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Journal Articles

HIF2 keeps paces in tight hypoxic spaces

Sean P. Colgan

Blood (2021) 137 (24): 3323–3324.

https://doi.org/10.1182/blood.2021011009

Published: 2021

Journal Articles

HIF2α is a direct regulator of neutrophil motility

Sundary Sormendi, Mathieu Deygas, Anupam Sinha, Mathilde Bernard, Anja Krüger, Ioannis Kourtzelis, Gregoire Le Lay, Pablo J. Sáez, Michael Gerlach, Kristin Franke, Ana Meneses, Martin Kräter, Alessandra Palladini, Jochen Guck, Ünal Coskun, Triantafyllos Chavakis, Pablo Vargas, Ben Wielockx

Blood (2021) 137 (24): 3416–3427.

https://doi.org/10.1182/blood.2020007505

Published: 2021

Includes: Supplemental data

Journal Articles

Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

Manik C. Ghosh, De-Liang Zhang, Wade H. Ollivierre, Audrey Noguchi, Danielle A. Springer, W. Marston Linehan, Tracey A. Rouault

Blood (2021) 137 (18): 2509–2519.

https://doi.org/10.1182/blood.2020009138

Published: 2021

Includes: Supplemental data

Journal Articles

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Shinichi Ishii, Tomohide Suzuki, Kanako Wakahashi, Noboru Asada, Yuko Kawano, Hiroki Kawano, Akiko Sada, Kentaro Minagawa, Yukio Nakamura, Seiya Mizuno, Satoru Takahashi, Toshimitsu Matsui, Yoshio Katayama

Blood (2021) 137 (11): 1457–1467.

https://doi.org/10.1182/blood.2020007172

Published: 2021

Includes: Supplemental data

Journal Articles

Sickle marrow: double, double toil and trouble

Mark C. Walters

Blood (2020) 135 (23): 2017–2018.

https://doi.org/10.1182/blood.2020005114

Published: 2020

Journal Articles

Zinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer Results in Enriched Biallelic Editing, Increased Fetal Hemoglobin, and Reduced Sickling in Erythroid Cells Derived from Sickle Cell Disease Patients

Samuel Lessard, PhD, Pauline Rimmele, PhD, Hui Ling, PhD, Kevin Moran, MSc, Benjamin Vieira, BS, Yi-Dong Lin, PhD, Vu Hong, PhD, Andreas Reik, PhD, Denny Dang, Naoya Uchida, MD, John F. Tisdale, MD, Pablo Rendo, MD, Ahmed Daak, PhD, Alexandra Hicks, PhD

Blood (2019) 134 (Supplement_1): 974.

https://doi.org/10.1182/blood-2019-126048

Published: 2019

Journal Articles

Mitophagy Plays a Key Role in the Anti-Leukemic Activity of Autophagy Inhibitors Under Hypoxia in Acute Myeloid Leukemia

Hannah R.S. Fay, BS, Kaitlyn M. Dykstra, PhD, Matthew Johnson, Tara L. Cronin, BA, Linda Lutgen-Dunckley, Brandon L. Martens, BS, Joseph R. Moberg, BS, Monica L. Guzman, PhD, Eunice S. Wang, MD

Blood (2019) 134 (Supplement_1): 1278.

https://doi.org/10.1182/blood-2019-127024

Published: 2019

Journal Articles

Nlrp3 Inflammasome Activation in Bone Marrow-Residing Innate Immunity Cells Governs Circadian Changes in the Number of Circulating Hematopoietic Stem/Progenitor Cells in Peripheral Blood

Mateusz Adamiak, PhD, Andrzej Ciechanowicz, PhD, Monika Cymer, MS, Marta Skoda, PhD, Mariusz Z Ratajczak, MD PhD DSc

Blood (2019) 134 (Supplement_1): 1033.

https://doi.org/10.1182/blood-2019-125853

Published: 2019

Journal Articles

Association of Endothelial Biomarkers with Cerebral MRI Perfusion Analysis in Patients with Sickle Cell Disease

Liza Afzali-Hashemi, Lena Vaclavu, PhD, Erfan Nur, MD PhD, Aart J Nederveen, PhD, Bart J. Biemond, MD PhD

Blood (2019) 134 (Supplement_1): 1000.

