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Journal Articles

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

Ethel Cesarman, MD PhD, Mikhail Roshal, MD PhD, Jonathan Reichel, PhD, Wagner Florian, PhD, Bhavneet Binder, Sakellarios Zairis, Jouliana Sadek, PhD, Joshua Brody, MD, Raul Rabadan, PhD, Sandeep Dave, MD

Blood (2019) 134 (Supplement_1): 549.

https://doi.org/10.1182/blood-2019-131163

Published: 2019

Journal Articles

VAV1 Mutations Contributes to the Development of T-Cell Malignancies in Mice

Kota Fukumoto, MD, Mamiko Sakata-Yanagimoto, MD PhD, Manabu Fujisawa, MD, Tatsuhiro Sakamoto, MD PhD, Tran B. Nguyen, Sakurako Suma, MD, Hiroaki Miyoshi, MD PhD, Koichi Ohshima, MD PhD, Keisuke Kataoka, MD PhD, Seishi Ogawa, MD PhD, Shigeru Chiba, MD PhD

Blood (2019) 134 (Supplement_1): 300.

https://doi.org/10.1182/blood-2019-124591

Published: 2019

Journal Articles

Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes

Ipsita Pal, PhD, Yu Ri Kim, MD, Sohani Das Sharma, PhD, Prabhjot S. Mundi, MD, Andre M. Grilo, PhD, Luke E Berchowitz, PhD, Mingzhao Zhu, PhD, Hull G. Kenneth, PhD, Daniel Romo, PhD, Owen O'Connor, MD PhD, Marko Jovanovic, PhD, Changchun Deng, MD PhD

Blood (2019) 134 (Supplement_1): 4067.

https://doi.org/10.1182/blood-2019-131816

Published: 2019

Journal Articles

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Liping Li, MD PhD, Wenyan Lu, PhD, Alison R. Moliterno, MD, Lingling Xian, MD PhD, Joseph Kim, BS, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 1680.

https://doi.org/10.1182/blood-2019-130262

Published: 2019

Journal Articles

Deletions of 5q Promote Genome Instability in TP53-Mutant MDS/AML

Andreea Reilly, Stephanie Busch, B.S., Janis L. Abkowitz, MD, Pamela S. Becker, MD PhD, Sergei Doulatov, PhD

Blood (2019) 134 (Supplement_1): 1244.

https://doi.org/10.1182/blood-2019-127038

Published: 2019

Journal Articles

Targeting GSK3: beyond the mitotic spindle?

C. Steidl

Blood (2019) 134 (4): 333–334.

https://doi.org/10.1182/blood.2019001638

Published: 2019

Journal Articles

PDZ Binding Kinase (PBK) - a Novel Gene Driving Genomic Evolution in Multiple Myeloma

Subodh Kumar, PhD, Leutz Buon, Srikanth Talluri, PhD, Jialan Shi, MD PhD, Hervé Avet-Loiseau, MD PhD, Mehmet Kemal Samur, PhD, Masood A. Shammas, PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 4474.

https://doi.org/10.1182/blood-2018-99-119186

Published: 2018

Journal Articles

Transcriptomic Profiling of Circulating Tumor Cells (CTCs) in Multiple Myeloma (MM): A New Model to Understand Disease Dissemination

Blood (2018) 132 (Supplement 1): 245.

https://doi.org/10.1182/blood-2018-99-113331

Published: 2018

Journal Articles

Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse

Kristine Misund, PhD, Davine Hofste Op Bruinink, MD, Eivind Coward, PhD, Remco Hoogenboezem, MSc, Even H Rustad, MD, Eivind Hovig, PhD, Anders Sundan, PhD, Ola Myklebost, PhD, Pieter Sonneveld, MD PhD, Anders Waage, MD PhD

Blood (2018) 132 (Supplement 1): 3157.

https://doi.org/10.1182/blood-2018-99-113553

Published: 2018

Journal Articles

C-Terminal BRE Overexpression in 11q23-Rearranged and t(8;16) Acute Myeloid Leukemia Is Caused By Intragenic Transcription Initiation

Blood (2017) 130 (Supplement 1): 3810.

https://doi.org/10.1182/blood.V130.Suppl_1.3810.3810

Published: 2017

Journal Articles

Delayed Globin Synthesis Leads to Excessive Heme and the Macrocytic Anemia of Diamond Blackfan Anemia and del(5q) Myelodysplastic Syndrome

