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Journal Articles

The Markedly Increased PAI1 in Obesity Induces a Compensatory Increase of Hepatocyte Tpa Expression By Activating a LRP1-CREB1 Pathway

Ze Zheng, MBBS, PhD, Keiko Nakamura, MD, Shana Gershbaum, Ira Tabas, MD PhD

Blood (2019) 134 (Supplement_1): 3625.

https://doi.org/10.1182/blood-2019-129271

Published: 2019

Journal Articles

Establishing a Link between Zinc Homeostasis and Globin Gene Expression

Oluwaseun Olaiya, DO, Halyna Fedosyuk, MS, Lesya V Novikova, PhD, Matthew P Parker, BS, Kenneth R Peterson, PhD

Blood (2019) 134 (Supplement_1): 3578.

https://doi.org/10.1182/blood-2019-130758

Published: 2019

Journal Articles

Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing By Self-Renewing Hematopoietic Stem and Progenitor Cells

Tomer Itkin, PhD, Chaitanya R Badwe, PhD, Sean Houghton, MSc, Yang Lin, PhD, Ying Liu, PhD, Peipei Guo, PhD, Jesus M Gomez-Salinero, PhD, Fuqiang Geng, PhD, Jae-Hung Shieh, PhD, David Redmond, PhD, Yen-Michael S. Hsu, MD PhD, Brandon Hadland, MD PhD, Shahin Rafii, MD

Blood (2019) 134 (Supplement_1): 725.

https://doi.org/10.1182/blood-2019-126190

Published: 2019

Journal Articles

Efficacy and Safety of Daily All-Trans Retinoic Acid Monotherapy As Maintenance Therapy for Acute Promyelocytic Leukemia

Yoo Jin Lee, MD PhD, Seo-Yeon Ahn, MD, Jae-Cheol Jo, MD PhD, Yunsuk Choi, MD, Ji Hyun Lee, MD PhD

Blood (2019) 134 (Supplement_1): 3898.

https://doi.org/10.1182/blood-2019-125671

Published: 2019

Journal Articles

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Amin Sobh, PhD, Charlotte Kaestner, Alberto Riva, PhD, Jonathan D. Licht, MD

Blood (2019) 134 (Supplement_1): 3757.

https://doi.org/10.1182/blood-2019-125951

Published: 2019

Journal Articles

Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations

Sravanti Rangaraju, MBBS, Silvia Marino, PhD, G. David Roodman, MD PhD, Larry D. Cripe, MD, Baskar Ramdas, PhD, Lakshmi Reddy Palam, PhD, Katie J Sargent, RN, Hamid Sayar, MD MSc, Heiko Konig, MD PhD, Reuben Kapur, PhD, H. Scott Boswell, MD

Blood (2019) 134 (Supplement_1): 5051.

https://doi.org/10.1182/blood-2019-124384

Published: 2019

Journal Articles

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Kamaleldin E Elagib, PhDMBBS, Ashton Brock, PhD, Goar Mosoyan, Cara Clementelli, Lorrie L Delehanty, BS, Alexandra Pacheco-Benichou, Corinne Fruit, Thierry Besson, PhD, Stephen Morris, MD, Koji Eto, MD, Camelia Iancu-Rubin, PhD, Adam N Goldfarb, MD

Blood (2019) 134 (Supplement_1): 3250.

https://doi.org/10.1182/blood-2019-129049

Published: 2019

Journal Articles

Oxidative Phosphorylation Regulated By PGC-1α Promotes Multiple Myeloma Progression

Yu Xiang, MD, Bin Fang, MD, Yilin Liu, MD, Siqi Yan, MD, Yicheng Zhang, Tao Guo, MD PhD

Blood (2019) 134 (Supplement_1): 5524.

https://doi.org/10.1182/blood-2019-127807

Published: 2019

Journal Articles

A CRISPR/Cas9-Generated Murine Model Reveals Cooperation between BCR Signaling and CDKN2A/2B and TP53 Disruption in Richter Syndrome

Supriya Chakraborty, PhD, Ilaria Fortunati, BS, Claudio Martines, MS, Brijesh Yadav, PhD, Marija Dimishkovska, PhD, Idanna Innocenti, MD PhD, Rosa Fazio, BS, Giovanni D'Arena, MD, Aleksandar Dimovski, MD PhD, Luca Laurenti, MD, Dimitar G Efremov, MD PhD

