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Journal Articles

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

Xiuli Wang, PhD, Miriam Walter, Ryan Urak, Laura Lim, Vibhuti Vyas, MS, Sally Mokhtari, PhD, Don J. Diamond, PhD, Angelo Cardoso, PhD, John Zaia, MD, Stephen J. Forman, MD, Ryotaro Nakamura, MD

Blood (2019) 134 (Supplement_1): 3247.

https://doi.org/10.1182/blood-2019-131843

Published: 2019

Journal Articles

Vaccination with a DNA and MVA ‘Prime-Boost’ Regimen Induces Strong CD8 + T-Cell Responses Against the Immunodominant Minor Histocompatibility Antigen, HA-1: Results of a First-in-Man Phase I Clinical Trial

Charlotte F Inman, BVSc, PhD, Suzy A Eldershaw, BSc. (Hons.), PhD, Hayden Pearce, BSc. (Hons.), PhD, Ben E Abbotts, BSc. (Hons.), MSc., Mirjana Sirovica, BSc(Hons), MSc, Paul Ferguson, MD PhD MRCP, Donna L Walsh, Dip(HE), BSc., Jane Nunnick, BSC. (Hons.), MSc., Shamyla Siddique, BSc.(Hons.), MPhil, Paul Moss, MBBS, PhD FRCP, Ram K Malladi, FRCPath

Blood (2017) 130 (Supplement 1): 1908.

https://doi.org/10.1182/blood.V130.Suppl_1.1908.1908

Published: 2017

Journal Articles

Safety, Maximum Tolerated Dose and Immunogenicity of CMV-MVA-Triplex in Healthy Volunteers with or without Prior Immunity to CMV and Vaccinia

Don J. Diamond, PhD, Corinna La Rosa, PhD, Jeffrey Longmate, PhD, Joy Martinez, Qiao Zhou, Theodora Kaltcheva, PhD, Jennifer Drake, Mary Carroll, Sanjeet Dadwal, MD, Ibrahim Aldoss, MD, Ryotaro Nakamura, MD, John A. Zaia, MD

Blood (2015) 126 (23): 3108.

https://doi.org/10.1182/blood.V126.23.3108.3108

Published: 2015

Journal Articles

Thymidine Kinase-Deleted, let7a-Regulated Vaccinia Virus Specifically Infects and Lyses Myeloma Cells in a Mouse Myeloma Model

Muneyoshi Futami, MDPhD, Kota Sato, MD, Takafumi Nakamura, PhD, Arinobu Tojo, MD PhD

Blood (2014) 124 (21): 2082.

https://doi.org/10.1182/blood.V124.21.2082.2082

Published: 2014

Journal Articles

Transduction of Malignant Plasma Cells with Three Costimulatory Molecules (TRICOM) Elicits Myeloma-Specific Immune Response in Vitro – a Promising Strategy for Immunotherapy

Katarina Luptakova, MD, Heidi Mills, Jacalyn Rosenblatt, MD, Dina Stroopinsky, PhD, Turner Kufe, Baldev Vasir, PhD, Jon E. Arnason, MD, Dimitrios Tzachanis, MD, PhD, Robin Joyce, MD, James D. Levine, MD, Donald Kufe, MD, David Avigan, MD

Blood (2012) 120 (21): 1908.

https://doi.org/10.1182/blood.V120.21.1908.1908

Published: 2012

Journal Articles

Combining Oncolytic Vaccinia Virotherapy with Adoptive T Cell Therapy,

Minhtran Charlotte Ngo, Jun Ando, MD, PhD, Ann M. Leen, PhD, Caroline Breitbach, PhD, Anne Moon, David Kirn, MD, John Bell, PhD, Cliona M. Rooney, PhD

Blood (2011) 118 (21): 4042.

https://doi.org/10.1182/blood.V118.21.4042.4042

Published: 2011

Journal Articles

Immune reconstitution is preserved in hematopoietic stem cell transplantation coadministered with regulatory T cells for GVHD prevention

Aline Gaidot, Dan Avi Landau, Gaëlle Hélène Martin, Olivia Bonduelle, Yenkel Grinberg-Bleyer, Diana Matheoud, Sylvie Grégoire, Claude Baillou, Béhazine Combadière, Eliane Piaggio, José Laurent Cohen

Blood (2011) 117 (10): 2975–2983.

https://doi.org/10.1182/blood-2010-08-299974

Published: 2011

Includes: Supplemental data

Journal Articles

Modified Vaccinia Ankara Virus (MVA) Induces a Th1-Polarized Immune Response in Antigen-Presenting Cells (APCs).

