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Journal Articles

CD162 Is a Key E-Selectin Receptor Promoting Acute Myeloid Leukemia Chemo-Resistance in the Bone Marrow Niche

Johanna D Erbani, Joshua Tay, PhD, Valerie Barbier, Masters, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Ingrid G Winkler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 907.
https://doi.org/10.1182/blood-2019-132233
Published: 2019
Journal Articles

CD93-Signaling Regulates Self-Renewal and Proliferation of Chronic Myeloid Leukemia Stem Cells in Mice and Humans and Might be a Promising Target for Treatment

Carsten Riether, PhD, Ramin Radpour, PhD, Chantal L. Bachmann, MSc, Christian M Schürch, MD PhD, Miroslav Arambasic, PhD, Gabriela M Baerlocher, MD, Adrian F Ochsenbein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 187.
https://doi.org/10.1182/blood-2019-127864
Published: 2019
Journal Articles

Syndecan-1 Is Critical in ARF6-Dependent Macropinocytosis Driven By KRAS Mutation in the Pathophysiology of Multiple Myeloma

Tengteng Yu, MD PhD, Liang Lin, PhD, Kenneth Wen, Lijie Xing, MD, Jiye Liu, PhD, Shih-Feng Cho, MD PhD, Phillip Hsieh, Ola Rizq, MD PhD, Yuyin Li, PhD, Liang Yu, Xiang Wu, Eugenio Morelli, MD, Yan Xu, MD, Gang An, MD, Nikhil C. Munshi, MD, Lugui Qiu, MD PhD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4371.
https://doi.org/10.1182/blood-2019-127454
Published: 2019
Journal Articles

Synergistic Activity of Belantamab Mafodotin (anti-BCMA immuno-conjugate) with PF-03084014 (gamma-secretase inhibitor) in Bcma-Expressing Cancer Cell Lines

Stephen Eastman, BS, MS, Christopher Shelton, Ira Gupta, Julie Krueger, Christina Blackwell, Paul M Bojczuk
Journal: Blood
Blood (2019) 134 (Supplement_1): 4401.
https://doi.org/10.1182/blood-2019-123705
Published: 2019
Journal Articles

Quantitative Proteomics in Diffuse Large B-Cell Lymphoma Patients Reveal Novel Overexpressed Proteins and Potentially Druggable Targets in the ABC Subtype

Susanne Bram Ednersson, MD, Mimmie Stern, MD, Henrik Fagman, Gunilla Enblad, Ulf-Henrik Mellqvist, MD PhD, Herman Nilsson-Ehle, MD PhD, Sverker Hasselblom, Per-Ola Andersson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3967.
https://doi.org/10.1182/blood-2019-126387
Published: 2019
Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3972.
https://doi.org/10.1182/blood-2019-121847
Published: 2019
Journal Articles

B-Cell Maturation Antigen (BCMA) in Systemic Light-Chain Amyloidosis (AL): Association with Disease Activity and Its Modulation with Gamma-Secretase Inhibition

Amandeep Godara, MD, Ping Zhou, MD PhD, Benjamin Rosenthal, BS, Adin Kugelmass, BSc, Denis Toskic, BS, Teresa Fogaren, NP, Cindy Varga, MD BSc, Raymond L Comenzo, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4409.
https://doi.org/10.1182/blood-2019-126988
Published: 2019
Journal Articles

Interactions between Donor Activating Killer Immunoglobulin-like Receptors (KIRs) and Somatic Mutations and Their Association with Outcomes after Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia (AML)

Sanghee Hong, MD, Lisa Rybicki, MS, Aiwen Zhang, PhD, Dawn Thomas, Cassandra M Kerr, MS, Donna Corrigan, Arden Emrick, Hetty E. Carraway, MD MBA, Aziz Nazha, MD, Sudipto Mukherjee, MD PhD MPH, Anjali S. Advani, MD, Matt Kalaycio, MD, Brian J. Bolwell, MD, Rabi Hanna, MD, Aaron T. Gerds, MD MS, Brad Pohlman, MD, Betty K. Hamilton, MD, Mikkael A. Sekeres, MD MS, Navneet S. Majhail, MD MS, Jaroslaw P. Maciejewski, MD PhD, Medhat Askar, MD PhD, Ronald Sobecks, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4599.
https://doi.org/10.1182/blood-2019-131011
Published: 2019
Journal Articles

Clinical Significance of KIR Genotype in Patients with Methotrexate-Associated Lymphoproliferative Disorders

Norina Tanaka, MD PhD, Aya Watanabe, MD, Suguru Honda, MD, Mitsuko Kobayashi, Yan-Hua Wang, MD, Yuki Iizuka, MD, Michiko Ryuzaki, MD, Midori Ishiyama, MD PhD, Akihito Shinohara, MD PhD, Hiroshi Kazama, MD PhD, Shotaro Hagiwara, MD PhD, Kentaro Yoshinaga, MD PhD, Katsunori Ikari, MD PhD, Masayuki Shiseki, MD PhD, Masayoshi Harigai, MD PhD, Junji Tanaka, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5219.
https://doi.org/10.1182/blood-2019-127836
Published: 2019
Journal Articles

Paracrine Bone Morphogenetic Protein Signaling in Iron Homeostasis

Jodie L. Babitt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-26.
https://doi.org/10.1182/blood-2019-121069
Published: 2019
Journal Articles

