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Journal Articles

Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway

Gael F. P. Bories, Scott Yeudall, Vlad Serbulea, Todd E. Fox, Brant E. Isakson, Norbert Leitinger

Blood (2020) 136 (13): 1535–1548.

https://doi.org/10.1182/blood.2020004964

Published: 2020

Includes: Supplemental data

Journal Articles

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

Etienne De Braekeleer, PhD MSc, Joanne Hsu, BS, Celine Hervieu, MSc, Konstantinos Tzelepis, PhD, Stefano Indraccolo, MD, Alan J. Warren, PhD FRCP, FRCPath, Irmela Jeremias, MD PhD, David Fernandez Antoran, PhD, Phil H Jones, PhD, Margaret A. Goodell, PhD, George S. Vassiliou

Blood (2018) 132 (Supplement 1): 2615.

https://doi.org/10.1182/blood-2018-99-118827

Published: 2018

Journal Articles

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

Gang Xiao, PhD, Chao Hong, PhD, Huimin Geng, PhD, Markus Muschen, MD

Blood (2017) 130 (Supplement 1): 882.

https://doi.org/10.1182/blood.V130.Suppl_1.882.882

Published: 2017

Journal Articles

Cigarette Smoking Is Associated with Adverse Outcome in Low Risk MDS Patients

Effie Rahman, Sarvari Venkata Yellapragada, Martha P. Mims, Kirtan Nautiyal, MD, Manuel Molina, MD, Gustavo A. Rivero, MD

Blood (2014) 124 (21): 5628.

https://doi.org/10.1182/blood.V124.21.5628.5628

Published: 2014

Journal Articles

Hematology from the Ground Up: Lessons from C. elegans

Iqbal Hamza, PhD

Blood (2013) 122 (21): SCI-16.

https://doi.org/10.1182/blood.V122.21.SCI-16.SCI-16

Published: 2013

Journal Articles

Association of A 313 g Glutathione S-Transferase P1 ( GSTP1 ) Inborn Polymorphism with Susceptibility to De Novo MDS

Sophia Zachaki, Chryssa Stavropoulou, Aggeliki Daraki, Marina Kalomoiraki, Panagoula Kollia, Vassiliki Aleporou, Gabriel Pantelias, Emmanuel Kanavakis, Constantina Sambani

Blood (2012) 120 (21): 1445.

https://doi.org/10.1182/blood.V120.21.1445.1445

Published: 2012

Journal Articles

Nrf2 Deficiency Leads to Reduced Hematopoietic Stem Cell Self-Renewal and Increased Sensitivity to Genotoxic Stressors Through Impaired P53 Function

Liang Li, PhD, Yin Wei Ho, Ling Li, PhD, Qin Huang, MD, PhD, Min Li, PhD, Stephen J. Forman, MD, Smita Bhatia, MD, MPH, Ravi Bhatia, MD

Blood (2012) 120 (21): 397.

https://doi.org/10.1182/blood.V120.21.397.397

Published: 2012

Journal Articles

Distinct Metabolic Dependency of Normal and Leukemic Cells in a Mouse Model

Blood (2011) 118 (21): 759.

https://doi.org/10.1182/blood.V118.21.759.759

Published: 2011

Journal Articles

ATM Mutant Lymphoid Tumour Cells Exhibit Impaired Activation of the Redox-Sensitive Nrf2-ARE Detoxification Pathway and Are Differentially Sensitive to Nrf2-Activating Compounds

Victoria J Weston, PhD, Angelo Agathanggelou, PhD, Paul AH Moss, MD, PhD, Pamela R. Kearns, BSc, MBBCh, MRCP, PhD, A. Malcolm R Taylor, PhD, Tatjana Stankovic, MD, PhD

Blood (2010) 116 (21): 49.

https://doi.org/10.1182/blood.V116.21.49.49

Published: 2010

Journal Articles

Germline Genetic Variation and Treatment Response on CCG-1891

Dana Sepe, MD, Thomas McWilliams, Jinbo Chen, PhD, Aaron Kershenbaum, PhD, Huaqing Zhao, Mei La, Meenakshi Davidas, PhD, Beverly Lange, MD, Timothy R. Rebbeck, PhD, Richard Aplenc, MD

Blood (2010) 116 (21): 2711.

https://doi.org/10.1182/blood.V116.21.2711.2711

Published: 2010

Journal Articles

Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Lineage Development.

