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Journal Articles

Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease

Blood (2021) 137 (17): 2403–2416.

https://doi.org/10.1182/blood.2020008720

Published: 2021

Includes: Supplemental data

Journal Articles

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

Amandeep Kaur, PhD, Katherine M Hannan, PhD, Samina Nazir, MSc, Kylee H Maclachlan, FRACP,FRCPA, Gretchen Poortinga, PhD, Si Ming Man, PhD, Simon Harrison, MBBS, MRCP, FRCPath, FRACP, PhD, Ross D Hannan, PhD, Elizabeth E. Gardiner, PhD

Blood (2019) 134 (Supplement_1): 2360.

https://doi.org/10.1182/blood-2019-121713

Published: 2019

Journal Articles

CYT-0853, a Novel RAD51 Inhibitor, Modulates Immunoregulatory B-Lymphocytes

Tamar Aprahamian, PhD, ED Keniston, Jane Branca, Muneer G Hasham, PhD, Melinda Day, PhD, Kevin Mills, PhD

Blood (2019) 134 (Supplement_1): 2330.

https://doi.org/10.1182/blood-2019-131311

Published: 2019

Journal Articles

Towards Understanding & Uncovering New Key Players in T-Cell Development upon Aging

Hanane Boukarabila, PhD, Kalpana Nattamai, Medhanie Assmelash Mulaw, PhD, Hartmut Geiger, PhD

Blood (2019) 134 (Supplement_1): 2482.

https://doi.org/10.1182/blood-2019-127294

Published: 2019

Journal Articles

Mice Deficient in ß2-Glycoprotein I Have a Delayed Time to Thrombosis

Ravi Kumar Alluri, PhD, Gabriel L Forbes, Suman Kundu, MBA, Alvin H. Schmaier, MD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 2423.

https://doi.org/10.1182/blood-2019-130521

Published: 2019

Journal Articles

Inhibiting Matrix Metalloproteinases Hinders Acute Myeloid Leukaemia and Prevents Healthy Stem Cell Loss

Chiara Pirillo, Myriam Haltalli, Sara Gonzalez-anton, George Adams, Delfim Duarte, Cristina Lo Celso

Blood (2019) 134 (Supplement_1): 2487.

https://doi.org/10.1182/blood-2019-129847

Published: 2019

Journal Articles

Differential Effects of HIV Protease Inhibitors on Release and Activation of Platelet-Derived TGF-β1: Potential Association with HIV-Linked CVD

Kouzbari Karim, DDS, Gostynska Sandra, MS, Sonia Elhadad, PhD, Dube Pratibha, MS, Jeffrey Laurence, MD, Jasimuddin Ahamed, PhD

Blood (2019) 134 (Supplement_1): 2341.

https://doi.org/10.1182/blood-2019-126225

Published: 2019

Journal Articles

Novel CD33 Antibodies Unravel Localization, Biology, and Therapeutic Implications of CD33 Isoforms

Mohammed Gbadamosi, BS, Tiffany A. Hylkema, BS, Soheil Meshinchi, MD PhD, Jatinder K Lamba, M.Sc., PhD

Blood (2019) 134 (Supplement_1): 908.

https://doi.org/10.1182/blood-2019-122596

Published: 2019

Journal Articles

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Sayantani Sinha, PhD, Ritama Gupta, PhD, Jianbing Zhang, PhD, Amaliris Guerra, PhD, Ping La, Sara Gardenghi, PhD, Stefano Rivella, PhD

Blood (2019) 134 (Supplement_1): 940.

https://doi.org/10.1182/blood-2019-128826

Published: 2019

Journal Articles

Mechanism of Pulmonary Thrombosis in Hemolytic Disorders

Tomasz Brzoska, PhD, Margaret F. Bennewitz, PhD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Matthew D Neal, MD, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 976.

