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Journal Articles

Proteomic Analysis of Mitochondrial Membrane Protein FAM210B in Erythroid Cells

Chie Suzuki, Tohru Fujiwara, MD PhD, Hiroki Shima, Koya Ono, MD, Kei Saito, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Shinichi Fujimaki, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3523.
https://doi.org/10.1182/blood-2019-122618
Published: 2019
Journal Articles

Fto Promotes Extramedullary Progression of Multiple Myeloma By Regulation of HSF1 through m 6 a RNA Methylation

Aoshuang Xu, MD, Jiasi Zhang, MD, Liping Zuo, MD, Jian Xu, PhD, Xuejiao Yin, MD, Qianwen Cheng, MD, Yuyang Zhang, MD, Lei Chen, PhD, Fei Zhao, PhD, Fengjuan Fan, PhD, Yu Hu, Chunyan Sun, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3063.
https://doi.org/10.1182/blood-2019-125635
Published: 2019
Journal Articles

LAM-003, a Novel Oral Heat Shock Protein 90 Inhibitor for Treatment of Acute Myeloid Leukemia, Including Wild-Type and FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Disease

Neil Beeharry, Sean Landrette, PhD, Jeff Grotzke, PhD, Sophia Gayle, PhD, Marylens Hernandez, PhD, Stephanie Halene, MD, Peter R Young, PhD, Langdon L Miller, MD, Tian Xu, PhD, Jonathan Rothberg, PhD, Henri Lichenstein, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2664.
https://doi.org/10.1182/blood-2019-125770
Published: 2019
Journal Articles

Dissecting Heterogeneity of Tumor Cells and Their Microenvironment in Refractory Multiple Myeloma

Stephan M Tirier, PhD, Jan-Philipp Mallm, PhD, Nicola Casiraghi, PhD, Hana Susak, PhD, Nicola Giesen, MD, Alexandra M Poos, PhD, Katharina Bauer, Anja Baumann, Lukas John, MD, Jing Xu, PhD, Lara Klett, MSc, Carsten Müller-Tidow, MD, Benedikt Brors, PhD, Hartmut Goldschmidt, MD, Niels Weinhold, PhD, Oliver Stegle, PhD, Karsten Rippe, PhD, Marc S. Raab, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 571.
https://doi.org/10.1182/blood-2019-128625
Published: 2019
Journal Articles

Inducible Phase Separation of GSK3α As a Mechanism for Asparaginase Resistance in Acute Leukemias

Laura Hinze, Sabine Schreek, Andre Zeug, PhD, Evgeni Ponimaskin, PhD, Roxane Labrosse, MD FRCPC, James Degar, Gabriela Chiosis, PhD, Sung-Yun Pai, MD, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Beat Bornhauser, PhD, Jean-Pierre Bourquin, MD PhD, Martin Stanulla, MD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 169.
https://doi.org/10.1182/blood-2019-126633
Published: 2019
Journal Articles

Infusion of Mesenchymal Stem Cells Combined with Epithelial Progenitor Cells Promotes Injured Intestinal Repairing after Hematopoietic Cell Transplantation

Shengyun Zhu, Huiqi Li, Chaoran Lyu, Jing Liang, Lingyu Zeng, MD,PhD, Kailin Xu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5604.
https://doi.org/10.1182/blood-2019-127584
Published: 2019
Journal Articles

Polymorphisms in Inflammatory Genes Modulate the Occurrence of Clinical Complications in Patients with Sickle Cell Disease

Karina Tozatto-Maio, MD, Robert Girot, MD PhD, Indou Deme Ly, MD, Vanderson Rocha, MD PhD, Ana Cristina Silva Pinto, MD PhD, Ibrahima Diagne, Prof, Yahia Benzerara, Francisco Fernandes, Carla Luana Dinardo, MD PhD, Simone Kashima, PhD, Itaua Leston Araujo, MSc, PhD, Chantal Kenzey, Guilherme Henrique Hencklain Fonseca, MD, Evandra Strazza Rodrigues, PhD, Fernanda Volt, MSc, Luciana Ribeiro Jarduli, PhD, Annalisa Ruggeri, MD, Christina Mary Mariaselvam, PhD, Sandra Fatima Menosi Gualandro, MD PhD, Hanadi Elayoubi, MD, Renato Cunha, MD PhD, Barbara Cappelli, MD, Julia Pavan, PhD, Belinda Pinto Simões, MD PhD, Eliane Gluckman, MD PhD, Ryad Tamouza, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4825.
https://doi.org/10.1182/blood-2019-124218
Published: 2019
Journal Articles