Yukie Kawatani, Takafumi Suzuki, Ritsuko Shimizu, Vincent Kelly, Masayuki Yamamoto, MD, PhD

Blood (2009) 114 (22): 1993.

https://doi.org/10.1182/blood.V114.22.1993.1993

Published: 2009

Journal Articles

A Polymorphism Study on Detoxification and DNA Repair Genes in 700 MDS Patients Demonstrates An Association Between Genotype and An Aberrant Karyotype

C. Seedhouse, Stephanie Fischer, Christina Ganster, Christa Fonatsch, Peter Valent, MD, Ulrich Germing, Nigel H. Russell, MD, Detlef Haase, MD, PhD

Blood (2008) 112 (11): 2690.

https://doi.org/10.1182/blood.V112.11.2690.2690

Published: 2008

Journal Articles

Genetic Polymorphisms of DNA-Repair- and Detoxification Enzymes in Therapy-Related AML and MDS.

Stephanie Fischer, Claire Seedhouse, PhD, Thomas Schulz, PhD, Ulrich Germing, PhD, MD, Lorenz H. Truemper, PhD, MD, Detlef Haase, PhD, MD

Blood (2007) 110 (11): 4223.

https://doi.org/10.1182/blood.V110.11.4223.4223

Published: 2007

Journal Articles

Polymorphisms in Detoxification and DNA Repair Genes in Myelodysplastic Syndromes.

Claire H. Seedhouse, PhD, Stephanie Fischer, MD, Ulrich Germing, MD, Nigel Russell, MD, Detlef Haase, MD

Blood (2007) 110 (11): 2440.

https://doi.org/10.1182/blood.V110.11.2440.2440

Published: 2007

Journal Articles

Molecular Phenotype of Malignant CD34+ Hematopoietic Stem and Progenitor Cells in Chronic Myelogenous Leukemia.

Ralf Kronenwett, MD, Elena Diaz-Blanco, Thorsten Graef, MD, Ulrich Steidl, MD, Slawomir Kliszewski, Ingmar Bruns, Frank Neumann, MD, Simone Bork, Ulf Butterweck, Nicole Roes, Benedikt Brors, PhD, Roland Eils, PhD, Guido Kobbe, MD, Norbert Gattermann, MD, Rainer Haas, MD

Blood (2005) 106 (11): 2863.

https://doi.org/10.1182/blood.V106.11.2863.2863

Published: 2005

Journal Articles

Increased Frequency of Polymorphisms in XRCC3 and OGG1 Genes in Patients with MDS.

Hadrian Szpurka, MSc, Abdo Haddad, MD, Soumit Basu, MD, PhD, Mikkael Sekeres, MD, MSc, Jaroslaw P. Maciejewski, MD, PhD

Blood (2005) 106 (11): 3445.

https://doi.org/10.1182/blood.V106.11.3445.3445

Published: 2005

Journal Articles

Plasma Cell Gene-Expression Profiles in Patients with Systemic AL Amyloidosis: Responses to Melphalan and Stem Cell Transplant Are Associated with Differential Expression of Genes Involved in Translation, Protein Degradation and Detoxification.

Raymond L. Comenzo, MD, Ping Zhou, MD, PhD, Limin Wang, PhD, Stephen D. Nimer, MD, Adam B. Olshen, PhD

Blood (2005) 106 (11): 3405.

https://doi.org/10.1182/blood.V106.11.3405.3405

Published: 2005

Journal Articles

Identification and Characterization of Single Nucleotide Polymorphisms (SNPs) Associated with Genetic Predisposition to Develop Therapy-Related Acute Myeloid Leukemia (t-AML).

