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Afshin Samali
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Journal Articles

Synergistic Dual Inhibition of BCR-ABL1 and the Unfolded Protein Response Causes p38 MAPK-Mediated Cell Death and Sensitizes BCR-ABL1 + Acute Lymphoblastic Leukemia to Dexamethasone

Margherita Vieri, MSc, Christian Preisinger, Mirle Schemionek, Azam Salimi, John B. Patterson, Afshin Samali, Tim H Brümmendorf, MD, Iris Appelmann, MD, Behzad Kharabi Masouleh, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4674.
https://doi.org/10.1182/blood-2018-99-110967
Published: 2018
Journal Articles

G2/M Arrest Sensitizes Chronic Myelogenous Leukemia Cells to TRAIL-Induced Apoptosis

David Devlin, Medical, Student, Eva Szegezdi, Post-Doctoral, Researcher, Paavilainen Tanja, Student, Orsolya Orosz, Student, Michael O'Dwyer, MD, FRCPath, Michael Carty, Senior, Lecturer, Afshin Samali, PhD, Séverine Cruet Hennequart, PhD
Journal: Blood
Blood (2010) 116 (21): 4465.
https://doi.org/10.1182/blood.V116.21.4465.4465
Published: 2010
Journal Articles

The BH3 Mimetic, ABT-737, Overcomes Stromal-Mediated Pro-Survival Signals and Synergizes with PHA-767491, a Dual Cdc7/CDK9 Inhibitor, In Acute Myeloid Leukaemia

Ruth C Morrell, MBBCh, FRCPath, Eva Szegezdi, PhD, Anna Halpin-McCormick, BSc, Karen Cawley, BSc, Afshin Samali, PhD, Michael O'Dwyer, MD, FRCPath
Journal: Blood
Blood (2010) 116 (21): 1841.
https://doi.org/10.1182/blood.V116.21.1841.1841
Published: 2010
Journal Articles

PHA767491, a Dual Cdc7/CDK9 Inhibitor, with Potential to Target Both Proliferation and Survival in CLL.

Alessandro Natoni, PhD, Amjad Hayat, MBBS, MRCP, MRCPath, PhD, Alessia Montagnoli, PhD, Grace Callagy, MB, PhD, MRCPI, FRCPath, Afshin Samali, PhD, Corrado Santocanale, PhD, Michael C O'Dwyer, MD, FRCPI, FRCPath
Journal: Blood
Blood (2009) 114 (22): 2366.
https://doi.org/10.1182/blood.V114.22.2366.2366
Published: 2009