Novel Allosteric Inhibitors of Heat Shock Protein 70 As Agents to Probe Protein Homeostasis and Overcome Proteasome Inhibitor Resistance in Multiple Myeloma

Ian Ferguson, BA, Christine Lam, BA, Margarette C. Mariano, MS, Donghui Wang, BA, Paul Phojanakong, BA, Sami Toumivaara, PhD, Hao Shao, PhD, Byron C Hann, MD PhD, Jason Gestwicki, PhD, Arun P Wiita, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3212.
https://doi.org/10.1182/blood-2018-99-117401
Published: 2018
Journal Articles

Development of a Novel Class of Agents Targeting the RNA-Splicing Machinery in Myeloid Malignancies

Valeria Visconte, PhD, Bartlomiej P. Przychodzen, Vera Adema, PhD, Cassandra M. Hirsch, Allison Noe, Rachel Toth, Christina Snider, BA, Hassan Awada, MD, Amy C Graham, BS, MS, Yvonne Parker, Yuriy Fedorov, Drew Adams, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Tomas Radivoyevitch, Heesun J. Rogers, MD PhD, Kevin R Kelly, MD PhD, Steffan T. Nawrocki, PhD, Jennifer S. Carew, PhD, Daniel Lindner, MD PhD, Richard A Padgett, Mikkael A. Sekeres, MD MS, James G Phillips, PhD, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2018) 132 (Supplement 1): 211.
https://doi.org/10.1182/blood-2018-99-116411
Published: 2018
Journal Articles

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

Margherita Vieri, MSc, Christian Preisinger, Mirle Schemionek, Azam Salimi, John B. Patterson, Afshin Samali, Tim H Brümmendorf, MD, Iris Appelmann, MD, Behzad Kharabi Masouleh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4674.
https://doi.org/10.1182/blood-2018-99-110967
Published: 2018
Journal Articles

Targeting Ras-Signalling Pathway to Strike Hsf1 and Induce Apoptosis in Chronic Lymphocytic Leukemia

Flavia Raggi, Federica Frezzato, PhD, Veronica Martini, PhD MSc, Filippo Severin, PhD MSc, Valentina Trimarco, Emanuele Favero, Andrea Visentin, MD, Monica Facco, Gianpietro Semenzato, Livio Trentin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5533.
https://doi.org/10.1182/blood-2018-99-114616
Published: 2018
Journal Articles

Apavac, a Simple Autologous Vaccination Process (AV) Associated with Clinical Efficacy in 56 Patients (pts) Having Cancer (C) and 11 Pts Having Hematological Malignancies (HM)

Jean-Francois Rossi, MD PhD, Nicole Rouquet, PhD, Patrick Frayssinet, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5690.
https://doi.org/10.1182/blood-2018-99-118862
Published: 2018
Journal Articles

Thermal Ablation of Colorectal Cancer Metastases Leads to Activation of Individual Cancer-Specific T Cell Immunity

Sebastian Haen, MD, Bianca Nussbaum, Daniel Johannes Kowalewski, Guenter Jaeger, Philippe Pereira, Stephan Clasen, Bence Sipos, Ingmar Koenigsrainer, Stefan Beckert, Silvia Wagner, Olaf H. Riess, Alfred Koenigsrainer, Stefan Stevanovic, Lothar Kanz, Hans-Georg Rammensee, Markus W. Loeffler, Cecile Gouttefangeas
Journal: Blood
Blood (2017) 130 (Supplement 1): 2282.
https://doi.org/10.1182/blood.V130.Suppl_1.2282.2282
Published: 2017
Journal Articles

