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Journal Articles

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML

Sagarajit Mohanty, MSc, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Basem Othman, Arnold Kloos, PhD, Madhvi Mandhania, MSc, Renate Schottmann, Euan Ramsay, PhD, Hans- Peter Vornlocher, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2545.
https://doi.org/10.1182/blood-2019-123709
Published: 2019
Journal Articles

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery

Elie Haddad, Brent R. Logan, Linda M. Griffith, Rebecca H. Buckley, Roberta E. Parrott, Susan E. Prockop, Trudy N. Small, Jessica Chaisson, Christopher C. Dvorak, Megan Murnane, Neena Kapoor, Hisham Abdel-Azim, Imelda C. Hanson, Caridad Martinez, Jack J. H. Bleesing, Sharat Chandra, Angela R. Smith, Matthew E. Cavanaugh, Soma Jyonouchi, Kathleen E. Sullivan, Lauri Burroughs, Suzanne Skoda-Smith, Ann E. Haight, Audrey G. Tumlin, Troy C. Quigg, Candace Taylor, Blachy J. Dávila Saldaña, Michael D. Keller, Christine M. Seroogy, Kenneth B. Desantes, Aleksandra Petrovic, Jennifer W. Leiding, David C. Shyr, Hélène Decaluwe, Pierre Teira, Alfred P. Gillio, Alan P. Knutsen, Theodore B. Moore, Morris Kletzel, John A. Craddock, Victor Aquino, Jeffrey H. Davis, Lolie C. Yu, Geoffrey D. E. Cuvelier, Jeffrey J. Bednarski, Frederick D. Goldman, Elizabeth M. Kang, Evan Shereck, Matthew H. Porteus, James A. Connelly, Thomas A. Fleisher, Harry L. Malech, William T. Shearer, Paul Szabolcs, Monica S. Thakar, Mark T. Vander Lugt, Jennifer Heimall, Ziyan Yin, Michael A. Pulsipher, Sung-Yun Pai, Donald B. Kohn, Jennifer M. Puck, Morton J. Cowan, Richard J. O'Reilly, Luigi D. Notarangelo
Journal: Blood
Blood (2018) 132 (17): 1737–1749.
https://doi.org/10.1182/blood-2018-03-840702
Published: 2018
Includes: Supplemental data
Journal Articles

B-cell differentiation and IL-21 response in IL2RG/JAK3 SCID patients after hematopoietic stem cell transplantation

Clinical Trials & Observations
Alexandra M. Miggelbrink, Brent R. Logan, Rebecca H. Buckley, Roberta E. Parrott, Christopher C. Dvorak, Neena Kapoor, Hisham Abdel-Azim, Susan E. Prockop, David Shyr, Hélène Decaluwe, Imelda C. Hanson, Alfred Gillio, Blachy J. Dávila Saldaña, Hermann Eibel, Gregory Hopkins, Jolan E. Walter, Jennifer S. Whangbo, Donald B. Kohn, Jennifer M. Puck, Morton J. Cowan, Linda M. Griffith, Elie Haddad, Richard J. O’Reilly, Luigi D. Notarangelo, Sung-Yun Pai
Journal: Blood
Blood (2018) 131 (26): 2967–2977.
https://doi.org/10.1182/blood-2017-10-809822
Published: 2018
Includes: Supplemental data
Journal Articles

Decitabine enhances targeting of AML cells by CD34 + progenitor-derived NK cells in NOD/SCID/IL2Rg null mice

Jeannette Cany, Mieke W. H. Roeven, Janneke S. Hoogstad-van Evert, Willemijn Hobo, Frans Maas, Rosalia Franco Fernandez, Nicole M. A. Blijlevens, Walter J. van der Velden, Gerwin Huls, Joop H. Jansen, Nicolaas P. M. Schaap, Harry Dolstra
Journal: Blood
Blood (2018) 131 (2): 202–214.
https://doi.org/10.1182/blood-2017-06-790204
Published: 2018
Includes: Supplemental data
Journal Articles

The Novel Calcium Release-Activated Calcium (CRAC) Channel Inhibitor RP4010 Exerts Potent Antitumor Effects in NOD/SCID/IL2Rg -/- Mice with Diffuse Large B Cell Lymphoma (DLBCL) Cell Line Xenografts

