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Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD

Blood (2019) 134 (Supplement_1): 535.

https://doi.org/10.1182/blood-2019-128213

Published: 2019

Journal Articles

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2

Carmelo Carmona-Rivera, Sami S. Khaznadar, Kyawt W. Shwin, Jorge A. Irizarry-Caro, Liam J. O’Neil, Yudong Liu, Kenneth A. Jacobson, Amanda K. Ombrello, Deborah L. Stone, Wanxia L. Tsai, Daniel L. Kastner, Ivona Aksentijevich, Mariana J. Kaplan, Peter C. Grayson

Blood (2019) 134 (4): 395–406.

https://doi.org/10.1182/blood.2018892752

Published: 2019

Includes: Supplemental data

Journal Articles

Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Blood (2018) 132 (Supplement 1): 3842.

https://doi.org/10.1182/blood-2018-99-116015

Published: 2018

Journal Articles

Adenosine Regulation of cAMP through Phosphodiesterases

Bunyan Teng, PhD, Daniel N Darlington, PhD, Andrew P Cap, MD PhD

Blood (2018) 132 (Supplement 1): 2424.

https://doi.org/10.1182/blood-2018-99-114929

Published: 2018

Journal Articles

Carfilzomib Versus Bortezomib in Combination with Cyclophosphamide and Dexamethasone for Treatment of First Relapse or Primary Refractory Multiple Myeloma (MM): Outcomes Based on Genetic Risk and Long Term Follow up of the Phase 2 Muk Five Study

Kwee Yong, MD PhD, Samantha Hinsley, MSc, BSc, Debbie Sherratt, Jessica Kendall, BSc, MSc, Sarah R Brown, PhD MSc, BSc, Louise Flanagan, PhD, Catherine Williams, Jamie Cavenagh, MD PhD, Martin Kaiser, MD, Neil K Rabin, MD, Karthik Ramasamy, MD PhD, Mamta Garg, Holger W. Auner, MD PhD, Stephen F. Hawkins, MBChB, MRCP, Ceri Bygrave, MD FRCPath, MPhil, Ruth M De Tute, BSc,MSc, Gareth Morgan, MD, Faith E. Davies, MD, Roger G. Owen

Blood (2018) 132 (Supplement 1): 306.

https://doi.org/10.1182/blood-2018-99-116624

Published: 2018

Journal Articles

Long-Term Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Polycythemia Vera — Final Phase I/II Peginvera Study Results

Blood (2018) 132 (Supplement 1): 3030.

https://doi.org/10.1182/blood-2018-99-118584

Published: 2018

Journal Articles

Carfilzomib, Cyclophosphamide and Dexamethasone (KCD) Versus Bortezomib, Cyclophosphamide and Dexamethasone (VCD) for Treatment of First Relapse or Primary Refractory Multiple Myeloma (MM): First Final Analysis of the Phase 2 Muk Five Study

Kwee Yong, PhD, Samantha Hinsley, Holger W. Auner, MD PhD, Debbie Sherratt, Ruth Mary De Tute, BSc,MSc, Sarah Brown, Louise Flanagan, Cathy Williams, Jamie Cavenagh, Martin F Kaiser, MD, Neil Rabin, Karthik Ramasamy, Mamta Garg, MD, Stephen F. Hawkins, MBChB, MRCP, Ceri Bygrave, MD FRCPath, MPhil, Gareth J. Morgan, MD PhD, Faith E. Davies, MD, Roger G Owen, MD

Blood (2017) 130 (Supplement 1): 835.

https://doi.org/10.1182/blood.V130.Suppl_1.835.835

Published: 2017

Journal Articles

Evaluation of the Effectiveness and Safety of Pixantrone for the Treatment of Multiply Relapsed or Refractory Aggressive Non Hodgkin B-Cell Lymphoma in an Ongoing International Registry

Pier Luigi Zinzani, MD PhD, Belén Navarro, MD, Juan-Manuel Sancho, MD PhD, Begoña Soler, MD, Silvina Grasso Cicala, PhD, Lorena Yapur, MD, Mario Spione, PharmD, MSc

Blood (2017) 130 (Supplement 1): 5228.