https://doi.org/10.1182/blood-2019-130592

Published: 2019

Journal Articles

Fas Mutations in Non-Hodgkin's Lymphoma (NHL): Implications for Disease Progression and Therapeutic Resistance

Ryan N Rys, BSc, BA, Maanasa Venkataraman, MSc, Jibin Zeng, MSc, Koren Kathleen Mann, PhD, Nathalie Johnson, MD

Blood (2019) 134 (Supplement_1): 1520.

https://doi.org/10.1182/blood-2019-130602

Published: 2019

Journal Articles

A New Mechanism for T-ALL Leukemogenesis: Early Expression of Alpha-Beta TCR Occurs in a Natural Subset of CD4-CD8- Double Negative (DN) Thymocytes Where MHC Engagement May Drive NOTCH Mutation and Tumor Initiation

Kimberly G Laffey, PhD, Robert J Stiles, BS, Melissa Ludescher, MS, Tessa Davis, MS, Shariq S Khwaja, MD, Richard J. Bram, MD, Peter J Wettstein, PhD, Venkataraman Ramachandran, MD, Cory E Johnson, BS, Richard Hammer, MD, Chi-Ren Shyu, PhD, Diana Gil, PhD, Adam G Schrum, PhD

Blood (2019) 134 (Supplement_1): 1463.

https://doi.org/10.1182/blood-2019-131897

Published: 2019

Journal Articles

Characterization of BCR-ABL Specific CD4+ T Cells and Their Role in Controlling Ph+ Acute Lymphoblastic Leukemia

Sean I. Tracy, MD PhD, Can Hekim, MSc,PhD, Michael Farrar, PhD

Blood (2019) 134 (Supplement_1): 1345.

https://doi.org/10.1182/blood-2019-124205

Published: 2019

Journal Articles

CD155-Tigit Pathway Modulation in Dendritic Cell/Acute Myeloid Leukemia Fusion Vaccine Model

Myrna Nahas, MD, Dina Stroopinsky, PhD, Marzia Capelletti, PhD MBBS, Jacalyn Rosenblatt, MD, Shira Orr, PhD, Haider Ghiasuddin, Adam Morin, Jessica Liegel, MD, Donald Kufe, MD, David E. Avigan, MD

Blood (2019) 134 (Supplement_1): 1386.

https://doi.org/10.1182/blood-2019-122438

Published: 2019

Journal Articles

Preliminary Clinical Data from a Phase 1 Trial with CPI-818, a Selective ITK Inhibitor That Preferentially Blocks the Growth of T Lymphoma Cells

Patrick P. Ng, PhD, Mehrdad Mobasher, MD MPH, Kitman S. Yeung, MS, Andrew N. Hotson, PhD, Craig M. Hill, PhD, Antonett Madriaga, MS, Trang P. Dao-Pick, MA, Erik Verner, PhD, Dejan Radeski, MBBS, FRACP, FRCPA, Michael S. Khodadoust, MD PhD, Youn H. Kim, MD, Richard A. Miller, MD, Joseph J. Buggy, PhD, James W. Janc, PhD

Blood (2019) 134 (Supplement_1): 1571.

https://doi.org/10.1182/blood-2019-127338

Published: 2019

Journal Articles

Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging

Kira Young, PhD, Elizabeth Eudy, BS, Matthew Loberg, BA, Rebecca Bell, BA, Jennifer Trowbridge, PhD

Blood (2019) 134 (Supplement_1): 526.

https://doi.org/10.1182/blood-2019-124534

Published: 2019

Journal Articles

Dll1 and Dll4 Notch Ligands Prime T Cell Alloimmunity and Are Expressed in Non-Overlapping Populations of Fibroblastic Stromal Cells in Spleen and Lymph Nodes at the Onset of Gvhd

Joshua D Brandstadter, MD PhD, Eric Perkey, Brian T. Gaudette, PhD, Léolène Carrington, PhD, Daniela Gomez-Atria, PhD, Bruce R. Blazar, MD, Burkhard Ludewig, PhD, Anastasia Tikhonova, PhD, Iannis Aifantis, PhD, David Allman, PhD, Ivan Maillard, MD PhD