https://doi.org/10.1182/blood-2019-124688

Published: 2019

Journal Articles

Thrombopoietin Has Protective Effect in Neonatal Hypoxia-Ischemia Rat Model

Liang Li, PhD, Liuming Yang, Hongwu Xin, Beng H Chong, MBBS, PhD, Mo Yang, MD

Blood (2019) 134 (Supplement_1): 4898.

https://doi.org/10.1182/blood-2019-131575

Published: 2019

Journal Articles

A Phase 1 Study of Carfilzomib-Thalidomide-Dexamethasone in Patients with Relapsed/Refractory AL Amyloidosis - Catalyst Trial Results

Mamta Garg, MD FRCP, FRCPath, Andrew Hall, Matthew Jenner, MBBS, MRCP, FRCPath, Bhuvan Kishore, MB BS, MRCP, FRCPath, Helen J Lachmann, MA MB BChir MDFRCP, Julian D Gillmore, MBBS, MD PhD FRCP, Alexandra Pitchford, Louise Flanagan, PhD, Jamie B Oughton, MPhil, BSc, Shameem Mahmood, Sajitha Sachchithanantham, Sarah R Brown, PhD MSc, BSc, Ashutosh D Wechalekar, MBBS, MD FRCP, FRCPath, DM

Blood (2019) 134 (Supplement_1): 1890.

https://doi.org/10.1182/blood-2019-126567

Published: 2019

Journal Articles

Hexokinase-2 Regulates Hypoxia-Inducible Autophagy, Leading to Enhance Anti-Apoptotic Capability of Refractory Multiple Myeloma

Sho Ikeda, MD PhD, Fumito Abe, MD PhD, Matsuda Yuka, Akihiro Kitadate, MD PhD, Takahiro Kobayashi, MD PhD, Naoto Takahashi, MD PhD, Hiroyuki Tagawa, MD PhD

Blood (2019) 134 (Supplement_1): 1787.

https://doi.org/10.1182/blood-2019-123360

Published: 2019

Journal Articles

Two Year Update of Phase II Trial of Pembrolizumab, Lenalidomide and Dexamethasone As Post -Autologous Stem Cell Transplant Consolidation in Patients with High-Risk Multiple Myeloma

Meena Bansal, DO, David S. Siegel, Jaeil Ahn, PhD, Rena Feinman, PhD, David H. Vesole, MD PhD, Joshua R Richter, MD, Andrew L. Pecora, MD, Elli Gourna Paleoudis, PhD, Scott D. Rowley, MD, Michele L. Donato, MD, Robert Korngold, PhD, Palka Anand, RN, BSN, CCRP, Laura McBride, RN, BSN, OCN, Kristin Ivanovski, RN, BSN, CCRP, Noa Biran, MD

Blood (2019) 134 (Supplement_1): 1911.

https://doi.org/10.1182/blood-2019-125155

Published: 2019

Journal Articles

Hematological Changes in Chronic Sustained Hypoxia and Chronic Intermittent Hypoxia in a Mouse Model

Jihyun Song, PhD, Krishna M Sundar, MD, John Hoidal, MD, Josef T. Prchal, MD

Blood (2019) 134 (Supplement_1): 3525.

https://doi.org/10.1182/blood-2019-131309

Published: 2019

Journal Articles

Erythropoietin Downregulates Red Blood Cell Clearance in Mice

Martin Colard, MD, Michaël Dussiot, PhD, Anaïs Martinez, Carole Peyssonnaux, PhD, Patrick Mayeux, PhD, Fleur Samantha Benghiat, MD PhD, Pierre Buffet, MD PhD, Olivier Hermine, MD PhD, Pascal Amireault, PhD

Blood (2019) 134 (Supplement_1): 3524.

https://doi.org/10.1182/blood-2019-126768

Published: 2019

Journal Articles

Deletion of TLR4 in Townes SS Mice Prevents Microvascular Stasis in Response to Hemin, LPS and Hypoxia/Reoxygenation: Role of Inflammation

John D Belcher, PhD, Fuad Abdulla, Chunsheng Chen, Ping Zhang, PhD, Dormarie Rivera-Rodriguez, Rachel Kirchner, Julia Nguyen, Zachary Monroe Kiser, BS, PhD, Kristine Nachbor, Jacob Lloyd, MD, Gregory M Vercellotti, MD

Blood (2019) 134 (Supplement_1): 3555.

