1-20 of 602
phosphoric monoester hydrolases
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

Zoltan Nagy, Jun Mori, Vanesa-Sindi Ivanova, Alexandra Mazharian, Yotis A. Senis
Journal: Blood
Blood (2020) 135 (18): 1574–1587.
https://doi.org/10.1182/blood.2019002848
Published: 2020
Includes: Supplemental data
Journal Articles

PP2A Activators Enhance Efficacy of FLT3 Inhibitors in FLT3-ITD Acute Myeloid Leukemia Cells through AKT Inactivation-Dependent Pim-1 and c-Myc Proteasomal Degradation

Mario Scarpa, PhD, Prerna Singh, MS, Shivani Kapoor, MS, Jonelle K. Lee, MS, Sandrine Niyongere, MD, Goutham Narla, MD PhD, Danilo Perrotti, MD PhD, Maria R. Baer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1276.
https://doi.org/10.1182/blood-2019-129011
Published: 2019
Journal Articles

PPM1D and DNMT3A Mutations in Myelodysplasia and Clonal Hematopoiesis

Masanori Motomura, Yoshikage Inoue, Yasunobu Nagata, MD PhD, Tetsuichi Yoshizato, MD PhD, Constance Baer, PhD, Yukihide Momozawa, Niroshan Nadarajah, Yasuhito Nannya, MD PhD, Kenichi Yoshida, MD PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Yoshiko Atsuta, MD PhD, Yuka Iijima-Yamashita, Yuichi Shiraishi, PhD, Makoto Onizuka, MD PhD, Kenichi Chiba, PhD, Hiroko Tanaka, BA, Hidehiro Itonaga, MD PhD, Yasushi Miyazaki, MD PhD, Keizo Horibe, MD PhD, Masashi Sanada, MD, Yoichiro Kamatani, Michiaki Kubo, MD PhD, Satoru Miyano, PhD, Torsten Haferlach, MD, Seishi Ogawa, MD PhD, Hideki Makishima, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1709.
https://doi.org/10.1182/blood-2019-122032
Published: 2019
Journal Articles

Mechanistic Insights into the Inhibition of T Regulatory Cells By Dasatinib May Predict Immunostimulatory Effects in CML Patients

Patrick Harrington, MRCP, FRCPath, Richard Dillon, MA, PhD MRCP, FRCPath, Philippe Rousselot, MD PhD, Deepti Radia, Yvonne Francis, Claire N Harrison, Professor, Shahram Kordasti, MD PhD, Hugues De Lavallade
Journal: Blood
Blood (2019) 134 (Supplement_1): 1635.
https://doi.org/10.1182/blood-2019-129135
Published: 2019
Journal Articles

Acquired Platelet GPVI Dysfunction As Possible Predictor for Early Sepsis Diagnosis and Poor Outcome

Lukas J Weiss, Georgi Manukjan, PhD, Nils Nagler, Markus Kredel, MD, Thien-Tri Lam, MD, Bernhard Nieswandt, PhD, Dirk Weismann, MD, Harald Schulze, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3609.
https://doi.org/10.1182/blood-2019-131088
Published: 2019
Journal Articles

Evidence of Endothelial Dysfunction and Activation of RhoA/Rho Kinase Pathway in Inflammatory Bowel Disease

Jaime Pereira, MD, Claudia G Saez, PhD, Manuel Alvarez, MD, Felipe Silva, MD, Nixa Olivares, Jose G Valenzuela, Antonia Pastore, Diego Mezzano, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3641.
https://doi.org/10.1182/blood-2019-126033
Published: 2019
Journal Articles

Hotspot U2AF1 Mutations Determine Missplicing Selectivity: Novel Mechanisms Altering Splicing Factors

Vera Adema, PhD, Courtney E Hershberger, BS, Wencke Walter, PhD, Cassandra M Kerr, MS, Stephan Hutter, PhD, Yasunobu Nagata, MD PhD, Hassan Awada, Sunisa Kongkiatkamon, Christina Snider, Milo Co, Manja Meggendorfer, PhD, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Francesc Sole, PhD, Richard A Padgett, PhD, Torsten Haferlach, MD, Jaroslaw P. Maciejewski, MD PhD, Valeria Visconte, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2985.
https://doi.org/10.1182/blood-2019-129367
Published: 2019
Journal Articles

Protein Arginine Methyltransferase 1 (PRMT1) Dampens Self-Renewal and Promotes Differentiation of Hematopoietic Stem Cells in Mouse Models

Hairui Su, PhD, Szu-Mam Liu, PhD, Chiao-Wang Sun, PhD, Mark T. Bedford, PhD, Xinyang Zhao, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2460.
https://doi.org/10.1182/blood-2019-127226
Published: 2019
Journal Articles

Targeting T-ALL Cells with Potent Activators of the PP2A Protein Phosphatase Tumor Suppressor

Ken Morita, MD PhD, Shuning He, PhD, Radosław P. Nowak, PhD, Jinhua Wang, PhD, Nathanael Gray, PhD, Eric S. Fischer, PhD, A. Thomas Look, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 406.
https://doi.org/10.1182/blood-2019-123573
Published: 2019
Journal Articles

Dynamic Assembly of a Feedback Complex to Regulate Oncogenic B-Cell Receptor-Signaling

