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Journal Articles

Long-Term Safety and Efficacy of Mitapivat (AG-348), a Pyruvate Kinase Activator, in Patients with Pyruvate Kinase Deficiency: The DRIVE PK Study

Rachael F. Grace, MD, D. Mark Layton, MB BS, FRCP, FRCPCH, Frédéric Galactéros, MD PhD, Wilma Barcellini, MD, Eduard J. van Beers, MD PhD, Hassan M. Yaish, MD, Yaddanapudi Ravindranath, MBBS, Kevin H. M. Kuo, MDMSc,FRCPC, Sujit Sheth, MD, Janet L. Kwiatkowski, MD MSCE, Lei Hua, PhD, Peter F. Hawkins, PhD, Chris Mix, MD, Bertil Glader, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3512.
https://doi.org/10.1182/blood-2019-123406
Published: 2019
Journal Articles

Genotype-Response Correlation in DRIVE PK, a Phase 2 Study of AG-348 in Patients with Pyruvate Kinase Deficiency

Charles Kung, PhD, Penelope A. Kosinski, MS, Heidi Mangus, BS, Lei Hua, PhD, Gary Connor, Michelle Mobilia, BS, Karen Sullivan, BA, Sasha Frye, BS, Marie-Hélène Jouvin, MD, Rachael F. Grace, MD, Bertil Glader, MD, Chris Bowden, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3621.
https://doi.org/10.1182/blood-2018-99-111166
Published: 2018
Journal Articles

Results Update from the DRIVE PK Study: Effects of AG-348, a Pyruvate Kinase Activator, in Patients with Pyruvate Kinase Deficiency

Rachael F. Grace, MD, D. Mark Layton, MB, FRCP, Frédéric Galactéros, MDPhD, Christian Rose, MD, Wilma Barcellini, MD, D. Holmes Morton, MD, Eduard J. Van Beers, MD, Hassan M. Yaish, MD, Yaddanapudi Ravindranath, MBBS, Kevin H.M. Kuo, MD MSc, FRCPC, Sujit Sheth, MD, Janet L. Kwiatkowski, MD, Bruce Silver, MD, Charles Kung, Marvin Cohen, Hua Yang, Penelope A. Kosinski, MS, Lei Hua, Ann Barbier, Bertil Glader, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2194.
https://doi.org/10.1182/blood.V130.Suppl_1.2194.2194
Published: 2017
Journal Articles

Effects of AG-348, a Pyruvate Kinase Activator, on Anemia and Hemolysis in Patients with Pyruvate Kinase Deficiency: Data from the DRIVE PK Study

Rachael F Grace, MD, Christian Rose, D Mark Layton, Hassan M Yaish, Wilma Barcellini, Frédéric Galactéros, D Holmes Morton, Yaddanapudi Ravindranath, Kevin H.M. Kuo, MD MSc, FRCPC, Eduard J van Beers, Janet L Kwiatkowski, Bruce A Silver, Elizabeth Merica, Charles Kung, Marvin Cohen, Hua Yang, Jeffrey Hixon, Penelope A Kosinski, Lee Silverman, Lenny Dang, Zheng (Jason) Yuan, Ann J Barbier, Bertil Glader
Journal: Blood
Blood (2016) 128 (22): 402.
https://doi.org/10.1182/blood.V128.22.402.402
Published: 2016
Journal Articles

DRIVE PK: A Phase 2 Trial of AG-348 in Patients with Pyruvate Kinase Deficiency

Ann Barbier, Bruce Silver, Elizabeth Merica, Marvin Cohen, Charles Kung, Hua Yang, PhD, Rachael F. Grace, MD, Bertil Glader, MD PhD, Sam Agresta, MD
Journal: Blood
Blood (2015) 126 (23): 4548.
https://doi.org/10.1182/blood.V126.23.4548.4548
Published: 2015