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Journal Articles

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

Yamamoto Keita, MD, Susumu Goyama, MD PhD, Shuhei Asada, MD PhD, Takeshi Fujino, MD, Tomofusa Fukuyama, MD PhD, Yosuke Tanaka, MD, Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Seishi Ogawa, MD PhD, Reina Onoguchi, PhD, Nobuyoshi Akimitsu, PhD, Toshio Kitamura, MD PhD

Blood (2019) 134 (Supplement_1): 2514.

https://doi.org/10.1182/blood-2019-125472

Published: 2019

Journal Articles

CK2 Inhibitor CX4945 Shows Strong In Vivo Anti Leukemia Effect in AML Via Augmented Ikaros-Mediated Regulation of Global Epigenetic Landscape

Chandrika Gowda, MBBS, Chunhua Song, MD, Sadie Steffens, PhD, Yali Ding, PhD, Bo Zhang, Feng Yue, PhD, Soumya Iyer, PhD, Pavan kumar Dhanyamraju, PhD, Jonathon Payne, Morgann Reed, BS, Kimberly J. Payne, PhD, Sinisa Dovat, MD PhD

Blood (2019) 134 (Supplement_1): 2522.

https://doi.org/10.1182/blood-2019-131200

Published: 2019

Journal Articles

Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes

Grace A Ward, BS, Kathy McGraw, PhD, Amy F McLemore, M.S., Nghi B Lam, M.S., Hsin-An Hou, Benjamin S. Meyer, Alan F. List, MD

Blood (2019) 134 (Supplement_1): 774.

https://doi.org/10.1182/blood-2019-122358

Published: 2019

Journal Articles

Gfi1 Upregulates c-Myc Expression and Promotes c-Myc-Driven Cell Proliferation

Yangyang Zhang, MD, Fan Dong, MD PhD

Blood (2019) 134 (Supplement_1): 3769.

https://doi.org/10.1182/blood-2019-124833

Published: 2019

Journal Articles

Arsenic Trioxide Synergistically Enhances the Antileukemia Activity of Bcl-2 Inhibitor ABT-199 in Acute Myeloid Leukemia

Sha Liu, Lin Chen, MD, Xiaojiao Wang, Ruihua Mi, Qingsong Yin, Ruihua Fan, Xudong Wei, PhD

Blood (2019) 134 (Supplement_1): 2555.

https://doi.org/10.1182/blood-2019-129543

Published: 2019

Journal Articles

Suicide Gene Therapy with a CD33 Targeted AAV6 Vector Expressing an Inducible Caspase-9 Suicide Gene Is Therapeutic in a Xenotransplantation Model of Acute Myeloid Leukemia

Nusrat Khan, MSc, Sridhar Bammidi, Jayandharan Giridhara Rao, PhD

Blood (2019) 134 (Supplement_1): 3351.

https://doi.org/10.1182/blood-2019-125222

Published: 2019

Journal Articles

KMT2E-Mediated Epigenetic Reprogramming Promotes the Sensitivity to All-Trans Retinoic Acid and Increases the Granulocytic Differentiation in AML Cells

Luciana Yamamoto Almeida, PhD, Isabel Weinhäuser, MSc, Diego Antonio Pereira-Martins, MSc, Josiane Lilian Schiavinato, PhD, Patrícia Vianna Bonini Palma, BSc, Camila Bonaldo, Cleide Lucia Silva, MSc, Juliana Oliveira Poltronieri, MSc, Larissa Cândido, MSc, Antonio R. Lucena-Araujo, PhD, Eduardo Magalhães Rego, MD PhD

Blood (2018) 132 (Supplement 1): 3838.

https://doi.org/10.1182/blood-2018-99-118478

Published: 2018

Journal Articles

Functional Screening for Pathways Regulating Chemoresistance and Sensitivity in Leukemia Stem Cells

Konstantinos Mintzas, MSc, Arnold Kloos, Razif Gabdoulline, Renate Schottmann, Simon Danisch, PhD, Renata Stripecke, Prof., Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD

Blood (2018) 132 (Supplement 1): 3933.

https://doi.org/10.1182/blood-2018-99-112373

Published: 2018

Journal Articles

Venetoclax Synergistically Enhances the Antileukemic Activity of Imipridone ONC213, a Novel Imipridone ONC201 Analog, in Acute Myeloid Leukemia

Yongwei Su, Xinyu Li, Holly Edwards, BS, Lisa Polin, PhD, Juiwanna Kushner, Sijana H Dzinic, PhD, Katie Hege, Yu Fukuda, John D. Schuetz, PhD, Joshua E. Allen, PhD, Martin Stogniew, Varun Vijay Prabhu, BPharm, MS, PhD, Jeffrey W. Taub, MD, Hai Lin, MD, Yubin Ge, PhD