Janis L. Abkowitz, MD, Raymond T Doty, PhD, Zhantao Yang, MD, Xiaowei Yan, PhD, Christopher Lausted, MS, Qiang Tian, MD PhD

Blood (2017) 130 (Supplement 1): SCI-18.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-18.SCI-18

Published: 2017

Journal Articles

Development of a Novel Class of Microtubule Destabilizing Agents with Selectivity Against Diffuse Large B-Cell Lymphoma (DLBCL) with B-Cell Receptor (BCR) Activation

Benet Pera Gresely, PhD, Francisco de Asís Balaguer, BS, Mariano Gonzalo Cardenas, PhD, Maria Victoria Revuelta, PhD, Maria Nieves Calvo Vidal, PhD, Rossella Marullo, MD PhD, Nahuel Zamponi, PhD, Ildefonso Ismael Rodriguez Rivera, MD, Yong Ai, PhD, Joseph Fraser Glickman, MSPH, PhD, Isabel Barasoain, PhD, Fernando Díaz, PhD, Ari Melnick, MD, Fengtian Xue, PhD, Leandro Cerchietti, MD

Blood (2017) 130 (Supplement 1): 2546.

https://doi.org/10.1182/blood.V130.Suppl_1.2546.2546

Published: 2017

Journal Articles

Starvation Stress in the Sbds -Null Zebrafish: Implications for Human Shwachman-Diamond Syndrome

Usua Oyarbide, PhD, Wilmer Amaya-Mejia, BS, Michael Waters, BS, Jacek Topczewski, PhD, Seth Corey, MD

Blood (2017) 130 (Supplement 1): 2459.

https://doi.org/10.1182/blood.V130.Suppl_1.2459.2459

Published: 2017

Journal Articles

High Aurora Kinase and Low Dido Levels Characterizes a Sub-Group of Chronic Lymphocytic Leukemia with Chromosomal Gains and High White Blood Cell Counts: Potential Inter-Regulatory Role of E2F1 and Mir-17-92 Cluster

Felipe C Souza, Msc., Josiane L Schiavinato, PhD, Antonio R. Lucena-Araujo, PhD, Fabio M Oliveira, PhD, Amelia G Araújo, Dimas Tadeu Covas, MD, PhD, Carlos Martínez-A, PhD, Marco A Zago, MD PhD, Rodrigo A Panepucci, PhD

Blood (2016) 128 (22): 2029.

https://doi.org/10.1182/blood.V128.22.2029.2029

Published: 2016

Journal Articles

Aurora Kinase a: A New Component of Imatinib Resistance in Chronic Myeloid Leukemia

Manuela Mancini, PhD, Simona Soverini, Elisa Leo, PhD, Fausto Castagnetti, PhD, Caterina De Benedittis, PhD, Gabriele Gugliotta, PhD, Gianantonio Rosti, MD, Maria Alessandra Santucci, MD, Michele Cavo, Giovanni Martinelli, MD PhD

Blood (2015) 126 (23): 1573.

https://doi.org/10.1182/blood.V126.23.1573.1573

Published: 2015

Journal Articles

Alisertib, an Aurora a Kinase Inhibitor, Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma Cells

Steven I. Park, MD, Carolina P. Lin, MS, Dirk P. Dittmer, PhD, Steven P. Angus, PhD, Greg G. Wang, PhD, Yuri D. Fedoriw, MD, David B. Darr, BS, Daniel P. Roth, BS, Norman E. Sharpless, MD, Blossom Damania, PhD

Blood (2015) 126 (23): 1551.

https://doi.org/10.1182/blood.V126.23.1551.1551

Published: 2015

Journal Articles

Results from a Phase 1 Study and Expanded Cohort of an Interrupted Dosing Schedule of the Aurora Kinase a Inhibitor MLN8237 Combined with Vorinostat in Lymphoid Malignancies

Tanya Siddiqi, MD, Anna Scuto, PhD, Jan H. Beumer, PharmD, PhD, Joo Y. Song, MD, Paul Frankel, PhD, Chris Ruel, MS, Jacob Cobb, BS, Brian F. Kiesel, BS, Dennis D. Weisenburger, MD, Kevin R. Kelly, MD PhD, Joseph Tuscano, MD, Leslie Popplewell, MD, Stephen J. Forman, MD, Richard Piekarz, PhD MD, Edward M. Newman, PhD