https://doi.org/10.1182/blood-2019-127114

Published: 2019

Journal Articles

Characterization of a Genetically Engineered HUDEP2 Cell Line Harboring a Sickle Cell Disease Mutation As a Potential Research Tool for Preclinical Sickle Cell Disease Drug Discovery

Dipti Gupta, Sarah Sturtevant, BSc, Benjamin Vieira, BS, Yukio Nakamura, MD PhD, Sriram Krishnamoorthy, PhD, Melanie Demers, PhD

Blood (2019) 134 (Supplement_1): 3559.

https://doi.org/10.1182/blood-2019-127330

Published: 2019

Journal Articles

The Effect of the Soluble Guanylate Cyclase Stimulator Olinciguat on Renal Function and Biomarkers of Inflammation and Renal Injury in Sickle Cell Mice

Boris Tchernychev, PhD, Raghunath Ramanarasimhaiah, MD, Guang Liu, PhD, Katherine Hall, PhD, Regina Margaret Graul, PhD, Jaime Masferrer, PhD

Blood (2019) 134 (Supplement_1): 3554.

https://doi.org/10.1182/blood-2019-127361

Published: 2019

Journal Articles

Plasma BDNF Levels Are Associated with Stroke in Children with SCD

Julia A. Drexelius, Celeste K. Kanne, BA, Huy D Tran, MD, Hyacinth I Hyacinth, MDPhDMPH, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 3565.

https://doi.org/10.1182/blood-2019-131191

Published: 2019

Journal Articles

Association between Sensorineural Hearing Loss and Homozygous Sickle Cell Anemia: A Meta-Analysis

Zachary Monroe Kiser, BS, PhD, Kristen A Clark, BA, Jane L Sumner, PhD, Gregory M Vercellotti, MD, M.Dawn Nelson, PhD

Blood (2019) 134 (Supplement_1): 3453.

https://doi.org/10.1182/blood-2019-127740

Published: 2019

NARROW

HIF2 keeps paces in tight hypoxic spaces

HIF2α is a direct regulator of neutrophil motility

Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Sickle marrow: double, double toil and trouble

Zinc Finger Nuclease-Mediated Disruption of the BCL11A Erythroid Enhancer Results in Enriched Biallelic Editing, Increased Fetal Hemoglobin, and Reduced Sickling in Erythroid Cells Derived from Sickle Cell Disease Patients

Mitophagy Plays a Key Role in the Anti-Leukemic Activity of Autophagy Inhibitors Under Hypoxia in Acute Myeloid Leukemia

Nlrp3 Inflammasome Activation in Bone Marrow-Residing Innate Immunity Cells Governs Circadian Changes in the Number of Circulating Hematopoietic Stem/Progenitor Cells in Peripheral Blood

Association of Endothelial Biomarkers with Cerebral MRI Perfusion Analysis in Patients with Sickle Cell Disease

Thrombopoietin Has Protective Effect in Neonatal Hypoxia-Ischemia Rat Model

A Phase 1 Study of Carfilzomib-Thalidomide-Dexamethasone in Patients with Relapsed/Refractory AL Amyloidosis - Catalyst Trial Results

Hexokinase-2 Regulates Hypoxia-Inducible Autophagy, Leading to Enhance Anti-Apoptotic Capability of Refractory Multiple Myeloma

Two Year Update of Phase II Trial of Pembrolizumab, Lenalidomide and Dexamethasone As Post -Autologous Stem Cell Transplant Consolidation in Patients with High-Risk Multiple Myeloma

Hematological Changes in Chronic Sustained Hypoxia and Chronic Intermittent Hypoxia in a Mouse Model

Erythropoietin Downregulates Red Blood Cell Clearance in Mice

Deletion of TLR4 in Townes SS Mice Prevents Microvascular Stasis in Response to Hemin, LPS and Hypoxia/Reoxygenation: Role of Inflammation

Characterization of a Genetically Engineered HUDEP2 Cell Line Harboring a Sickle Cell Disease Mutation As a Potential Research Tool for Preclinical Sickle Cell Disease Drug Discovery

The Effect of the Soluble Guanylate Cyclase Stimulator Olinciguat on Renal Function and Biomarkers of Inflammation and Renal Injury in Sickle Cell Mice

Plasma BDNF Levels Are Associated with Stroke in Children with SCD

Association between Sensorineural Hearing Loss and Homozygous Sickle Cell Anemia: A Meta-Analysis

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American Society of Hematology

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American Society of Hematology

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