Blood (2019) 134 (Supplement_1): 4278.

https://doi.org/10.1182/blood-2019-128425

Published: 2019

Journal Articles

Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia

Anna McCarter, BS, Ran Yan, Amparo Serna Alarcon, Catherine Chang, Erin Kim, Cher Sha, Yiran Liu, Qing Wang, PhD, Luke F. Peterson, PhD, Rork Kuick, Russell Ryan, MD, Moshe Talpaz, MD, Linda Samuelson, PhD, Michael Ostrowski, PhD, Mark Y Chiang, MD PhD

Blood (2018) 132 (Supplement 1): 2595.

https://doi.org/10.1182/blood-2018-99-111376

Published: 2018

Journal Articles

Combined Targeting of Bcl-2 and XPO1 Overcomes Acquired Resistance to Tyrosine Kinase Inhibitors in the FLT3-ITD/TKD Double Mutant AML

Yoko Tabe, MD PhD, Kotoko Yamatani, MD, Haeun Yang, Kaori Saito, Yuko Murakami-Tonami, MD, Koya Suzuki, PhD, Weiguo Zhang, MD PhD, Sonoko Kinjo, PhD, Kazuho Ikeo, PhD, Masaki Hosoya, PhD, Kaoru Mogushi, PhD, Shigeo Yamaguchi, Hironori Harada, MD PhD, Takashi Miida, MD PhD, Neil Shah, MD, Marina Y. Konopleva, MD PhD, Yoshihide Hayashizaki, MD PhD, Michael Andreeff, MD PhD

Blood (2018) 132 (Supplement 1): 2640.

https://doi.org/10.1182/blood-2018-99-113195

Published: 2018

Journal Articles

Genetic Modulation of Adenosine-to-Inosine RNA Editing Selectively Disrupts Inflammasome and Extracellular Matrix Genes in Multiple Myeloma

Leslie A Crews, PhD, Phoebe Mondala, BS, Elisa Lazzari, PhD, Gabriel Pineda, PhD, Christina Wu, PhD, Caitlin L. Costello, MD, Catriona Jamieson, MD PhD

Blood (2018) 132 (Supplement 1): 1324.

https://doi.org/10.1182/blood-2018-99-120326

Published: 2018

Journal Articles

An Orchestrated Balance between Mitochondria Biogenesis, Iron-Sulfur Cluster Synthesis and Cellular Iron Acquisition

Ping La, Valentina Ghiaccio, PhD, Jianbing Zhang, PhD, Stefano Rivella

Blood (2018) 132 (Supplement 1): 1048.

https://doi.org/10.1182/blood-2018-99-112198

Published: 2018

Journal Articles

Altering Glycosphingolipid Composition to Improve Multiple Myeloma Bone Complication

Houfu Leng, MSc, DPhil, MBBS, BSc, Adel Ersek, PhD, Emma Morris, DPhil, Beatriz Gamez Molina, PhD, Claire M. Edwards, PhD, Nicole Horwood, PhD

Blood (2018) 132 (Supplement 1): 1942.

https://doi.org/10.1182/blood-2018-99-112237

Published: 2018

Journal Articles

A Genome-Wide CRISPR Screen Implicates MYC Dysregulation in TCF3 - PBX1 B-ALL

Ruth E Cranston, BSc, Paul B Sinclair, PhD, Matthew Bashton, PhD, Matthew P Selby, PhD, Christine J Harrison, PhD FRCPath

Blood (2018) 132 (Supplement 1): 3915.

https://doi.org/10.1182/blood-2018-99-110015

Published: 2018

Journal Articles

Histone Deacetylase Inhibitors Abolish HBZ Protein Expression and Induce Cell Death in HTLV-1 Related Adult T-Cell Leukemia-Lymphoma

Ngoc L Toomey, BS, Juan Carlos Ramos, MD BS

Blood (2017) 130 (Supplement 1): 4012.

https://doi.org/10.1182/blood.V130.Suppl_1.4012.4012

Published: 2017

Journal Articles

Narciclasine Display Preferential Pre-Clinical Activity Against KSHV-Associated Primary Effusion Lymphoma By Targeting MYC Via NF-κB

