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Journal Articles

Transcutaneous Immunization with a Solid Nanoscopic Imiquimod Suspension Enhances Tumor Rejection

Pamela Stein, PhD, Karsten Gogoll, PhD, Tanja Peters, PhD, Mark Denny, Stefan Tenzer, PhD, Stefan Stevanovic, PhD, Hansjoerg Schild, PhD Prof., Matthias Theobald, MD PhD, Peter Langguth, Markus Radsak, MD

Blood (2015) 126 (23): 2224.

https://doi.org/10.1182/blood.V126.23.2224.2224

Published: 2015

Journal Articles

Granzyme B Is a Key Regulator of Plasmacytoid Dendritic Cell Immunogenicity

Bernd Jahrsdörfer, MD, Thamara Beyer, Hubert Schrezenmeier, MD, Klaus-Michael Debatin, MD, Dorit Fabricius, MD

Blood (2014) 124 (21): 4127.

https://doi.org/10.1182/blood.V124.21.4127.4127

Published: 2014

Journal Articles

Ibrutinib Inhibits Concomitant TLR and BCR- Driven Proliferation of Chronic Lymphocytic Leukemia Cells and Overrides the Supportive Survival-Promoting Effects of Microenvironmental Signals

Sonal Temburni, MS, Jacqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Betty Y. Chang, Nicholas Chiorazzi, MD, Rajendra N Damle, PhD

Blood (2014) 124 (21): 3310.

https://doi.org/10.1182/blood.V124.21.3310.3310

Published: 2014

Journal Articles

TLR7 Ligand Potentiates GM-CSF-Initiated Antitumor Immunity Through Activation Of Plasmacytoid Dendritic Cells

Megumi Narusawa, Hiroyuki Inoue, MD, PhD, Chika Sakamoto, Yumiko Matsumura, DVM PhD, Atsushi Takahashi, MD, PhD, Ayumi Watanabe, Tomoko Inoue, PhD, Shohei Miyamoto, Koichi Takayama, MD, PhD, Makoto Inoue, PhD, Mamoru Hasegawa, PhD, Yoichi Nakanishi, MD, PhD, Kenzaburo Tani, MD, PhD

Blood (2013) 122 (21): 4491.

https://doi.org/10.1182/blood.V122.21.4491.4491

Published: 2013

Journal Articles

Differential Effects Of Triggering Via Toll Like Receptors In Stable Or Aggressive Chronic Lymphocytic Leukemia

Min Chen, MD, PhD, Claude Capron, PharmD, PhD, Gilbert Faure, MD, PhD, Marc Maynadie, MD, PhD, Pierre Feugier, MD, PhD, Marcelo de Carvalho Bittencourt, MD, PhD, Marie C Béné, PharmSciD, PhD

Blood (2013) 122 (21): 5296.

https://doi.org/10.1182/blood.V122.21.5296.5296

Published: 2013

Journal Articles

CT Antigen-Specific Immune Response From DAC/DC Vaccine Correlates With Clinical Outcome In Patients With Relapsed Neuroblastoma

Deepa Kolaseri Krishnadas, PhD, Fanqi Bai, MD, Kenneth Lucas

Blood (2013) 122 (21): 2023.

https://doi.org/10.1182/blood.V122.21.2023.2023

Published: 2013

Journal Articles

The Mir17∼92 Cluster Is an Immunomodulator in CLL Regulating Distinct Functional Responses to Toll-Like Receptors in Subsets with Stereotyped Antigen Receptors

Stavroula Ntoufa, Nikos Papakonstantinou, Christos Nikolaou, Elisavet Chartomatzidou, Tasoula Touloumenidou, Achilles Anagnostopoulos, Marta Muzio, Paolo Ghia, Chrysoula Belessi, Kostas Stamatopoulos

Blood (2012) 120 (21): 3862.

https://doi.org/10.1182/blood.V120.21.3862.3862

Published: 2012

Journal Articles

FcμR (TOSO/ FAIM3 ) Is An O-Glycosylated Endocytic Receptor That Shuttles IgM From the Cell Surface to the Lysosome and Whose Expression Is Regulated by TLR Signaling

Berengere Vire, Ph.D., Alexandre David, Ph.D., Adrian Wiestner, MD, PhD

Blood (2011) 118 (21): 2828.

https://doi.org/10.1182/blood.V118.21.2828.2828

Published: 2011

Journal Articles

CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues

Vanja Sisirak, Nelly Vey, Béatrice Vanbervliet, Thomas Duhen, Isabelle Puisieux, Bernhard Homey, Edward P. Bowman, Giorgio Trinchieri, Bertrand Dubois, Dominique Kaiserlian, Sergio A. Lira, Alain Puisieux, Jean-Yves Blay, Christophe Caux, Nathalie Bendriss-Vermare

