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Journal Articles

SGI-110, a Novel Hypomethylating Agent, Induces the WNT Inhibitor Secreted Frizzled Related Protein-2 ( SFRP2 ), and Down Regulates β-Catenin in Acute Myeloid Leukemia (AML) Cells

Michelle Golding, Pragya Srivastava, PhD, Golda Collamat, MS, Smitha R James, MS, Adam R. Karpf, PhD, Michael J. Nemeth, PhD, Elizabeth A Griffiths, MD
Journal: Blood
Blood (2012) 120 (21): 1290.
https://doi.org/10.1182/blood.V120.21.1290.1290
Published: 2012
Journal Articles

Secreted-frizzled related protein 1 is a transcriptional repression target of the t(8;21) fusion protein in acute myeloid leukemia

Chi Keung Cheng, Libby Li, Suk Hang Cheng, Kitty Ng, Natalie P. H. Chan, Rosalina K. L. Ip, Raymond S. M. Wong, Matthew M. K. Shing, Chi Kong Li, Margaret H. L. Ng
Journal: Blood
Blood (2011) 118 (25): 6638–6648.
https://doi.org/10.1182/blood-2011-05-354712
Published: 2011
Includes: Supplemental data
Journal Articles

Secreted Frizzled-Related Protein-3 (sFRP3) Is Produced by Myeloma Cells and Augments Wnt3a-Induced Differentiation of Mesenchymal Stem Cells and OPG Production in Osteoblasts

Ya-Wei Qiang, MD, PhD, Yu Chen, Bo Hu, PhD, Wei Qiang, MD, Christoph Heuck, MD, Shmuel Yaccoby, PhD, Joshua Epstein, DSc, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD
Journal: Blood
Blood (2011) 118 (21): 808.
https://doi.org/10.1182/blood.V118.21.808.808
Published: 2011
Journal Articles

Myeloma Cells Induce Osteoblast Suppression through Sclerostin Secretion

Silvia Colucci, PhD, Giacomina Brunetti, PhD, Angela Oranger, PhD, Giorgio Mori, PhD, Francesca Sardone, PhD, Vincenzo Liso, MD, Paola Curci, MD, Rosanna M Miccolis, MD, Erminia Rinaldi, MD, Giorgina Specchia, MD, Giovanni Passeri, MD, Alberta Zallone, PhD, Rita Rizzi, MD, Maria Grano, PhD
Journal: Blood
Blood (2010) 116 (21): 2961.
https://doi.org/10.1182/blood.V116.21.2961.2961
Published: 2010
Journal Articles

The Wnt Inhibitor sFRP2 Enhances Mesenchymal Stem Cell Engraftment, Granulation Tissue Formation and Myocardial Repair

Maria Paula Alfaro, Matthew Pagni, Alicia Vincent, Michael F. Hill, PhD, Ethan Lee, MD, PhD, Pampee Young, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1365.
https://doi.org/10.1182/blood.V112.11.1365.1365
Published: 2008
Journal Articles

Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

José Román-Gómez, Lucia Cordeu, Xabier Agirre, Antonio Jiménez-Velasco, Edurne San José-Eneriz, Leire Garate, María José Calasanz, Anabel Heiniger, Antonio Torres, Felipe Prosper
Journal: Blood
Blood (2006) 109 (8): 3462–3469.
https://doi.org/10.1182/blood-2006-09-047043
Published: 2006
Journal Articles

Effects of Human Myeloma Cells on WNT Signaling System in Human Bone Marrow Osteoprogenitor Cells.

Nicola Giuliani, Francesca Morandi, Rita Rizzato, Sara Tagliaferri, Vittorio Rizzoli
Journal: Blood
Blood (2005) 106 (11): 2503.
https://doi.org/10.1182/blood.V106.11.2503.2503
Published: 2005
Journal Articles

Myeloma cells suppress bone formation by secreting a soluble Wnt inhibitor, sFRP-2

Takashi Oshima, Masahiro Abe, Jin Asano, Tomoko Hara, Kenichi Kitazoe, Etsuko Sekimoto, Yoichi Tanaka, Hironobu Shibata, Toshihiro Hashimoto, Shuji Ozaki, Shinsuke Kido, Daisuke Inoue, Toshio Matsumoto
Journal: Blood
Blood (2005) 106 (9): 3160–3165.
https://doi.org/10.1182/blood-2004-12-4940
Published: 2005
Journal Articles

Myeloma Cells Suppress Osteoblast Differentiation by Secreting a Soluble Wnt Inhibitor, sFRP-2.

Takashi Oshima, MD, Masahiro Abe, MD, Jin Asano, MD, Tomoko Hara, MD, Kenichi Kitazoe, MD, Etsuko Sekimoto, MD, Yoichi Tanaka, MD, Hironobu Shibata, MD, Toshihiro Hashimoto, MD, Shuji Ozaki, MD, Shinsuke Kido, MD, Daisuke Inoue, MD, Toshio Matsumoto, MD
Journal: Blood
Blood (2004) 104 (11): 2356.
https://doi.org/10.1182/blood.V104.11.2356.2356
Published: 2004
Journal Articles

Myeloma Cells Block Runx2/Cbfa1 Activity in Human Bone Marrow Osteoblast Progenitors and Inhibit Osteoblast Formation and Differentiation.

Nicola Giuliani, MD, PhD, Simona Colla, PhD, Francesca Morandi, PhD, Sabrina Bonomini, PhD, Vittorio Rizzoli, MD, PhD
Journal: Blood
Blood (2004) 104 (11): 632.
https://doi.org/10.1182/blood.V104.11.632.632
Published: 2004