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Journal Articles

Discovery of DWP213388, a Potent ITK and BTK Selective Dual Inhibitor with Excellent Efficacy and Safety, for Treating Gvhd

Deokki Eom, BS, Jae Hun Jung, Eun Kyung KIM, PhD, Wolyoung Kim, Qingri Li, Jaehyun Jung, Sohee Im, Yong Dae Shin, Hyaejung Hyun, Joon Seok Park

Blood (2019) 134 (Supplement_1): 4426.

https://doi.org/10.1182/blood-2019-126839

Published: 2019

Journal Articles

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

Ingrid G Winkler, PhD, Valerie Barbier, Masters, Joshua Tay, PhD, Jean-Pierre Levesque, PhD, John L. Magnani, PhD, Corrine E Fiveash, BSc(Hons), Johanna D Erbani

Blood (2019) 134 (Supplement_1): 2657.

https://doi.org/10.1182/blood-2019-132212

Published: 2019

Journal Articles

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Jia Yu, Xuan Yuan, MD MSc, Kang Zhou, Daniel White, Samuel A. Merrill, MD PhD, Robert A. Brodsky, MD

Blood (2018) 132 (Supplement 1): 3748.

https://doi.org/10.1182/blood-2018-99-119445

Published: 2018

Journal Articles

Placebo Controlled Functional Analysis of Eltrombopag in a Preclinical Xenograft Model of Myelodysplastic Syndromes (MDS)

Nanni Schmitt, MSc, Eva Altrock, PhD, Johann-Christoph Jann, MD, Johanna Flach, PhD, Carla Sens-Albert, PhD, Justine Danner, Stefanie Uhlig, Jovita Pressler, Iris Palme, Verena Nowak, Julia Obländer, Lena Drangmeister, MD, Franziska La Meir, MD, Georgia Metzgeroth, MD, Florian Nolte, MD, Wolf-Karsten Hofmann, Daniel Nowak, MD

Blood (2018) 132 (Supplement 1): 942.

https://doi.org/10.1182/blood-2018-99-116341

Published: 2018

Journal Articles

In Vitro Comparison of Different TKI Activity in T-Cell Populations: Selective Sparing of Treg By Nilotinib

Elena Marinelli Busilacchi, ScD, Andrea Costantini, MD, Nadia Viola, ScD, Benedetta Costantini, MD, Antonella Poloni, MD, Jacopo Olivieri, MD, Francesco Saraceni, MD, Giorgia Mancini, MD, Attilio Olivieri, MD

Blood (2016) 128 (22): 5774.

https://doi.org/10.1182/blood.V128.22.5774.5774

Published: 2016

Journal Articles

EC-18 (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol) Exhibits the Immune Regulatory Role through HSC Differentiation of Bone Marrow Cells in Mice

Ha-Reum Lee, PhD, Su-Hyun Shin, Nina Yoo, Sun Young Yoon, PhD, Myung-Hwan Kim, MD PhD, Cheolwon Suh, Ki-Young Sohn, Heung-Jae Kim, PhD, Yong-Hae Han, PhD, Saeho Chong, PhD, Jae Wha Kim, PhD

Blood (2015) 126 (23): 4757.

https://doi.org/10.1182/blood.V126.23.4757.4757

Published: 2015

Journal Articles

Increased Circulating Plasma Cells On Multiparametric Flow Cytometry As An Independent Prognostic Biomarker In Newly Diagnosed Multiple Myeloma: Implications For Redefining High-Risk Myeloma

Wilson I Gonsalves, MD, Vinay Gupta, MBBS, S. Vincent Rajkumar, MD, William G Morice, MD, PhD, Michael M Timm, Preet Paul Singh, MD, Angela Dispenzieri, MD, Francis K Buadi, MD, Martha Q Lacy, MD, Prashant Kapoor, MD, Morie A Gertz, MD, MACP, Shaji K Kumar, MD

Blood (2013) 122 (21): 1842.

https://doi.org/10.1182/blood.V122.21.1842.1842

Published: 2013

Journal Articles

Prognostic Value Of Quantifying Circulating Plasma Cells By Multiparametric Flow Cytometry In Patients With Relapsed Multiple Myeloma

Wilson I Gonsalves, MD, Vinay Gupta, MBBS, S. Vincent Rajkumar, MD, William G Morice, MD, PhD, Michael M Timm, Preet Paul Singh, MD, Morie A Gertz, MD, Francis K Buadi, MD, Martha Q Lacy, MD, Prashant Kapoor, MD, Angela Dispenzieri, MD, Shaji K Kumar, MD

Blood (2013) 122 (21): 754.

https://doi.org/10.1182/blood.V122.21.754.754

Published: 2013

Journal Articles

BET Bromodomain Inhibition Reduces Leukemic Burden and Prolongs Survival In The Eμ-TCL1 Transgenic Mouse Model Of Chronic Lymphocytic Leukemia (CLL) Independent Of TP53 Mutation Status