Jaewoong Lee, PhD, Kohei Kume, PhD, Zhengshan Chen, MD PhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Liting Chen, PhD, Lai N Chan, PhD, Lars Klemm, MS, Chun-Wei David Chen, PhD, Ning Ma, PhD, Wing C. Chan, MD, Stephen J Forman, MD, Francesca Zammarchi, PhD, Patrick Van Berkel, PhD, Ari Melnick, MD, Vu N Ngo, PhD, Huimin Geng, PhD, Selina M. Luger, MD FRCPC, Mark Litzow, MD, Michael T McManus, PhD, Nagarajan Vaidehi, PhD, Elisabeth M. Paietta, PhD, Eric Meffre, PhD, David M. Weinstock, MD, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 393.
https://doi.org/10.1182/blood-2019-131270
Published: 2019
Journal Articles

Characterization of Monoclonal Gammopathy of Undetermined Significance Progression to Multiple Myeloma through Meta-Analysis of GEO Data

Jihad Aljabban, MMSc, BA, David Chen, BS, Francesca Cottini, MD, Saad Syed, BS, Nabeal Aljabban, BS, Sharjeel Syed, BS, Tiffany Hughes, PhD, David Feldman, BS, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4395.
https://doi.org/10.1182/blood-2019-129699
Published: 2019
Journal Articles

Targeting Unique Synthetic Lethal Interactions between PI3K and MYC in B-ALL

Gang Xiao, PhD, Kohei Kume, PhD, Huimin Geng, PhD, Than Than Han, MS, Lars Klemm, MS, Markus Müschen, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3785.
https://doi.org/10.1182/blood-2019-128719
Published: 2019
Journal Articles

Identifying Novel Mechanisms of Resistance to Tyrosine Kinase Inhibitors in Anaplastic Large Cell Lymphoma

Elif Atabay, PhD, Qi Wang, PhD, Ambrogio Chiara, PhD, Taek-Chin Cheong, PhD, Silvia Peola, Geeta G Sharma, PhD, Luca Mologni, PhD, Carlo Gambacorti-Passerini, MD, Claudia Voena, PhD, Roberto Chiarle, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5060.
https://doi.org/10.1182/blood-2019-132188
Published: 2019
Journal Articles

RMC-4550, an Allosteric Inhibitor of SHP2, Displays Therapeutic Efficacy in Pre-Clinical Models of Myeloproliferative Neoplasms

Garima Pandey, Nathan Horvat, Narmin E. Amin, Afua A. Akuffo, Christelle Colin, Pearlie K. Epling-Burnette, Gary W. Reuther
Journal: Blood
Blood (2019) 134 (Supplement_1): 4198.
https://doi.org/10.1182/blood-2019-128937
Published: 2019
Journal Articles

KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia Cells Undergo ER-Stress-Induced Apoptosis Following Exposure to Proteasome Inhibitors

Wonil Kim, PhD, Cary S. Koss, BS, Tanja A. Gruber, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1283.
https://doi.org/10.1182/blood-2019-127699
Published: 2019
Journal Articles

Overexpression and Targeted Activation of the Protein Phosphatases SHP-1 Abrogates Survival Pathways in Large Granular Lymphocyte Leukemia (LGLL)

Mario Angelo Pagano, Elena Tibaldi, Giulia Calabretto, Antonella Teramo, Luca Dell'Amico, Gabriella Donà, Gregorio Barilà, Cristina Vicenzetto, Vanessa Rebecca Gasparini, Valentina Trimarco, Monica Facco, Francesco Piazza, Gianpietro Semenzato, Anna Maria Brunati, Renato Zambello
Journal: Blood
Blood (2019) 134 (Supplement_1): 2798.
https://doi.org/10.1182/blood-2019-129883
Published: 2019
Journal Articles

The Role of Protein Tyrosine Phosphatase PTP4A3 in T-Cell Acute Lymphoblastic Leukemia Progression

Min Wei, MSc, Jessica Blackburn, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2539.
https://doi.org/10.1182/blood-2019-126256
Published: 2019
Journal Articles

Ibrutinib Selects for Cells with Elevated Reactive Oxygen Species and Downregulated Phosphatases

Nathan Camp, PhD, Meghan Garrett, Ajay K. Gopal, MD, Richard James, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3795.
https://doi.org/10.1182/blood-2019-124454
Published: 2019
Journal Articles

Modelling Single Cell B-Cell Receptor Signaling Reveals Enhanced Activity in Primary CLL Cells Compared to Non-Malignant Cells While Fundamental Network Circuit Topology Remains Stable Even with Novel Therapeutic Inhibitors

Daniel Mertens, PhD, Christine Wolf, PhD, Carsten Maus, PhD, Michael Persicke, Katharina Filarsky, PhD, Hartmut Döhner, Peter Lichter, PhD, Thomas Höfer, PhD, Stephan Stilgenbauer, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4275.
https://doi.org/10.1182/blood-2019-127837
Published: 2019
Journal Articles

Genome-Wide CRISPR Screening in Acute Myeloid Leukemia Cells Identifies Genes in the PI3K/AKT/mTOR and MEK/ERK Pathways That Define Sensitivity to Trametinib

Tamilla Nechiporuk, PhD, Alisa Damnernsawad, PhD, Daniel Bottomly, MS, Quinlan Morrow, BS, Suyoun Choi, Sofia Beer, Stephen E Kurtz, PhD, Shannon K. McWeeney, PhD, Jeffrey W. Tyner
Journal: Blood
Blood (2019) 134 (Supplement_1): 1395.
https://doi.org/10.1182/blood-2019-129117
Published: 2019