https://doi.org/10.1182/blood.V130.Suppl_1.5228.5228

Published: 2017

Journal Articles

Mutational Concordance from Diagnosis and Relapse in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Katherine Tarlock, MD, Todd M Cooper, DO, Todd A. Alonzo, PhD, Robert Gerbing, BS, Jessica Pollard, MD, Richard Aplenc, MD PhD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD

Blood (2016) 128 (22): 2846.

https://doi.org/10.1182/blood.V128.22.2846.2846

Published: 2016

Journal Articles

Carfilzomib, Cyclophosphamide and Dexamethasone Is Well Tolerated in Patients with Relapsed/Refractory Multiple Myeloma Who Have Received One Prior Regimen

Kwee L Yong, MBChB, PhD, Sarah Brown, Samantha Hinsley, Louise Flanagan, Neil Rabin, MB,BS, PhD, Karthik Ramasamy, Jamie Cavenagh, Roger G Owen, Martin F Kaiser, MD, Eric Low, Catherine Williams

Blood (2015) 126 (23): 1840.

https://doi.org/10.1182/blood.V126.23.1840.1840

Published: 2015

Journal Articles

Targeting Replicative Stress to Treat Hematological Disorders

Francesca Cottini, MD, Giovanni Tonon, MD PhD, Teru Hideshima, MD, PhD, Paul G. Richardson, MD, Kenneth C Anderson

Blood (2015) 126 (23): 2419.

https://doi.org/10.1182/blood.V126.23.2419.2419

Published: 2015

Journal Articles

ATR Inhibition Exacerbates Replication Stress in TP53 or ATM Deficient CLL Cells and Enhances Sensitivity to Chemotherapy and Targeted Therapy

Marwan Kwok, MB ChB, MRCP, Nicholas Davies, PhD, Angelo Agathanggelou, PhD, Edward Smith, BSc, Eva Petermann, PhD, Eliot Yates, BMedSc, Jeffrey Brown, PhD, Alan Lau, PhD, Tatjana Stankovic, MD PhD

Blood (2014) 124 (21): 3340.

https://doi.org/10.1182/blood.V124.21.3340.3340

Published: 2014

Journal Articles

Synthetic Lethal Approaches to Exploit Replicative Stress in Aggressive Myeloma

Francesca Cottini, Teru Hideshima, MDPhD, Rikio Suzuki, MDPhD, Paul G. Richardson, Kenneth C. Anderson, MD, Giovanni Tonon, MDPhD

Blood (2014) 124 (21): 173.

https://doi.org/10.1182/blood.V124.21.173.173

Published: 2014

Journal Articles

The Tumor Suppressor APC/C Cdh1 and Its Role In Replication Stress and The Origin Of Genomic Instability

Julika Krohs, Dominik Schnerch, MD, Marie Follo, Julia Felthaus, Monika Engelhardt, MD, Ralph M. Waesch, MD

Blood (2013) 122 (21): 2489.

https://doi.org/10.1182/blood.V122.21.2489.2489

Published: 2013

Journal Articles

Interaction of HTLV-1 Tax with minichromosome maintenance proteins accelerates the replication timing program

Mathieu Boxus, Jean-Claude Twizere, Sébastien Legros, Richard Kettmann, Luc Willems

Blood (2012) 119 (1): 151–160.

https://doi.org/10.1182/blood-2011-05-356790

Published: 2012

Includes: Supplemental data

Journal Articles

A Novel Function of MLL in the S Phase Checkpoint: MLL Is Phosphorylated by ATR Upon DNA Damage, Which Blocks Its Degradation by the SCF skp2 Proteasome, Leading to Its Accumulation That Directly Inhibits DNA Replication.

Han Liu, Shugaku Takeda, Rakesh Kumar, Todd Westergard, Tej Pandita, Emily Cheng, MD, PhD, James J.-D. Hsieh, MD, PhD

Blood (2009) 114 (22): 450.

https://doi.org/10.1182/blood.V114.22.450.450

Published: 2009

Journal Articles

Identification of Genes Cooperating with Mpl Signaling Using Retroviral Insertional Mutagenesis.

