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Journal Articles

Hyaluronan Expressed by Bone Marrow Mesenchymal Cells Regulates Functions of the Hematopoietic Microenvironment

Valentina Goncharova, MS, Ingrid U Schraufstaetter, MD, Shinji Iizuka, PhD, Yu Yamaguchi, PhD, Sophia K Khaldoyanidi, MD, PhD

Blood (2012) 120 (21): 1243.

https://doi.org/10.1182/blood.V120.21.1243.1243

Published: 2012

Journal Articles

Functional and Familial Risk of B Lineage Malignancies in Patients Carrying Single Nucleotide Polymorphisms (SNPs) in the Hyaluronan Synthase 1 Gene (HAS1),

Linda M. Pilarski, PhD, Hemalatha Kuppusamy, Jitra Kriangkum, PhD, Amanda Warkentin, Sunita Ghosh, PhD, Spencer B Gibson, PhD, Hlif Steingrimsdottir, MD, Vilhelmina Haraldsdottir, MD, James B Johnston, MD, FRCPC, Helga M Ogmundsdottir, MD, PhD, Andrew R Belch, MD

Blood (2011) 118 (21): 3930.

https://doi.org/10.1182/blood.V118.21.3930.3930

Published: 2011

Journal Articles

Clinically Significant Aberrant HAS1Vb Splicing of the Hyaluronan Synthase 1 Gene ( HAS1 ) Requires a Combination of Mutations and Deletions in Introns 3 and 4 of HAS1 Minigene,

Jitra Kriangkum, PhD, Andrew R Belch, MD, Linda M. Pilarski, PhD

Blood (2011) 118 (21): 3931.

https://doi.org/10.1182/blood.V118.21.3931.3931

Published: 2011

Journal Articles

Hyaluronan Associated with the Bone Marrow Hematopoietic Microenvironment Is Required for the Recruitment and Retention of Hematopoietic Stem and Progenitor Cells In the Bone Marrow.

Valentina Goncharova, MS, Shinji Iizuka, PhD, Yu Yamaguchi, PhD, Sophia Khaldoyanidi, MD, PhD

Blood (2010) 116 (21): 2593.

https://doi.org/10.1182/blood.V116.21.2593.2593

Published: 2010

Journal Articles

Splicing Mutations in the Hyaluronan Synthase I Gene of Patients with Monoclonal Gammopathy of Undetermined Significance.

Hemalatha Kuppusamy, Amanda Warkentin, Andrew Belch, MD, Linda M. Pilarski, PhD

Blood (2009) 114 (22): 2841.

https://doi.org/10.1182/blood.V114.22.2841.2841

Published: 2009

Journal Articles

Splicing Profile of Human Hyaluronan Synthase 1 (HAS1) Is Altered by Mutagenesis of (A/U)GGG Motifs.

Jitra Kriangkum, PhD, Anirban Ghosh, PhD, Amanda A. Warkentin, BSc, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2009) 114 (22): 2842.

https://doi.org/10.1182/blood.V114.22.2842.2842

Published: 2009

Journal Articles

Inherited and acquired variations in the hyaluronan synthase 1 ( HAS1 ) gene may contribute to disease progression in multiple myeloma and Waldenstrom macroglobulinemia

Sophia Adamia, Amanda A. Reichert, Hemalatha Kuppusamy, Jitra Kriangkum, Anirban Ghosh, Jennifer J. Hodges, Patrick M. Pilarski, Steven P. Treon, Michael J. Mant, Tony Reiman, Andrew R. Belch, Linda M. Pilarski

Blood (2008) 112 (13): 5111–5121.

https://doi.org/10.1182/blood-2008-02-141770

Published: 2008

Includes: Supplemental data

Journal Articles

Germline and Somatic Mutations in the Hyaluronan Synthase–1 (HAS1) Gene May Contribute to Oncogenesis in Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Sophia Adamia, PhD, Amanda Reichert, Anirban Ghosh, Ph.D, Jennifer Hodges, Patrick Pilarski, Steven Treon, MD, Michael J. Mant, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, Ph.D

Blood (2007) 110 (11): 2488.

https://doi.org/10.1182/blood.V110.11.2488.2488

Published: 2007

Journal Articles

Genetic Variations in Genomic HAS1 Direct Aberrant Pre-mRNA Splicing That Generates the Prognostically Significant HAS1Vb Intronic Splice Variant.