Blood (2018) 132 (Supplement 1): 3936.

https://doi.org/10.1182/blood-2018-99-116997

Published: 2018

Journal Articles

The Genes for Tissue Factor F3 and Nuclear Receptor 4A Are Down-Regulated in Early Death Acute Promyelocytic Leukemia Patients

Miriam Frech, PhD, Kathleen Stabla, Andrea Nist, PhD, Marco Mernberger, PhD, Heidi Altmann, PhD, Uwe Platzbecker, Christian Thiede, MD, Prema Erramsetti, Sabine Teichler, PhD, Cornelia Brendel, MD, Richard F. Schlenk, MD, Thorsten Stiewe, MD, Andreas Neubauer, MD

Blood (2018) 132 (Supplement 1): 3902.

https://doi.org/10.1182/blood-2018-99-112978

Published: 2018

Journal Articles

Prostaglandin E2 Stimulates CREB-Mediated Modification of Histone Variant Nucleosomes at Enhancers to Promote Hematopoietic Stem Cell Fate

Audrey Sporrij, MSc, Eva M. Fast, PhD, Brejnev Muhire, PhD, Margot Manning, BA, Marian Kalocsay, PhD, Robert E. Kingston, PhD, Michael Y. Tolstorukov, PhD, Leonard I. Zon, MD

Blood (2018) 132 (Supplement 1): 530.

https://doi.org/10.1182/blood-2018-99-115232

Published: 2018

Journal Articles

Functional Analysis of CD99 Upregulation in Acute Myeloid Leukemia

Vijaya Pooja Vaikari, MS, Jiawen Yang, BS, Mojtaba Akhtari, MD, Houda Alachkar, PharmD, PhD

Blood (2018) 132 (Supplement 1): 5129.

https://doi.org/10.1182/blood-2018-99-120348

Published: 2018

Journal Articles

A Potential Mechanism for the Antioxidant Compound Kushen Injection Targeting the ROS Signaling Pathway in Acute Myeloid Leukemia

Yanxia Jin, PhD, Qian Yang, Li Liang, Lu Ding, Yuxing Liang, Dongdong Zhang, Tian Yang, Mingfeng Zhao, MD PhD, Fuling Zhou

Blood (2018) 132 (Supplement 1): 5221.

https://doi.org/10.1182/blood-2018-99-114066

Published: 2018

Journal Articles

Mass Spectrometry-Based Immunopeptidome Analysis of Acute Myeloid Leukemia Cells Under Decitabine Treatment Delineates Induced Presentation of Cancer/Testis Antigens on HLA Class I Molecules

Jens Bauer, Nora Zieger, Annika Nelde, Leon Bichmann, Helmut R. Salih, MD, Lothar Kanz, Hans-Georg Rammensee, Stefan Stevanovic, Juliane S. Walz

Blood (2018) 132 (Supplement 1): 5223.

https://doi.org/10.1182/blood-2018-99-113357

Published: 2018

Journal Articles

The HACE1-NRF2 Axis a Novel Target in Acute Myeloid Leukemia

Andoni Garitano-Trojaola, PhD, Eva Teufel, Nadine Rodhes, Jennifer Kreckel, Thorsten Stuehmer, Matteo Claudio Da Via', MD, Santiago Barrio Garcia, PhD, Torsten Haferlach, MD, Raoul Tibes, Harald Wajant, Andreas Rosenwald, Hermann Einsele, MD, K. Martin Kortüm, MD

Blood (2018) 132 (Supplement 1): 5132.

https://doi.org/10.1182/blood-2018-99-118270

Published: 2018

Journal Articles

Development and Characterisation of an in Vitro Model of Multiple Myeloma

Thomas Lewis, BSc, Elisabeth Jane Walsby, PhD, Stephen Man, Christopher Fegan, Chris Pepper, BSc, PhD

Blood (2018) 132 (Supplement 1): 4505.

https://doi.org/10.1182/blood-2018-99-111842

Published: 2018

Journal Articles

Endoplasmic Reticulum Stress Signaling Comprises a G9a Inhibitor Tolerance Pathway and PERK Inhibition Increases Anti-Leukemia Activity of G9a Inhibitor in Leukemia Cells and Leukemia Stem-like Cells

Jieun Jang, MD, Ju-In Eom, Hoi-kyung Jeung, So-Young Seol, Haerim Chung, MD, Yu Ri Kim, MD, June-Won Cheong, MDPhD, Yoo Hong Min, MD PhD

Blood (2018) 132 (Supplement 1): 1360.

https://doi.org/10.1182/blood-2018-99-115814

Published: 2018

Journal Articles

Long Noncoding RNA Loup Interacts with Runx1 and Regulates Long-Range Transcription of PU.1 in Acute Myeloid Leukemia

