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Journal Articles

Integrated Systems Level Examination of Proteasome Inhibitor Stress Recovery in Myeloma Cells Reveals Druggable Vulnerabilities Linked to Multiple Metabolic Processes

Paula Saavedra-Garcia, PhD, Hibah A Al-Sadah, MSc, Lucy Penfold, PhD, Xiaobei Xiong, MRes, Elena Lopez-Jimenez, PhD, Katarzyna Parzych, PhD, Valentina S Caputo, Kevin Blighe, PhD, Martin F. Kaiser, Paolo Piazza, PhD, Vesela Encheva, PhD, Ambrosius P Snijders, PhD, Hector C Keun, DPhil, Diego Oyarzun, PhD, Denise Thiel, MSc, Zijing Liu, PhD, Mauricio Barahona, PhD, Holger W Auner, MD PhD

Blood (2019) 134 (Supplement_1): 1818.

https://doi.org/10.1182/blood-2019-121549

Published: 2019

Journal Articles

CD38 Knockout Primary NK Cells to Prevent "Fratricide" and Boost Daratumumab Activity

Yuya Nagai, MD, Meisam Naeimi Kararoudi, PhD DVM, Ezgi Elmas, MS, Marcelo Pereira, Syed Abbas Ali, MD, Philip Hollingsworth Imus, MD, Dean Anthony Lee, MD PhD, Gabriel Ghiaur, MD PhD

Blood (2019) 134 (Supplement_1): 870.

https://doi.org/10.1182/blood-2019-129456

Published: 2019

Journal Articles

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Enric Redondo Monte, MSc, BSc, Anja Wilding, MSc, Georg Leubolt, MSc, Paul Kerbs, MSc, Johannes Bagnoli, Wolfgang Hiddemann, MD PhD, Wolfgang Enard, PhD, Sebastian Theurich, MD, Philipp A. Greif, MD PD

Blood (2019) 134 (Supplement_1): 1453.

https://doi.org/10.1182/blood-2019-128378

Published: 2019

Journal Articles

Association between GLUT1 and HbF Levels in Red Blood Cells from Patients with Sickle Cell Disease

Alireza Paikari, MD, Ankush Goyal, MA, Christelle Cousin, PhD, Vincent Petit, DVM, PhD, Vivien A. Sheehan, MD PhD

Blood (2019) 134 (Supplement_1): 2265.

https://doi.org/10.1182/blood-2019-131058

Published: 2019

Journal Articles

Evaluating Metabolic Regulation of Human Erythropoiesis By Profiling Nutrient Transporter Expression

David Justus, MD, Hongxia Yan, MS, John Hale, PhD, Lionel Blanc, PhD, Floriane Bitaudeau, MS, Vincent Petit, DVM, PhD, Sandrina Kinet, PhD, Marc Sitbon, PhD, Naomi Taylor, MD PhD, Mohandas Narla, DSc

Blood (2019) 134 (Supplement_1): 342.

https://doi.org/10.1182/blood-2019-124380

Published: 2019

Journal Articles

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Tasleem Arif, PhD, Raymond Liang, PhD, Maio Lin, Msc, Svetlana Kalmikova, Msc, Artem Kasianov, PhD, Vijay Menon, PhD, Dmitri Papatsenko, PhD, Saghi Ghaffari, PhD MD

Blood (2019) 134 (Supplement_1): 271.

https://doi.org/10.1182/blood-2019-129099

Published: 2019

Journal Articles

Chronic Lymphocytic Leukemia Cells Impair Mitochondrial Fitness in CD8 + T Cells and Impede CAR T Cell Efficacy

Jaco A. C. Van Bruggen, MSc, Anne W. J. Martens, MSc, Joseph A Fraietta, PhD, Tom Hofland, MSc, Sanne Tonino, MD PhD, Eric Eldering, PhD, Mark-David Levin, MDPhD, Peter J. Siska, MD, Sanne Endstra, Jeffrey C Rathmell, PhD, Carl H June, MD, David L. Porter, MD, J. Joseph Melenhorst, PhD, Gerritje J. W. van der Windt, PhD, Arnon P. Kater, MD

Blood (2018) 132 (Supplement 1): 235.

https://doi.org/10.1182/blood-2018-99-115911

Published: 2018

Journal Articles

Upregulation of Tissue Factor May Contribute to Thrombosis in Polycythemia Vera and Essential Thrombocythemia

