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Journal Articles

CRISPR Dropout Screens Identify DHODH, PIK3C3 , and Crkl as Potential Therapeutic Targets in Acute Myeloid Leukemia

Gregory Takacs, BS, Yujia Zhou, BS,BA, David J. King, BS, Amy Meacham, MS, Loguinov Alex, PhD, Abderrahmane Tagmount, PhD, Amin Sobh, PhD, Max Russo, BS, Chris D Vulpe, MD PhD, Christopher R. Cogle, MD

Blood (2019) 134 (Supplement_1): 1452.

https://doi.org/10.1182/blood-2019-128180

Published: 2019

Journal Articles

MCL-1 Inhibitor-Induced Killing of Multiple Myeloma Is Modulated By the Relative Level of Expression of Pro-Survival Members of the BCL-2 Family and the Proto-Oncogene MYC

Andrew Spencer, DM, Tiffany Khong, BSc, PhD, Maoshan Chenn, PhD

Blood (2019) 134 (Supplement_1): 1825.

https://doi.org/10.1182/blood-2019-127843

Published: 2019

Journal Articles

A Distinct Oncofetal B-Cell Transcriptional Program Is Activated in Infant Acute Myeloid Leukemia and Reveals Novel Therapeutic Strategies

Hamid Bolouri, PhD, Benjamin K. Johnson, PhD, Rhonda E. Ries, MA, Laura Pardo, Tiffany A. Hylkema, BS, Wanding Zhou, PhD, Jenny L. Smith, MSc, MD, Amanda R. Leonti, MS, Allison Kaeding, MD, Michael R. Loken, PhD, Jason E. Farrar, MD, Soheil Meshinchi, MD PhD, Timothy Junius Triche, Jr., PhD

Blood (2019) 134 (Supplement_1): 3768.

https://doi.org/10.1182/blood-2019-123487

Published: 2019

Journal Articles

S-Phase Progression of North American ATLL Cells Is Critically Regulated By the Proto-Oncogene BCL6 and Targetable By PARP Inhibition

B. Hilda Ye, PhD, Elaine Chung, PhD, Kith Pradhan, PhD, Ana Acuna-Villaorduna, MD, Yanhua Wang, MD PhD, Aditi Shastri, MD, Advaitha Madireddy, PhD, Amit Verma, MBBS, R.Alejandro Sica, MD, Murali Janakiram, MD MS

Blood (2019) 134 (Supplement_1): 3779.

https://doi.org/10.1182/blood-2019-131364

Published: 2019

Journal Articles

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Simone Ragaini, MD, Sarah Wagner, BSc MSc, Giovanni Marconi, Sarah Parisi, MD PhD, Chiara Sartor, MD, Jacopo Nanni, MD, Gianluca Cristiano, Annalisa Talami, MD, Matteo Olivi, MD, Darina Ocadlikova, PhD, Marilena Ciciarello, PhD, Giulia Corradi, PhD, Emanuela Ottaviani, Cristina Papayannidis, Stefania Paolini, MD PhD, Jayakumar Vadakekolathu, PhD, Michele Cavo, Sergio Rutella, MD PhD FRCPath, Antonio Curti, MD PhD

Blood (2019) 134 (Supplement_1): 5193.

https://doi.org/10.1182/blood-2019-128348

Published: 2019

Journal Articles

Title: SNP Microarray Reveals Predicted Outcomes of a Novel High Risk AML Subgroup with ERG Amplification

Sandra Mazzoni, BS,DO,MT(ASCP), Brian T. Hess, MD, Cynthia Schandl, MD PhD, Iya Znoyko, PhD, Georges Nahhas, Dongjun Chung, Assistant Professor, PhD, Yanna Ding, MD PhD, Daynna Wolff, PhD FACMG

Blood (2019) 134 (Supplement_1): 2737.

https://doi.org/10.1182/blood-2019-121408

Published: 2019

Journal Articles

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

Sebastian Vosberg, Paul Kerbs, MSc, Vindi Jurinovic, MSc, Klaus H. Metzeler, MD, Susanne Amler, PhD, Cristina Sauerland, Dennis Görlich, PhD, Wolfgang E. Berdel, MD, Jan Braess, MD, Wolfgang Hiddemann, MD PhD, Karsten Spiekermann, MD, Tobias Herold, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 2715.

https://doi.org/10.1182/blood-2019-130047

Published: 2019

Journal Articles

IGFBP7 As a Potential Therapeutic Target for AML

Yina Niu, PhD, Shuiyan Wu, MD, Shaoyan Hu, MD PhD

Blood (2018) 132 (Supplement 1): 5134.

https://doi.org/10.1182/blood-2018-99-119528

Published: 2018

Journal Articles

Mice with a Unique Mutator Phenotype Allow Detection of Lymphoid Leukemia Tumor Suppressor Genes