Blood (2019) 134 (Supplement_1): 588.

https://doi.org/10.1182/blood-2019-123533

Published: 2019

Journal Articles

Innate Immune Mechanism of Hemarthrosis in Hemophilia-a Mice

Tomasz W. Kaminski, PharmD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Mark T Gladwin, MD, Prithu Sundd, PhD

Blood (2019) 134 (Supplement_1): 1043.

https://doi.org/10.1182/blood-2019-130471

Published: 2019

Journal Articles

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

Avik Dutta, PhD, Yue Yang, PhD, Bao Le, Golam Mohi, PhD

Blood (2019) 134 (Supplement_1): 1195.

https://doi.org/10.1182/blood-2019-132007

Published: 2019

Journal Articles

Therapeutic Doses of Recombinant FVIIa in Hemophilia Generates Thrombin in Platelet-Dependent and -Independent Manner

Shiva Keshava Gaddam Bala Krishna, PhD, Usha Pendurthi, PhD, L. Vijaya Mohan Rao, PhD

Blood (2019) 134 (Supplement_1): 1136.

https://doi.org/10.1182/blood-2019-128474

Published: 2019

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Targeting of canonical WNT signaling ameliorates experimental sclerodermatous chronic graft-versus-host disease

The Ribosomal Biogenesis Inhibitor CX-5461 Is an Anti-Cancer Therapeutic That Increases Platelet Count in Mice and in Humans

CYT-0853, a Novel RAD51 Inhibitor, Modulates Immunoregulatory B-Lymphocytes

Towards Understanding & Uncovering New Key Players in T-Cell Development upon Aging

Mice Deficient in ß2-Glycoprotein I Have a Delayed Time to Thrombosis

Inhibiting Matrix Metalloproteinases Hinders Acute Myeloid Leukaemia and Prevents Healthy Stem Cell Loss

Differential Effects of HIV Protease Inhibitors on Release and Activation of Platelet-Derived TGF-β1: Potential Association with HIV-Linked CVD

Novel CD33 Antibodies Unravel Localization, Biology, and Therapeutic Implications of CD33 Isoforms

Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions

Mechanism of Pulmonary Thrombosis in Hemolytic Disorders

Fas Mutations in Non-Hodgkin's Lymphoma (NHL): Implications for Disease Progression and Therapeutic Resistance

A New Mechanism for T-ALL Leukemogenesis: Early Expression of Alpha-Beta TCR Occurs in a Natural Subset of CD4-CD8- Double Negative (DN) Thymocytes Where MHC Engagement May Drive NOTCH Mutation and Tumor Initiation

Characterization of BCR-ABL Specific CD4+ T Cells and Their Role in Controlling Ph+ Acute Lymphoblastic Leukemia

CD155-Tigit Pathway Modulation in Dendritic Cell/Acute Myeloid Leukemia Fusion Vaccine Model

Preliminary Clinical Data from a Phase 1 Trial with CPI-818, a Selective ITK Inhibitor That Preferentially Blocks the Growth of T Lymphoma Cells

Decline in Insulin-like Growth Factor-1 (IGF1) from Aged Mesenchymal Stromal Cells Is a Targetable Mechanism to Rescue Hematopoietic Stem Cell Aging

Dll1 and Dll4 Notch Ligands Prime T Cell Alloimmunity and Are Expressed in Non-Overlapping Populations of Fibroblastic Stromal Cells in Spleen and Lymph Nodes at the Onset of Gvhd

Innate Immune Mechanism of Hemarthrosis in Hemophilia-a Mice

Critical Requirement of U2AF1 in the Maintenance and Function of Hematopoietic Stem Cells

Therapeutic Doses of Recombinant FVIIa in Hemophilia Generates Thrombin in Platelet-Dependent and -Independent Manner

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