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Journal Articles

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

Yu Sun, BSc, MSc, PhD, Jayna J Mistry, BSc, Jamie A Moore, BSc, MSc, Charlotte Hellmich, MBBChir, Christopher R Marlein, PhD, Anna Haestier, Cesar A. Gomez, MD PhD FRCPath, Christopher J Morris, PhD, Kristian M Bowles, MBBS, PhD, Stuart A Rushworth, PhD

Blood (2019) 134 (Supplement_1): 689.

https://doi.org/10.1182/blood-2019-128268

Published: 2019

Journal Articles

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

Zhenzhen Zhao, Yi Wu, Junsong Zhou, Fengwu Chen, Aizhen Yang, David W. Essex

Blood (2019) 133 (3): 246–251.

https://doi.org/10.1182/blood-2018-04-844480

Published: 2019

Includes: Supplemental data

Journal Articles

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Jeffrey I. Zwicker, MD, Benjamin L. Schlechter, MD, Jack Davis Stopa, PhD, Howard A. Liebman, MD, Anita Aggarwal, PhDDO, Thomas Caughey, MD, Ken A. Bauer, MD, Nancy Kuemmerle, D.O., Ellice Y. Wong, MD, Ted Wun, MD, Marilyn Mclaughlin, MD, Maneka Puligandla, MS, Donna S Neuberg, ScD, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD

Blood (2018) 132 (Supplement 1): 985.

https://doi.org/10.1182/blood-2018-99-114946

Published: 2018

Journal Articles

Tannic Acid Inhibits Protein Disulfide Isomerase, Platelet Activation and Thrombus Formation

Li Zhu, MD PhD

Blood (2018) 132 (Supplement 1): 2418.

https://doi.org/10.1182/blood-2018-99-114418

Published: 2018

Journal Articles

Rutin Increases Shear-Dependent TGF-β1 Activation By Interacting with Putative PDI Binding Sites: Role of Oxidation in Shear-Dependent TGF-β1 Activation

Landon Haslem, Jasimuddin Ahamed, PhD

Blood (2017) 130 (Supplement 1): 3652.

https://doi.org/10.1182/blood.V130.Suppl_1.3652.3652

Published: 2017

Journal Articles

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Chao Fang, PhD, Anish V. Sharda, MBBS, MPH, Lin Lin, PhD, Robert C. Flaumenhaft, MD PhD, Bruce Furie, MD

Blood (2017) 130 (Supplement 1): 442.

https://doi.org/10.1182/blood.V130.Suppl_1.442.442

Published: 2017

Journal Articles

Protein Disulfide Isomerase Negatively Regulates Platelet Function through Modulation of the Thromboxane A2 Receptor

Noppacharn Uaprasert, MB, BCH, Oskar Eriksson, MD PhD, Robert C. Flaumenhaft, MD PhD

Blood (2017) 130 (Supplement 1): 2297.

https://doi.org/10.1182/blood.V130.Suppl_1.2297.2297

Published: 2017

Journal Articles

Platelet Tissue Factor Activity Is Specifically Induced By Gpib Activation Pathway, Independent of GPVI, α IIb β and Protein Disulfide Isomerase Activities

Olga Panes, BM, BCh, Valeria Matus, PhD, Claudia G Sáez, PhD, Jaime Pereira, MD, Luz María Pozo, BCh, Diego Mezzano, MD

Blood (2017) 130 (Supplement 1): 2305.

https://doi.org/10.1182/blood.V130.Suppl_1.2305.2305

Published: 2017

Journal Articles

The disulfide isomerase ERp72 supports arterial thrombosis in mice

Junsong Zhou, Yi Wu, Fengwu Chen, Lu Wang, Lubica Rauova, Vincent M. Hayes, Mortimer Poncz, Hong Li, Tong Liu, Junling Liu, David W. Essex

Blood (2017) 130 (6): 817–828.