Jitra Kriangkum, PhD, Anirban Ghosh, PhD, Brian J. Taylor, PhD, Linda M. Pilarski, PhD

Blood (2007) 110 (11): 2497.

https://doi.org/10.1182/blood.V110.11.2497.2497

Published: 2007

Journal Articles

Single Nucleotide Polymorphisms (SNPs) and Recurrent Mutations in the Hyaluronan Synthase 1 (HAS1) Gene May Predispose to Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Sophia Adamia, Steve Treon, MD, Daniel Santos, MD, Zachary Hunter, Michael J. Mant, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, Ph.D

Blood (2005) 106 (11): 1558.

https://doi.org/10.1182/blood.V106.11.1558.1558

Published: 2005

Journal Articles

Intronic splicing of hyaluronan synthase 1 ( HAS1 ): a biologically relevant indicator of poor outcome in multiple myeloma

Sophia Adamia, Tony Reiman, Mary Crainie, Michael J. Mant, Andrew R. Belch, Linda M. Pilarski

Blood (2005) 105 (12): 4836–4844.

https://doi.org/10.1182/blood-2004-10-3825

Published: 2005

Journal Articles

Biochemical Characterization and Gene Expression Profiling of Cytarabine Treated Stromal Fibroblasts Reveal Regulatory Mechanisms Affecting Hyaluronan and Heparan Sulfate Proteoglycans.

Sonja Zweegman, MD, Floortje L. Kessler, Ron Kerkhoven, PhD, Mike Heimerikx, Peter C. Huijgens, MD PhD, Angelika M. Drager, PhD, Jacob van den Born, PhD

Blood (2004) 104 (11): 1304.

https://doi.org/10.1182/blood.V104.11.1304.1304

Published: 2004

Journal Articles

Polymorphisms in the Hyaluronan Synthase 1 Gene May Be Predisposing Factors for Waldenstrom’s Macroglobulinemia.

Sophia Adamia, Steven P. Treon, MD, Michael J. Mant, MD, Loree M. Larratt, MD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2004) 104 (11): 1363.

https://doi.org/10.1182/blood.V104.11.1363.1363

Published: 2004

Journal Articles

Aberrant Intronic Splicing of the Hyaluronan Synthase 1 Gene (HAS1) in Multiple Myeloma: A Biologically Relevant Marker That Predicts for Poor Survival.

Sophia Adamia, Tony Reiman, MD, Michael J. Mant, MD, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2004) 104 (11): 1413.

https://doi.org/10.1182/blood.V104.11.1413.1413

Published: 2004

Journal Articles

Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients

Anthony Calabro, Martin M. Oken, Vincent C. Hascall, Anna M. Masellis

Blood (2002) 100 (7): 2578–2585.

https://doi.org/10.1182/blood-2002-01-0030

Published: 2002

NARROW

Hyaluronan Expressed by Bone Marrow Mesenchymal Cells Regulates Functions of the Hematopoietic Microenvironment

Functional and Familial Risk of B Lineage Malignancies in Patients Carrying Single Nucleotide Polymorphisms (SNPs) in the Hyaluronan Synthase 1 Gene (HAS1),

Clinically Significant Aberrant HAS1Vb Splicing of the Hyaluronan Synthase 1 Gene ( HAS1 ) Requires a Combination of Mutations and Deletions in Introns 3 and 4 of HAS1 Minigene,

Hyaluronan Associated with the Bone Marrow Hematopoietic Microenvironment Is Required for the Recruitment and Retention of Hematopoietic Stem and Progenitor Cells In the Bone Marrow.

Splicing Mutations in the Hyaluronan Synthase I Gene of Patients with Monoclonal Gammopathy of Undetermined Significance.

Splicing Profile of Human Hyaluronan Synthase 1 (HAS1) Is Altered by Mutagenesis of (A/U)GGG Motifs.

Inherited and acquired variations in the hyaluronan synthase 1 ( HAS1 ) gene may contribute to disease progression in multiple myeloma and Waldenstrom macroglobulinemia

Germline and Somatic Mutations in the Hyaluronan Synthase–1 (HAS1) Gene May Contribute to Oncogenesis in Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Genetic Variations in Genomic HAS1 Direct Aberrant Pre-mRNA Splicing That Generates the Prognostically Significant HAS1Vb Intronic Splice Variant.

Single Nucleotide Polymorphisms (SNPs) and Recurrent Mutations in the Hyaluronan Synthase 1 (HAS1) Gene May Predispose to Multiple Myeloma (MM) and Waldenstrom’s Macroglobulinemia (WM).

Intronic splicing of hyaluronan synthase 1 ( HAS1 ): a biologically relevant indicator of poor outcome in multiple myeloma

Biochemical Characterization and Gene Expression Profiling of Cytarabine Treated Stromal Fibroblasts Reveal Regulatory Mechanisms Affecting Hyaluronan and Heparan Sulfate Proteoglycans.

Polymorphisms in the Hyaluronan Synthase 1 Gene May Be Predisposing Factors for Waldenstrom’s Macroglobulinemia.

Aberrant Intronic Splicing of the Hyaluronan Synthase 1 Gene (HAS1) in Multiple Myeloma: A Biologically Relevant Marker That Predicts for Poor Survival.

Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients

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American Society of Hematology

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American Society of Hematology

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