Brandi Reeves, MD, Soo Jin Kim, MS, Jihyun Song, PhD, Radhika Gangaraju, MD, Rafal Pawlinski, PhD, Perumal Thiagarajan, MD, Victor R. Gordeuk, MD, Nigel S. Key, MBChB, FRCP, Josef T. Prchal, MD

Blood (2018) 132 (Supplement 1): 2513.

https://doi.org/10.1182/blood-2018-99-117812

Published: 2018

Journal Articles

T Cell Metabolism and Memory

Jeffrey C Rathmell, PhD

Blood (2018) 132 (Supplement 1): SCI-6.

https://doi.org/10.1182/blood-2018-99-109535

Published: 2018

Journal Articles

B-Cell Receptor Signaling Drives Glycolysis in Chronic Lymphocytic Leukemia Cells

Andrew James Clear, BSc, Annalisa D'Avola, PhD, Samir G. Agrawal, BSc, PhD MBChB, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, John G. Gribben, John Riches, MD PhD

Blood (2018) 132 (Supplement 1): 3121.

https://doi.org/10.1182/blood-2018-99-112860

Published: 2018

Journal Articles

CD28 Induces Metabolic Fitness in Multiple Myeloma for ROS-Dependent Survival

Adam Utley, BS, BA, Peng Peng, Wensheng Liu, Daniella Ventrone, Kelvin P. Lee, MD

Blood (2018) 132 (Supplement 1): 3220.

https://doi.org/10.1182/blood-2018-99-119496

Published: 2018

Journal Articles

Role of Glucose Transporter 1 in Graft-Versus-Host Disease and Graft-Versus-Tumor Effect

Ying Huang, MD PhD, Yiqun Jiao, MD, Peijie Shi, MD PhD, Xiaoli Nie, MD PhD, Wei Huang, MD PhD, Michael Choi, Andrew N Macintyre, Amanda Nichols, Nancie J. MacIver, MD PhD, Nelson J. Chao, MDM.B.A, Jeffrey Rathmell, PhD, Benny J. Chen, MD

Blood (2017) 130 (Supplement 1): 1891.

https://doi.org/10.1182/blood.V130.Suppl_1.1891.1891

Published: 2017

Journal Articles

Reduced Chemosensitivity of FLT3/ITD Mutated Cells to Cytarabine and Quizartinib Under Hypoxic Conditions

Heiko Konig, MD PhD, Adriana L Rogozea, Garrett H Kinnebrew, MD, Mircea Ivan, MD PhD

Blood (2016) 128 (22): 1579.

https://doi.org/10.1182/blood.V128.22.1579.1579

Published: 2016

Journal Articles

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

Jun-ichirou Yasunaga, MDPhD, Rie Furuta, Michi Miura, Kenji Sugata, Akatsuki Saito, Akari Hirofumi, Takaharu Ueno, Norihiro Takenouchi, Jun-ichi Fujisawa, Masakazu Shimizu, Fumihiko Matsuda, MD PhD, Anat Melamed, Charles R. M. Bangham, Masao Matsuoka, MD PhD

Blood (2016) 128 (22): 1343.

https://doi.org/10.1182/blood.V128.22.1343.1343

Published: 2016

Journal Articles

CD28 Induces Mitochondrial Respiration through Irf4 for Long Lived Plasma Cells Survival

Adam T. Utley, BS, BA, Louise Carlson, BS, Kelvin P. Lee, MD

Blood (2016) 128 (22): 128.

https://doi.org/10.1182/blood.V128.22.128.128

Published: 2016

Journal Articles

Upregulation of Thrombo-Inflammatory Pathways May Contribute to Increased Thrombotic Risk in Polycythemia Vera and Essential Thrombocythemia

Radhika Gangaraju, MD, Soo Jin Kim, MS, Jihyun Song, PhD, Sabina Swierczek, PhD, Perumal Thiagarajan, MD, Josef T. Prchal, MD

Blood (2016) 128 (22): 3143.

https://doi.org/10.1182/blood.V128.22.3143.3143

Published: 2016

Journal Articles

Human Double-Negative Regulatory T Cells Selectively Suppress mTOR Signaling and Metabolic Reprogramming of Conventional T Cells

Tabea Haug, Heiko Bruns, PhD, Michael Aigner, Andreas Mackensen, Simon Voelkl, PhD

Blood (2016) 128 (22): 3694.

