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Journal Articles

Role of NF-E2 Related Factor 2 (NRF2) on Chemotherapy Resistance in Acute Myeloid Leukemia (AML) and the Effect of Pharmacological Inhibition of NRF2

Sreeja Karathedath, MSc, Bharathi M Rajamani, M.Phil, Savitha Varatharajan, MSc, Ajay Abraham, MSc, Vikram Mathews, DM, Shaji R Velayudhan, PhD, Poonkuzhali Balasubramanian, PhD
Journal: Blood
Blood (2015) 126 (23): 1272.
https://doi.org/10.1182/blood.V126.23.1272.1272
Published: 2015
Journal Articles

A-Type Proanthocyanidins Prevent Engraftment Of Primary Acute Myelogenous Leukemia Cells In Mice and Exhibit Potentially Novel Anti-Leukemia Mechanisms

Laura M Bystrom, PhD, Hongliang Zong, MD, PhD, Hsiao-Ting Hsu, MS, Neng Yang, MD, PhD, Noa Greenberg, MD, Qinghao Wang, MD, PhD, Catherine Neto, PhD, Maolin Guo, PhD, Stefano Rivella, PhD, Monica L. Guzman, PhD
Journal: Blood
Blood (2013) 122 (21): 3962.
https://doi.org/10.1182/blood.V122.21.3962.3962
Published: 2013
Journal Articles

Bone-Marrow Derived Cells Can Reconstitute GCLM Function in the Sickle Lung

Olufolake Adisa, MD, Samit Ghosh, PhD, Fang Tan, PhD, Prasanthi Chappa, David R. Archer, PhD, Solomon F Ofori-Acquah, PhD
Journal: Blood
Blood (2011) 118 (21): 4836.
https://doi.org/10.1182/blood.V118.21.4836.4836
Published: 2011
Journal Articles

ATM Mutant Lymphoid Tumour Cells Exhibit Impaired Activation of the Redox-Sensitive Nrf2-ARE Detoxification Pathway and Are Differentially Sensitive to Nrf2-Activating Compounds

Victoria J Weston, PhD, Angelo Agathanggelou, PhD, Paul AH Moss, MD, PhD, Pamela R. Kearns, BSc, MBBCh, MRCP, PhD, A. Malcolm R Taylor, PhD, Tatjana Stankovic, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 49.
https://doi.org/10.1182/blood.V116.21.49.49
Published: 2010
Journal Articles

Exploiting the NRF2/Antioxidant Response Element Signaling Pathway to Induce γ-Globin Gene Expression and HbF Production

Elizabeth R. Macari, BS, Rachel J. West, PhD, Christopher H. Lowrey, MD
Journal: Blood
Blood (2010) 116 (21): 2074.
https://doi.org/10.1182/blood.V116.21.2074.2074
Published: 2010
Journal Articles

Metabolomic Evaluation of Normal, In Vivo, Red Cell Aging

Katrin Soldau, Katharina von Loehneysen, PhD, Xiuling Xu, PhD, Jeff S. Friedman, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2035.
https://doi.org/10.1182/blood.V116.21.2035.2035
Published: 2010
Journal Articles

Induction of γ-Globin Gene Expression Via the Nrf2/Antioxidant Response Element Signaling Pathway.

Elizabeth Macari, BS, Rachel West, PhD, William J. Lowrey, Rodwell Mabaera, PhD, Christopher H. Lowrey, MD
Journal: Blood
Blood (2009) 114 (22): 975.
https://doi.org/10.1182/blood.V114.22.975.975
Published: 2009
Journal Articles

HIF1 Induced Glutathione Dysregulation in Platelets Associated with Increased Risk of Vascular Disease in Chuvash Polycythemia.

Heather Gilbert, MD, Donghoon Yoon, PhD, Adelina I Sergueeva, Victor R. Gordeuk, MD, Josef T. Prchal, MD
Journal: Blood
Blood (2008) 112 (11): 1906.
https://doi.org/10.1182/blood.V112.11.1906.1906
Published: 2008
Journal Articles

Mechanisms and Activity of PPARγ-Active Triterpenoids CDDO and CDDO-Me in Leukemias.

Marina Konopleva, MD, PhD, Ismael Samudio, PhD, Twee Tsao, Steven M. Kornblau, MD, Yue-Xi Shi, Teresa McQueen, BS, Rooha Contractor, Michael B. Sporn, MD, Colin J. Meyer, MD, Warren Huff, Stephen H. Safe, PhD, Hagop Kantarjian, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2460.
https://doi.org/10.1182/blood.V106.11.2460.2460
Published: 2005
Journal Articles

Gene Profile during Arsenic Trioxide-Induced Apoptosis in Multiple Myeloma: Strong Anti-Oxidantive Response and Pro-Apoptotic Imbalance.

Alejo A. Morales, PhD, Delia Gutman, MS, Pedro J. Cejas, PhD, Kelvin P. Lee, MD, Lawrence H. Boise, PhD
Journal: Blood
Blood (2005) 106 (11): 5175.
https://doi.org/10.1182/blood.V106.11.5175.5175
Published: 2005