited for Therapeutic Purposes,

Leonardo Potenza, Daniela Vallerini, PhD, Patrizia Barozzi, PhD, Giovanni Riva, MD PhD, Forghieri Fabio, MD PhD, Johan Maertens, MD, Anna Candoni, M.D., Anne Beauvais, Remi Beau, Roberto Marasca, Chiara Quadrelli, PhD, Javier Arroyo, Michel Monod, MD, Monica Morselli, MD, Monica Maccaferri, MD, Ambra Paolini, MD, Patrizia Comoli, MD, Luigina Romani, Franco Narni, MD, Jean Paul Latge, Mario Luppi
Journal: Blood
Blood (2011) 118 (21): 3229.
https://doi.org/10.1182/blood.V118.21.3229.3229
Published: 2011
Journal Articles

Host Prothrombin and Fibrinogen Support S. Aureus Virulence In the Context of Acute Bacteremia

Matthew J. Flick, PhD, Xinli Du, PhD, Leslie Fausnacht, Harini Raghu, Kathryn E Talmage, Keith W Kombrinck, Elizabeth A. Blevins, Eric S. Mullins, MD, Joseph S. Palumbo, MD, Jay L. Degen, PhD
Journal: Blood
Blood (2010) 116 (21): 821.
https://doi.org/10.1182/blood.V116.21.821.821
Published: 2010
Journal Articles

EspP, An Extracellular Serine Protease From Enterohemorrhagic E. Coli , Induces Coagulopathy In Human Whole Blood and Plasma

Kevin H.M. Kuo, MD, Shekeb Khan, MSc, Elena Brnjac, MLT, Emil F. Pai, Dr.rer.nat, Alden E. Chesney, MD
Journal: Blood
Blood (2010) 116 (21): 4416.
https://doi.org/10.1182/blood.V116.21.4416.4416
Published: 2010
Journal Articles

Bacterial Omptins Proteolytically Inactivate Tissue Factor Pathway Inhibitor (TFPI).

Thomas H. Yun, BA, Jessica Cott, BS, Richard I. Tapping, PhD, James M. Slauch, PhD, James H. Morrissey, PhD
Journal: Blood
Blood (2007) 110 (11): 1739.
https://doi.org/10.1182/blood.V110.11.1739.1739
Published: 2007
Journal Articles

Trafficking of the major virulence factor to the surface of transfected P falciparum –infected erythrocytes

Ellen Knuepfer, Melanie Rug, Nectarios Klonis, Leann Tilley, Alan F. Cowman
Journal: Blood
Blood (2005) 105 (10): 4078–4087.
https://doi.org/10.1182/blood-2004-12-4666
Published: 2005
Includes: Multimedia, Supplemental data
Journal Articles

Plasminogen Is a Critical Host Pathogenicity Factor for Group A Streptococcal Infection.

Hongmin Sun, PHD, Ulrika Ringdahl, PHD, Jonathon W. Homeister, MD, William P. Fay, MD, N. Cary Engleberg, MD, Angela Y. Yang, MS, Laura S. Rozek, PHD, Xixi Wang, Ulf Sjobring, PHD, David Ginsburg, MD
Journal: Blood
Blood (2004) 104 (11): 687.
https://doi.org/10.1182/blood.V104.11.687.687
Published: 2004
Journal Articles

Staphylococcus Epidermidis Induced Platelet Aggregation Is Mediated by the Fibrinogen Binding Surface Protein SdrG.

Marian P. Brennan, BSc., Marc Devocelle, Ph.D., Timothy J. Foster, Ph.D., Dermot Cox, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 3532.
https://doi.org/10.1182/blood.V104.11.3532.3532
Published: 2004