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Journal Articles

The Tetraspanin CD53 Regulates Early B Cell Development By Promoting IL-7R Signaling

Zev J. Greenberg, BS, Darlene A. Monlish, PhD, Rachel L. Bartnett, Jeffrey J. Bednarski, MD PhD, Laura G. Schuettpelz, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 79.
https://doi.org/10.1182/blood-2019-131641
Published: 2019
Journal Articles

AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia

Greta De Jong, Sophie E Levie, Remko Schotte, PhD, Wouter Pos, PhD, Daniel Go, Etsuko Yasuda, Madalina Cercel, Susan E van Hal-van Veen, Esmay Frankin, Anikó Szabó, MD, Julien Villaudy, PhD, Pauline M van Helden, PhD, Hans van Eenennaam, PhD, Hergen Spits, PhD, Anita W Rijneveld, MD PhD, Mette D Hazenberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4461.
https://doi.org/10.1182/blood-2019-127894
Published: 2019
Journal Articles

Modulation of CD81 By Epigenetic Drug Combination Sensitizes Acute Lymphoblastic Leukemia Via Decreased BTK Signaling

Anthony Quagliano, BS, Anilkumar Gopalakrishnapillai, PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 2628.
https://doi.org/10.1182/blood-2019-129198
Published: 2019
Journal Articles

High frequency of inactivating tetraspanin C D37 mutations in diffuse large B-cell lymphoma at immune-privileged sites

Brief Report
Suraya Elfrink, Charlotte M. de Winde, Michiel van den Brand, Madeleine Berendsen, Margaretha G. M. Roemer, Frank Arnold, Luuk Janssen, Alie van der Schaaf, Erik Jansen, Patricia J. T. A. Groenen, Astrid Eijkelenboom, Wendy Stevens, Corine J. Hess, J. Han van Krieken, Joost S. P. Vermaat, Arjen H. G. Cleven, Ruben A. L. de Groen, Viviana Neviani, Daphne de Jong, Sjoerd van Deventer, Blanca Scheijen, Annemiek B. van Spriel
Journal: Blood
Blood (2019) 134 (12): 946–950.
https://doi.org/10.1182/blood.2019001185
Published: 2019
Includes: Supplemental data
Journal Articles

Regulation of Homeostatic and Malignant B Cell Development By the Tetraspanin CD53

Zev J. Greenberg, BS, Darlene A. Monlish, PhD, Rachel L. Bartnett, Laura G. Schuettpelz, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3699.
https://doi.org/10.1182/blood-2018-99-111957
Published: 2018
Journal Articles

CD37 Expression in Acute Myeloid Leukemia Provides New Target for Directed Therapy

Karilyn Larkin, MD, Erin Guth, MS, Bonnie K. Harrington, DVM, Nicole Grieselhuber, MD PhD, Natarajan Muthusamy, DVM, PhD, John C. Byrd, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4056.
https://doi.org/10.1182/blood-2018-99-117262
Published: 2018
Journal Articles

The Impact of Immunotherapy on Tumor Evolution

Andrei Thomas-Tikhonenko, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): SCI-18.
https://doi.org/10.1182/blood-2018-99-109434
Published: 2018
Journal Articles

Duohexabody-CD37, a Novel Bispecific Antibody with a Hexamerization-Enhancing Mutation Targeting CD37, Demonstrates Superior Complement-Dependent Cytotoxicity in Preclinical B-Cell Malignancy Models

Simone C. Oostindie, MSc, Hilma J. Van Der Horst, MSc, Marije B. Overdijk, PhD, Kristin Strumane, PhD, Sandra Verploegen, PhD, Margaret A. Lindorfer, PhD, Erica M. Cook, B.A., Martine E.D. Chamuleau, MD, Tuna Mutis, PhD, Janine Schuurman, PhD, A. Kate Sasser, PhD, Ronald P. Taylor, PhD, Paul W. H. I. Parren, PhD, Frank J. Beurskens, PhD, Esther C. W. Breij, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4170.
https://doi.org/10.1182/blood-2018-99-114723
Published: 2018
Journal Articles

Targeting CD37 in B-Cell Malignancies Using the Novel Therapeutic Duohexabody-CD37 Results in Efficient Killing of Tumor B-Cells Ex Vivo Via Complement-Dependent Cytotoxicity, Even in Relapsed and/or Refractory Patient Samples

Hilma J. Van Der Horst, MSc, Simone C. Oostindie, MSc, Saskia AGM Cillessen, MSc, Anne T Gelderloos, MSc, Marije B Overdijk, Martine E.D. Chamuleau, MD, Esther C. W. Breij, PhD, Tuna Mutis, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4179.
https://doi.org/10.1182/blood-2018-99-115886
Published: 2018
Journal Articles

Epigenetic Drug Combination Overcomes Bone Marrow Microenvironment-Induced Chemoprotection in Pediatric Acute Lymphoblastic Leukemia Via Modulation of CD81

Anthony Quagliano, BS, Anilkumar Gopalakrisnapillai, PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 3957.
https://doi.org/10.1182/blood-2018-99-120275
Published: 2018
Journal Articles

Targeting Aberrant Expression of CD81 Impacts Cell Adhesion and Migration, Drug Resistance and Prognosis of Acute Myeloid Leukemia

Fanny Gonzales, Thomas Boyer, Pauline Peyrouze, Soizic Guihard, Christophe Roumier, Céline Berthon, MD PhD, Claude Preudhomme, PharmD, PhD, Meyling Cheok, BSPharm, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2675.
https://doi.org/10.1182/blood.V130.Suppl_1.2675.2675
Published: 2017
Journal Articles