Christin Flechsig, Yasemin Suezer, DVM, Markus Kapp, MD, Gerd Sutter, DVM, Hermann Einsele, MD, Götz Ulrich Grigoleit, MD

Blood (2009) 114 (22): 4650.

https://doi.org/10.1182/blood.V114.22.4650.4650

Published: 2009

Journal Articles

SNP-Arrays Provide New Insights Into the Pathogenesis of Post-Transplant Diffuse Large B-Cell Lymphoma (PT-DLBCL).

Andrea Rinaldi, Daniela Capello, PhD, Marta Scandurra, Timothy C. Greiner, MS, MD, Wing C. Chan, Davide Rossi, MD, Govind Bhagat, Marco Paulli, MD, Giorgio Inghirami, Maurilio Ponzoni, Santiago Montes Moreno, Miguel A. Piris, MD, Michael Mian, MD, Paola M.V. Rancoita, Emanuele Zucca, Riccardo Dalla-Favera, Gianluca Gaidano, MD, Ivo Kwee, Francesco Bertoni, MD

Blood (2009) 114 (22): 444.

https://doi.org/10.1182/blood.V114.22.444.444

Published: 2009

Journal Articles

A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

Michael Quigley, Jennifer Martinez, Xiaopei Huang, Yiping Yang

Blood (2009) 113 (10): 2256–2264.

https://doi.org/10.1182/blood-2008-03-148809

Published: 2009

Includes: Supplemental data

Journal Articles

Pre-Clinical Development of a Subunit Vaccine Expressing an IE1-IE2 Fusion Protein of HCMV.

Zhongde Wang, PHD, Wendy Zhou, PHD, MD, Tumul Srivastava, PHD, Corinna La Rosa, PHD, Stephen J. Forman, MD, John A. Zaia, MD, Don J. Diamond, PhD

Blood (2007) 110 (11): 165.

https://doi.org/10.1182/blood.V110.11.165.165

Published: 2007

Journal Articles

Stimulation of Anti-Tumor Immunity Using Dendritic Cells Transduced with Fowl Pox Vector Expressing MUC-1 and Costimulatory Molecules (PANVAC-F).

Baldev Vasir, PhD, Corrine Lenahan, MD, Jacalyn Rosenblatt, MD, Adam Bissonnette, Zekui Wu, MD, Donald Kufe, MD, David Avigan, MD

Blood (2006) 108 (11): 5209.

https://doi.org/10.1182/blood.V108.11.5209.5209

Published: 2006

Journal Articles

Vaccine Properties of a Novel Marker Gene-Free Recombinant Modified Vaccinia Ankara (MVA) Expressing Immunodominant CMV Antigens.

Don J. Diamond, PhD, Zhongde Wang, PhD, Corinna La Rosa, PhD, Tumul Srivastava, PHD, Wendy Zhou, MD, PHD, Zhongqi Li, PhD, Heang Ly, Tamineh Akbarnejad, MS, Aparna Krishnan, MS, William J. Britt, MD

Blood (2006) 108 (11): 2858.

https://doi.org/10.1182/blood.V108.11.2858.2858

Published: 2006

Journal Articles

Early acquisition of cytolytic function and transcriptional changes in a primary CD8 + T-cell response in vivo

Christopher Chiu, Adrian G. Heaps, Vincenzo Cerundolo, Andrew J. McMichael, Charles R. Bangham, Margaret F. C. Callan

Blood (2006) 109 (3): 1086–1094.

https://doi.org/10.1182/blood-2006-03-011643

Published: 2006

Includes: Supplemental data

Journal Articles

Development and Immunologic Characterization of Multi-Antigen Expressing Attenuated Poxviruses for Immunotherapy of CMV Infection in HSCT Recipients.

Don J. Diamond, PhD, Zhongde Wang, PhD, Corinna La Rosa, PhD, Goetz U. Grigoleit, MD, Angelo Mandarino, PhD, Simon F. Lacey, PhD, Holger Ludwig, PhD, William J. Britt, MD, Gerd Sutter, PhD, Hermann Einsele, MD

Blood (2005) 106 (11): 480.

https://doi.org/10.1182/blood.V106.11.480.480

Published: 2005

Journal Articles

Rapid Ex Vivo Expansion of CMV Specific CTL Suitable for Clinical Immunotherapy Using CpG-DNA Matured PBMC Infected with Recombinant MVA.