Silvia Laura Locatelli, PhD, Giuseppa Careddu, Massimo Magagnoli, MD, Martina di Trani, Lucia Morello, MD, Srikant Viswanadha, PhD, Swaroop Kumar VS Vakkalanka, PhD, Luca Castagna, MD, Armando Santoro, MD, Carmelo Carlo-Stella, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4101.
https://doi.org/10.1182/blood.V130.Suppl_1.4101.4101
Published: 2017
Journal Articles

Comparison of Induction Chemotherapy in NSG and NOD- Rag1 null IL2rg null Mouse Models of FLT3 Mutant AML

Hong Mu, MD PhD, Marina Konopleva, MD PhD, Rodrigo Jacamo, PhD, Bing Z Carter, PhD, Teresa McQueen, MS, Michael Andreeff, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2692.
https://doi.org/10.1182/blood.V130.Suppl_1.2692.2692
Published: 2017
Journal Articles

Improving transplantation for IL2RG/JAK3 SCID

Michael D. Keller
Journal: Blood
Blood (2017) 129 (15): 2049–2050.
https://doi.org/10.1182/blood-2017-03-770974
Published: 2017
Journal Articles

Long-term outcome of hematopoietic stem cell transplantation for IL2RG/JAK3 SCID: a cohort report

Brief Report
Intan Juliana Abd Hamid, Mary A. Slatter, Fiona McKendrick, Mark S. Pearce, Andrew R. Gennery
Journal: Blood
Blood (2017) 129 (15): 2198–2201.
https://doi.org/10.1182/blood-2016-11-748616
Published: 2017
Includes: Supplemental data
Journal Articles

Investigating the Effects of Anti-CD200 Therapy for Childhood ALL

Paraskevi Diamanti, BSc, PhD, Charlotte V. Cox, BSc, Benjamin C Ede, BSc, Penka S. Petrova, PhD, Robert A. Uger, PhD, Allison Blair, PhD BSc
Journal: Blood
Blood (2016) 128 (22): 4021.
https://doi.org/10.1182/blood.V128.22.4021.4021
Published: 2016
Journal Articles

Inhibition of Both Activated p38 Mapkα and mTORC1 Potentiates the Effect of SR1 on Promoting Hematopoietic Reconstitution of E x V ivo Expanded Human Umbilical Cord Blood Hematopoietic Stem Cells

Xiao Ma, Xiaoyi Li, Danyue Peng, Huifang Wang, Lei Li, Hao Zhou, Daohong Zhou, Yi Luo, Lingbo Liu
Journal: Blood
Blood (2016) 128 (22): 2173.
https://doi.org/10.1182/blood.V128.22.2173.2173
Published: 2016
Journal Articles

RSK Inhibition Suppresses AML Proliferation through Activation of DNA Damage Pathways and S Phase Arrest

Ritika Dutta, BS, Maria Castellanos, MD, Bruce Tiu, Hee-Don Chae, PhD, Kara L. Davis, DO, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2894.
https://doi.org/10.1182/blood.V128.22.2894.2894
Published: 2016
Journal Articles

A Whole Genome In Vivo Crispr Screen in Primary ALL Predicts Leukaemic Relapse

Katherine Dormon, MSci, Elda S Latif, PhD, Matthew Bashton, PhD, Deepali Pal, PhD, Matthew Selby, MSci, Helen Blair, PhD, Vikki Rand, PhD, Andrew G Hall, PhD, Josef Vormoor, MD FRCPCH, Olaf Heidenreich, PhD
Journal: Blood
Blood (2015) 126 (23): 2619.
https://doi.org/10.1182/blood.V126.23.2619.2619
Published: 2015
Journal Articles

Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD

Anne-Kathrin Hechinger, Benjamin A. H. Smith, Ryan Flynn, Kathrin Hanke, Cameron McDonald-Hyman, Patricia A. Taylor, Dietmar Pfeifer, Björn Hackanson, Franziska Leonhardt, Gabriele Prinz, Heide Dierbach, Annette Schmitt-Graeff, Jiri Kovarik, Bruce R. Blazar, Robert Zeiser
Journal: Blood
Blood (2015) 125 (3): 570–580.
https://doi.org/10.1182/blood-2014-06-581793
Published: 2015
Includes: Supplemental data
Journal Articles