Bon Q Trinh, PhD, Pu Zhang, MD, Alexander Ebralidze, PhD, Junyan Zhang, Chan-Shuo Guo, Abby Thurm, Henry Yang, PhD, Ying Li, Annalisa Di Ruscio, MD, Daniel G. Tenen, MD

Blood (2018) 132 (Supplement 1): 1281.

https://doi.org/10.1182/blood-2018-99-120252

Published: 2018

Journal Articles

The Novel Small Molecule Inhibitor KS99 Targets AML and Inhibits Stemness Markers STAT3 and ALDH

Charyguly Annageldiyev, Krishne Gowda, Dhimant Desai, Viola Devine, Daniel Brosius, Chandrika Gowda, MBBS, Sinisa Dovat, MD PhD, Shantu Amin, David F. Claxton, MD, Arati Sharma, PhD

Blood (2018) 132 (Supplement 1): 1440.

https://doi.org/10.1182/blood-2018-99-117376

Published: 2018

Journal Articles

Cooperative Effects of a Dnmt Inhibitor and All- Trans Retinoic Acid in an AML Cell Line Model Lacking PML-Rara

Ruth Meier, Gabriele Greve, Christoph Niemöller, Heiko Becker, Tobias Ma, Ralitsa Langova, Björn Grüning, Lars Feuerbach, Daniel B. Lipka, Justus Duyster, Prof., Benedikt Brors, Christoph Plass, Michael Lübbert

Blood (2018) 132 (Supplement 1): 1359.

https://doi.org/10.1182/blood-2018-99-113450

Published: 2018

NARROW

Mutant ASXL1 Disrupts Paraspeckle Formation through Aberrant Interaction with Nono in Hematopoietic Cells

CK2 Inhibitor CX4945 Shows Strong In Vivo Anti Leukemia Effect in AML Via Augmented Ikaros-Mediated Regulation of Global Epigenetic Landscape

Oxidized Mitochondrial DNA Engages TLR9 to Activate the NLRP3 Inflammasome in Myelodysplastic Syndromes

Gfi1 Upregulates c-Myc Expression and Promotes c-Myc-Driven Cell Proliferation

Arsenic Trioxide Synergistically Enhances the Antileukemia Activity of Bcl-2 Inhibitor ABT-199 in Acute Myeloid Leukemia

Suicide Gene Therapy with a CD33 Targeted AAV6 Vector Expressing an Inducible Caspase-9 Suicide Gene Is Therapeutic in a Xenotransplantation Model of Acute Myeloid Leukemia

KMT2E-Mediated Epigenetic Reprogramming Promotes the Sensitivity to All-Trans Retinoic Acid and Increases the Granulocytic Differentiation in AML Cells

Functional Screening for Pathways Regulating Chemoresistance and Sensitivity in Leukemia Stem Cells

Venetoclax Synergistically Enhances the Antileukemic Activity of Imipridone ONC213, a Novel Imipridone ONC201 Analog, in Acute Myeloid Leukemia

The Genes for Tissue Factor F3 and Nuclear Receptor 4A Are Down-Regulated in Early Death Acute Promyelocytic Leukemia Patients

Prostaglandin E2 Stimulates CREB-Mediated Modification of Histone Variant Nucleosomes at Enhancers to Promote Hematopoietic Stem Cell Fate

Functional Analysis of CD99 Upregulation in Acute Myeloid Leukemia

A Potential Mechanism for the Antioxidant Compound Kushen Injection Targeting the ROS Signaling Pathway in Acute Myeloid Leukemia

Mass Spectrometry-Based Immunopeptidome Analysis of Acute Myeloid Leukemia Cells Under Decitabine Treatment Delineates Induced Presentation of Cancer/Testis Antigens on HLA Class I Molecules

The HACE1-NRF2 Axis a Novel Target in Acute Myeloid Leukemia

Development and Characterisation of an in Vitro Model of Multiple Myeloma

Endoplasmic Reticulum Stress Signaling Comprises a G9a Inhibitor Tolerance Pathway and PERK Inhibition Increases Anti-Leukemia Activity of G9a Inhibitor in Leukemia Cells and Leukemia Stem-like Cells

Long Noncoding RNA Loup Interacts with Runx1 and Regulates Long-Range Transcription of PU.1 in Acute Myeloid Leukemia

The Novel Small Molecule Inhibitor KS99 Targets AML and Inhibits Stemness Markers STAT3 and ALDH

Cooperative Effects of a Dnmt Inhibitor and All- Trans Retinoic Acid in an AML Cell Line Model Lacking PML-Rara

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American Society of Hematology

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American Society of Hematology

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