Mianmian Yin, PhD, Timour Baslan, PhD, Amy Freeland, PhD, Toshihiro Matsukawa, PhD, Steven C. Pruitt, PhD, Peter D. Aplan, MD

Blood (2018) 132 (Supplement 1): 1332.

https://doi.org/10.1182/blood-2018-99-115176

Published: 2018

Journal Articles

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

Vibe Skov, PhD, Katrine LM Schmidt, Kasper Mønsted Pedersen, MD, Bettina Hansen, Tobias Wirenfeldt Klausen, M.S., Torben A Kruse, Mads Thomassen, PhD, Lasse Kjær, PhD, Christina Ellervik, Associate Professor, MD PhD, Morten Holmstrøm, MD, Bjørn Nexø, Hans Carl Hasselbalch, Professor, dr.MD, Magdalena J Laska

Blood (2018) 132 (Supplement 1): 5488.

https://doi.org/10.1182/blood-2018-99-118080

Published: 2018

Journal Articles

Fusion Transcripts without Corresponding Cytogenetic Abnormalities in Acute Myeloid Leukemia: Implications for AML Pathogenesis

Irene J. Locher, Wibowo Arindrarto, M.Sc., Daniel M. Borràs, M.Sc., M. Willy Honders, ing., Rick H. de Leeuw, ing., Wilma G.M. Kroes, PhD, Peter de Knijff, PhD, Cornelis A.M. van Bergen, PhD, Peter A.C. 't Hoen, PhD, Szymon M. Kielbasa, PhD, Jeroen F.J. Laros, PhD, Marieke Griffioen, PhD, Hendrik Veelken, MD PhD

Blood (2017) 130 (Supplement 1): 2703.

https://doi.org/10.1182/blood.V130.Suppl_1.2703.2703

Published: 2017

Journal Articles

The Proto-Oncogene Mer Is a Novel Therapeutic Target in Mantle Cell Lymphoma

Cunzhen Shi, Xiaogan Wang, MD, Ning Ding, MD, Lingyan Ping, Yuqin Song, MD, Jun Zhu, BS

Blood (2017) 130 (Supplement 1): 5138.

https://doi.org/10.1182/blood.V130.Suppl_1.5138.5138

Published: 2017

Journal Articles

Comprehensive Genomic Profiling (CGP) Identifies Novel BCL6 Rearrangements in Diverse Subtypes of Non-Hodgkin Lymphoma (NHL) As Well As Known Rearrangements Not Detected Using Standard of Care (SOC) Assays

Jo-Anne Vergilio, MD, Laurie M Gay, PhD, Lei Zhong, PhD, Mark Rosenzweig, PhD, Yakov Chudnovsky, PhD, Jie He, PhD, Michelle Nahas, PhD, Siraj M Ali, MD PhD, Sugganth Daniel, MD, Shakti Ramkissoon, MD PhD, James Suh, MD, Julia A Elvin, MD PhD, Tariq I Mughal, MD FRCP, Philip J Stephens, PhD, Vincent A Miller, MD, Rachel Erlich, PhD, Jeffrey S Ross, MD, Eric A Severson, MD PhD MMSc, Samantha Morley, PhD

Blood (2017) 130 (Supplement 1): 417.

https://doi.org/10.1182/blood.V130.Suppl_1.417.417

Published: 2017

Journal Articles

Reciprocal Regulation of BCL6 and MLL Expression As a Vulnerability in MLL -Rearranged Acute Lymphoblastic Leukemia

Lai N Chan, Christian Hurtz, PhD, Huimin Geng, PhD, Cheryl L. Willman, MD, William L. Carroll, MD, Scott Armstrong, MD PhD, Thomas Arthur Milne, PhD BSc, MSc, Markus Muschen, MD

Blood (2017) 130 (Supplement 1): 1210.

https://doi.org/10.1182/blood.V130.Suppl_1.1210.1210

Published: 2017

Journal Articles

Oncogenic Feedback Activation Between BCL6 and MLL Promotes Malignant Transformation in MLL -RearrangedAcute Lymphoblastic Leukemia

Christian Hurtz, PhD, Lai N Chan, PhD, Erica Ballabio, MD, Cheryl L. Willman, William L. Carroll, MD, Scott A. Armstrong, MD PhD, Patricia Ernst, PhD, Ari Melnick, MD, Thomas Milne, PhD, Markus Müschen, MD PhD

Blood (2016) 128 (22): 907.

https://doi.org/10.1182/blood.V128.22.907.907

Published: 2016

Journal Articles

Foamy Virus Backbone Has Insulator Properties Which Remarkably Reduce Its Genotoxicity Potential

Michael Goodman, MD, Paritha Arumugam, PhD, Devin Pillis, MS, Danielle Lynn, MS, Johannes C.M. Van der Loo, PhD, Mehdi Keddache, PhD, Thomas R. Bauer, Jr., PhD, Dennis D. Hickstein, MD, David W Russell, MD PhD, Punam Malik, MD