Boguslaw A. Kwiatkowski, Ph.D., Robert E. Richard, MD, PhD

Blood (2009) 114 (22): 4558.

https://doi.org/10.1182/blood.V114.22.4558.4558

Published: 2009

Journal Articles

The Identification of Genes Cooperating with Mpl Signaling Using Insertional Mutagenesis

Boguslaw A. Kwiatkowski, ZhaoMing Dong, Robert E. Richard, MD, PhD

Blood (2008) 112 (11): 3860.

https://doi.org/10.1182/blood.V112.11.3860.3860

Published: 2008

Journal Articles

Integration of DNA Copy Number and Gene Expression Alterations Reveal Novel Insights into the Molecular Pathogenesis and Prognosis of Multiple Myeloma

Yiming Zhou, PhD, Bart Barlogie, MD, PhD, Damir Herman, PhD, Owen Stephens, PhD, Erming Tian, PhD, David Williams, PhD, Marie-astrid Cartron, PhD, Frits van Rhee, MD, PhD, Mauricio Pineda-Roman, MD, PhD, Yazan Alsayed, MD, PhD, Elias Anaissie, MD, PhD, Jeffrey Sawyer, Ph.D., John D. Shaughnessy, Jr., PhD

Blood (2008) 112 (11): 250.

https://doi.org/10.1182/blood.V112.11.250.250

Published: 2008

Journal Articles

Biological Significance and Profile of Length Heteroplasmy in the Hypervariable Segments of the Human Mitochondrial DNA Control Regions from Blood Cells.

Myung-Geun Shin, M.D., Hyeoung-Joon Kim, M.D., Hye-Ran Kim, Hee-Nam Kim, Il-Kwon Lee, Hoon Kook, M.D., Duck Cho, M.D., Jong-Hee Shin, M.D., Soon-Pal Suh, M.D., Dong-Wook Ryang, M.D.

Blood (2004) 104 (11): 3815.

https://doi.org/10.1182/blood.V104.11.3815.3815

Published: 2004

NARROW

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Deficiency of adenosine deaminase 2 triggers adenosine-mediated NETosis and TNF production in patients with DADA2

Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms

Adenosine Regulation of cAMP through Phosphodiesterases

Carfilzomib Versus Bortezomib in Combination with Cyclophosphamide and Dexamethasone for Treatment of First Relapse or Primary Refractory Multiple Myeloma (MM): Outcomes Based on Genetic Risk and Long Term Follow up of the Phase 2 Muk Five Study

Long-Term Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Polycythemia Vera — Final Phase I/II Peginvera Study Results

Carfilzomib, Cyclophosphamide and Dexamethasone (KCD) Versus Bortezomib, Cyclophosphamide and Dexamethasone (VCD) for Treatment of First Relapse or Primary Refractory Multiple Myeloma (MM): First Final Analysis of the Phase 2 Muk Five Study

Evaluation of the Effectiveness and Safety of Pixantrone for the Treatment of Multiply Relapsed or Refractory Aggressive Non Hodgkin B-Cell Lymphoma in an Ongoing International Registry

Mutational Concordance from Diagnosis and Relapse in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Carfilzomib, Cyclophosphamide and Dexamethasone Is Well Tolerated in Patients with Relapsed/Refractory Multiple Myeloma Who Have Received One Prior Regimen

Targeting Replicative Stress to Treat Hematological Disorders

ATR Inhibition Exacerbates Replication Stress in TP53 or ATM Deficient CLL Cells and Enhances Sensitivity to Chemotherapy and Targeted Therapy

Synthetic Lethal Approaches to Exploit Replicative Stress in Aggressive Myeloma

The Tumor Suppressor APC/C Cdh1 and Its Role In Replication Stress and The Origin Of Genomic Instability

Interaction of HTLV-1 Tax with minichromosome maintenance proteins accelerates the replication timing program

A Novel Function of MLL in the S Phase Checkpoint: MLL Is Phosphorylated by ATR Upon DNA Damage, Which Blocks Its Degradation by the SCF skp2 Proteasome, Leading to Its Accumulation That Directly Inhibits DNA Replication.

Identification of Genes Cooperating with Mpl Signaling Using Retroviral Insertional Mutagenesis.

The Identification of Genes Cooperating with Mpl Signaling Using Insertional Mutagenesis

Integration of DNA Copy Number and Gene Expression Alterations Reveal Novel Insights into the Molecular Pathogenesis and Prognosis of Multiple Myeloma

Biological Significance and Profile of Length Heteroplasmy in the Hypervariable Segments of the Human Mitochondrial DNA Control Regions from Blood Cells.

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American Society of Hematology

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American Society of Hematology

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