Blood (2015) 126 (23): 2731.

https://doi.org/10.1182/blood.V126.23.2731.2731

Published: 2015

Journal Articles

A Striking Reduction of Monoclonal Protein in a Patient with Concurrent Plasma Cell Dyscrasia and CMML-2, after Treatment with Rigosertib (01910.Na)

Jamile M. Shammo, MD, Agne Paner, MD, MV Ramana Reddy, PhD, Rachel L Mitchell, MD, Parameswaran Venugopal, MD

Blood (2015) 126 (23): 5362.

https://doi.org/10.1182/blood.V126.23.5362.5362

Published: 2015

Journal Articles

Filanesib (ARRY-520) Demonstrates Potent and Rapid Activity in Preclinical Models of MM, Dependent on Bcl-2 Family Expression, and Synergistic with Dexamethasone and IMiDs

Susana Hernández-García, Laura San-Segundo, Lorena González-Méndez, Teresa Paíno, PhD, Ana Alicia López-Iglesias, MD, Montserrat Martín-Sánchez, Mercedes Garayoa, PhD BS, Michael J Humphries, PhD, Brian Tunquist, PhD BS, Maria-Victoria Mateos, Enrique M Ocio, MD PhD

Blood (2014) 124 (21): 4710.

https://doi.org/10.1182/blood.V124.21.4710.4710

Published: 2014

Journal Articles

A Phase II Study of MLN8237 (Alisertib) Alone and in Combination with Rituximab in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas (NHL)

Kami J. Maddocks, MD, Jonathon B. Cohen, MD, Beth Christian, MD, Joseph M Flynn, DO, MPH, Samantha M. Jaglowski, MD MPH, Kristie A. Blum, MD

Blood (2014) 124 (21): 3082.

https://doi.org/10.1182/blood.V124.21.3082.3082

Published: 2014

NARROW

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

VAV1 Mutations Contributes to the Development of T-Cell Malignancies in Mice

Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes

High Mobility Group A1 Chromatin Regulators: Key Epigenetic Switches and Therapeutic Targets Required for Leukemic Transformation in JAK2 Mutant MPN

Deletions of 5q Promote Genome Instability in TP53-Mutant MDS/AML

Targeting GSK3: beyond the mitotic spindle?

PDZ Binding Kinase (PBK) - a Novel Gene Driving Genomic Evolution in Multiple Myeloma

Transcriptomic Profiling of Circulating Tumor Cells (CTCs) in Multiple Myeloma (MM): A New Model to Understand Disease Dissemination

Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse

C-Terminal BRE Overexpression in 11q23-Rearranged and t(8;16) Acute Myeloid Leukemia Is Caused By Intragenic Transcription Initiation

Delayed Globin Synthesis Leads to Excessive Heme and the Macrocytic Anemia of Diamond Blackfan Anemia and del(5q) Myelodysplastic Syndrome

Development of a Novel Class of Microtubule Destabilizing Agents with Selectivity Against Diffuse Large B-Cell Lymphoma (DLBCL) with B-Cell Receptor (BCR) Activation

Starvation Stress in the Sbds -Null Zebrafish: Implications for Human Shwachman-Diamond Syndrome

High Aurora Kinase and Low Dido Levels Characterizes a Sub-Group of Chronic Lymphocytic Leukemia with Chromosomal Gains and High White Blood Cell Counts: Potential Inter-Regulatory Role of E2F1 and Mir-17-92 Cluster

Aurora Kinase a: A New Component of Imatinib Resistance in Chronic Myeloid Leukemia

Alisertib, an Aurora a Kinase Inhibitor, Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma Cells

Results from a Phase 1 Study and Expanded Cohort of an Interrupted Dosing Schedule of the Aurora Kinase a Inhibitor MLN8237 Combined with Vorinostat in Lymphoid Malignancies

A Striking Reduction of Monoclonal Protein in a Patient with Concurrent Plasma Cell Dyscrasia and CMML-2, after Treatment with Rigosertib (01910.Na)

Filanesib (ARRY-520) Demonstrates Potent and Rapid Activity in Preclinical Models of MM, Dependent on Bcl-2 Family Expression, and Synergistic with Dexamethasone and IMiDs

A Phase II Study of MLN8237 (Alisertib) Alone and in Combination with Rituximab in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas (NHL)

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American Society of Hematology

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ASH Publications

American Society of Hematology

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