Blood (2016) 128 (22): 1002.

https://doi.org/10.1182/blood.V128.22.1002.1002

Published: 2016

Journal Articles

BCL6 Is Critical to Overcome Oncogene-Induced Senescence in RAS-Mediated B Cell Transformation

Lai N Chan, PhD, Christian Hurtz, PhD, Gang Xiao, PhD, Seyedmehdi Shojaee, PhD, Rebecca Caeser, Huimin Geng, PhD, Ari Melnick, MD, Markus Müschen, MD PhD

Blood (2016) 128 (22): 438.

https://doi.org/10.1182/blood.V128.22.438.438

Published: 2016

Journal Articles

Blood ’s 70th anniversary: 1988-1992

Arthur W. Nienhuis

Blood (2016) 127 (9): 1075–1076.

https://doi.org/10.1182/blood-2015-10-638668

Published: 2016

Journal Articles

Identification of CKMT1B As a New Target in EVI1-Positive AML

Alexandre Puissant, PhD, Nina Fenouille, PhD, Christopher F. Bassil, BA, Issam Ben-Sahra, PhD, Gabriela Alexe, PhD, Lina Benajiba, Azucena Ramos, Yana Pikman, MD, Michael R. Burgess, MD PhD, Ilene Galinsky, ANP, Daniel J. DeAngelo, MD PhD, Richard M. Stone, MD, Kevin Shannon, MD, Michael T. Hemann, PhD, Kimberly Stegmaier, MD

Blood (2015) 126 (23): 3674.

https://doi.org/10.1182/blood.V126.23.3674.3674

Published: 2015

Journal Articles

Definitive Erythro-Myeloid Progenitors (EMPs) Emerge in the Myb -/- Embryo and Retain the Capacity to Differentiate into Macrophages

Jenna M. Frame, PhD, Katherine H. Fegan, MS, Seana C. Catherman, BS, Joanna Tober, PhD, Anne D. Koniski, MS, Kathleen E McGrath, PhD, James Palis, MD

Blood (2015) 126 (23): 2372.

https://doi.org/10.1182/blood.V126.23.2372.2372

Published: 2015

NARROW

CRISPR Dropout Screens Identify DHODH, PIK3C3 , and Crkl as Potential Therapeutic Targets in Acute Myeloid Leukemia

MCL-1 Inhibitor-Induced Killing of Multiple Myeloma Is Modulated By the Relative Level of Expression of Pro-Survival Members of the BCL-2 Family and the Proto-Oncogene MYC

A Distinct Oncofetal B-Cell Transcriptional Program Is Activated in Infant Acute Myeloid Leukemia and Reveals Novel Therapeutic Strategies

S-Phase Progression of North American ATLL Cells Is Critically Regulated By the Proto-Oncogene BCL6 and Targetable By PARP Inhibition

An IDO1 -Related 3-Gene Signature Predicts Overall Survival in Intermediate-Risk Acute Myeloid Leukemia

Title: SNP Microarray Reveals Predicted Outcomes of a Novel High Risk AML Subgroup with ERG Amplification

DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome

IGFBP7 As a Potential Therapeutic Target for AML

Mice with a Unique Mutator Phenotype Allow Detection of Lymphoid Leukemia Tumor Suppressor Genes

Genetic Evidence for Involvement of Human Endogenous Retrovirus Herv-Fc1 in the Pathogenesis of MPNs

Fusion Transcripts without Corresponding Cytogenetic Abnormalities in Acute Myeloid Leukemia: Implications for AML Pathogenesis

The Proto-Oncogene Mer Is a Novel Therapeutic Target in Mantle Cell Lymphoma

Comprehensive Genomic Profiling (CGP) Identifies Novel BCL6 Rearrangements in Diverse Subtypes of Non-Hodgkin Lymphoma (NHL) As Well As Known Rearrangements Not Detected Using Standard of Care (SOC) Assays

Reciprocal Regulation of BCL6 and MLL Expression As a Vulnerability in MLL -Rearranged Acute Lymphoblastic Leukemia

Oncogenic Feedback Activation Between BCL6 and MLL Promotes Malignant Transformation in MLL -RearrangedAcute Lymphoblastic Leukemia

Foamy Virus Backbone Has Insulator Properties Which Remarkably Reduce Its Genotoxicity Potential

BCL6 Is Critical to Overcome Oncogene-Induced Senescence in RAS-Mediated B Cell Transformation

Blood ’s 70th anniversary: 1988-1992

Identification of CKMT1B As a New Target in EVI1-Positive AML

Definitive Erythro-Myeloid Progenitors (EMPs) Emerge in the Myb -/- Embryo and Retain the Capacity to Differentiate into Macrophages

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American Society of Hematology

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ASH Publications

American Society of Hematology

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