CD43 but Not CD41 Marks the First Hematopoietic Stem Cells in the Human Embryo

Andrejs Ivanovs, MD PhD, Stanislav Rybtsov, PhD, Richard A. Anderson, MB ChB, PhD, Alexander Medvinsky, PhD
Journal: Blood
Blood (2014) 124 (21): 4330.
https://doi.org/10.1182/blood.V124.21.4330.4330
Published: 2014
Journal Articles

Kit Deficiency Regulates Stable Human Hematopoietic Stem Cell Engraftment in Mice

Claudia Waskow, PhD, Susann Rahmig, Nehir Cosgun
Journal: Blood
Blood (2014) 124 (21): 653.
https://doi.org/10.1182/blood.V124.21.653.653
Published: 2014
Journal Articles

Cohesin Genes Are Negative Regulators of HSC Renewal

Roman Galeev, PhDstudent, Aurelie Baudet, PhD, Anders Kvist, PhD, Therese Törngren, PhDstudent, Shamit Soneji, PhD, Åke Borg, PhD, Jonas Larsson, MD PhD
Journal: Blood
Blood (2014) 124 (21): 605.
https://doi.org/10.1182/blood.V124.21.605.605
Published: 2014
Journal Articles

Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia

Mark J. Kiel, Thirunavukkarasu Velusamy, Delphine Rolland, Anagh A. Sahasrabuddhe, Fuzon Chung, Nathanael G. Bailey, Alexandra Schrader, Bo Li, Jun Z. Li, Ayse B. Ozel, Bryan L. Betz, Roberto N. Miranda, L. Jeffrey Medeiros, Lili Zhao, Marco Herling, Megan S. Lim, Kojo S. J. Elenitoba-Johnson
Journal: Blood
Blood (2014) 124 (9): 1460–1472.
https://doi.org/10.1182/blood-2014-03-559542
Published: 2014
Includes: Supplemental data
Journal Articles

Influence Of DNA Methyltransferese Inhibitors On The Anti-Leukemic Effect Of Umbilical Cord Blood Derived NK Cells Against Acute Myeloid Leukemia

Harry Dolstra, PhD, Jeannette Cany, PhD, Anniek B. van der Waart, MSc, Marleen Tordoir, BSc, Basav Nagaraj Hangalapura, PhD, Jan Spanholtz, PhD, Robbert van der Voort, PhD, Nicolaas PM Schaap, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4496.
https://doi.org/10.1182/blood.V122.21.4496.4496
Published: 2013
Journal Articles

BALB/c- Specific L29V Polymorphism In SIRPA Determines The Efficient Engraftment Of Human Hematopoiesis In Xenogeneic Model

Chika Iwamoto, Katsuto Takenaka, MD, PhD, Shingo Urata, MD, Takahiro Shima, MD, Takuji Yamauchi, MD, PhD, Takuro Kuriyama, MD, PhD, Shinya Daitoku, MD, Yasuyuki Saito, MD, PhD, Katsuhiko Itoh, MD, PhD, Junji Kishimoto, PhD, Daisuke Kohda, PhD, Takashi Matozaki, MD, PhD, Koichi Akashi, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 337.
https://doi.org/10.1182/blood.V122.21.337.337
Published: 2013
Journal Articles

Parallel Transcriptional Analysis of Multiple Stem and Progenitor Populations Identifies Novel Commonly Dysregulated and Functionally Relevant Targets in AML

Laura Barreyro, Britta Will, PhD, Boris Bartholdy, Ph.D., Li Zhou, PhD, Tihomira I Todorova, B.A., Robert Stanley, Susana Ben-Neriah, Cristina Montagna, PhD, Samir Parekh, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Elisabeth Paietta, PhD, Rhett P Ketterling, MD, Larry D Cripe, MD, Hugo F Fernandez, MD, Peter L. Greenberg, MD, Jacob M Rowe, MD, Martin S. Tallman, MD, Christian Steidl, MD, Constantine S. Mitsiades, MD, PhD, Amit Verma, MD, Ulrich Steidl, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 1875.
https://doi.org/10.1182/blood.V120.21.1875.1875
Published: 2012