https://doi.org/10.1182/blood-2016-12-755587

Published: 2017

Includes: Supplemental data

Journal Articles

Activation of the Mineralocorticoid Receptor Stimulates Protein Disulfide Isomerase: Role in Sickle Cell Disease

Alexandra Lozano, Christopher Vega, Yaritza Inostroza-Nieves, Lorena Rivera González, Pablo J. López, Jamie Rosado Alicea, Gregory N. Prado, Alicia Rivera, Jose R. Romero

Blood (2016) 128 (22): 1351.

https://doi.org/10.1182/blood.V128.22.1351.1351

Published: 2016

Journal Articles

Targeted Whole Exome Sequencing of 87 Predisposition Genes in 156 Patients from the Oresund Region with Bleeding Disorders

Eva B Leinoe, MD PhD, Eva Zetterberg, MD PhD, Olga Oestrup, Molecular biologist, PhD, Peter Kampmann, MD, Norstrom Eva, MD PhD, Nadine G Andersson, MD PhD, Savvas Kinalis, Data scientist, Klaus Qvortrup, Professor MD PhD, Caroline Maria Rossing, MD PhD

Blood (2016) 128 (22): 361.

https://doi.org/10.1182/blood.V128.22.361.361

Published: 2016

Journal Articles

Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells Towards Cytostatics

Fabian Koczian, Jan Vomacka, Binje Vick, PhD, Britta F Hettich, Uli Kazmaier, Stephan A Sieber, Irmela Jeremias, MD, Angelika M Vollmar, Simone Braig

Blood (2016) 128 (22): 2319.

https://doi.org/10.1182/blood.V128.22.2319.2319

Published: 2016

Journal Articles

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

Jack D Stopa, PhD, Donna S. Neuberg, ScD, Maneka Puligandla, MS, Bruce Furie, MD, Robert C. Flaumenhaft, MD PhD, Jeffrey I. Zwicker, MD

Blood (2016) 128 (22): 2628.

https://doi.org/10.1182/blood.V128.22.2628.2628

Published: 2016

Journal Articles

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

Chao Fang, PhD, Sheryl R. Bowley, PhD, Barbara C. Furie, PhD, Bruce Furie, MD

Blood (2016) 128 (22): 15.

https://doi.org/10.1182/blood.V128.22.15.15

Published: 2016

Journal Articles

von Willebrand factor is dimerized by protein disulfide isomerase

Svenja Lippok, Katra Kolšek, Achim Löf, Dennis Eggert, Willem Vanderlinden, Jochen P. Müller, Gesa König, Tobias Obser, Karoline Röhrs, Sonja Schneppenheim, Ulrich Budde, Carsten Baldauf, Camilo Aponte-Santamaría, Frauke Gräter, Reinhard Schneppenheim, Joachim O. Rädler, Maria A. Brehm

Blood (2016) 127 (9): 1183–1191.

https://doi.org/10.1182/blood-2015-04-641902

Published: 2016

Includes: Multimedia, Supplemental data

Journal Articles

The Second CGHC Motif of Protein Disulfide Isomerase Mediates Thrombosis

Junsong Zhou, BS, Yi Wu, Lu Wang, BS, Lubica Rauova, MD PhD, Vincent M Hayes, BS, Mortimer Poncz, MD, David W Essex, MD

Blood (2015) 126 (23): 1032.

https://doi.org/10.1182/blood.V126.23.1032.1032

Published: 2015

Journal Articles

Platelet Surface PDI Controls the Ligand-Binding Function of Glycoprotein Ibalpha and Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions

Kyungho Kim, PhD, Jing Li, PhD, Robert K Andrews, PhD, Joyce Chiu, PhD, Philip Hogg, PhD, Jaehyung Cho, PhD

Blood (2015) 126 (23): 235.