Connie A Larsson, Kensuke Kojima, MD, PhD, Yong Wang, PhD, Nicholas Navin, PhD, Miguel Gallardo, PhD, Daniel Primo, Jose L. Rojas, Joaquin Martinez, Taghi Manshouri, Ph.D., Hun Ju Lee, MD, James E Bradner, MD, Juan Ballesteros, Sean M. Post, PhD, Guillermina (Gigi) Lozano, PhD, Alfonso Quintás-Cardama, MD

Blood (2013) 122 (21): 876.

https://doi.org/10.1182/blood.V122.21.876.876

Published: 2013

Journal Articles

Highly Sensitive Bioluminescence in Vivo Imaging Enables Individualized Preclinical Treatment Trials On Patients ALL Tumor Cells Growing in Mice.

Nadia Terziyska, Catarina Castro Alves, Manfred Ogris, Ernst Wagner, Renier J Brentjens, MD, PhD, Martin A. Horstmann, MD, Leticia Quintanilla-Martinez, MD, PhD, Irmela Jeremias, MD

Blood (2012) 120 (21): 2602.

https://doi.org/10.1182/blood.V120.21.2602.2602

Published: 2012

Journal Articles

Targeting STAT5 Expression Resulted in Molecular Response Improvement in Patients with Chronic Phase CML Treated with Imatinib

Philippe Rousselot, MD, PhD, Lydia Roy, MD, Gabriel Etienne, MD, PHD, Laurence Legros, MD, PhD, Aude Charbonnier, MD, PhD, Valérie Coiteux, MD, Pascale Cony-Makhoul, MD, Francois-Xavier Mahon, MD, PhD, Joelle Guilhot, PhD, Jean-Michel Cayuela, Francis Relouzat, Philippe Leboulche, Stephane Prost

Blood (2012) 120 (21): 696.

https://doi.org/10.1182/blood.V120.21.696.696

Published: 2012

Journal Articles

Randomized Phase II Study of BLP25 Liposome Vaccine (L-BLP25) in Patients with Multiple Myeloma

Eva Rossmann, Anders Österborg, Eva Löfvenberg, Aniruddha Choudhury, Ulf Forssmann, Stefanie Senger, Andreas Schröder, Håkan Mellstedt

Blood (2011) 118 (21): 2927.

https://doi.org/10.1182/blood.V118.21.2927.2927

Published: 2011

Journal Articles

Sox4 and CREB Cooperate in Myeloid Transformation,

Salemiz Sandoval, Ph.D., Michelle Cho, Christina Kraus, Er-Chieh Cho, Ph.D., Linda Wolff, PhD, Kathleen M Sakamoto, MD, PhD

Blood (2011) 118 (21): 3452.

https://doi.org/10.1182/blood.V118.21.3452.3452

Published: 2011

Journal Articles

A Novel FACS Assay for Absolute Quantification of CD20 on B-Cells and Determination of CD20 Occupancy in Whole Blood Samples Shows a Higher Binding Strength of Obinutuzumab (GA101) to CD20 on B-Lymphocytes

Drifa Beroual, BSc, Danièle Boulay-Moine, MSc, Carole Badoil, MSc, Christian Klein, PhD, Maxime Moulard, PhD

Blood (2011) 118 (21): 4611.

https://doi.org/10.1182/blood.V118.21.4611.4611

Published: 2011

Journal Articles

DNA damage–induced transcriptional program in CLL: biological and diagnostic implications for functional p53 testing

Julia Mohr, Hanne Helfrich, Maxi Fuge, Eric Eldering, Andreas Bühler, Dirk Winkler, Matthias Volden, Arnon P. Kater, Daniel Mertens, Doreen Te Raa, Hartmut Döhner, Stephan Stilgenbauer, Thorsten Zenz

Blood (2011) 117 (5): 1622–1632.

https://doi.org/10.1182/blood-2010-08-300160

Published: 2011

Includes: Supplemental data

Journal Articles

B-Cell Lymphoma In Eu-Mir-17~92 Transgenic Mice

Sukhinder Sandhu, BSc, MSc, Reid Neinast, Veronica Balatti, PhD, Francesca Lovat, PhD, Stefano Volinia, PhD, Ramiro Garzon, MD, Yuri Pekarsky, PhD, Carlo M. Croce, MD

Blood (2010) 116 (21): 774.

https://doi.org/10.1182/blood.V116.21.774.774

Published: 2010

Journal Articles

Clinical Evidence That Oct-4 + ssea-4 + Very Small Embryonic Like Stem Cells (VSEL) Are Mobilized into Peripheral Blood in Patients with Acute Myocardial Infarction (AMI): A Novel Prognostic Indicator

Wojciech Wojakowski, MD, PhD, Michal Tendera, MD, PhD, Magdalena Kucia, PhD, Ewa K Zuba-Surma, PhD, Edyta Paczkowska, MD, PhD, Joanna Ciosek, MD, Maciek Halasa, MD, PhD, Marek Krol, MD, PhD, Maciej Kazmierski, MD, PhD, Andrzej Ochala, Janina Ratajczak, MD, PhD, Mariusz Z Ratajczak, MD, PhD

Blood (2008) 112 (11): 2894.

https://doi.org/10.1182/blood.V112.11.2894.2894

Published: 2008

Journal Articles

Tubacin, An Inhibitor of HDAC6, Induces Apoptosis of Acute Lymphoblastic Leukemia Cells in Vitro and in Vivo through a Na+/K+ATPase-Dependent Pathway.