https://doi.org/10.1182/blood.V128.22.3694.3694

Published: 2016

Journal Articles

Transcriptional Control of Glucose and Energy Supply Prevents Oncogenic Signaling and B Cell Transformation

Lai N Chan, PhD, Zhengshan Chen, MD PhD, Gang Xiao, PhD, Jaewoong Lee, PhD, Huimin Geng, PhD, Hurtz Christian, PhD, Valeria Cazzaniga, PhD, Giovanni Cazzaniga, PhD, Ross A Dickins, PhD, Markus Müschen, MD PhD

Blood (2016) 128 (22): 437.

https://doi.org/10.1182/blood.V128.22.437.437

Published: 2016

Journal Articles

Cereblon Deficiency Leads to Alteration in c-Myc Regulated Genes, Increased Glucose Uptake and Resistance to JQ1 Bromodomain Inhibition

Matthew S Beatty, PhD, Rebecca S Hesterberg, BA, Ying Han, MD, Eric Padron, MD, Adam W Mailloux, PhD, Sean Yoder, M.S, Anjali M Rajadhyaksha, PhD, Alan F. List, MD, Pearlie K Epling-Burnette, PhD

Blood (2015) 126 (23): 286.

https://doi.org/10.1182/blood.V126.23.286.286

Published: 2015

Journal Articles

Glucose Transporter 3 in Platelets Facilitates Alpha-Granule Mediated Glucose Uptake, Driving Intragranular Glycolysis That Is Required for Platelet Degranulation and Activation

Fidler P.L Trevor, Elizabeth Middleton, MD, Jesse W Rowley, PhD, Luc Boudreau, PhD, Robert A. Campbell, PhD, Rhonda Souvenir, PhD, Eric Boilard, PhD, E. Dale Abel, MD PhD, Andrew S. Weyrich, PhD

Blood (2015) 126 (23): 417.

https://doi.org/10.1182/blood.V126.23.417.417

Published: 2015

NARROW

Integrated Systems Level Examination of Proteasome Inhibitor Stress Recovery in Myeloma Cells Reveals Druggable Vulnerabilities Linked to Multiple Metabolic Processes

CD38 Knockout Primary NK Cells to Prevent "Fratricide" and Boost Daratumumab Activity

Loss of ZBTB7A Enhances Glycolysis and Beta Oxidation in Myeloid Leukemia

Association between GLUT1 and HbF Levels in Red Blood Cells from Patients with Sickle Cell Disease

Evaluating Metabolic Regulation of Human Erythropoiesis By Profiling Nutrient Transporter Expression

Activated but Not Quiescent Hematopoietic Stem Cells Rely Readily on Glycolysis As Their Main Source of Energy

Chronic Lymphocytic Leukemia Cells Impair Mitochondrial Fitness in CD8 + T Cells and Impede CAR T Cell Efficacy

Upregulation of Tissue Factor May Contribute to Thrombosis in Polycythemia Vera and Essential Thrombocythemia

T Cell Metabolism and Memory

B-Cell Receptor Signaling Drives Glycolysis in Chronic Lymphocytic Leukemia Cells

CD28 Induces Metabolic Fitness in Multiple Myeloma for ROS-Dependent Survival

Role of Glucose Transporter 1 in Graft-Versus-Host Disease and Graft-Versus-Tumor Effect

Reduced Chemosensitivity of FLT3/ITD Mutated Cells to Cytarabine and Quizartinib Under Hypoxic Conditions

Hematopoietic Stem Cell Infected with HTLV-1 Functions As a Viral Reservoir In Vivo

CD28 Induces Mitochondrial Respiration through Irf4 for Long Lived Plasma Cells Survival

Upregulation of Thrombo-Inflammatory Pathways May Contribute to Increased Thrombotic Risk in Polycythemia Vera and Essential Thrombocythemia

Human Double-Negative Regulatory T Cells Selectively Suppress mTOR Signaling and Metabolic Reprogramming of Conventional T Cells

Transcriptional Control of Glucose and Energy Supply Prevents Oncogenic Signaling and B Cell Transformation

Cereblon Deficiency Leads to Alteration in c-Myc Regulated Genes, Increased Glucose Uptake and Resistance to JQ1 Bromodomain Inhibition

Glucose Transporter 3 in Platelets Facilitates Alpha-Granule Mediated Glucose Uptake, Driving Intragranular Glycolysis That Is Required for Platelet Degranulation and Activation

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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