Blood (2011) 118 (19): 5130–5140.

https://doi.org/10.1182/blood-2010-07-295626

Published: 2011

Includes: Supplemental data

Journal Articles

Differential Functional Outcomes After Stimulation Via Innate Immunity Receptors In Chronic Lymphocytic Leukemia Subtypes Defined by the Molecular Features of the Immunoglobulin Receptor

Stavroula Ntoufa, Anna Vardi, Nikos Papakonstantinou, Achilles Anagnostopoulos, Vassiliki Aleporou-Marinou, Federico Caligaris-Cappio, M.D., Chrysoula Belessi, Paolo Ghia, Marta Muzio, Kostas Stamatopoulos

Blood (2010) 116 (21): 374.

https://doi.org/10.1182/blood.V116.21.374.374

Published: 2010

Journal Articles

Stimulation of B-CLL Cells with Interleukin 21 and Toll Like Receptor Agonists Induces a CTL-Like Transcriptional Profile.

Magdalena Hagn, MD, Verena Ebel, Kai Sontheimer, Thamara Beyer, Sue E. Blackwell, Thomas Simmet, MD, George J. Weiner, MD, Bernd Jahrsdoerfer, MD

Blood (2009) 114 (22): 3685.

https://doi.org/10.1182/blood.V114.22.3685.3685

Published: 2009

Journal Articles

Toll-Like Receptor-7 Agonist Directly Inhibits the Growth and Induces Apoptosis of MLL-AF9 Leukemia Cells in Vitro and in Vivo

Xueqing Liang, MD, PhD, Ashish Kumar, MBBS, PhD, Zhimei Wang, MD, Brenda Weigel, MSc, MD, Bruce R Blazar, M.D., Wei Chen, MD, PhD

Blood (2008) 112 (11): 2989.

https://doi.org/10.1182/blood.V112.11.2989.2989

Published: 2008

Journal Articles

EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I–associated adult T-cell leukemia/lymphoma

Georges Moarbess, Hiba El-Hajj, Youmna Kfoury, Marwan E. El-Sabban, Yves Lepelletier, Olivier Hermine, Carine Deleuze-Masquéfa, Pierre-Antoine Bonnet, Ali Bazarbachi

Blood (2008) 111 (7): 3770–3777.

https://doi.org/10.1182/blood-2007-11-121913

Published: 2008

Journal Articles

Toll-Like Receptor Agonists Induce Immunogeneicity and Apoptosis of Acute Myeloid Leukemia Cells.

Maki Shindo, MD, PhD, Xueqing Liang, MD PhD, Zhimei Wang, MD, Jeffery S. Miller, MD, Martin Carroll, MD, Wei Chen, MD PhD

Blood (2007) 110 (11): 160.

https://doi.org/10.1182/blood.V110.11.160.160

Published: 2007

Journal Articles

Activation of Integrin αIIbβ3 through Toll-Like Receptors in Platelets.

Jun Yamanouchi, MD, PhD, Jun An, MD, Hiroshi Fujiwara, MD, PhD, Yoshihiro Yakushijin, MD, PhD, Takaaki Hato, MD, PhD, Masaki Yasukawa, MD, PhD

Blood (2007) 110 (11): 3892.

https://doi.org/10.1182/blood.V110.11.3892.3892

Published: 2007

Journal Articles

Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice

Valeska Heib, Marc Becker, Tobias Warger, Gerd Rechtsteiner, Christine Tertilt, Matthias Klein, Tobias Bopp, Christian Taube, Hansjörg Schild, Edgar Schmitt, Michael Stassen

Blood (2007) 110 (3): 946–953.

https://doi.org/10.1182/blood-2006-07-036889

Published: 2007

Journal Articles

Toll-Like Receptor 7-Targeting of Human B-Lineage Acute Lymphocytic Leukemia Induces Immunogeneicity and Apoptosis of Leukemia Cells.

Xueqing Liang, MD, PhD, Jakub Tolar, MD, PhD, Jeffery S. Miller, MD, Tucker W. LeBien, PhD, Bruce R. Blazar, MD, Wei Chen, MD, PhD

Blood (2006) 108 (11): 706.

https://doi.org/10.1182/blood.V108.11.706.706

Published: 2006

Journal Articles

Characterization of Vaccine Site and Cellular Infiltrate in Subjects with Chronic Myeloid Leukemia (CML) Receiving K562/GM-CSF Vaccination in Combination with Imatinib Mesylate with or without Topical Imiquimod.