Signaling Input from Divergent Pathways Subverts Malignant B-Cell Transformation

Lai N Chan, PhD, Mark A. Murakami, MDMA,MMSc, Rebecca Caesar, Christian Hurtz, PhD, Kohei Kume, PhD, Teresa Sadras, PhD, Seyedmehdi Shojaee, PhD, Petri Pölönen, MSc, Amol Ugale, PhD, Jaewoong Lee, PhD, Kadriye Nehir Cosgun, PhD, Huimin Geng, PhD, Merja Heinäniemi, PhD, Olli Lohi, MD PhD, Arun P. Wiita, MD PhD, Shai Izraeli, MD, David M Weinstock, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3944.
https://doi.org/10.1182/blood-2019-130774
Published: 2019
Journal Articles

Targeting B-Cell Maturation Antigen (BCMA) with CC-93269, a 2+1 T Cell Engager, Elicits Significant Apoptosis in Diffuse Large B-Cell Lymphoma Preclinical Models

Patrick R. Hagner, PhD, Michelle Waldman, MS, Falon D. Gray, DVM, DACVP, Renee Yura, PhD, Sarah Hersey, MS, MBA, Henry Chan, PhD, Mingjun Zhang, PhD, Isaac Boss, Anita K Gandhi
Journal: Blood
Blood (2019) 134 (Supplement_1): 1580.
https://doi.org/10.1182/blood-2019-126115
Published: 2019
Journal Articles

Dreamm-5: Platform Trial Evaluating Belantamab Mafodotin (a BCMA-directed Immuno-conjugate) in Combination with Novel Agents in Relapsed or Refractory Multiple Myeloma (RRMM)

Paul G. Richardson, MD, Swethajit Biswas, Beata Holkova, Nicola Jackson, Thelma Netherway, Weichao Bao, Geraldine Ferron-Brady, Anne Yeakey, Chris Shelton, Rocio Montes De Oca, PhD, Chris Ahlers, Sonia Franco, Marc Ballas, Elaine Paul, Katarina Luptakova, Ira Gupta, Joanna Opalinska
Journal: Blood
Blood (2019) 134 (Supplement_1): 1857.
https://doi.org/10.1182/blood-2019-129879
Published: 2019
Journal Articles

Integrated Single Cell Transcriptomics Defines an Engineered Niche Supporting Hematopoietic Stem Cell Development Ex Vivo

Brandon Hadland, MD PhD, Barbara Varnum-Finney, PhD, Stacey Dozono, Tessa Dignum, Cynthia Nourigat-Mckay, Dana Jackson, Shahin Rafii, MD, Cole Trapnell, PhD, Irwin D. Bernstein, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3699.
https://doi.org/10.1182/blood-2019-126109
Published: 2019
Journal Articles

Hematopoietic Phf6 Deletion in Mice Causes HSC Depletion and Expansion of Myeloid Progenitors

Roman Verner, Gabrielle Ochoco, Patrick Somers, Cristian Taborda, Vikram R Paralkar, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3829.
https://doi.org/10.1182/blood-2018-99-120041
Published: 2018
Journal Articles

A MAFB Associated Regulatory Network Distinguishes CMML from Other MDS/MPN Overlap Entities

Wencke Walter, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach, MD, Manja Meggendorfer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3890.
https://doi.org/10.1182/blood-2018-99-115838
Published: 2018
Journal Articles

Osteoclast Stimulatory Transmembrane Protein ( OCSTAMP ) mRNA Levels and Clinical Variables in Persons with Plasma Cell Myeloma

Ya-Lan Zhou, MD, Jin Lu, Robert Peter Gale, Shen-Miao Yang, Li-Xin Wu, Jin-Lan Li, Ya-Zhen Qin, Yan-Rong Liu, Hao Jiang, Qian Jiang, MD, Xiaohui Zhang, MD, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, Guorui Ruan
Journal: Blood
Blood (2018) 132 (Supplement 1): 5264.
https://doi.org/10.1182/blood-2018-99-116883
Published: 2018
Journal Articles

Expression of Myeloma Cell and Soluble B-Cell Maturation Antigen (BCMA) in Relapsed and Refractory Multiple Myeloma Patients Treated with GSK2857916 in BMA117159

E.J. Dettman, PhD BS, Fabio Rigat, PhD, Josh Albert, BS, Ruth Barnard, PhD, Mary Birchler, BS, Yan Deghenhardt, PhD, Stephen DeWall, PhD, Boyenoh Gaye, MS, Zangdong He, PhD, Veronica Liu, MS, Joanna Opalinska
Journal: Blood
Blood (2018) 132 (Supplement 1): 1977.
https://doi.org/10.1182/blood-2018-99-115200
Published: 2018
Journal Articles

Myeloma Patient-Derived Bone Marrow Serum Negatively Regulates Natural Killer Cell Activity

Tarun K. Garg, PhD, Katie Stone, BS, Hongwei Wang, MS, Antje Hoering, PhD, Brian A Walker, PhD, Maurizio Zangari, MD, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Faith E. Davies, MD, Gareth Morgan, MD, Frits van Rhee, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4468.
https://doi.org/10.1182/blood-2018-99-119692
Published: 2018
Journal Articles

Active Immune Thrombocytopenia (ITP) Disease Is Characterised By a Reduced Treg:CD8 Effector T Cell Ratio Which Is Modulated By Thrombopoietin-Receptor Agonists (TPO-RA)

Anwar A. Sayed, MBBS, MSc, Amna Malik, PhD, Ahmad Khoder, MD PhD MRCP, George Adams, MBChB, Nichola Cooper, MRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 2430.
https://doi.org/10.1182/blood-2018-99-113563
Published: 2018