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Alasdair M. Gilfillan
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Journal Articles

mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells

Daniel Smrž, Mi-Sun Kim, Shuling Zhang, Beverly A. Mock, Šárka Smržová, Wendy DuBois, Olga Simakova, Irina Maric, Todd M. Wilson, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: Blood
Blood (2011) 118 (26): 6803–6813.
https://doi.org/10.1182/blood-2011-06-359984
Published: 2011
Includes: Supplemental data
Journal Articles

Targeting the KIT Activating Switch Control Pocket: A Novel Mechanism to Inhibit Mast Cell Activation and KIT D816V Neoplastic Mast Cell Proliferation

Geethani Bandara, PhD, Yun Bai, MS, Eunice Ching Chan, PhD, Irina Maric, MD, Olga Simakova, PhD, Scott C. Wise, MS, Daniel Flynn, PhD, Dean D Metcalfe, MD, Alasdair M Gilfillan, PhD, Todd M Wilson, DO
Journal: Blood
Blood (2011) 118 (21): 1740.
https://doi.org/10.1182/blood.V118.21.1740.1740
Published: 2011
Journal Articles

Kit and FcϵRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells

Thomas R. Hundley, Alasdair M. Gilfillan, Christine Tkaczyk, Marcus V. Andrade, Dean D. Metcalfe, Michael A. Beaven
Journal: Blood
Blood (2004) 104 (8): 2410–2417.
https://doi.org/10.1182/blood-2004-02-0631
Published: 2004
Journal Articles

NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and FcϵRI aggregation

Christine Tkaczyk, Vaclav Horejsi, Shoko Iwaki, Petr Draber, Lawrence E. Samelson, Anne B. Satterthwaite, Dong-Ho Nahm, Dean D. Metcalfe, Alasdair M. Gilfillan
Journal: Blood
Blood (2004) 104 (1): 207–214.
https://doi.org/10.1182/blood-2003-08-2769
Published: 2004