Agustin Rodriguez-Gonzalez, Ph.D., Tiffany Simms-Waldrip, M.D., Alan K. Ikeda, M.D., Tara Lin, M.D., Brett Lomenick, Grace Aldana-Masangkay, Ralph Mazitschek, Ph.D., James Bradner, Cecilia Fu, M.D., Kathleen M. Sakamoto, M.D., Ph.D.

Blood (2008) 112 (11): 1923.

https://doi.org/10.1182/blood.V112.11.1923.1923

Published: 2008

Journal Articles

Study on the Ratio and Function of Macrophages in the Patients with BMMNCCoombs Test(+) Hematocytopenia

Rong Fu, Yi hao Wang, Zonghong Shao, Jin Chen, Lijuan Li, Hui Liu, Huaquan Wang, Limin Xing, Hong Liu

Blood (2008) 112 (11): 4656.

https://doi.org/10.1182/blood.V112.11.4656.4656

Published: 2008

Journal Articles

Peptide Vaccine Preparation and Validation with a Bio-Assay

Anita Schmitt, Clemens Bechter, Junxia Yao, Marlies Goetz, Birgit Maccari, Peter Schauwecker, Markus Wiesneth, Michael Schmitt

Blood (2008) 112 (11): 5444.

https://doi.org/10.1182/blood.V112.11.5444.5444

Published: 2008

NARROW

Discovery of DWP213388, a Potent ITK and BTK Selective Dual Inhibitor with Excellent Efficacy and Safety, for Treating Gvhd

Blocking Vascular Niche E-Selectin Dampens AML Stem Cell Regeneration/Survival Potential In Vivo By Inhibiting MAPK/ERK and PI3K/AKT Signalling Pathways

An Alternative Pathway Specific Flow Cytometric Assay to Detect Complement Activation in Atypical Hemolytic Uremic Syndrome (aHUS)

Placebo Controlled Functional Analysis of Eltrombopag in a Preclinical Xenograft Model of Myelodysplastic Syndromes (MDS)

In Vitro Comparison of Different TKI Activity in T-Cell Populations: Selective Sparing of Treg By Nilotinib

EC-18 (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol) Exhibits the Immune Regulatory Role through HSC Differentiation of Bone Marrow Cells in Mice

Increased Circulating Plasma Cells On Multiparametric Flow Cytometry As An Independent Prognostic Biomarker In Newly Diagnosed Multiple Myeloma: Implications For Redefining High-Risk Myeloma

Prognostic Value Of Quantifying Circulating Plasma Cells By Multiparametric Flow Cytometry In Patients With Relapsed Multiple Myeloma

BET Bromodomain Inhibition Reduces Leukemic Burden and Prolongs Survival In The Eμ-TCL1 Transgenic Mouse Model Of Chronic Lymphocytic Leukemia (CLL) Independent Of TP53 Mutation Status

Highly Sensitive Bioluminescence in Vivo Imaging Enables Individualized Preclinical Treatment Trials On Patients ALL Tumor Cells Growing in Mice.

Targeting STAT5 Expression Resulted in Molecular Response Improvement in Patients with Chronic Phase CML Treated with Imatinib

Randomized Phase II Study of BLP25 Liposome Vaccine (L-BLP25) in Patients with Multiple Myeloma

Sox4 and CREB Cooperate in Myeloid Transformation,

A Novel FACS Assay for Absolute Quantification of CD20 on B-Cells and Determination of CD20 Occupancy in Whole Blood Samples Shows a Higher Binding Strength of Obinutuzumab (GA101) to CD20 on B-Lymphocytes

DNA damage–induced transcriptional program in CLL: biological and diagnostic implications for functional p53 testing

B-Cell Lymphoma In Eu-Mir-17~92 Transgenic Mice

Clinical Evidence That Oct-4 + ssea-4 + Very Small Embryonic Like Stem Cells (VSEL) Are Mobilized into Peripheral Blood in Patients with Acute Myocardial Infarction (AMI): A Novel Prognostic Indicator

Tubacin, An Inhibitor of HDAC6, Induces Apoptosis of Acute Lymphoblastic Leukemia Cells in Vitro and in Vivo through a Na+/K+ATPase-Dependent Pathway.

Study on the Ratio and Function of Macrophages in the Patients with BMMNCCoombs Test(+) Hematocytopenia

Peptide Vaccine Preparation and Validation with a Bio-Assay

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American Society of Hematology

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