https://doi.org/10.1182/blood.V126.23.235.235

Published: 2015

Journal Articles

Protein Disulfide Isomerase in Sickle Cell Disease

Daniel Gil de Lamadrid, Yaritza Inostroza-Nieves, Joshua Cazares, Isamar Alicea, Analaura Santiago, Shirley Valentin, Jose R Romero, Alicia Rivera

Blood (2015) 126 (23): 2166.

https://doi.org/10.1182/blood.V126.23.2166.2166

Published: 2015

Journal Articles

Biallelic Mutations in PARP4 Are Linked to a Variant Form of Congenital Dyserythropoietic Anemia

Paola Bianchi, PhD, Elisa Fermo, PhD, Jennifer C Eng, Jacob C Ulirsch, Cristina Vercellati, BSc, Paola Braidotti, MD, Gordon Hildick-Smith, Timothy J Satchwell, PhD, Stephanie Pellegrin, PhD, Alberto Zanella, MD, Wilma Barcellini, MD, Barry H. Paw, MD, PhD, Ashley Mark Toye, PhD, Vijay G Sankaran, MD PhD

Blood (2015) 126 (23): 272.

https://doi.org/10.1182/blood.V126.23.272.272

Published: 2015

Journal Articles

Comparative Proteomic Analysis of Bone Marrow Plasma Cells By Using Mass Spectrometry Based Bottom up Proteomic Strategies

Ayhan Beycan, PhD, Duygu Fatma Ozel Demiralp, Klara Dalva, Meral Beksaç, MD

Blood (2015) 126 (23): 5334.

https://doi.org/10.1182/blood.V126.23.5334.5334

Published: 2015

NARROW

Myeloma Derived Extracellular Vesicles Containing Endoplasmic Reticulum Remodel the Bone Marrow Microenvironment Towards a Pro-Tumoral Senescent Phenotype

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

Targeting Protein Disulfide Isomerase with the Oral Flavonoid Isoquercetin Prevents Venous Thromboembolism in Advanced Cancer: Results of a Multi-Dose, Multi-Center, Phase II Clinical Trial (CATIQ Study)

Tannic Acid Inhibits Protein Disulfide Isomerase, Platelet Activation and Thrombus Formation

Rutin Increases Shear-Dependent TGF-β1 Activation By Interacting with Putative PDI Binding Sites: Role of Oxidation in Shear-Dependent TGF-β1 Activation

Inhibition of Protein Disulfide Isomerase Ameliorates Vaso-Occlusion and Thrombosis in a Mouse Model of Sickle Cell Disease

Protein Disulfide Isomerase Negatively Regulates Platelet Function through Modulation of the Thromboxane A2 Receptor

Platelet Tissue Factor Activity Is Specifically Induced By Gpib Activation Pathway, Independent of GPVI, α IIb β and Protein Disulfide Isomerase Activities

The disulfide isomerase ERp72 supports arterial thrombosis in mice

Activation of the Mineralocorticoid Receptor Stimulates Protein Disulfide Isomerase: Role in Sickle Cell Disease

Targeted Whole Exome Sequencing of 87 Predisposition Genes in 156 Patients from the Oresund Region with Bleeding Disorders

Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells Towards Cytostatics

PDI Inhibition Blocks Thrombin Generation in Humans By Interfering with Platelet Factor V Activation

Extracellular Protein Disulfide Isomerase Regulates Vitronectin during the Initiation of Thrombus Formation

von Willebrand factor is dimerized by protein disulfide isomerase

The Second CGHC Motif of Protein Disulfide Isomerase Mediates Thrombosis

Platelet Surface PDI Controls the Ligand-Binding Function of Glycoprotein Ibalpha and Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions

Protein Disulfide Isomerase in Sickle Cell Disease

Biallelic Mutations in PARP4 Are Linked to a Variant Form of Congenital Dyserythropoietic Anemia

Comparative Proteomic Analysis of Bone Marrow Plasma Cells By Using Mass Spectrometry Based Bottom up Proteomic Strategies

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American Society of Hematology

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American Society of Hematology

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