Christina Y. Chia, MD, B. Douglas Smith, MD, Yvette Kasamon, MD, Carole B. Miller, MD, Mary E. Brummet, MS, Lora Bankova, MD, Jeanne Kowalski, PhD, Barbara Biedrzycki, MSN, Kristen Hege, Lisa A. Beck, MD, Hyam Levitsky, MD

Blood (2005) 106 (11): 2399.

https://doi.org/10.1182/blood.V106.11.2399.2399

Published: 2005

Journal Articles

K562/GM-CSF Vaccination Reduces Tumor Burden, Including Achieving Molecular Remissions, in Chronic Myeloid Leukemia (CML) Patients with Residual Disease on Imatinib Mesylate (IM).

B. Douglas Smith, MD, Yvette L. Kasamon, MD, Carole B. Miller, MD, Christina Chia, MD, Kathleen Murphy, PhD, Jeanne Kowalski, PhD, Irena Tartakovsky, MS, Barbara Biedrzycki, AOCN/CRNP, Richard J. Jones, MD, Kristen Hege, MD, Hyam I. Levitsky, MD

Blood (2005) 106 (11): 2858.

https://doi.org/10.1182/blood.V106.11.2858.2858

Published: 2005

Journal Articles

Discovery of novel immunostimulants by dendritic-cell–based functional screening

Norikatsu Mizumoto, Jimin Gao, Hironori Matsushima, Yasushi Ogawa, Hiroaki Tanaka, Akira Takashima

Blood (2005) 106 (9): 3082–3089.

https://doi.org/10.1182/blood-2005-03-1161

Published: 2005

NARROW

Transcutaneous Immunization with a Solid Nanoscopic Imiquimod Suspension Enhances Tumor Rejection

Granzyme B Is a Key Regulator of Plasmacytoid Dendritic Cell Immunogenicity

Ibrutinib Inhibits Concomitant TLR and BCR- Driven Proliferation of Chronic Lymphocytic Leukemia Cells and Overrides the Supportive Survival-Promoting Effects of Microenvironmental Signals

TLR7 Ligand Potentiates GM-CSF-Initiated Antitumor Immunity Through Activation Of Plasmacytoid Dendritic Cells

Differential Effects Of Triggering Via Toll Like Receptors In Stable Or Aggressive Chronic Lymphocytic Leukemia

CT Antigen-Specific Immune Response From DAC/DC Vaccine Correlates With Clinical Outcome In Patients With Relapsed Neuroblastoma

The Mir17∼92 Cluster Is an Immunomodulator in CLL Regulating Distinct Functional Responses to Toll-Like Receptors in Subsets with Stereotyped Antigen Receptors

FcμR (TOSO/ FAIM3 ) Is An O-Glycosylated Endocytic Receptor That Shuttles IgM From the Cell Surface to the Lysosome and Whose Expression Is Regulated by TLR Signaling

CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues

Differential Functional Outcomes After Stimulation Via Innate Immunity Receptors In Chronic Lymphocytic Leukemia Subtypes Defined by the Molecular Features of the Immunoglobulin Receptor

Stimulation of B-CLL Cells with Interleukin 21 and Toll Like Receptor Agonists Induces a CTL-Like Transcriptional Profile.

Toll-Like Receptor-7 Agonist Directly Inhibits the Growth and Induces Apoptosis of MLL-AF9 Leukemia Cells in Vitro and in Vivo

EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I–associated adult T-cell leukemia/lymphoma

Toll-Like Receptor Agonists Induce Immunogeneicity and Apoptosis of Acute Myeloid Leukemia Cells.

Activation of Integrin αIIbβ3 through Toll-Like Receptors in Platelets.

Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice

Toll-Like Receptor 7-Targeting of Human B-Lineage Acute Lymphocytic Leukemia Induces Immunogeneicity and Apoptosis of Leukemia Cells.

Characterization of Vaccine Site and Cellular Infiltrate in Subjects with Chronic Myeloid Leukemia (CML) Receiving K562/GM-CSF Vaccination in Combination with Imatinib Mesylate with or without Topical Imiquimod.

K562/GM-CSF Vaccination Reduces Tumor Burden, Including Achieving Molecular Remissions, in Chronic Myeloid Leukemia (CML) Patients with Residual Disease on Imatinib Mesylate (IM).

Discovery of novel immunostimulants by dendritic-cell–based functional screening

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American Society of Hematology

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American Society of Hematology

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