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Journal Articles

Targeting Sirt6 with OSS_128167 Displays Anti-Tumor Activities in Diffuse Large B-Cell Lymphoma through Down-Regulation of PI3K Signaling

Juan Yang, MM, Xiangxiang Zhou, MD, Ying Li, MD, Ya Zhang, MD, Xiaosheng Fang, MD, Na Chen, MD, Xin Wang, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5065.
https://doi.org/10.1182/blood-2019-127926
Published: 2019
Journal Articles

SIRT6 As a Potential Therapeutic Target in Diffuse Large B-Cell Lymphoma

Juan Yang, PhD, Ying Li, MD, Ya Zhang, MD, Xiangxiang Zhou, MD, Xin Wang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2862.
https://doi.org/10.1182/blood-2018-99-115823
Published: 2018
Journal Articles

SIRT6 Inhibition As a Novel Approach for Treating Acute Myeloid Leukemia

Michele Cea, MD, Antonia Cagnetta, MD, Debora Soncini, PhD, Paola Minetto, MD, Davide Lovera, MD, Fabio Guolo, MD, Nicoletta Colombo, PhD, Filippo Ballerini, MD, Marino Clavio, MD, Maurizio Miglino, PhD, Marco Gobbi, MD, Roberto M Lemoli, MD
Journal: Blood
Blood (2016) 128 (22): 5222.
https://doi.org/10.1182/blood.V128.22.5222.5222
Published: 2016
Journal Articles

Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells

Michele Cea, Antonia Cagnetta, Sophia Adamia, Chirag Acharya, Yu-Tzu Tai, Mariateresa Fulciniti, Hiroto Ohguchi, Aditya Munshi, Prakrati Acharya, Manoj K. Bhasin, Lei Zhong, Ruben Carrasco, Fiammetta Monacelli, Alberto Ballestrero, Paul Richardson, Marco Gobbi, Roberto M. Lemoli, Nikhil Munshi, Teru Hideshima, Alessio Nencioni, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2016) 127 (9): 1138–1150.
https://doi.org/10.1182/blood-2015-06-649970
Published: 2016
Includes: Supplemental data
Journal Articles

A Novel Synthetic Lethal Approach Targeting SIRT6 in Acute Myeloid Leukemia

Michele Cea, MD, Antonia Cagnetta, MD, Davide Lovera, MD, Raffaella Grasso, PhD, Nicoletta Colombo, PhD, Micaela Bergamaschi, MD, Sara Aquino, MD, Fabio Guolo, MD, Paola Minetto, MD, Filippo Ballerini, MD, Letizia Canepa, MD, Sophia Adamia, PhD, Alessio Nencioni, Ivana Pierri, MD, Marino Clavio, Maurizio Miglino, PhD, Marco Gobbi, MD, Roberto Massimo Lemoli, MD
Journal: Blood
Blood (2015) 126 (23): 1375.
https://doi.org/10.1182/blood.V126.23.1375.1375
Published: 2015
Journal Articles

Functional Characterization of NAD Dependent De-Acetylases SIRT1 and SIRT2 in B-Cell Chronic Lymphocytic Leukemia (CLL)

Savita Bhalla, PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2015) 126 (23): 4141.
https://doi.org/10.1182/blood.V126.23.4141.4141
Published: 2015
Journal Articles

Role Of Sirtuin-6 In Maintenance Of Genomic Instability In Multiple Myeloma Cells

Michele Cea, MD, Antonia Cagnetta, MD, Mariateresa Fulciniti, PhD, Yu-Tzu Tai, PhD, Chirag Acharya, Mike Zhong, Teru Hideshima, MD, PhD, Marco Gobbi, MD, Nikhil Munshi, MD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2013) 122 (21): 276.
https://doi.org/10.1182/blood.V122.21.276.276
Published: 2013
Journal Articles

Catastrophic NAD + Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE.

Santina Bruzzone, Ph.D., Floriana Fruscione, Sara Morando, Alessandro Poggi, Anna Garuti, Martina Selmo, Tiziana Ferrando, Federica Benvenuto, Michele Cea, MD, Debora Soncini, Eva Moran, Ph.D., Ilaria Rocco, Gabriella Cirmena, Gabriele Zoppoli, MD, Alberto Ballestrero, MD, Ph.D., Bernard Sordat, Franco Patrone, Antonio Uccelli, Alessio Nencioni, MD, Ph.D.
Journal: Blood
Blood (2009) 114 (22): 4732.
https://doi.org/10.1182/blood.V114.22.4732.4732
Published: 2009