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Journal Articles

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Denis F. Noubouossie, Michael W. Henderson, Micah Mooberry, Anton Ilich, Patrick Ellsworth, Mark Piegore, Sarah C. Skinner, Rafal Pawlinski, Ian Welsby, Thomas Renné, Maureane Hoffman, Dougald M. Monroe, Nigel S. Key

Blood (2020) 135 (10): 755–765.

https://doi.org/10.1182/blood.2019001643

Published: 2020

Includes: Supplemental data

Journal Articles

Interrogation of the Coagulation Cascade Acute Coronary Syndrome Using Novel Elisa-Based Assays for Single Protease Quantification

Jens Posma, MSc, Rene van Oerle, Diane Fens, Jose govers Riemslag, PhD, Julia Mueller, PhD, Stefan Heitmeier, PhD, Hugo ten Cate, MD PhD, Henri M.H. Spronk, PhD

Blood (2018) 132 (Supplement 1): 5013.

https://doi.org/10.1182/blood-2018-99-118353

Published: 2018

Journal Articles

Discovery and Characterization of a Highly Specific Antibody Inhibitor of Factor XIIa, and the Subsequent Generation of a Factor XIIa/Plasma Kallikrein Bispecific Antibody

Blood (2015) 126 (23): 2268.

https://doi.org/10.1182/blood.V126.23.2268.2268

Published: 2015

Journal Articles

Simultaneous Measurement of Thrombin Generation and Fibrin Formation in Whole Blood Applying Continuous Flow Is Predictive for the Amount of Blood Loss during/after Cardiothoracic Surgery

Leonie Pelkmans, Anne Bouwhuis, Evelien Schurgers, PhD, Theo Lindhout, PhD, Dana Huskens, PhD, Coenraad Hemker, PhD, Marcus Lancé, MD, Bas De Laat, PhD, Hilde Kelchtermans, PhD

Blood (2014) 124 (21): 2813.

https://doi.org/10.1182/blood.V124.21.2813.2813

Published: 2014

Journal Articles

Inhibition of Factor XIIa-Mediated Factor XI Activation Reduces Infarct Size in a Mouse Model of Myocardial Ischemia and Reperfusion

Christina U Lorentz, PhD, Norah G Verbout, PhD, Zhiping Cao, Helen Liu, Owen J.T. McCarty, PhD, Erik I. Tucker, PhD, Andras Gruber, MD, Donna Van Winkle, PhD

Blood (2014) 124 (21): 2873.

https://doi.org/10.1182/blood.V124.21.2873.2873

Published: 2014

Journal Articles

Response: Platelets do not generate activated factor XII—how inappropriate experimental models have led to misleading conclusions

Niklas Boknäs, Lars Faxälv, Jakob O. Ström, Pentti Tengvall, Elvar Theodorsson, Sofia Ramström, Tomas L. Lindahl

Blood (2014) 124 (10): 1692–1694.

https://doi.org/10.1182/blood-2014-04-566067

Published: 2014

Journal Articles

The dimeric structure of factor XI and zymogen activation

Yipeng Geng, Ingrid M. Verhamme, Stephen B. Smith, Mao-fu Sun, Anton Matafonov, Qiufang Cheng, Stephanie A. Smith, James H. Morrissey, David Gailani

Blood (2013) 121 (19): 3962–3969.

https://doi.org/10.1182/blood-2012-12-473629

Published: 2013

Journal Articles

Antibodies to Human Factor XII with Antithrombotic Properties

Anton Matafonov, MD, Adam E. Gailani, Stephanie L. Grach, Philberta Y Leung, PhD, Qiufang Cheng, MD, Yipeng Geng, Owen J.T. McCarty, PhD, Erik I Tucker, PhD, Thomas Renne, MD, PhD, James H. Morrissey, PhD, Andras Gruber, MD, David Gailani, MD

Blood (2012) 120 (21): 1106.

https://doi.org/10.1182/blood.V120.21.1106.1106

Published: 2012

Journal Articles

The Interaction of Coagulation Factor XI with Polyphosphate

Yipeng Geng, Ingrid M. Verhamme, PhD, Qiufang Cheng, MD, Anton Matafonov, MD, Stephen B. Smith, PhD, Mao-fu Sun, Stephanie A. Smith, DVM, MS, James H. Morrissey, PhD, David Gailani, MD

Blood (2012) 120 (21): 498.

https://doi.org/10.1182/blood.V120.21.498.498

Published: 2012

Journal Articles

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

Erik I. Tucker, PhD, Ulla M Marzec, MS, Philberta Y Leung, PhD, Stephen R Hanson, PhD, Prof., Norah G Verbout, PhD, Sawan Hurst, MS, Owen J.T. McCarty, PhD, David Gailani, MD, Andras Gruber, MD

Blood (2011) 118 (21): 1173.

https://doi.org/10.1182/blood.V118.21.1173.1173

Published: 2011

Journal Articles

Taking the brakes off?