CD9 Blockade Effectively Suppresses Disease Progression of Pediatric B-Precursor Acute Lymphoblastic Leukemia and Enhances Chemosensitivity

Chi Zhang, MSc, Kam Tong Leung, PhD, Karen Li, PhD, Kathy Yuen Yee Chan, PhD, Alex Wing Kwan Leung, MRCPCH, John Tak Kit Cheung, BSc, Frankie Wai Tsoi Cheng, MD, Chi Kong Li, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1327.
https://doi.org/10.1182/blood.V130.Suppl_1.1327.1327
Published: 2017
Journal Articles

Phosphoproteomic Landscaping Unveils Constitutive cKIT Activation in Human Erythroblasts from Polycythemia Vera (PV) Patients

Lilian Varricchio, PhD, Giulia Federici, PhD, Francesca Masiello, MS, Fabrizio Martelli, PhD, Mario Falchi, PhD, Orietta Picconi, Gabriella Girelli, MD, Agostino Tafuri, MD, Emanuel Petricoin III, PhD, Ann Zeuner, PhD, Anna Rita Migliaccio, PhD
Journal: Blood
Blood (2016) 128 (22): 399.
https://doi.org/10.1182/blood.V128.22.399.399
Published: 2016
Journal Articles

BI 836826, a Novel Fc-Engineered Antibody in Combination with Phosphoinositide-3-Kinase Inhibitor for Treatment of High Risk Chronic Lymphocytic Leukemia and Lymphoma

Deborah M Stephens, DO, Kyle A. Beckwith, PhD, Priscilla Do, BS, Carolyn Cheney, BS, Xiaokui Mo, PhD MAS, Karilyn Larkin, MD, Jeffrey Jones, MD MPH, Farrukh T. Awan, Laura Grosmaire, PhD, Randy Jones, PhD, Julie DiPaolo, PhD, Stacey Tannheimer, Karl-Heinz Heider, PhD, John C. Byrd, MD, Natarajan Muthusamy, DVM, PhD
Journal: Blood
Blood (2016) 128 (22): 2767.
https://doi.org/10.1182/blood.V128.22.2767.2767
Published: 2016
Journal Articles

Treating B Cell Lymphomas with Anti CD81 Antibodies

Felipe Vences-Catalan, PhD, Chiung-Chi Kuo, MsC, Ranjani Rajapaksa, PhD, Caroline Duault, PhD, Ronald Levy, MD, Shoshana Levy, PhD
Journal: Blood
Blood (2016) 128 (22): 4180.
https://doi.org/10.1182/blood.V128.22.4180.4180
Published: 2016
Journal Articles

The Tetraspanin CD9 Regulates Engraftment and Mobilization of Human CD34+ Hematopoietic Stem/Progenitor Cells and Modulates VLA-4 Activity

Kam Tong Leung, PhD, Karen Li, PhD, Yorky Tsin Sik Wong, BSc, Kathy Yuen Yee Chan, PhD, Xiao-Bing Zhang, PhD, Alex Wing Kwan Leung, MRCPCH, Tak Yeung Leung, MD, Kam Sze Tsang, PhD, Pak Cheung Ng, MD FRCPCH, Chi Kong Li, MD
Journal: Blood
Blood (2015) 126 (23): 1169.
https://doi.org/10.1182/blood.V126.23.1169.1169
Published: 2015
Journal Articles

The Role of Tetraspanin CD37 in B-Cell Malignancy

Kyle A. Beckwith, BS, Erich I. Williams, BS, Mark D. Wright, PhD, Annemiek B. van Spriel, PhD, John C. Byrd, MD, Natarajan Muthusamy, DVM, PhD
Journal: Blood
Blood (2015) 126 (23): 1258.
https://doi.org/10.1182/blood.V126.23.1258.1258
Published: 2015
Journal Articles

Roles of Exosomes in the Hematopoietic Stem Cell-Supporting Capacity of Stromal Cells

Gregoire Stik, PhD, Simon Crequit, Jennifer Durant, Laurence Petit, Pierre Charbord, MD, Thierry Jaffredo, PhD, Charles Durand, PhD
Journal: Blood
Blood (2015) 126 (23): 1193.
https://doi.org/10.1182/blood.V126.23.1193.1193
Published: 2015
Journal Articles

A Phase 1 Study of the Anti-CD37 Antibody-Drug Conjugate AGS67E in Advanced Lymphoid Malignancies. Interim Results

Ahmed Sawas, MD, Kerry J. Savage, MDMSc, Raymond Perez, MD, Ranjana H Advani, MD, Anna Butturini, MD, Jacqueline Lackey, Fabio Trave, MD, Banmeet Anand, PhD, Yao Huang, Leonard Reyno, MD, Owen A. O'Connor, MD
Journal: Blood
Blood (2015) 126 (23): 3976.
https://doi.org/10.1182/blood.V126.23.3976.3976
Published: 2015
Journal Articles

The Tetraspanin CD81 Facilitates Tumor Metastasis By Modulating Immune Suppression

Felipe Vences Catalan, PhD, Ranjani Rajapaksa, PhD, Minu K. Srivastava, PhD, Aurelien Marabelle, MD PhD, Shoshana Levy, PhD
Journal: Blood
Blood (2014) 124 (21): 4136.
https://doi.org/10.1182/blood.V124.21.4136.4136
Published: 2014