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Ann J Barbier
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Journal Articles

Effects of AG-348, a Pyruvate Kinase Activator, on Anemia and Hemolysis in Patients with Pyruvate Kinase Deficiency: Data from the DRIVE PK Study

Rachael F Grace, MD, Christian Rose, D Mark Layton, Hassan M Yaish, Wilma Barcellini, Frédéric Galactéros, D Holmes Morton, Yaddanapudi Ravindranath, Kevin H.M. Kuo, MD MSc, FRCPC, Eduard J van Beers, Janet L Kwiatkowski, Bruce A Silver, Elizabeth Merica, Charles Kung, Marvin Cohen, Hua Yang, Jeffrey Hixon, Penelope A Kosinski, Lee Silverman, Lenny Dang, Zheng (Jason) Yuan, Ann J Barbier, Bertil Glader
Journal: Blood
Blood (2016) 128 (22): 402.
https://doi.org/10.1182/blood.V128.22.402.402
Published: 2016
Journal Articles

Population Pharmacokinetics and Pharmacodynamics of AG-519, a Pyruvate Kinase Activator for the Treatment of Pyruvate Kinase Deficiency, in Human Healthy Volunteers

Kha Le, Marvin Cohen, Ann J Barbier, Elizabeth Merica, Charles Kung, Penelope A Kosinski, Scott Biller, Hua Yang
Journal: Blood
Blood (2016) 128 (22): 1263.
https://doi.org/10.1182/blood.V128.22.1263.1263
Published: 2016
Journal Articles

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of AG-519, an Allosteric Activator of Pyruvate Kinase-R, in Healthy Subjects

Ann J Barbier, Susan Bodie, Gary Connor, Elizabeth Merica, Charles Kung, Kha Le, Hua Yang, Penelope A Kosinski, Lee Silverman, Zheng (Jason) Yuan, Chris Bowden, Marvin Cohen
Journal: Blood
Blood (2016) 128 (22): 1264.
https://doi.org/10.1182/blood.V128.22.1264.1264
Published: 2016
Journal Articles

Characterization of Metabolic Response to AG-348, an Allosteric Activator of Red Cell Pyruvate Kinase, in Healthy Volunteers and Pyruvate Kinase Deficiency Patients

Victor Chubukov, Kendall Johnson, Penelope A Kosinski, Michelle Clasquin, Abhishek Jha, Hyeryun Kim, Thomas P Roddy, Elizabeth Merica, Ann J Barbier, Lenny Dang, Lee Silverman, Charles Kung
Journal: Blood
Blood (2016) 128 (22): 2452.
https://doi.org/10.1182/blood.V128.22.2452.2452
Published: 2016