James H. Morrissey

Blood (2011) 117 (15): 3939–3940.

https://doi.org/10.1182/blood-2011-02-337717

Published: 2011

Journal Articles

New Insights Into Factor XI Function: From Biochemistry to Animal Models

David Gailani, MD

Blood (2010) 116 (21): SCI-20.

https://doi.org/10.1182/blood.V116.21.SCI-20.SCI-20

Published: 2010

Journal Articles

Factor XI Inhibitor Antibody Treatment Improves Survival In a Murine Polymicrobial Sepsis Model

Erik I Tucker, PhD, Melani Helm, BS, Owen JT McCarty, PhD, Sawan Hurst, MS, David Gailani, MD, Andras Gruber, MD

Blood (2010) 116 (21): 820.

https://doi.org/10.1182/blood.V116.21.820.820

Published: 2010

Journal Articles

Plasma Serum Amyloid A Levels Are Increased In Venous Thrombosis Patients and Are Correlated with Blood Coagulability

Hiroshi Deguchi, MD, PhD, Darlene J Elias, MD, Silvia Navarro, PhD, Francisco Espana, PhD, John H. Griffin, PhD

Blood (2010) 116 (21): 155.

https://doi.org/10.1182/blood.V116.21.155.155

Published: 2010

Journal Articles

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Qiufang Cheng, Erik I. Tucker, Meghann S. Pine, India Sisler, Anton Matafonov, Mao-fu Sun, Tara C. White-Adams, Stephanie A. Smith, Stephen R. Hanson, Owen J. T. McCarty, Thomas Renné, András Gruber, David Gailani

Blood (2010) 116 (19): 3981–3989.

https://doi.org/10.1182/blood-2010-02-270918

Published: 2010

Includes: Supplemental data

Journal Articles

Coagulation Factor XIIa Activates Platelets and Is the Physiological Agonist of Protease-Activated Receptor 3.

Yingying Mao, MS, Todd M Getz, BS, Jianguo Jin, MD, Satya P. Kunapuli, Ph.D.

Blood (2009) 114 (22): 770.

https://doi.org/10.1182/blood.V114.22.770.770

Published: 2009

Journal Articles

Factor XI Contributes to Thrombin Generation in the Absence of Factor XIIa

Anton Matafonov, Dmitri Kravtsov, Erik I. Tucker, Mao-fu Sun, John P. Sheehan, MD, Andras Gruber, MD, David Gailani

Blood (2008) 112 (11): 3082.

https://doi.org/10.1182/blood.V112.11.3082.3082

Published: 2008

Journal Articles

Prolylcarboxypeptidase Murine Hypomorphs Are Hypertensive and Prothrombotic

Gregory N Adams, Yihua Zhou, Gretchen Larusch, Marvin T Nieman, PhD, Brian Hoit, PhD, Gretta Jacobs, MD, Xin Yu, Sc.D., Fakhri Mahdi, Zia Shariat-Madar, PhD, Louis D’Alecy, PhD, Yoshio Okada, Alvin H. Schmaier, MD

Blood (2008) 112 (11): 3915.

https://doi.org/10.1182/blood.V112.11.3915.3915

Published: 2008

Journal Articles

Contribution of Intrinsic and Extrinsic Coagulation Pathways to Thrombus Formation in the Mouse Carotid Artery.

Antonella Zampolli, PhD, Patrizia Marchese, PhD, Wolfram Ruf, MD, Nigel Mackman, PhD, Zaverio M. Ruggeri, MD

Blood (2008) 112 (11): 1900.

https://doi.org/10.1182/blood.V112.11.1900.1900

Published: 2008

Journal Articles

Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow

Uzoma M. Okorie, William S. Denney, Manash S. Chatterjee, Keith B. Neeves, Scott L. Diamond

Blood (2008) 111 (7): 3507–3513.

https://doi.org/10.1182/blood-2007-08-106229

Published: 2008

Includes: Supplemental data

NARROW

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Interrogation of the Coagulation Cascade Acute Coronary Syndrome Using Novel Elisa-Based Assays for Single Protease Quantification

Discovery and Characterization of a Highly Specific Antibody Inhibitor of Factor XIIa, and the Subsequent Generation of a Factor XIIa/Plasma Kallikrein Bispecific Antibody

Simultaneous Measurement of Thrombin Generation and Fibrin Formation in Whole Blood Applying Continuous Flow Is Predictive for the Amount of Blood Loss during/after Cardiothoracic Surgery

Inhibition of Factor XIIa-Mediated Factor XI Activation Reduces Infarct Size in a Mouse Model of Myocardial Ischemia and Reperfusion

Response: Platelets do not generate activated factor XII—how inappropriate experimental models have led to misleading conclusions

The dimeric structure of factor XI and zymogen activation

Antibodies to Human Factor XII with Antithrombotic Properties

The Interaction of Coagulation Factor XI with Polyphosphate

Apple Domain-Specific Anti-Factor XI Antibodies Inhibit Venous-Type Thrombosis with Improved Hemostatic Safety Profiles Compared to Enoxaparin in Primates

Taking the brakes off?

New Insights Into Factor XI Function: From Biochemistry to Animal Models

Factor XI Inhibitor Antibody Treatment Improves Survival In a Murine Polymicrobial Sepsis Model

Plasma Serum Amyloid A Levels Are Increased In Venous Thrombosis Patients and Are Correlated with Blood Coagulability

A role for factor XIIa–mediated factor XI activation in thrombus formation in vivo

Coagulation Factor XIIa Activates Platelets and Is the Physiological Agonist of Protease-Activated Receptor 3.

Factor XI Contributes to Thrombin Generation in the Absence of Factor XIIa

Prolylcarboxypeptidase Murine Hypomorphs Are Hypertensive and Prothrombotic

Contribution of Intrinsic and Extrinsic Coagulation Pathways to Thrombus Formation in the Mouse Carotid Artery.

Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow

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American Society of Hematology

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ASH Publications

American Society of Hematology

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