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Journal Articles

Targeting the KIT Activating Switch Control Pocket: A Novel Mechanism to Inhibit Mast Cell Activation and KIT D816V Neoplastic Mast Cell Proliferation

Geethani Bandara, PhD, Yun Bai, MS, Eunice Ching Chan, PhD, Irina Maric, MD, Olga Simakova, PhD, Scott C. Wise, MS, Daniel Flynn, PhD, Dean D Metcalfe, MD, Alasdair M Gilfillan, PhD, Todd M Wilson, DO
Journal: Blood
Blood (2011) 118 (21): 1740.
https://doi.org/10.1182/blood.V118.21.1740.1740
Published: 2011
Journal Articles

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

Jayme D. Allen, Zahara M. Jaffer, Su-Jung Park, Sarah Burgin, Clemens Hofmann, Mary Ann Sells, Shi Chen, Ethel Derr-Yellin, Elizabeth G. Michels, Andrew McDaniel, Waylan K. Bessler, David A. Ingram, Simon J. Atkinson, Jeffrey B. Travers, Jonathan Chernoff, D. Wade Clapp
Journal: Blood
Blood (2009) 113 (12): 2695–2705.
https://doi.org/10.1182/blood-2008-06-160861
Published: 2009
Includes: Supplemental data
Journal Articles

Phospholipase D1 regulates high-affinity IgE receptor-induced mast cell degranulation

Tomohiro Hitomi, Juan Zhang, Liliana M. Nicoletti, Ana Cristina G. Grodzki, Maria C. Jamur, Constance Oliver, Reuben P. Siraganian
Journal: Blood
Blood (2004) 104 (13): 4122–4128.
https://doi.org/10.1182/blood-2004-06-2091
Published: 2004
Journal Articles

P-21 Activated Kinase 1 (Pak1) Is Critical for Normal Mast Cell Degranulation and Cytokine Production in Response to Antigen Stimulation of the High Affinity IgE Receptor.

Jayme D. Allen, M.D., Clemens Hoffman, Ph.D, Ethel Derr-Yellin, Waylan Bessler, Fen-Chun Yang, M.D., Ph.D., David A. Ingram, M.D., Zahra Jaffer, Ph.D., Amanda Tipton, Johnathan Chernoff, M.D., Ph.D., D. Wade Clapp, M.D.
Journal: Blood
Blood (2004) 104 (11): 647.
https://doi.org/10.1182/blood.V104.11.647.647
Published: 2004
Journal Articles

NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and FcϵRI aggregation

Christine Tkaczyk, Vaclav Horejsi, Shoko Iwaki, Petr Draber, Lawrence E. Samelson, Anne B. Satterthwaite, Dong-Ho Nahm, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: Blood
Blood (2004) 104 (1): 207–214.
https://doi.org/10.1182/blood-2003-08-2769
Published: 2004
Journal Articles

The quantity and duration of FcRγ signals determine mast cell degranulation and survival

Sho Yamasaki, Eri Ishikawa, Masayuki Kohno, Takashi Saito
Journal: Blood
Blood (2004) 103 (8): 3093–3101.
https://doi.org/10.1182/blood-2003-08-2944
Published: 2004
Journal Articles

Increased Growth Promoting But Not Mast Cell Degranulation Potential of a Covalent Dimer of c-Kit Ligand

Karl H. Nocka, Beth A. Levine, Jone-Lone Ko, Peter M. Burch, Bryan E. Landgraf, Rita Segal, Robert Lobell
Journal: Blood
Blood (1997) 90 (10): 3874–3883.
https://doi.org/10.1182/blood.V90.10.3874
Published: 1997