Ramakrishnan Gopalakrishnan, PhD, Hittu Matta, PhD, Sunju Choi, PhD, Preet M. Chaudhary, MD PhD

Blood (2017) 130 (Supplement 1): 2807.

https://doi.org/10.1182/blood.V130.Suppl_1.2807.2807

Published: 2017

Journal Articles

High-Resolution SNP-Array Profiling of "Ultra-High Risk" CLL Cases Reveals New Recurrent Genomic Alterations

Jennifer Edelmann, MD PhD, Karlheinz Holzmann, Dr. rer. nat., Eugen Tausch, MD, Anna Dolnik, PhD, Tamara J. Blätte, MSc, Stefan Ibach, Dr, Jenny Saub, Daniel Mertens, PhD, Lars Bullinger, MD, Kirsten Fischer, MD, Valentin Goede, MD, John G. Gribben, MDDSc FMedSci, Michael J. Hallek, MD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD PhD

Blood (2017) 130 (Supplement 1): 2992.

https://doi.org/10.1182/blood.V130.Suppl_1.2992.2992

Published: 2017

Journal Articles

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Blood (2017) 130 (Supplement 1): 2678.

https://doi.org/10.1182/blood.V130.Suppl_1.2678.2678

Published: 2017

Journal Articles

Tumor Suppressor, NORE1A (RASSF5) , Is an Icsbp-Dependent Inhibitor of Aberrant Stress Granulopoiesis

Olatundun Williams, MD, Elizabeth Hjort, PhD, Ling Bei, MD, Liping Hu, PhD, Elizabeth A. Eklund, MD

Blood (2017) 130 (Supplement 1): 4175.

https://doi.org/10.1182/blood.V130.Suppl_1.4175.4175

Published: 2017

NARROW

The Markedly Increased PAI1 in Obesity Induces a Compensatory Increase of Hepatocyte Tpa Expression By Activating a LRP1-CREB1 Pathway

Establishing a Link between Zinc Homeostasis and Globin Gene Expression

Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing By Self-Renewing Hematopoietic Stem and Progenitor Cells

Efficacy and Safety of Daily All-Trans Retinoic Acid Monotherapy As Maintenance Therapy for Acute Promyelocytic Leukemia

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Cooperativity between Flt3/Syk and Proteasome Inhibitors in Flt3mutant/Wildtype AML, By Acting on the Oxphos and Wnt Endpoints of Syk and p62SQSTM1 Pathways Prohibits Protective Autophagy; While Downregulation of NRF2, NQO1, Jun, and b-Catenin Bypasses Interfering RAS or WT1 Co-Mutations

Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming"

Oxidative Phosphorylation Regulated By PGC-1α Promotes Multiple Myeloma Progression

A CRISPR/Cas9-Generated Murine Model Reveals Cooperation between BCR Signaling and CDKN2A/2B and TP53 Disruption in Richter Syndrome

Ets1 Enhances Context-Dependent Notch1 Activity in T-Cell Leukemia

Combined Targeting of Bcl-2 and XPO1 Overcomes Acquired Resistance to Tyrosine Kinase Inhibitors in the FLT3-ITD/TKD Double Mutant AML

Genetic Modulation of Adenosine-to-Inosine RNA Editing Selectively Disrupts Inflammasome and Extracellular Matrix Genes in Multiple Myeloma

An Orchestrated Balance between Mitochondria Biogenesis, Iron-Sulfur Cluster Synthesis and Cellular Iron Acquisition

Altering Glycosphingolipid Composition to Improve Multiple Myeloma Bone Complication

A Genome-Wide CRISPR Screen Implicates MYC Dysregulation in TCF3 - PBX1 B-ALL

Histone Deacetylase Inhibitors Abolish HBZ Protein Expression and Induce Cell Death in HTLV-1 Related Adult T-Cell Leukemia-Lymphoma

Narciclasine Display Preferential Pre-Clinical Activity Against KSHV-Associated Primary Effusion Lymphoma By Targeting MYC Via NF-κB

High-Resolution SNP-Array Profiling of "Ultra-High Risk" CLL Cases Reveals New Recurrent Genomic Alterations

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Tumor Suppressor, NORE1A (RASSF5) , Is an Icsbp-Dependent Inhibitor of Aberrant Stress Granulopoiesis

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American Society of Hematology

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American Society of Hematology

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