Don J. Diamond, PhD, Zhongde Wang, PhD, Simon F. Lacey, PhD, Corinna La Rosa, PhD

Blood (2004) 104 (11): 5102.

https://doi.org/10.1182/blood.V104.11.5102.5102

Published: 2004

Journal Articles

Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells

Jean Francois Fonteneau, Daniel G. Kavanagh, Margareta Lirvall, Catherine Sanders, Timothy L. Cover, Nina Bhardwaj, Marie Larsson

Blood (2003) 102 (13): 4448–4455.

https://doi.org/10.1182/blood-2003-06-1801

Published: 2003

Journal Articles

Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens

Bin Zhong, Kun Jiang, Danielle L. Gilvary, Pearlie K. Epling-Burnette, Connie Ritchey, Jinhong Liu, Rosalind J. Jackson, Elizabeth Hong-Geller, Sheng Wei

Blood (2003) 101 (8): 3240–3248.

https://doi.org/10.1182/blood-2001-12-0180

Published: 2003

Journal Articles

Induction of Epstein-Barr Virus-Specific Cytotoxic T-Lymphocyte Responses Using Dendritic Cells Pulsed With EBNA-3A Peptides or UV-Inactivated, Recombinant EBNA-3A Vaccinia Virus

Marion Subklewe, Ann Chahroudi, Alan Schmaljohn, Michael G. Kurilla, Nina Bhardwaj, Ralph M. Steinman

Blood (1999) 94 (4): 1372–1381.

https://doi.org/10.1182/blood.V94.4.1372

Published: 1999

Journal Articles

Generation of primary antigen-specific human cytotoxic T lymphocytes in human/mouse radiation chimera

H Segall, I Lubin, H Marcus, A Canaan, Y Reisner

Blood (1996) 88 (2): 721–730.

https://doi.org/10.1182/blood.V88.2.721.bloodjournal882721

Published: 1996

NARROW

Large-Scale Manufacturing of CMV-CD19CAR T Cells and Characterization of Their Biologic and Immunologic Properties

Vaccination with a DNA and MVA ‘Prime-Boost’ Regimen Induces Strong CD8 + T-Cell Responses Against the Immunodominant Minor Histocompatibility Antigen, HA-1: Results of a First-in-Man Phase I Clinical Trial

Safety, Maximum Tolerated Dose and Immunogenicity of CMV-MVA-Triplex in Healthy Volunteers with or without Prior Immunity to CMV and Vaccinia

Thymidine Kinase-Deleted, let7a-Regulated Vaccinia Virus Specifically Infects and Lyses Myeloma Cells in a Mouse Myeloma Model

Transduction of Malignant Plasma Cells with Three Costimulatory Molecules (TRICOM) Elicits Myeloma-Specific Immune Response in Vitro – a Promising Strategy for Immunotherapy

Combining Oncolytic Vaccinia Virotherapy with Adoptive T Cell Therapy,

Immune reconstitution is preserved in hematopoietic stem cell transplantation coadministered with regulatory T cells for GVHD prevention

Modified Vaccinia Ankara Virus (MVA) Induces a Th1-Polarized Immune Response in Antigen-Presenting Cells (APCs).

SNP-Arrays Provide New Insights Into the Pathogenesis of Post-Transplant Diffuse Large B-Cell Lymphoma (PT-DLBCL).

A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

Pre-Clinical Development of a Subunit Vaccine Expressing an IE1-IE2 Fusion Protein of HCMV.

Stimulation of Anti-Tumor Immunity Using Dendritic Cells Transduced with Fowl Pox Vector Expressing MUC-1 and Costimulatory Molecules (PANVAC-F).

Vaccine Properties of a Novel Marker Gene-Free Recombinant Modified Vaccinia Ankara (MVA) Expressing Immunodominant CMV Antigens.

Early acquisition of cytolytic function and transcriptional changes in a primary CD8 + T-cell response in vivo

Development and Immunologic Characterization of Multi-Antigen Expressing Attenuated Poxviruses for Immunotherapy of CMV Infection in HSCT Recipients.

Rapid Ex Vivo Expansion of CMV Specific CTL Suitable for Clinical Immunotherapy Using CpG-DNA Matured PBMC Infected with Recombinant MVA.

Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells

Human neutrophils utilize a Rac/Cdc42-dependent MAPK pathway to direct intracellular granule mobilization toward ingested microbial pathogens

Induction of Epstein-Barr Virus-Specific Cytotoxic T-Lymphocyte Responses Using Dendritic Cells Pulsed With EBNA-3A Peptides or UV-Inactivated, Recombinant EBNA-3A Vaccinia Virus

Generation of primary antigen-specific human cytotoxic T lymphocytes in human/mouse radiation chimera

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American Society of Hematology

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American Society of Hematology

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