Protein Homeostasis: A Key Target in Myeloma

Lawrence H. Boise, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-8.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-8.SCI-8
Published: 2017
Journal Articles

Proteotoxicity in Cardiac Amyloidosis: Amyloidogenic Light Chains Affect the Levels of Iintracellular Proteins in Human Heart Cells

Esther Imperlini, PhD, Massimiliano Gnecchi, MD PhD, Paola Rognoni, PhD, Eduard Sabidò, PhD, Maria Chiara Ciuffreda, Giovanni Palladini, MDPhD, Guadalupe Espadas, Giuseppina Palladini, Stefania Orrù, PhD, Paolo Milani, MD PhD, Stefano Perlini, MD PhD, Francesco Salvatore, MD PhD, Giampaolo Merlini, MD, Francesca Lavatelli, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4393.
https://doi.org/10.1182/blood.V130.Suppl_1.4393.4393
Published: 2017
Journal Articles

PI3Kδ/AKT Inhibition Augments 2-Phenylethynesulfonamide Induced Apoptosis Via the Unfolded Protein Response in Chronic Lymphocytic Leukemia

Matthew D Blunt, PhD, Lindsay D Smith, PhD, Adam Linley, PhD BSc, Jonathan C Strefford, PhD, Peter Johnson, Francesco Forconi, MD DM, PhD FRCPath, Freda K. Stevenson, DPhil, Graham Packham, PhD, Andrew J Steele, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4290.
https://doi.org/10.1182/blood.V130.Suppl_1.4290.4290
Published: 2017
Journal Articles

The Novel Protein HSF1 Stress Pathway Inhibitor Bisamide CCT361814 Demonstrates Pre-Clinical Anti-Tumor Activity in Myeloma

Karen Menezes, PhD BSc, MSc, Grace Aram, MSc, Fabio Mirabella, PhD, David C Johnson, PhD, Amy L Sherborne, PhD, Richard S Houlston, MD PhD, Matthew D Cheeseman, PhD, Elisa Pasqua, PhD, Paul Clarke, PhD, Paul Workman, PhD, Keith Jones, PhD, Martin F Kaiser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3072.
https://doi.org/10.1182/blood.V130.Suppl_1.3072.3072
Published: 2017
Journal Articles

Enhancement of Allo-NK Cell Activity in Myeloid Leukemia Cell Line KG-1a after Combined with Aclacinomycin

Yongbin Ye, MDPhD, Xiaojun Xu, MDPhD, Yanhong Chen, MM, Mingwan Zhang, MM, Dafa Qiu, MM, Ziwen Guo, MB, Huiqing He, MB
Journal: Blood
Blood (2017) 130 (Supplement 1): 5074.
https://doi.org/10.1182/blood.V130.Suppl_1.5074.5074
Published: 2017
Journal Articles

Unexpected role for p19 INK4d in posttranscriptional regulation of GATA1 and modulation of human terminal erythropoiesis

Xu Han, Jieying Zhang, Yuanliang Peng, Minyuan Peng, Xiao Chen, Huiyong Chen, Jianhui Song, Xiao Hu, Mao Ye, Jianglin Li, Vijay G. Sankaran, Christopher D. Hillyer, Narla Mohandas, Xiuli An, Jing Liu
Journal: Blood
Blood (2017) 129 (2): 226–237.
https://doi.org/10.1182/blood-2016-09-739268
Published: 2017
Includes: Supplemental data
Journal Articles

Identification of Anti-Lymphoma Biomarkers of Response to the Anti-CD37 Antibody Drug Conjugate (ADC) IMGN529

Eugenio Gaudio, PhD, Chiara Tarantelli, PhD, Alberto Arribas, PhD, Luciano Cascione, PhD, Ivo Kwee, PhD, Andrea Rinaldi, PhD, Maurilio Ponzoni, MD, Roberta Pittau Bordone, Georg Stussi, MD, Davide Rossi, MD PhD, Emanuele Zucca, Anastasios Stathis, Callum Sloss, PhD Molecular Biology, Francesco Bertoni, MD
Journal: Blood
Blood (2016) 128 (22): 4187.
https://doi.org/10.1182/blood.V128.22.4187.4187
Published: 2016