Vicent M. Guillem, PhD, Mar Tormo, MD, Jose Angel Martinez-Climent, MD, Ana Lluch, MD, Isabel Benet, MD, Marcos Gonzalez, MD, Josep Nomdedeu, MD, Javier Garcia-Conde, MD

Blood (2004) 104 (11): 3001.

https://doi.org/10.1182/blood.V104.11.3001.3001

Published: 2004

Journal Articles

Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia

Maria Teresa Voso, Francesco D'Alo', Rossana Putzulu, Luca Mele, Alessandra Scardocci, Patrizia Chiusolo, Roberto Latagliata, Francesco Lo-Coco, Sergio Rutella, Livio Pagano, Stefan Hohaus, Giuseppe Leone

Blood (2002) 100 (8): 2703–2707.

https://doi.org/10.1182/blood.V100.8.2703

Published: 2002

Journal Articles

Increased frequencies of glutathione S-transferase (GSTM1 and GSTT1) gene deletions in Korean patients with acquired aplastic anemia

Kyung A. Lee, Sun Hee Kim, Hee Yeon Woo, Young Joon Hong, Hyoun Chan Cho

Blood (2001) 98 (12): 3483–3485.

https://doi.org/10.1182/blood.V98.12.3483

Published: 2001

NARROW

Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway

The Nucleotide Kinase Nadk Is Required for ROS Detoxification and Constitutes a Metabolic Vulnerability of NOTCH1-Driven T-ALL

PON2 Exemplifies a Unique Dependency of B Cell Lineage ALL Cells on Detoxifying Lactonases

Cigarette Smoking Is Associated with Adverse Outcome in Low Risk MDS Patients

Hematology from the Ground Up: Lessons from C. elegans

Association of A 313 g Glutathione S-Transferase P1 ( GSTP1 ) Inborn Polymorphism with Susceptibility to De Novo MDS

Nrf2 Deficiency Leads to Reduced Hematopoietic Stem Cell Self-Renewal and Increased Sensitivity to Genotoxic Stressors Through Impaired P53 Function

Distinct Metabolic Dependency of Normal and Leukemic Cells in a Mouse Model

ATM Mutant Lymphoid Tumour Cells Exhibit Impaired Activation of the Redox-Sensitive Nrf2-ARE Detoxification Pathway and Are Differentially Sensitive to Nrf2-Activating Compounds

Germline Genetic Variation and Treatment Response on CCG-1891

Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Lineage Development.

A Polymorphism Study on Detoxification and DNA Repair Genes in 700 MDS Patients Demonstrates An Association Between Genotype and An Aberrant Karyotype

Genetic Polymorphisms of DNA-Repair- and Detoxification Enzymes in Therapy-Related AML and MDS.

Polymorphisms in Detoxification and DNA Repair Genes in Myelodysplastic Syndromes.

Molecular Phenotype of Malignant CD34+ Hematopoietic Stem and Progenitor Cells in Chronic Myelogenous Leukemia.

Increased Frequency of Polymorphisms in XRCC3 and OGG1 Genes in Patients with MDS.

Plasma Cell Gene-Expression Profiles in Patients with Systemic AL Amyloidosis: Responses to Melphalan and Stem Cell Transplant Are Associated with Differential Expression of Genes Involved in Translation, Protein Degradation and Detoxification.

Identification and Characterization of Single Nucleotide Polymorphisms (SNPs) Associated with Genetic Predisposition to Develop Therapy-Related Acute Myeloid Leukemia (t-AML).

Negative prognostic value of glutathione S-transferase (GSTM1 and GSTT1) deletions in adult acute myeloid leukemia

Increased frequencies of glutathione S-transferase (GSTM1 and GSTT1) gene deletions in Korean patients with acquired aplastic anemia

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American Society of Hematology

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American Society of Hematology

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